ZA200204268B - Gastroretentive controlled release pharmaceutical dosage forms. - Google Patents

Gastroretentive controlled release pharmaceutical dosage forms.

Info

Publication number
ZA200204268B
ZA200204268B ZA200204268A ZA200204268A ZA200204268B ZA 200204268 B ZA200204268 B ZA 200204268B ZA 200204268 A ZA200204268 A ZA 200204268A ZA 200204268 A ZA200204268 A ZA 200204268A ZA 200204268 B ZA200204268 B ZA 200204268B
Authority
ZA
South Africa
Prior art keywords
polymers
controlled release
dosage forms
pharmaceutical dosage
release pharmaceutical
Prior art date
Application number
ZA200204268A
Other languages
English (en)
Inventor
Michael Friedman
Eran Lavy
Eytan Klausner
Amnon Hoffman
Original Assignee
Yissum Res Dev Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yissum Res Dev Co filed Critical Yissum Res Dev Co
Publication of ZA200204268B publication Critical patent/ZA200204268B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA200204268A 1999-11-29 2002-05-28 Gastroretentive controlled release pharmaceutical dosage forms. ZA200204268B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL13319699A IL133196A0 (en) 1999-11-29 1999-11-29 Gastroretentive controlled release pharmaceutical dosage forms

Publications (1)

Publication Number Publication Date
ZA200204268B true ZA200204268B (en) 2003-08-28

Family

ID=11073546

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200204268A ZA200204268B (en) 1999-11-29 2002-05-28 Gastroretentive controlled release pharmaceutical dosage forms.

Country Status (12)

Country Link
US (1) US6685962B2 (cg-RX-API-DMAC7.html)
EP (1) EP1235557B1 (cg-RX-API-DMAC7.html)
JP (1) JP4679020B2 (cg-RX-API-DMAC7.html)
AT (1) ATE300286T1 (cg-RX-API-DMAC7.html)
AU (1) AU783062B2 (cg-RX-API-DMAC7.html)
CA (1) CA2392361C (cg-RX-API-DMAC7.html)
DE (1) DE60021604T2 (cg-RX-API-DMAC7.html)
ES (1) ES2243327T3 (cg-RX-API-DMAC7.html)
IL (2) IL133196A0 (cg-RX-API-DMAC7.html)
RU (1) RU2002114348A (cg-RX-API-DMAC7.html)
WO (1) WO2001037812A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA200204268B (cg-RX-API-DMAC7.html)

Families Citing this family (90)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040219186A1 (en) * 2001-08-16 2004-11-04 Ayres James W. Expandable gastric retention device
TWI312285B (en) * 2001-10-25 2009-07-21 Depomed Inc Methods of treatment using a gastric retained gabapentin dosage
AUPR951501A0 (en) * 2001-12-14 2002-01-24 Smart Drug Systems Inc Modified sustained release pharmaceutical system
US20040192582A1 (en) 2002-12-19 2004-09-30 Burnett Daniel R. Ingestible formulations for transient, noninvasive reduction of gastric volume
US7554452B2 (en) * 2003-07-18 2009-06-30 Cary Cole Ingestible tracking and locating device
JP4988345B2 (ja) * 2003-09-04 2012-08-01 ザ・ユナイテッド・ステイツ・オブ・アメリカ・アズ・リプレゼンティッド・バイ・ザ・デパートメント・オブ・ヴェテランズ・アフェアーズ 眼用ハイドロゲルナノコンポジット
JP2007507491A (ja) * 2003-09-29 2007-03-29 シージェー コーポレーション 徐放性製剤
CA2549195A1 (en) * 2003-12-09 2005-06-23 Spherics, Inc. Bioadhesive polymers with catechol functionality
US20080089933A1 (en) * 2006-10-16 2008-04-17 Amir Alon Device and method for reducing calorie intake
US20050196355A1 (en) * 2004-03-03 2005-09-08 Constantine Georgiades Film products having controlled disintegration properties
US8007827B2 (en) * 2004-04-02 2011-08-30 Impax Laboratories, Inc. Pharmaceutical dosage forms having immediate release and/or controlled release properties
US8226977B2 (en) 2004-06-04 2012-07-24 Teva Pharmaceutical Industries Ltd. Pharmaceutical composition containing irbesartan
US20080311191A1 (en) * 2004-08-27 2008-12-18 Avinash Nangia Multi-Layer Tablets and Bioadhesive Dosage Forms
CA2592605C (en) * 2004-12-27 2010-12-07 Eisai R&D Management Co., Ltd. Method for stabilizing anti-dementia drug
US20070129402A1 (en) * 2004-12-27 2007-06-07 Eisai Research Institute Sustained release formulations
US20060246003A1 (en) * 2004-12-27 2006-11-02 Eisai Co. Ltd. Composition containing anti-dementia drug
US20060280789A1 (en) * 2004-12-27 2006-12-14 Eisai Research Institute Sustained release formulations
IL166183A0 (en) * 2005-01-06 2006-01-15 Yissum Res Dev Co Novel diagnostic and imaging techniques of the gi tract
KR100822519B1 (ko) * 2005-02-15 2008-04-16 주식회사종근당 위장 내에서 제어방출되는 단일 매트릭스 정제
EP1933811A2 (en) * 2005-09-30 2008-06-25 Alza Corporation Banded controlled release nanoparticle active agent formulation dosage forms and methods
US20070092565A1 (en) * 2005-10-25 2007-04-26 Pharmascience Inc. Gastric retention drug delivery system
TR201902010T4 (tr) 2006-01-18 2019-03-21 Intec Pharma Ltd Bir ajanın oral alımına yönelik taşıyıcı cihaz.
WO2007093999A1 (en) * 2006-02-15 2007-08-23 Intec Pharma Ltd. A gastro-retentive system for the delivery of macromolecules
WO2007103286A2 (en) * 2006-03-02 2007-09-13 Spherics, Inc. Rate-controlled bioadhesive oral dosage formulations
US20080139655A1 (en) * 2006-09-08 2008-06-12 Drugtech Corporation Sustained-release composition and method of use thereof
ZA200904573B (en) 2006-12-22 2010-09-29 Ironwood Pharmaceuticals Inc Compositions comprising bile acid sequestrants for treating esophageal disorders
WO2008115597A2 (en) * 2007-03-21 2008-09-25 Cytologic, Inc. Cytokine muteins and methods for enhancing immune responses in mammals
PT2192946T (pt) 2007-09-25 2022-11-17 Otsuka Pharma Co Ltd Dispositivo no corpo com amplificação de sinal dipolo virtual
ES2463774T3 (es) 2007-11-12 2014-05-29 Pharmaceutics International, Inc. Complejos trimoleculares y su uso en sistemas de administración de fármacos
EP2276473B1 (en) * 2008-04-18 2016-09-14 Intec Pharma Ltd. Gastroretentive drug delivery for carbidopa/levodopa
US7981760B2 (en) * 2008-05-08 2011-07-19 Panasonic Corporation Method for manufacturing nonvolatile storage element and method for manufacturing nonvolatile storage device
US8287902B2 (en) * 2008-07-23 2012-10-16 Rainbow Medical Ltd. Enhanced-diffusion capsule
WO2010064139A2 (en) * 2008-12-04 2010-06-10 Intec Pharma Ltd. Zaleplon gastroretentive drug delivery system
US9901551B2 (en) 2009-04-20 2018-02-27 Ambra Bioscience Llc Chemosensory receptor ligand-based therapies
US8828953B2 (en) * 2009-04-20 2014-09-09 NaZura BioHealth, Inc. Chemosensory receptor ligand-based therapies
JP2012524125A (ja) 2009-04-20 2012-10-11 エルセリクス セラピューティクス インコーポレイテッド 化学感覚受容体リガンドに基づく治療法
US8414559B2 (en) * 2009-05-07 2013-04-09 Rainbow Medical Ltd. Gastroretentive duodenal pill
US20100286628A1 (en) * 2009-05-07 2010-11-11 Rainbow Medical Ltd Gastric anchor
US20110066175A1 (en) * 2009-05-07 2011-03-17 Rainbow Medical Ltd. Gastric anchor
WO2011048494A2 (en) * 2009-10-19 2011-04-28 Intec Pharma Ltd. Novel gastroretentive dosage forms of poorly soluble drugs
CA2780294C (en) 2009-11-09 2018-01-16 Spotlight Technology Partners Llc Polysaccharide based hydrogels
CN107033368A (zh) 2009-11-09 2017-08-11 聚光灯技术合伙有限责任公司 碎裂水凝胶
JP5753187B2 (ja) 2009-12-18 2015-07-22 ヴィセラ・バイオメディカル・リミテッド 医用生体材料
WO2011073968A1 (en) * 2009-12-18 2011-06-23 Vysera Biomedical Limited A drug delivery system
EP2544666A2 (en) 2010-03-09 2013-01-16 Council of Scientific and Industrial Research Gastroretentive, extended release composition of therapeutic agent
US10010439B2 (en) 2010-06-13 2018-07-03 Synerz Medical, Inc. Intragastric device for treating obesity
US9526648B2 (en) 2010-06-13 2016-12-27 Synerz Medical, Inc. Intragastric device for treating obesity
US8628554B2 (en) 2010-06-13 2014-01-14 Virender K. Sharma Intragastric device for treating obesity
US10420665B2 (en) 2010-06-13 2019-09-24 W. L. Gore & Associates, Inc. Intragastric device for treating obesity
US20130156720A1 (en) 2010-08-27 2013-06-20 Ironwood Pharmaceuticals, Inc. Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
SG189444A1 (en) 2010-10-19 2013-05-31 Elcelyx Therapeutics Inc Chemosensory receptor ligand-based therapies
HRP20201731T1 (hr) 2011-01-07 2020-12-25 Anji Pharma (Us) Llc Terapije na bazi liganda kemozensoričkog receptora
US8722066B2 (en) 2011-03-29 2014-05-13 Primigenia, LLC Devices and methods for weight control and weight loss
US20130143867A1 (en) 2011-12-02 2013-06-06 Sychroneuron Inc. Acamprosate formulations, methods of using the same, and combinations comprising the same
WO2013158928A2 (en) 2012-04-18 2013-10-24 Elcelyx Therapeutics, Inc. Chemosensory receptor ligand-based therapies
WO2014039951A1 (en) 2012-09-10 2014-03-13 Novartis Ag Enteral pharmaceutical compositions
US9682081B2 (en) 2013-04-25 2017-06-20 Sun Pharmaceutical Industries Limited Pharmaceutical gastro-retentive solid oral dosage form of nilotinib
US10166207B2 (en) 2013-06-05 2019-01-01 Synchroneuron, Inc. Acamprosate formulations, methods of using the same, and combinations comprising the same
EP3083031B1 (en) * 2013-12-20 2019-10-16 Fresenius Kabi Deutschland GmbH Microcapsules with polymeric coating comprising a lipid and an active agent
CN106535878B (zh) 2014-06-02 2022-11-01 科莱西奥生物科技有限公司 可张开的胃内滞留剂型
CN106573999A (zh) 2014-06-11 2017-04-19 麻省理工学院 驻留结构及相关方法
US20170266112A1 (en) 2014-06-11 2017-09-21 Massachusetts Institute Of Technology Residence structures and related methods
US9492396B2 (en) 2014-07-15 2016-11-15 Yossi Gross Enhanced drug delivery pill
CN206120771U (zh) * 2015-06-03 2017-04-26 南京三迭纪医药科技有限公司 药品剂型
EP3302442B1 (en) * 2015-06-03 2024-10-16 Triastek, Inc. Dosage forms and use thereof
MA42196A (fr) 2015-06-17 2018-04-25 Biogen Ma Inc Particules de fumarate de diméthyle et leurs compositions pharmaceutiques
WO2017070612A1 (en) 2015-10-23 2017-04-27 Lyndra, Inc. Gastric residence systems for sustained release of therapeutic agents and methods of use thereof
US11129798B2 (en) 2016-08-19 2021-09-28 Aron H. Blaesi Fibrous dosage form
US11478427B2 (en) * 2015-10-26 2022-10-25 Aron H. Blaesi Dosage form comprising structural framework of two-dimensional elements
EP3368010B1 (en) * 2015-10-26 2025-12-10 Blaesi, Aron H. Solid dosage form immediate drug release and apparatus and method for manufacture thereof
CN108601724A (zh) * 2015-12-01 2018-09-28 克雷西奥生物科技有限公司 胃滞留装置
CA3007165A1 (en) * 2015-12-02 2017-06-08 Clexio Biosciences Ltd. Device for preparing gastroretentive dosage forms
ES2963058T3 (es) 2015-12-08 2024-03-25 Lyndra Therapeutics Inc Configuraciones geométricas para sistemas de residencia gástrica
CA3017797A1 (en) 2016-03-17 2017-09-21 Thiogenesis Therapeutics, Inc. Compositions for controlled release of cysteamine and systemic treatment of cysteamine sensitive disorders
US10779980B2 (en) 2016-04-27 2020-09-22 Synerz Medical, Inc. Intragastric device for treating obesity
US12109305B2 (en) 2016-05-27 2024-10-08 Lyndra Therapeutics, Inc. Materials architecture for gastric residence systems
SG11201811209QA (en) * 2016-07-11 2019-01-30 Intec Pharma Ltd Oral gastroretentive formulations and uses thereof
WO2018064630A1 (en) 2016-09-30 2018-04-05 Lyndra, Inc. Gastric residence systems for sustained delivery of adamantane-class drugs
CN110035718B (zh) 2016-12-02 2021-04-06 克雷西奥生物科技有限公司 胃内滞留系统
WO2018137686A1 (en) 2017-01-26 2018-08-02 Triastek, Inc. Dosage forms of controlled release at specific gastrointestinal sites
US12023406B2 (en) 2017-06-09 2024-07-02 Lyndra Therapeutics, Inc. Gastric residence systems with release rate-modulating films
ES3024932T3 (en) 2017-09-20 2025-06-05 Thiogenesis Therapeutics Inc Compounds for the treatment of cysteamine sensitive disorders
US11547839B2 (en) 2017-12-04 2023-01-10 Clexio Biosciences Ltd. Long acting gastric residence system
CN116270513A (zh) 2018-01-09 2023-06-23 南京三迭纪医药科技有限公司 一种包含固定剂量adhd非兴奋剂和adhd兴奋剂的复方口服药物剂型
CN114191307A (zh) 2020-09-17 2022-03-18 上海汉都医药科技有限公司 一种口腔滞留装置及其制备方法
WO2019223753A1 (zh) 2018-05-23 2019-11-28 上海汉都医药科技有限公司 活性药物成分的控释系统及其制备方法
US11911513B2 (en) 2018-05-23 2024-02-27 Shanghai Wd Pharmaceutical Co., Ltd Controlled-release system of active pharmaceutical ingredient and preparation method therefor
US10675248B2 (en) 2018-08-14 2020-06-09 Alma Therapeutics Ltd. Expandable pill
EP4477215A3 (en) 2020-12-08 2025-02-19 Ruminant Biotech Corp Limited Improvements to devices and methods for delivery of substances to animals
WO2022245913A1 (en) 2021-05-20 2022-11-24 E Ink California, Llc Benefit agent delivery system using electroplating

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3574820A (en) 1968-01-08 1971-04-13 Upjohn Co Medicinal dosage forms of unpolymerized thiolated gelatin with a cross-linking accelerating agent providing slowly released medication from a swollen matrix
US4207890A (en) 1977-01-04 1980-06-17 Mcneilab, Inc. Drug-dispensing device and method
US4434153A (en) 1982-03-22 1984-02-28 Alza Corporation Drug delivery system comprising a reservoir containing a plurality of tiny pills
US4735804A (en) 1985-05-10 1988-04-05 Merck & Co., Inc. Drug delivery device which can be retained in the stomach for a controlled period of time
US4758436A (en) 1985-05-29 1988-07-19 Merck & Co., Inc. Drug delivery device which can be retained in the stomach for a controlled period of time
US4767627A (en) 1985-05-29 1988-08-30 Merck & Co., Inc. Drug delivery device which can be retained in the stomach for a controlled period of time
US5002772A (en) 1988-05-31 1991-03-26 Pfizer Inc. Gastric retention system for controlled drug release
US5217712A (en) 1989-09-20 1993-06-08 Merck & Co., Inc. Bioerodible thermoset elastomers
US5047464A (en) 1989-09-20 1991-09-10 Merck & Co., Inc. Bioerodible thermoset elastomers
IT1265240B1 (it) * 1993-11-30 1996-10-31 Ekita Investments Nv Compressa farmaceutica a rilascio controllato, di forma lenticolare
DE4406424A1 (de) 1994-02-28 1995-08-31 Bayer Ag Expandierbare Arzneiformen
US5840332A (en) * 1996-01-18 1998-11-24 Perio Products Ltd. Gastrointestinal drug delivery system

Also Published As

Publication number Publication date
AU783062B2 (en) 2005-09-22
RU2002114348A (ru) 2004-01-10
US6685962B2 (en) 2004-02-03
JP2003514845A (ja) 2003-04-22
IL149853A (en) 2006-12-31
EP1235557A2 (en) 2002-09-04
US20030021845A1 (en) 2003-01-30
ES2243327T3 (es) 2005-12-01
DE60021604D1 (de) 2005-09-01
WO2001037812A3 (en) 2002-02-21
WO2001037812A2 (en) 2001-05-31
IL133196A0 (en) 2001-03-19
ATE300286T1 (de) 2005-08-15
CA2392361A1 (en) 2001-05-31
JP4679020B2 (ja) 2011-04-27
AU1647701A (en) 2001-06-04
EP1235557B1 (en) 2005-07-27
CA2392361C (en) 2010-01-19
DE60021604T2 (de) 2006-06-01

Similar Documents

Publication Publication Date Title
IL133196A0 (en) Gastroretentive controlled release pharmaceutical dosage forms
Debotton et al. Applications of polymers as pharmaceutical excipients in solid oral dosage forms
US6632451B2 (en) Delayed total release two pulse gastrointestinal drug delivery system
US6531152B1 (en) Immediate release gastrointestinal drug delivery system
CA2446712C (en) System for osmotic delivery of pharmaceutically active agents
CA2014451A1 (en) Sustained-release oral drug dosage form
SG46584A1 (en) Controlled release drug formulation
ATE477795T1 (de) Magenretentionssystem mit kontrollierter arzneimittelfreisetzung
AU1488295A (en) Pharmaceutical composition
HRP20161433T1 (hr) Doprema lijeka zadržavanjem u želucu za karbidopa/levodopa
NZ503820A (en) A delayed followed by immediate release drug delivery system containing a core and a coating
CA2272586A1 (en) Rapidly disintegrable pharmaceutical composition
BG102438A (en) Medicamentous form
MXPA02007254A (es) Forma de dosis de cubierta-y-nucleo que se aproxima a liberacion de droga de orden cero.
WO2003051304A3 (en) Bioadhesive drug delivery system with enhanced gastric retention
EP2033648A3 (en) Sustained release drug delivery system containing prodrugs
DE69729950D1 (de) System zur verzögerten freisetzung säurelabiler substanzen
AU2002303897A1 (en) System for osmotic delivery of pharmaceutically active agents
MY130332A (en) Pharmaceutical formulation comprising iota-carrageenan and at least one neutral gelling polymer
JPH0624959A (ja) 胃内浮遊型薬物徐放性固形製剤
CA2219777A1 (en) Nanoparticles for oral administration of pharmaceutical agents of low solubility
Park et al. Polymers in pharmaceutical products
Collette et al. Triblock Copolymers Self-Assembled in Vesicles: Applications to the Oral Delivery of Insulin
EP0375649A3 (en) Swelling-controlled oral delivery system for drugs
TH57760A3 (th) การลำเลียงแบบเอนเทอริกและโคโลนิก โดยใช้แคปซูลชนิด hpmc