ZA200200462B - Biodegradable poly (alkylene oxide)-poly (p-dioxanone) block copolymer soluble in organic solvents, and drug delivery composition comprising same. - Google Patents
Biodegradable poly (alkylene oxide)-poly (p-dioxanone) block copolymer soluble in organic solvents, and drug delivery composition comprising same. Download PDFInfo
- Publication number
- ZA200200462B ZA200200462B ZA200200462A ZA200200462A ZA200200462B ZA 200200462 B ZA200200462 B ZA 200200462B ZA 200200462 A ZA200200462 A ZA 200200462A ZA 200200462 A ZA200200462 A ZA 200200462A ZA 200200462 B ZA200200462 B ZA 200200462B
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- ZA
- South Africa
- Prior art keywords
- poly
- block copolymer
- copolymer
- block
- dioxanone
- Prior art date
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- 229920001400 block copolymer Polymers 0.000 title claims abstract description 53
- 239000000203 mixture Substances 0.000 title claims abstract description 33
- 229920002463 poly(p-dioxanone) polymer Polymers 0.000 title claims abstract description 14
- 239000003960 organic solvent Substances 0.000 title claims abstract description 12
- 238000012377 drug delivery Methods 0.000 title abstract description 11
- 125000002947 alkylene group Chemical group 0.000 title description 2
- -1 poly(p-dioxanone) Polymers 0.000 claims abstract description 68
- 229920000233 poly(alkylene oxides) Polymers 0.000 claims abstract description 16
- 229920001577 copolymer Polymers 0.000 claims description 34
- VPVXHAANQNHFSF-UHFFFAOYSA-N 1,4-dioxan-2-one Chemical compound O=C1COCCO1 VPVXHAANQNHFSF-UHFFFAOYSA-N 0.000 claims description 24
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
- A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/66—Polyesters containing oxygen in the form of ether groups
- C08G63/664—Polyesters containing oxygen in the form of ether groups derived from hydroxy carboxylic acids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/906—Drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Dispersion Chemistry (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Physics & Mathematics (AREA)
- Polymers & Plastics (AREA)
- Nanotechnology (AREA)
- Optics & Photonics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
- Polyesters Or Polycarbonates (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1019990029269A KR20010010393A (ko) | 1999-07-20 | 1999-07-20 | 소수성 고분자와 친수성 고분자의 생분해성 블록 공중합체 및이를 포함하는 약물 전달체 조성물 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200200462B true ZA200200462B (en) | 2003-03-26 |
Family
ID=19602907
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200200462A ZA200200462B (en) | 1999-07-20 | 2002-01-18 | Biodegradable poly (alkylene oxide)-poly (p-dioxanone) block copolymer soluble in organic solvents, and drug delivery composition comprising same. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US6599519B1 (es) |
| EP (1) | EP1196149B1 (es) |
| JP (1) | JP3955759B2 (es) |
| KR (2) | KR20010010393A (es) |
| CN (1) | CN1205248C (es) |
| AT (1) | ATE468848T1 (es) |
| AU (1) | AU758838B2 (es) |
| BR (1) | BRPI0012588B8 (es) |
| CA (1) | CA2379672C (es) |
| DE (1) | DE60044459D1 (es) |
| MX (1) | MXPA02000600A (es) |
| NZ (1) | NZ517035A (es) |
| WO (1) | WO2001005379A1 (es) |
| ZA (1) | ZA200200462B (es) |
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| BR112020001832A2 (pt) * | 2017-08-11 | 2020-07-28 | Ferring B.V. | método de produção de uma composição farmacêuti-ca |
| KR102013041B1 (ko) | 2017-12-21 | 2019-08-21 | 포항공과대학교 산학협력단 | 항암제가 담지된 나노구조체를 유효성분으로 포함하는 간암 치료용 약학조성물 |
| KR102093660B1 (ko) * | 2019-07-08 | 2020-03-26 | (주)리젠바이오참 | 온도감응형 조직유착 방지용 하이드로겔 조성물 및 그 제조방법 |
| CA3165573A1 (en) | 2019-12-22 | 2021-07-01 | Sweetwater Energy, Inc. | Methods of making specialized lignin and lignin products from biomass |
| KR102365597B1 (ko) * | 2019-12-24 | 2022-02-18 | 성균관대학교산학협력단 | 에멀젼 조성물, 그리고 이를 포함하는 약물 조성물 및 화장품용 조성물 |
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| US4643191A (en) | 1985-11-29 | 1987-02-17 | Ethicon, Inc. | Crystalline copolymers of p-dioxanone and lactide and surgical devices made therefrom |
| US5019094A (en) * | 1990-05-09 | 1991-05-28 | Ethicon, Inc. | Crystalline copolymers of p-dioxanone and poly(alkylene oxides) |
| US5080665A (en) | 1990-07-06 | 1992-01-14 | American Cyanamid Company | Deformable, absorbable surgical device |
| US5352515A (en) * | 1992-03-02 | 1994-10-04 | American Cyanamid Company | Coating for tissue drag reduction |
| US5522841A (en) * | 1993-05-27 | 1996-06-04 | United States Surgical Corporation | Absorbable block copolymers and surgical articles fabricated therefrom |
-
1999
- 1999-07-20 KR KR1019990029269A patent/KR20010010393A/ko active Search and Examination
-
2000
- 2000-07-18 KR KR10-2001-7001936A patent/KR100431491B1/ko active IP Right Grant
- 2000-07-18 CA CA002379672A patent/CA2379672C/en not_active Expired - Lifetime
- 2000-07-18 MX MXPA02000600A patent/MXPA02000600A/es active IP Right Grant
- 2000-07-18 US US09/763,921 patent/US6599519B1/en not_active Expired - Lifetime
- 2000-07-18 BR BRPI0012588A patent/BRPI0012588B8/pt not_active IP Right Cessation
- 2000-07-18 EP EP00946497A patent/EP1196149B1/en not_active Expired - Lifetime
- 2000-07-18 WO PCT/KR2000/000779 patent/WO2001005379A1/en active IP Right Grant
- 2000-07-18 JP JP2001510436A patent/JP3955759B2/ja not_active Expired - Fee Related
- 2000-07-18 NZ NZ517035A patent/NZ517035A/en not_active IP Right Cessation
- 2000-07-18 AU AU60247/00A patent/AU758838B2/en not_active Expired
- 2000-07-18 DE DE60044459T patent/DE60044459D1/de not_active Expired - Lifetime
- 2000-07-18 CN CNB008105375A patent/CN1205248C/zh not_active Expired - Lifetime
- 2000-07-18 AT AT00946497T patent/ATE468848T1/de not_active IP Right Cessation
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2002
- 2002-01-18 ZA ZA200200462A patent/ZA200200462B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1361684A (zh) | 2002-07-31 |
| CN1205248C (zh) | 2005-06-08 |
| KR100431491B1 (ko) | 2004-05-14 |
| US6599519B1 (en) | 2003-07-29 |
| NZ517035A (en) | 2003-07-25 |
| EP1196149A1 (en) | 2002-04-17 |
| MXPA02000600A (es) | 2002-07-02 |
| AU758838B2 (en) | 2003-04-03 |
| KR20020008815A (ko) | 2002-01-31 |
| AU6024700A (en) | 2001-02-05 |
| EP1196149A4 (en) | 2004-04-21 |
| WO2001005379A1 (en) | 2001-01-25 |
| JP2003504393A (ja) | 2003-02-04 |
| JP3955759B2 (ja) | 2007-08-08 |
| BR0012588A (pt) | 2002-04-09 |
| CA2379672A1 (en) | 2001-01-25 |
| DE60044459D1 (de) | 2010-07-08 |
| BRPI0012588B8 (pt) | 2021-05-25 |
| KR20010010393A (ko) | 2001-02-05 |
| CA2379672C (en) | 2005-03-22 |
| BR0012588B1 (pt) | 2013-02-19 |
| ATE468848T1 (de) | 2010-06-15 |
| EP1196149B1 (en) | 2010-05-26 |
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