ZA200200298B - C-Pyrazole A2A receptor agonists. - Google Patents

C-Pyrazole A2A receptor agonists.

Info

Publication number
ZA200200298B
ZA200200298B ZA200200298A ZA200200298A ZA200200298B ZA 200200298 B ZA200200298 B ZA 200200298B ZA 200200298 A ZA200200298 A ZA 200200298A ZA 200200298 A ZA200200298 A ZA 200200298A ZA 200200298 B ZA200200298 B ZA 200200298B
Authority
ZA
South Africa
Prior art keywords
pyrazole
receptor agonists
agonists
receptor
Prior art date
Application number
ZA200200298A
Other languages
English (en)
Inventor
Jeffrey A Zablocki
Elfatih O Elzein
Venkata P Palle
Original Assignee
Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Therapeutics Inc filed Critical Therapeutics Inc
Publication of ZA200200298B publication Critical patent/ZA200200298B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Genetics & Genomics (AREA)
  • Cardiology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA200200298A 1999-06-22 2002-01-14 C-Pyrazole A2A receptor agonists. ZA200200298B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/338,327 US6214807B1 (en) 1999-06-22 1999-06-22 C-pyrazole 2A A receptor agonists

Publications (1)

Publication Number Publication Date
ZA200200298B true ZA200200298B (en) 2003-04-30

Family

ID=23324355

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200200298A ZA200200298B (en) 1999-06-22 2002-01-14 C-Pyrazole A2A receptor agonists.

Country Status (23)

Country Link
US (6) US6214807B1 (https=)
EP (1) EP1192169B1 (https=)
JP (1) JP4795591B2 (https=)
KR (1) KR100511733B1 (https=)
CN (1) CN1152041C (https=)
AR (1) AR033794A1 (https=)
AT (1) ATE240341T1 (https=)
AU (1) AU766712B2 (https=)
BR (1) BR0011854A (https=)
CA (1) CA2375430C (https=)
DE (1) DE60002722T2 (https=)
DK (1) DK1192169T3 (https=)
ES (1) ES2193969T3 (https=)
HK (1) HK1044953A1 (https=)
IL (2) IL147195A0 (https=)
MX (1) MXPA01013350A (https=)
NO (1) NO323163B1 (https=)
NZ (1) NZ516335A (https=)
PT (1) PT1192169E (https=)
TR (1) TR200200320T2 (https=)
TW (1) TW589321B (https=)
WO (1) WO2000078778A2 (https=)
ZA (1) ZA200200298B (https=)

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GB0500785D0 (en) * 2005-01-14 2005-02-23 Novartis Ag Organic compounds
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GB0607950D0 (en) * 2006-04-21 2006-05-31 Novartis Ag Organic compounds
PT2322525E (pt) * 2006-04-21 2013-12-26 Novartis Ag Derivados de purina para utilização como agonistas do recetor de adenosina a2a
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EA201290958A1 (ru) 2010-03-26 2013-04-30 Инотек Фармасьютикалз Корпорейшн Способ снижения внутриглазного давления у людей с применением n6-циклопентиладенозина (cpa), производных cpa или их пролекарств
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Also Published As

Publication number Publication date
NO20016351L (no) 2002-02-18
AR033794A1 (es) 2004-01-07
KR100511733B1 (ko) 2005-08-31
DK1192169T3 (da) 2003-08-04
US6214807B1 (en) 2001-04-10
US7109180B2 (en) 2006-09-19
NO323163B1 (no) 2007-01-08
EP1192169B1 (en) 2003-05-14
CN1152041C (zh) 2004-06-02
MXPA01013350A (es) 2002-07-09
CA2375430C (en) 2006-03-14
HK1044953A1 (zh) 2002-11-08
TW589321B (en) 2004-06-01
JP4795591B2 (ja) 2011-10-19
WO2000078778A3 (en) 2001-05-10
ES2193969T3 (es) 2003-11-16
US20040198692A1 (en) 2004-10-07
AU766712B2 (en) 2003-10-23
DE60002722D1 (de) 2003-06-18
NO20016351D0 (no) 2001-12-21
US20100081810A1 (en) 2010-04-01
EP1192169A2 (en) 2002-04-03
US7553823B2 (en) 2009-06-30
PT1192169E (pt) 2003-09-30
US6770634B1 (en) 2004-08-03
CN1358189A (zh) 2002-07-10
AU5755800A (en) 2001-01-09
IL147195A (en) 2007-10-31
CA2375430A1 (en) 2000-12-28
ATE240341T1 (de) 2003-05-15
KR20020028911A (ko) 2002-04-17
US6855818B2 (en) 2005-02-15
US20010018428A1 (en) 2001-08-30
IL147195A0 (en) 2002-08-14
DE60002722T2 (de) 2004-04-08
JP2003506460A (ja) 2003-02-18
BR0011854A (pt) 2002-06-11
NZ516335A (en) 2003-10-31
WO2000078778A2 (en) 2000-12-28
US20070207978A1 (en) 2007-09-06
TR200200320T2 (tr) 2002-05-21

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