KR100511733B1 - Ｃ-피라졸 ａ2ａ 수용체 작용제 - Google Patents

Ｃ-피라졸 ａ2ａ 수용체 작용제 Download PDF

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Publication number
KR100511733B1
KR100511733B1 KR10-2001-7016496A KR20017016496A KR100511733B1 KR 100511733 B1 KR100511733 B1 KR 100511733B1 KR 20017016496 A KR20017016496 A KR 20017016496A KR 100511733 B1 KR100511733 B1 KR 100511733B1
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KR
South Korea
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alkyl
aryl
substituted
group
unsubstituted
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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KR10-2001-7016496A
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English (en)
Korean (ko)
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KR20020028911A (ko
Inventor
제프 에이. 자블로키
엘퍼티 오. 엘제인
벤카타 피. 팔레
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씨브이 쎄러퓨틱스, 인코포레이티드
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Publication of KR20020028911A publication Critical patent/KR20020028911A/ko
Application granted granted Critical
Publication of KR100511733B1 publication Critical patent/KR100511733B1/ko
Assigned to 길리애드 사이언시즈, 인코포레이티드 reassignment 길리애드 사이언시즈, 인코포레이티드 권리의 전부이전등록 Assignors: 질레드 팔로 알토 인코포레이티드
Assigned to 질레드 팔로 알토 인코포레이티드 reassignment 질레드 팔로 알토 인코포레이티드 권리의 전부이전등록 Assignors: 씨브이 쎄러퓨틱스, 인코포레이티드
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Genetics & Genomics (AREA)
  • Cardiology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
KR10-2001-7016496A 1999-06-22 2000-06-21 Ｃ-피라졸 ａ2ａ 수용체 작용제 Expired - Lifetime KR100511733B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/338,327 US6214807B1 (en) 1999-06-22 1999-06-22 C-pyrazole 2A A receptor agonists
US09/338,327 1999-06-22

Publications (2)

Publication Number Publication Date
KR20020028911A KR20020028911A (ko) 2002-04-17
KR100511733B1 true KR100511733B1 (ko) 2005-08-31

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
KR10-2001-7016496A Expired - Lifetime KR100511733B1 (ko) 1999-06-22 2000-06-21 Ｃ-피라졸 ａ2ａ 수용체 작용제

Country Status (23)

Country Link
US (6) US6214807B1 (https=)
EP (1) EP1192169B1 (https=)
JP (1) JP4795591B2 (https=)
KR (1) KR100511733B1 (https=)
CN (1) CN1152041C (https=)
AR (1) AR033794A1 (https=)
AT (1) ATE240341T1 (https=)
AU (1) AU766712B2 (https=)
BR (1) BR0011854A (https=)
CA (1) CA2375430C (https=)
DE (1) DE60002722T2 (https=)
DK (1) DK1192169T3 (https=)
ES (1) ES2193969T3 (https=)
HK (1) HK1044953A1 (https=)
IL (2) IL147195A0 (https=)
MX (1) MXPA01013350A (https=)
NO (1) NO323163B1 (https=)
NZ (1) NZ516335A (https=)
PT (1) PT1192169E (https=)
TR (1) TR200200320T2 (https=)
TW (1) TW589321B (https=)
WO (1) WO2000078778A2 (https=)
ZA (1) ZA200200298B (https=)

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Publication number Publication date
NO20016351L (no) 2002-02-18
AR033794A1 (es) 2004-01-07
DK1192169T3 (da) 2003-08-04
US6214807B1 (en) 2001-04-10
US7109180B2 (en) 2006-09-19
NO323163B1 (no) 2007-01-08
EP1192169B1 (en) 2003-05-14
CN1152041C (zh) 2004-06-02
MXPA01013350A (es) 2002-07-09
CA2375430C (en) 2006-03-14
HK1044953A1 (zh) 2002-11-08
TW589321B (en) 2004-06-01
JP4795591B2 (ja) 2011-10-19
WO2000078778A3 (en) 2001-05-10
ZA200200298B (en) 2003-04-30
ES2193969T3 (es) 2003-11-16
US20040198692A1 (en) 2004-10-07
AU766712B2 (en) 2003-10-23
DE60002722D1 (de) 2003-06-18
NO20016351D0 (no) 2001-12-21
US20100081810A1 (en) 2010-04-01
EP1192169A2 (en) 2002-04-03
US7553823B2 (en) 2009-06-30
PT1192169E (pt) 2003-09-30
US6770634B1 (en) 2004-08-03
CN1358189A (zh) 2002-07-10
AU5755800A (en) 2001-01-09
IL147195A (en) 2007-10-31
CA2375430A1 (en) 2000-12-28
ATE240341T1 (de) 2003-05-15
KR20020028911A (ko) 2002-04-17
US6855818B2 (en) 2005-02-15
US20010018428A1 (en) 2001-08-30
IL147195A0 (en) 2002-08-14
DE60002722T2 (de) 2004-04-08
JP2003506460A (ja) 2003-02-18
BR0011854A (pt) 2002-06-11
NZ516335A (en) 2003-10-31
WO2000078778A2 (en) 2000-12-28
US20070207978A1 (en) 2007-09-06
TR200200320T2 (tr) 2002-05-21

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