ZA200109862B - Amorphous nitric esters and their pharmaceutical compositions. - Google Patents

Amorphous nitric esters and their pharmaceutical compositions.

Info

Publication number
ZA200109862B
ZA200109862B ZA200109862A ZA200109862A ZA200109862B ZA 200109862 B ZA200109862 B ZA 200109862B ZA 200109862 A ZA200109862 A ZA 200109862A ZA 200109862 A ZA200109862 A ZA 200109862A ZA 200109862 B ZA200109862 B ZA 200109862B
Authority
ZA
South Africa
Prior art keywords
pharmaceutical compositions
nitric esters
amorphous
amorphous nitric
esters
Prior art date
Application number
ZA200109862A
Other languages
English (en)
Inventor
Francesca Benedini
Patrizia Antognazza
Original Assignee
Nicox Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nicox Sa filed Critical Nicox Sa
Publication of ZA200109862B publication Critical patent/ZA200109862B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C203/00—Esters of nitric or nitrous acid
    • C07C203/02—Esters of nitric acid
    • C07C203/04—Esters of nitric acid having nitrate groups bound to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ZA200109862A 1999-06-24 2001-11-29 Amorphous nitric esters and their pharmaceutical compositions. ZA200109862B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1999MI001402A IT1312115B1 (it) 1999-06-24 1999-06-24 Composti amorfi e relative composizioni farmaceutiche

Publications (1)

Publication Number Publication Date
ZA200109862B true ZA200109862B (en) 2003-05-28

Family

ID=11383219

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200109862A ZA200109862B (en) 1999-06-24 2001-11-29 Amorphous nitric esters and their pharmaceutical compositions.

Country Status (23)

Country Link
US (1) US6753442B1 (no)
EP (1) EP1187803B1 (no)
JP (1) JP2003503380A (no)
KR (1) KR100672001B1 (no)
CN (1) CN1187312C (no)
AT (1) ATE302746T1 (no)
AU (1) AU781479B2 (no)
BR (1) BR0011831A (no)
CA (1) CA2377132A1 (no)
DE (1) DE60022188T2 (no)
DK (1) DK1187803T3 (no)
ES (1) ES2246878T3 (no)
HU (1) HUP0201721A3 (no)
IL (1) IL146789A0 (no)
IT (1) IT1312115B1 (no)
MX (1) MXPA01013273A (no)
NO (1) NO321523B1 (no)
NZ (1) NZ515757A (no)
PL (1) PL195557B1 (no)
RU (1) RU2248963C2 (no)
TR (1) TR200103624T2 (no)
WO (1) WO2001000563A1 (no)
ZA (1) ZA200109862B (no)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1319202B1 (it) * 2000-10-12 2003-09-26 Nicox Sa Farmaci per le malattie a base infiammatoria.
DE60122939T2 (de) 2000-12-21 2007-01-11 Nitromed, Inc., Bedford Substituierte arylverbindungen als neue, cyclooxygenase-2-selektive inhibitoren, zusammensetzungen und verwendungsverfahren
EP1219306A1 (en) * 2000-12-29 2002-07-03 Nicox S.A. Compositions comprising cyclodextrins and NO- releasing drugs
AU2003248642A1 (en) 2002-06-11 2003-12-22 Nitromed, Inc. Nitrosated and/or nitrosylated cyclooxygenase-2 selective inhibitors, compositions and methods of use
CA2491127A1 (en) 2002-07-03 2004-01-15 Nitromed, Inc. Nitrosated nonsteroidal antiinflammatory compounds, compositions and methods of use
CA2493156A1 (en) 2002-07-29 2004-02-05 Nitromed, Inc. Cyclooxygenase-2 selective inhibitors, compositions and methods of use
US8754238B2 (en) 2003-07-22 2014-06-17 Arena Pharmaceuticals, Inc. Diaryl and arylheteroaryl urea derivatives as modulators of the 5-HT2A serotonin receptor useful for the prophylaxis and treatment of disorders related thereto
TWI415845B (zh) 2006-10-03 2013-11-21 Arena Pharm Inc 用於治療與５-ｈｔ2ａ血清素受體相關聯病症之作為５-ｈｔ2ａ血清素受體之調節劑的吡唑衍生物
EP2190844B3 (en) 2007-08-15 2013-07-17 Arena Pharmaceuticals, Inc. Imidazo[1,2-a]pyridine derivatives as modulators of the 5-ht2a serotonin receptor useful for the treatment of disorders related thereto
CA2702909C (en) * 2007-10-17 2016-05-10 Todd F. Ovokaitys Room temperature stable non-crystalline aspirin
WO2009052246A1 (en) * 2007-10-17 2009-04-23 Ovokaitys, Todd, F. Process for the modification of the solid state of a compound and co-amorphous compositions produced with same
ES2324007A1 (es) * 2007-10-25 2009-07-28 Ferrer Internacional, S.A. Una forma amorfa de un compuesto antiinflamatorio.
US20110021538A1 (en) 2008-04-02 2011-01-27 Arena Pharmaceuticals, Inc. Processes for the preparation of pyrazole derivatives useful as modulators of the 5-ht2a serotonin receptor
CA2741731A1 (en) 2008-10-28 2010-06-03 Arena Pharmaceuticals, Inc. Compositions of a 5-ht2a serotonin receptor modulator useful for the treatment of disorders related thereto
US9126946B2 (en) 2008-10-28 2015-09-08 Arena Pharmaceuticals, Inc. Processes useful for the preparation of 1-[3-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)urea and crystalline forms related thereto
WO2010053532A2 (en) 2008-11-04 2010-05-14 Dsm Ip Assets B.V. D 1413 ht radiation curable coatings for optical fiber
US10202598B2 (en) 2014-05-30 2019-02-12 Todd Frank Ovokaitys Methods and systems for generation, use, and delivery of activated stem cells
WO2015187974A1 (en) 2014-06-06 2015-12-10 Ovokaitys Todd Frank Methods and compositions for increasing the bioactivity of nutrients
US10384985B2 (en) 2014-06-06 2019-08-20 B.K. Consultants, Inc. Methods and compositions for increasing the yield of, and beneficial chemical composition of, certain plants
KR20180022792A (ko) 2015-06-12 2018-03-06 엑소반트 사이언시즈 게엠베하 렘 수면 행동 장애의 예방 및 치료에 유용한 디아릴 및 아릴헤테로아릴 우레아 유도체
BR112018000728A2 (pt) 2015-07-15 2018-09-04 Axovant Sciences Gmbh resumo método para a profilaxia e/ou tratamento de alucinações visuais em um sujeito com necessidade do mesmo

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1243367B (it) * 1990-07-26 1994-06-10 Italfarmaco Spa Derivati acidi benzoici sostituiti ad attivita' cardiovascolare
IT1256345B (it) * 1992-08-20 1995-12-01 Esteri nitrici di derivati dell'acido 2-(2,6-di-alo-fenilammino) fenilacetico e procedimento per la loro preparazione
IT1256450B (it) * 1992-11-26 1995-12-05 Soldato Piero Del Esteri nitrici con attivita' farmacologica e procedimento per la loro preparazione
DK0759899T3 (da) * 1994-05-10 1999-12-20 Nicox Sa Nitroforbindelser og sammensætninger deraf med antiinflammatoriske, analgetiske og antitrombotiske aktiviteter
IT1276071B1 (it) * 1995-10-31 1997-10-24 Nicox Ltd Compositi ad attivita' anti-infiammatoria
KR19990001564A (ko) * 1997-06-16 1999-01-15 유충식 용해도를 개선한 아졸계 항진균제 및 이를 함유하는 제제
IT1307928B1 (it) 1999-01-26 2001-11-29 Nicox Sa Metodo di sintesi di nitrossimetilfenil esteri di derivatidell'aspirina.

Also Published As

Publication number Publication date
HUP0201721A3 (en) 2003-08-28
ES2246878T3 (es) 2006-03-01
NZ515757A (en) 2004-02-27
TR200103624T2 (tr) 2002-04-22
CN1356975A (zh) 2002-07-03
PL352529A1 (en) 2003-08-25
CN1187312C (zh) 2005-02-02
KR100672001B1 (ko) 2007-01-19
ITMI991402A0 (it) 1999-06-24
NO20016232D0 (no) 2001-12-19
DE60022188T2 (de) 2006-06-08
ITMI991402A1 (it) 2000-12-24
EP1187803A1 (en) 2002-03-20
EP1187803B1 (en) 2005-08-24
PL195557B1 (pl) 2007-10-31
RU2248963C2 (ru) 2005-03-27
KR20020008220A (ko) 2002-01-29
DK1187803T3 (da) 2005-11-28
AU781479B2 (en) 2005-05-26
HUP0201721A2 (en) 2002-10-28
JP2003503380A (ja) 2003-01-28
US6753442B1 (en) 2004-06-22
CA2377132A1 (en) 2001-01-04
DE60022188D1 (de) 2005-09-29
NO20016232L (no) 2001-12-19
ATE302746T1 (de) 2005-09-15
NO321523B1 (no) 2006-05-15
AU6264400A (en) 2001-01-31
IT1312115B1 (it) 2002-04-04
IL146789A0 (en) 2002-07-25
WO2001000563A1 (en) 2001-01-04
MXPA01013273A (es) 2003-07-14
BR0011831A (pt) 2002-03-19

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