ZA200004624B - Process for the cis-selective catalytic hydrogenation of cyclohexylidenamines. - Google Patents

Process for the cis-selective catalytic hydrogenation of cyclohexylidenamines.

Info

Publication number
ZA200004624B
ZA200004624B ZA200004624A ZA200004624A ZA200004624B ZA 200004624 B ZA200004624 B ZA 200004624B ZA 200004624 A ZA200004624 A ZA 200004624A ZA 200004624 A ZA200004624 A ZA 200004624A ZA 200004624 B ZA200004624 B ZA 200004624B
Authority
ZA
South Africa
Prior art keywords
cyclohexylidenamines
cis
catalytic hydrogenation
selective catalytic
selective
Prior art date
Application number
ZA200004624A
Other languages
English (en)
Inventor
Heinz Steiner
Markus Benz
Hans-Peter Jalett
Marc Thommen
Original Assignee
Ciba Sc Holding Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Sc Holding Ag filed Critical Ciba Sc Holding Ag
Publication of ZA200004624B publication Critical patent/ZA200004624B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/44—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers
    • C07C209/52—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers by reduction of imines or imino-ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/09—Geometrical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
ZA200004624A 1998-03-18 2000-09-04 Process for the cis-selective catalytic hydrogenation of cyclohexylidenamines. ZA200004624B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH64598 1998-03-18

Publications (1)

Publication Number Publication Date
ZA200004624B true ZA200004624B (en) 2001-11-29

Family

ID=4191841

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200004624A ZA200004624B (en) 1998-03-18 2000-09-04 Process for the cis-selective catalytic hydrogenation of cyclohexylidenamines.

Country Status (16)

Country Link
US (1) US6232501B1 (https=)
EP (1) EP1064250B1 (https=)
JP (1) JP2002506844A (https=)
CN (1) CN1216033C (https=)
AR (1) AR018164A1 (https=)
AU (1) AU759530B2 (https=)
CA (1) CA2323629A1 (https=)
DE (1) DE69916593T2 (https=)
ES (1) ES2217748T3 (https=)
HU (1) HUP0101322A3 (https=)
IL (2) IL138172A0 (https=)
PT (1) PT1064250E (https=)
TR (1) TR200002673T2 (https=)
TW (1) TWI220427B (https=)
WO (1) WO1999047486A1 (https=)
ZA (1) ZA200004624B (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6500987B1 (en) 1998-11-27 2002-12-31 Teva Pharmaceutical Industries Ltd. Sertraline hydrochloride polymorphs
ATE264831T1 (de) 1999-07-29 2004-05-15 Ciba Sc Holding Ag Verfahren zur cis-selektiven katalytischen hydrierung von cyclohexylidenaminen
US6495721B1 (en) 1999-08-09 2002-12-17 Teva Pharmaceutical Industries Ltd. Sertraline hydrochloride Form II and methods for the preparation thereof
TWI260315B (en) 1999-10-29 2006-08-21 Ciba Sc Holding Ag Polymorphic forms of sertraline hydrochloride
US7442838B2 (en) 1999-10-29 2008-10-28 Ciba Specialty Chemicals Corp. Polymorphic forms of sertraline hydrochloride
EP1230211B1 (en) 1999-11-16 2005-07-20 Ciba SC Holding AG Process for the preparation of ketimines
ATE295349T1 (de) * 1999-11-16 2005-05-15 Ciba Sc Holding Ag Verfahren zur herstellung von ketiminen
ES2281374T3 (es) 1999-12-21 2007-10-01 Teva Pharmaceutical Industries Ltd. Nuevos polimorfos de hidrocloruro de sertralina, procedimientos para su preparacion, composiciones que los contienen y metodos para su utilizacion.
CZ20023269A3 (cs) * 2000-03-14 2003-09-17 Teva Pharmaceutical Industries Ltd. Způsob přípravy (+) -cis-sertralinu
US6723878B2 (en) 2001-06-15 2004-04-20 Orion Corporation Fermion Method for preparing sertraline
AU2003251290A1 (en) 2002-04-29 2003-11-17 Teva Pharmaceutical Industries Ltd. Process for preparation of polymorphic form ii of sertraline hydrochloride, pharmaceutical formulations and methods of administration thereof
ES2242555T1 (es) * 2003-04-14 2005-11-16 Teva Pharmaceutical Industries Limited Hidrogenacion de intermediarios de imina de sertralina con catalizadores.
WO2006129324A2 (en) 2005-06-03 2006-12-07 Hetero Drugs Limited A highly stereoselective synthesis of sertraline
US8354558B2 (en) * 2007-12-21 2013-01-15 Basf Se Process for diastereoselective conversion of chiral imines
US8415500B2 (en) * 2007-12-21 2013-04-09 Basf Se One-stage reductive amination

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4536518A (en) * 1979-11-01 1985-08-20 Pfizer Inc. Antidepressant derivatives of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine
US5290806A (en) * 1990-03-06 1994-03-01 Basf Aktiengesellschaft 4-(4-tert-butylphenyl) cyclohexylamines, and fungicides containing same
GB9114948D0 (en) * 1991-07-11 1991-08-28 Pfizer Ltd Process for preparing sertraline intermediates
IL112569A (en) * 1994-02-10 1999-12-22 Wyeth John & Brother Ltd Pharmaceutical compositions comprising cyclohexylamine derivatives certain such novel compounds and their preparation
HU222341B1 (hu) 1996-12-18 2003-06-28 Richter Gedeon Vegyészeti Gyár Rt. Eljárás sertralin előállítására és az eljárásban alkalmazott intermedier
DE19812054A1 (de) * 1998-03-19 1999-09-23 Hoechst Schering Agrevo Gmbh Verfahren zur Herstellung 4-substituierter cis-Cyclohexylamine

Also Published As

Publication number Publication date
IL138172A (en) 2007-09-20
ES2217748T3 (es) 2004-11-01
DE69916593D1 (de) 2004-05-27
EP1064250A1 (en) 2001-01-03
WO1999047486A1 (en) 1999-09-23
HUP0101322A2 (hu) 2002-05-29
CN1216033C (zh) 2005-08-24
CA2323629A1 (en) 1999-09-23
US6232501B1 (en) 2001-05-15
DE69916593T2 (de) 2005-05-25
TR200002673T2 (tr) 2000-11-21
AU3412899A (en) 1999-10-11
AR018164A1 (es) 2001-10-31
EP1064250B1 (en) 2004-04-21
IL138172A0 (en) 2001-10-31
AU759530B2 (en) 2003-04-17
TWI220427B (en) 2004-08-21
HUP0101322A3 (en) 2002-06-28
JP2002506844A (ja) 2002-03-05
PT1064250E (pt) 2004-09-30
CN1293653A (zh) 2001-05-02

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