TR200002673T2 - Sikloheksilidenaminlerin sis-seçici katalitik hidrojenasyonu işlemi. - Google Patents
Sikloheksilidenaminlerin sis-seçici katalitik hidrojenasyonu işlemi.Info
- Publication number
- TR200002673T2 TR200002673T2 TR2000/02673T TR200002673T TR200002673T2 TR 200002673 T2 TR200002673 T2 TR 200002673T2 TR 2000/02673 T TR2000/02673 T TR 2000/02673T TR 200002673 T TR200002673 T TR 200002673T TR 200002673 T2 TR200002673 T2 TR 200002673T2
- Authority
- TR
- Turkey
- Prior art keywords
- catalytic hydrogenation
- cyclohexylidenamines
- fog
- selective catalytic
- cyclic
- Prior art date
Links
- 238000009903 catalytic hydrogenation reaction Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- NNGAQKAUYDTUQR-UHFFFAOYSA-N cyclohexanimine Chemical class N=C1CCCCC1 NNGAQKAUYDTUQR-UHFFFAOYSA-N 0.000 title 1
- 239000003054 catalyst Substances 0.000 abstract 1
- -1 cyclic imines Chemical class 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
- VGKDLMBJGBXTGI-SJCJKPOMSA-N sertraline Chemical compound C1([C@@H]2CC[C@@H](C3=CC=CC=C32)NC)=CC=C(Cl)C(Cl)=C1 VGKDLMBJGBXTGI-SJCJKPOMSA-N 0.000 abstract 1
- 229960002073 sertraline Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/44—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers
- C07C209/52—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers by reduction of imines or imino-ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/09—Geometrical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH64598 | 1998-03-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200002673T2 true TR200002673T2 (tr) | 2000-11-21 |
Family
ID=4191841
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2000/02673T TR200002673T2 (tr) | 1998-03-18 | 1999-03-16 | Sikloheksilidenaminlerin sis-seçici katalitik hidrojenasyonu işlemi. |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US6232501B1 (https=) |
| EP (1) | EP1064250B1 (https=) |
| JP (1) | JP2002506844A (https=) |
| CN (1) | CN1216033C (https=) |
| AR (1) | AR018164A1 (https=) |
| AU (1) | AU759530B2 (https=) |
| CA (1) | CA2323629A1 (https=) |
| DE (1) | DE69916593T2 (https=) |
| ES (1) | ES2217748T3 (https=) |
| HU (1) | HUP0101322A3 (https=) |
| IL (2) | IL138172A0 (https=) |
| PT (1) | PT1064250E (https=) |
| TR (1) | TR200002673T2 (https=) |
| TW (1) | TWI220427B (https=) |
| WO (1) | WO1999047486A1 (https=) |
| ZA (1) | ZA200004624B (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6500987B1 (en) | 1998-11-27 | 2002-12-31 | Teva Pharmaceutical Industries Ltd. | Sertraline hydrochloride polymorphs |
| ATE264831T1 (de) | 1999-07-29 | 2004-05-15 | Ciba Sc Holding Ag | Verfahren zur cis-selektiven katalytischen hydrierung von cyclohexylidenaminen |
| US6495721B1 (en) | 1999-08-09 | 2002-12-17 | Teva Pharmaceutical Industries Ltd. | Sertraline hydrochloride Form II and methods for the preparation thereof |
| TWI260315B (en) | 1999-10-29 | 2006-08-21 | Ciba Sc Holding Ag | Polymorphic forms of sertraline hydrochloride |
| US7442838B2 (en) | 1999-10-29 | 2008-10-28 | Ciba Specialty Chemicals Corp. | Polymorphic forms of sertraline hydrochloride |
| EP1230211B1 (en) | 1999-11-16 | 2005-07-20 | Ciba SC Holding AG | Process for the preparation of ketimines |
| ATE295349T1 (de) * | 1999-11-16 | 2005-05-15 | Ciba Sc Holding Ag | Verfahren zur herstellung von ketiminen |
| ES2281374T3 (es) | 1999-12-21 | 2007-10-01 | Teva Pharmaceutical Industries Ltd. | Nuevos polimorfos de hidrocloruro de sertralina, procedimientos para su preparacion, composiciones que los contienen y metodos para su utilizacion. |
| CZ20023269A3 (cs) * | 2000-03-14 | 2003-09-17 | Teva Pharmaceutical Industries Ltd. | Způsob přípravy (+) -cis-sertralinu |
| US6723878B2 (en) | 2001-06-15 | 2004-04-20 | Orion Corporation Fermion | Method for preparing sertraline |
| AU2003251290A1 (en) | 2002-04-29 | 2003-11-17 | Teva Pharmaceutical Industries Ltd. | Process for preparation of polymorphic form ii of sertraline hydrochloride, pharmaceutical formulations and methods of administration thereof |
| ES2242555T1 (es) * | 2003-04-14 | 2005-11-16 | Teva Pharmaceutical Industries Limited | Hidrogenacion de intermediarios de imina de sertralina con catalizadores. |
| WO2006129324A2 (en) | 2005-06-03 | 2006-12-07 | Hetero Drugs Limited | A highly stereoselective synthesis of sertraline |
| US8354558B2 (en) * | 2007-12-21 | 2013-01-15 | Basf Se | Process for diastereoselective conversion of chiral imines |
| US8415500B2 (en) * | 2007-12-21 | 2013-04-09 | Basf Se | One-stage reductive amination |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4536518A (en) * | 1979-11-01 | 1985-08-20 | Pfizer Inc. | Antidepressant derivatives of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine |
| US5290806A (en) * | 1990-03-06 | 1994-03-01 | Basf Aktiengesellschaft | 4-(4-tert-butylphenyl) cyclohexylamines, and fungicides containing same |
| GB9114948D0 (en) * | 1991-07-11 | 1991-08-28 | Pfizer Ltd | Process for preparing sertraline intermediates |
| IL112569A (en) * | 1994-02-10 | 1999-12-22 | Wyeth John & Brother Ltd | Pharmaceutical compositions comprising cyclohexylamine derivatives certain such novel compounds and their preparation |
| HU222341B1 (hu) | 1996-12-18 | 2003-06-28 | Richter Gedeon Vegyészeti Gyár Rt. | Eljárás sertralin előállítására és az eljárásban alkalmazott intermedier |
| DE19812054A1 (de) * | 1998-03-19 | 1999-09-23 | Hoechst Schering Agrevo Gmbh | Verfahren zur Herstellung 4-substituierter cis-Cyclohexylamine |
-
1999
- 1999-03-16 ES ES99915616T patent/ES2217748T3/es not_active Expired - Lifetime
- 1999-03-16 US US09/646,211 patent/US6232501B1/en not_active Expired - Lifetime
- 1999-03-16 AR ARP990101137A patent/AR018164A1/es active IP Right Grant
- 1999-03-16 IL IL13817299A patent/IL138172A0/xx not_active IP Right Cessation
- 1999-03-16 TR TR2000/02673T patent/TR200002673T2/xx unknown
- 1999-03-16 CN CN998041378A patent/CN1216033C/zh not_active Expired - Fee Related
- 1999-03-16 HU HU0101322A patent/HUP0101322A3/hu unknown
- 1999-03-16 WO PCT/EP1999/001696 patent/WO1999047486A1/en not_active Ceased
- 1999-03-16 PT PT99915616T patent/PT1064250E/pt unknown
- 1999-03-16 DE DE69916593T patent/DE69916593T2/de not_active Expired - Lifetime
- 1999-03-16 AU AU34128/99A patent/AU759530B2/en not_active Ceased
- 1999-03-16 CA CA002323629A patent/CA2323629A1/en not_active Abandoned
- 1999-03-16 JP JP2000536684A patent/JP2002506844A/ja active Pending
- 1999-03-16 EP EP99915616A patent/EP1064250B1/en not_active Expired - Lifetime
- 1999-03-17 TW TW088104122A patent/TWI220427B/zh not_active IP Right Cessation
-
2000
- 2000-08-30 IL IL138172A patent/IL138172A/en unknown
- 2000-09-04 ZA ZA200004624A patent/ZA200004624B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL138172A (en) | 2007-09-20 |
| ES2217748T3 (es) | 2004-11-01 |
| DE69916593D1 (de) | 2004-05-27 |
| EP1064250A1 (en) | 2001-01-03 |
| WO1999047486A1 (en) | 1999-09-23 |
| HUP0101322A2 (hu) | 2002-05-29 |
| CN1216033C (zh) | 2005-08-24 |
| CA2323629A1 (en) | 1999-09-23 |
| US6232501B1 (en) | 2001-05-15 |
| DE69916593T2 (de) | 2005-05-25 |
| AU3412899A (en) | 1999-10-11 |
| AR018164A1 (es) | 2001-10-31 |
| EP1064250B1 (en) | 2004-04-21 |
| IL138172A0 (en) | 2001-10-31 |
| AU759530B2 (en) | 2003-04-17 |
| TWI220427B (en) | 2004-08-21 |
| ZA200004624B (en) | 2001-11-29 |
| HUP0101322A3 (en) | 2002-06-28 |
| JP2002506844A (ja) | 2002-03-05 |
| PT1064250E (pt) | 2004-09-30 |
| CN1293653A (zh) | 2001-05-02 |
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