YU69693A - Transdermalni terapijski sistem sa aktivnom materijom estradiol - Google Patents
Transdermalni terapijski sistem sa aktivnom materijom estradiolInfo
- Publication number
- YU69693A YU69693A YU69693A YU69693A YU69693A YU 69693 A YU69693 A YU 69693A YU 69693 A YU69693 A YU 69693A YU 69693 A YU69693 A YU 69693A YU 69693 A YU69693 A YU 69693A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- estradiol
- matrix layers
- therapy system
- concentration
- equilibrium
- Prior art date
Links
- VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 title abstract 5
- 229960005309 estradiol Drugs 0.000 title abstract 4
- 229930182833 estradiol Natural products 0.000 title abstract 3
- 238000002560 therapeutic procedure Methods 0.000 title abstract 2
- 239000011149 active material Substances 0.000 title 1
- 239000010410 layer Substances 0.000 abstract 4
- 239000011159 matrix material Substances 0.000 abstract 3
- 239000013543 active substance Substances 0.000 abstract 2
- 239000012790 adhesive layer Substances 0.000 abstract 2
- 239000000463 material Substances 0.000 abstract 2
- 230000001225 therapeutic effect Effects 0.000 abstract 2
- 239000000853 adhesive Substances 0.000 abstract 1
- 230000001070 adhesive effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4237453A DE4237453C1 (https=) | 1992-11-06 | 1992-11-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| YU69693A true YU69693A (sh) | 1997-07-31 |
Family
ID=6472230
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| YU69693A YU69693A (sh) | 1992-11-06 | 1993-11-03 | Transdermalni terapijski sistem sa aktivnom materijom estradiol |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US5912008A (https=) |
| EP (1) | EP0716599B1 (https=) |
| JP (1) | JP3237016B2 (https=) |
| KR (1) | KR100306946B1 (https=) |
| AT (1) | ATE164516T1 (https=) |
| AU (1) | AU678408B2 (https=) |
| CA (1) | CA2147172C (https=) |
| CZ (1) | CZ286907B6 (https=) |
| DE (2) | DE4237453C1 (https=) |
| DK (1) | DK0716599T3 (https=) |
| ES (1) | ES2117152T3 (https=) |
| FI (1) | FI113339B (https=) |
| HR (1) | HRP931360B1 (https=) |
| HU (1) | HU221847B1 (https=) |
| IL (1) | IL107395A (https=) |
| MY (1) | MY118171A (https=) |
| NO (1) | NO311783B1 (https=) |
| NZ (1) | NZ257137A (https=) |
| PL (1) | PL174604B1 (https=) |
| SI (1) | SI9300581A (https=) |
| SK (1) | SK279911B6 (https=) |
| WO (1) | WO1994010984A1 (https=) |
| YU (1) | YU69693A (https=) |
| ZA (1) | ZA938257B (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR930001804B1 (ko) * | 1989-02-28 | 1993-03-13 | 데이진 가부시끼가이샤 | 첩부제 및 그의 제조방법 |
| WO1994023707A1 (de) * | 1993-04-20 | 1994-10-27 | Hexal Pharma Gmbh | Wirkstoffplaster |
| DE4429664C2 (de) * | 1994-08-20 | 1997-09-11 | Lohmann Therapie Syst Lts | Estradiol-TTS mit wasserbindenden Zusätzen und Verfahren zu seiner Herstellung |
| US5906830A (en) * | 1995-09-08 | 1999-05-25 | Cygnus, Inc. | Supersaturated transdermal drug delivery systems, and methods for manufacturing the same |
| DE19600347A1 (de) * | 1996-01-08 | 1997-07-10 | Lohmann Therapie Syst Lts | Hauthaftende pharmazeutische Zubereitung, insbesondere TTS zur Abgabe von 17-beta-Estradiol an den menschlichen Organismus |
| DE19701949A1 (de) * | 1997-01-13 | 1998-07-16 | Jenapharm Gmbh | Transdermales therapeutisches System |
| US5968547A (en) | 1997-02-24 | 1999-10-19 | Euro-Celtique, S.A. | Method of providing sustained analgesia with buprenorphine |
| DE19827732A1 (de) * | 1998-06-22 | 1999-12-23 | Rottapharm Bv | Transdermales System vom Matrix-Typ zur Abgabe von Wirkstoffen mit einer hohen Abgaberate von Steroid-Hormonen und die Verwendung eines derartigen Systems zur Hormonersatztherapie |
| JP4399044B2 (ja) * | 1998-10-14 | 2010-01-13 | 久光製薬株式会社 | 吸収促進剤及び該吸収促進剤を有してなる経皮吸収製剤 |
| US6631186B1 (en) * | 1999-04-09 | 2003-10-07 | Sbc Technology Resources, Inc. | System and method for implementing and accessing call forwarding services |
| DE19925613A1 (de) * | 1999-06-04 | 2000-12-07 | Lohmann Therapie Syst Lts | Verbundlaminat und Verfahren zu seiner Herstellung |
| ITRM20060440A1 (it) * | 2006-08-10 | 2008-02-11 | Carmine Antropoli | Uso della nifedipina per il trattamento antirughe |
| US20100087768A1 (en) * | 2008-10-02 | 2010-04-08 | Forlano Paula | Transdermal drug delivery system for liquid active ingredient |
| DE102010026903A1 (de) | 2010-07-12 | 2012-01-12 | Amw Gmbh | Transdermales therapeutisches System mit Avocadoöl oder Palmöl als Hilfsstoff |
| ES2804263T3 (es) | 2011-07-05 | 2021-02-05 | Novan Inc | Composiciones tópicas |
| WO2013006613A1 (en) | 2011-07-05 | 2013-01-10 | Novan, Inc. | Methods of manufacturing topical compositions and apparatus for same |
| DE102012000369A1 (de) | 2012-01-11 | 2013-07-11 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Transdermales therapeutisches System mit Cholinesterase-Hemmer |
| US9855211B2 (en) | 2013-02-28 | 2018-01-02 | Novan, Inc. | Topical compositions and methods of using the same |
| US10322082B2 (en) | 2014-07-11 | 2019-06-18 | Novan, Inc. | Topical antiviral compositions and methods of using the same |
| CN106659675B (zh) | 2014-07-11 | 2023-07-04 | 诺万公司 | 局部抗病毒组合物和其使用方法 |
| CN109310630A (zh) | 2016-04-13 | 2019-02-05 | 诺万公司 | 用于治疗感染的组合物、系统、试剂盒和方法 |
| DE102017127433A1 (de) * | 2017-11-21 | 2019-05-23 | Lts Lohmann Therapie-Systeme Ag | TTS auf Basis von klebenden Weichmacher-Polymer-Matrices |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR527450A (fr) * | 1919-12-04 | 1921-10-25 | Gilbert Mahaut | Système et dispositif pour la combustion des huiles lourdes dans les foyers industriels et autres |
| US4435180A (en) * | 1982-05-25 | 1984-03-06 | Alza Corporation | Elastomeric active agent delivery system and method of use |
| GB2138286B (en) * | 1983-04-19 | 1986-10-08 | Dr Christopher Harry Mortimer | Pharmaceutical composition for the treatment of hair loss |
| ATE95430T1 (de) * | 1984-12-22 | 1993-10-15 | Sanol Arznei Schwarz Gmbh | Wirkstoffpflaster. |
| US5145682A (en) * | 1986-05-30 | 1992-09-08 | Rutgers, The State University Of New Jersey | Transdermal absorption dosage unit for postmenopausal syndrome treatment and process for administration |
| US5023084A (en) * | 1986-12-29 | 1991-06-11 | Rutgers, The State University Of New Jersey | Transdermal estrogen/progestin dosage unit, system and process |
| FR2612785A1 (fr) * | 1987-03-25 | 1988-09-30 | Lhd Lab Hygiene Dietetique | Dispositif auto-adhesif d'administration d'un principe actif par voie percutanee |
| US4863738A (en) * | 1987-11-23 | 1989-09-05 | Alza Corporation | Skin permeation enhancer compositions using glycerol monooleate |
| US4994267A (en) * | 1988-03-04 | 1991-02-19 | Noven Pharmaceuticals, Inc. | Transdermal acrylic multipolymer drug delivery system |
| KR930001804B1 (ko) * | 1989-02-28 | 1993-03-13 | 데이진 가부시끼가이샤 | 첩부제 및 그의 제조방법 |
| DE3933460A1 (de) * | 1989-10-06 | 1991-04-18 | Lohmann Therapie Syst Lts | Oestrogenhaltiges wirkstoffpflaster |
| WO1991005529A1 (en) * | 1989-10-13 | 1991-05-02 | Watson Laboratories, Inc. | Drug delivery systems and matrix therefor |
| AR246186A1 (es) * | 1989-11-17 | 1994-07-29 | Beta Pharm Co | Procedimiento para fabricar un dispositivo para administrar estradiol por via transdermica. |
| DE4002281A1 (de) * | 1990-01-26 | 1991-08-01 | Lohmann Therapie Syst Lts | Transdermales therapeutisches system mit dem wirkstoff tulobuterol |
| AU633733B2 (en) * | 1990-05-17 | 1993-02-04 | Hisamitsu Pharmaceutical Co., Inc. | Percutaneous preparation containing estradiol |
-
1992
- 1992-11-06 DE DE4237453A patent/DE4237453C1/de not_active Revoked
-
1993
- 1993-10-21 MY MYPI93002178A patent/MY118171A/en unknown
- 1993-10-25 IL IL10739593A patent/IL107395A/xx not_active IP Right Cessation
- 1993-10-27 CZ CZ19951162A patent/CZ286907B6/cs not_active IP Right Cessation
- 1993-10-27 WO PCT/EP1993/002971 patent/WO1994010984A1/de not_active Ceased
- 1993-10-27 CA CA002147172A patent/CA2147172C/en not_active Expired - Lifetime
- 1993-10-27 SK SK580-95A patent/SK279911B6/sk not_active IP Right Cessation
- 1993-10-27 HU HU9501318A patent/HU221847B1/hu active IP Right Grant
- 1993-10-27 EP EP93923559A patent/EP0716599B1/de not_active Expired - Lifetime
- 1993-10-27 PL PL93308532A patent/PL174604B1/pl unknown
- 1993-10-27 AT AT93923559T patent/ATE164516T1/de active
- 1993-10-27 NZ NZ257137A patent/NZ257137A/en not_active IP Right Cessation
- 1993-10-27 DE DE59308360T patent/DE59308360D1/de not_active Expired - Lifetime
- 1993-10-27 DK DK93923559T patent/DK0716599T3/da active
- 1993-10-27 ES ES93923559T patent/ES2117152T3/es not_active Expired - Lifetime
- 1993-10-27 JP JP51165094A patent/JP3237016B2/ja not_active Expired - Lifetime
- 1993-10-27 KR KR1019950701791A patent/KR100306946B1/ko not_active Expired - Lifetime
- 1993-10-27 AU AU53386/94A patent/AU678408B2/en not_active Expired
- 1993-11-03 YU YU69693A patent/YU69693A/sh unknown
- 1993-11-04 HR HRP4237453.7A patent/HRP931360B1/xx not_active IP Right Cessation
- 1993-11-05 ZA ZA938257A patent/ZA938257B/xx unknown
- 1993-11-05 SI SI9300581A patent/SI9300581A/sl unknown
-
1995
- 1995-05-03 FI FI952115A patent/FI113339B/fi not_active IP Right Cessation
- 1995-05-05 NO NO19951765A patent/NO311783B1/no not_active IP Right Cessation
-
1997
- 1997-06-16 US US08/876,427 patent/US5912008A/en not_active Expired - Lifetime
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| YU69693A (sh) | Transdermalni terapijski sistem sa aktivnom materijom estradiol | |
| YU48607B (sh) | Transdermalni terapeutski sistem (tts) za odavanje galantamina | |
| TR199902484T2 (xx) | Biyolojik y�nden aktif maddeler ihtiva eden yap���c� mikrokaps�ller | |
| MY111126A (en) | Transdermal therapeutic system comprising the active substance acetylsalicylic acid. | |
| FI950165A0 (fi) | Ihon läpäisevä terapeuttinen järjestelmä, jossa vaikuttavana aineena on 17-beta-estradioli (vedetön) | |
| KR900013993A (ko) | 활성물질의 국소 또는 계통적 투여를 위한 단계적 약물 방출을 나타내는 경피 시스템 및 그 용도 | |
| IL125160A (en) | Transdermal therapeutic composition, process for its preparation and use thereof | |
| YU49193A (sh) | Transdermalni terapijski sistem sa aktivnom materijom bezvodnim 17-beta-estradiolom | |
| AR019218A1 (es) | Sistema para la emision continua de principios activos a la piel y/o las mucosas, con el agregado de pigmentos de brillo perlino |