YU47950B - Postupak za dobivanje puferisanih metronidazolskih preparata - Google Patents
Postupak za dobivanje puferisanih metronidazolskih preparataInfo
- Publication number
- YU47950B YU47950B YU170090A YU170090A YU47950B YU 47950 B YU47950 B YU 47950B YU 170090 A YU170090 A YU 170090A YU 170090 A YU170090 A YU 170090A YU 47950 B YU47950 B YU 47950B
- Authority
- YU
- Yugoslavia
- Prior art keywords
- metronidazole
- puffered
- preparations
- procedure
- obtaining
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/04—Amoebicides
Abstract
POSTUPAK ZA DOBIVANJE PUFERISANIH METRONIDAZOLSKIH PREPARATA u obliku gela, naznačen time, što se metronidazol disperguje u geliran hidrofilan i u vodi disperzivan polimer poliakrilne kiseline koji ima slobodne karboksilno kiselinske grupe i molekulsku masu u oblasti od 1250000 do 4000000 Daltona i sadrži dovoljno baze da pH vrednost bude u oblasti 3,75 -4,25 i koji dalje sadrži vodu kao rastvarač za metronidazol i bazu. Prijava sadrži još 1 nezavisan i 9 zavisnih zahteva.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36227389A | 1989-06-06 | 1989-06-06 |
Publications (2)
Publication Number | Publication Date |
---|---|
YU170090A YU170090A (sh) | 1994-04-05 |
YU47950B true YU47950B (sh) | 1996-07-24 |
Family
ID=23425444
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU170090A YU47950B (sh) | 1989-06-06 | 1990-06-06 | Postupak za dobivanje puferisanih metronidazolskih preparata |
Country Status (21)
Country | Link |
---|---|
EP (1) | EP0404376B1 (sh) |
JP (1) | JP2999820B2 (sh) |
KR (1) | KR0169487B1 (sh) |
CN (1) | CN1054507C (sh) |
AT (1) | ATE103176T1 (sh) |
AU (1) | AU635752B2 (sh) |
BR (1) | BR9006793A (sh) |
CA (1) | CA1337279C (sh) |
DE (1) | DE69007547T2 (sh) |
DK (1) | DK0404376T3 (sh) |
ES (1) | ES2062366T3 (sh) |
HU (1) | HU207795B (sh) |
IE (1) | IE65413B1 (sh) |
IL (1) | IL94619A (sh) |
PH (1) | PH30718A (sh) |
PL (1) | PL164128B1 (sh) |
RO (1) | RO109156B1 (sh) |
RU (1) | RU2032402C1 (sh) |
WO (1) | WO1990014832A1 (sh) |
YU (1) | YU47950B (sh) |
ZA (1) | ZA904413B (sh) |
Families Citing this family (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5592949A (en) * | 1994-06-29 | 1997-01-14 | Moench; Thomas R. | Device for acidic buffering and method for inactivation of pathogens |
GB9626513D0 (en) * | 1996-12-20 | 1997-02-05 | Bioglan Ireland R & D Ltd | A pharmaceutical composition |
US8512718B2 (en) | 2000-07-03 | 2013-08-20 | Foamix Ltd. | Pharmaceutical composition for topical application |
CA2442281C (en) * | 2001-03-27 | 2010-06-08 | Galen (Chemicals) Limited | Intravaginal drug delivery devices for the administration of an antimicrobial agent |
GB0130666D0 (en) * | 2001-12-21 | 2002-02-06 | Accantla Holdings Ltd | Absorbent tampons |
US6899890B2 (en) * | 2002-03-20 | 2005-05-31 | Kv Pharmaceutical Company | Bioadhesive drug delivery system |
US7695730B2 (en) | 2002-05-01 | 2010-04-13 | Mcneil-Ppc, Inc. | Warming and nonirritating lubricant compositions and method of comparing irritation |
US7658941B2 (en) | 2002-05-01 | 2010-02-09 | Johnson & Johnson Consumer Companies, Inc. | Warming and nonirritating lubricant compositions and method of comparing irritation |
EP1620069B1 (en) * | 2002-05-01 | 2008-05-28 | McNEIL-PPC, INC. | Warming and nonirritating lubricant fungicide compositions in the form of a gel |
WO2003092652A1 (en) * | 2002-05-01 | 2003-11-13 | Mcneil-Ppc, Inc. | Warming and nonirritating anhydrous lubricant compositions |
US7005408B2 (en) * | 2002-05-01 | 2006-02-28 | Mcneil-Ppc, Inc. | Warming and nonirritating lubricant compositions and method of comparing irritation |
US7417013B2 (en) | 2002-05-01 | 2008-08-26 | Mcneil-Ppc, Inc. | Warming and nonirritating lubricant compositions and method of comparing irritation |
IL152486A0 (en) | 2002-10-25 | 2003-05-29 | Meir Eini | Alcohol-free cosmetic and pharmaceutical foam carrier |
US10117812B2 (en) | 2002-10-25 | 2018-11-06 | Foamix Pharmaceuticals Ltd. | Foamable composition combining a polar solvent and a hydrophobic carrier |
US8119109B2 (en) | 2002-10-25 | 2012-02-21 | Foamix Ltd. | Foamable compositions, kits and methods for hyperhidrosis |
US8486376B2 (en) | 2002-10-25 | 2013-07-16 | Foamix Ltd. | Moisturizing foam containing lanolin |
US7820145B2 (en) | 2003-08-04 | 2010-10-26 | Foamix Ltd. | Oleaginous pharmaceutical and cosmetic foam |
US9265725B2 (en) | 2002-10-25 | 2016-02-23 | Foamix Pharmaceuticals Ltd. | Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof |
US7704518B2 (en) | 2003-08-04 | 2010-04-27 | Foamix, Ltd. | Foamable vehicle and pharmaceutical compositions thereof |
US20080138296A1 (en) | 2002-10-25 | 2008-06-12 | Foamix Ltd. | Foam prepared from nanoemulsions and uses |
US9668972B2 (en) | 2002-10-25 | 2017-06-06 | Foamix Pharmaceuticals Ltd. | Nonsteroidal immunomodulating kit and composition and uses thereof |
US7700076B2 (en) | 2002-10-25 | 2010-04-20 | Foamix, Ltd. | Penetrating pharmaceutical foam |
US8119150B2 (en) | 2002-10-25 | 2012-02-21 | Foamix Ltd. | Non-flammable insecticide composition and uses thereof |
MXPA05004278A (es) | 2002-10-25 | 2005-10-05 | Foamix Ltd | Espuma cosmetica y farmaceutica. |
US9211259B2 (en) | 2002-11-29 | 2015-12-15 | Foamix Pharmaceuticals Ltd. | Antibiotic kit and composition and uses thereof |
US20050186142A1 (en) * | 2002-10-25 | 2005-08-25 | Foamix Ltd. | Kit and composition of imidazole with enhanced bioavailability |
US8900554B2 (en) | 2002-10-25 | 2014-12-02 | Foamix Pharmaceuticals Ltd. | Foamable composition and uses thereof |
US7575739B2 (en) | 2003-04-28 | 2009-08-18 | Foamix Ltd. | Foamable iodine composition |
WO2004110461A1 (en) * | 2003-06-13 | 2004-12-23 | Idh Holding Aps | Treatment of symptoms associated with bacterial vaginosis |
US8795693B2 (en) | 2003-08-04 | 2014-08-05 | Foamix Ltd. | Compositions with modulating agents |
US8486374B2 (en) | 2003-08-04 | 2013-07-16 | Foamix Ltd. | Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses |
US20060140990A1 (en) * | 2003-09-19 | 2006-06-29 | Drugtech Corporation | Composition for topical treatment of mixed vaginal infections |
BRPI0414500A (pt) | 2003-09-19 | 2006-11-07 | Drugtech Corp | formulação farmacêutica composição para tratar uma infecção vaginal, e, métodos para tratar uma infecção vaginal, para estabilizar uma formulação de clindamicina, para tratar ou prevenir uma recorrência de uma infecção vaginal em uma paciente e para tratar condições vaginais |
US7851419B2 (en) | 2005-09-12 | 2010-12-14 | Nawaz Ahmad | Substantially anhydrous sprayable personal lubricant |
US20070059250A1 (en) * | 2005-09-12 | 2007-03-15 | Nawaz Ahmad | Sprayable personal lubricant |
US20070154516A1 (en) * | 2006-01-05 | 2007-07-05 | Drugtech Corporation | Drug delivery system |
US20070224226A1 (en) * | 2006-01-05 | 2007-09-27 | Drugtech Corporation | Composition and method of use thereof |
US20080260655A1 (en) | 2006-11-14 | 2008-10-23 | Dov Tamarkin | Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses |
US8636982B2 (en) | 2007-08-07 | 2014-01-28 | Foamix Ltd. | Wax foamable vehicle and pharmaceutical compositions thereof |
WO2009069006A2 (en) | 2007-11-30 | 2009-06-04 | Foamix Ltd. | Foam containing benzoyl peroxide |
WO2009072007A2 (en) | 2007-12-07 | 2009-06-11 | Foamix Ltd. | Carriers, formulations, methods for formulating unstable active agents for external application and uses thereof |
WO2010041141A2 (en) | 2008-10-07 | 2010-04-15 | Foamix Ltd. | Oil-based foamable carriers and formulations |
CA2712120A1 (en) | 2008-01-14 | 2009-07-23 | Foamix Ltd. | Poloxamer foamable pharmaceutical compositions with active agents and/or therapeutic cells and uses |
EA021943B1 (ru) * | 2009-01-09 | 2015-10-30 | Эгиш Дьёдьсердьяр Ньильваношан Мюкеде Ресвеньтаршашаг | Способ изготовления вагинального суппозитория |
WO2010125470A2 (en) | 2009-04-28 | 2010-11-04 | Foamix Ltd. | Foamable vehicle and pharmaceutical compositions comprising aprotic polar solvents and uses thereof |
CA2769677A1 (en) | 2009-07-29 | 2011-02-03 | Foamix Ltd. | Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses |
WO2011013009A2 (en) | 2009-07-29 | 2011-02-03 | Foamix Ltd. | Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses |
CA2776474C (en) | 2009-10-02 | 2021-01-12 | Foamix Ltd. | Topical tetracycline compositions |
US9849142B2 (en) | 2009-10-02 | 2017-12-26 | Foamix Pharmaceuticals Ltd. | Methods for accelerated return of skin integrity and for the treatment of impetigo |
MX2014000066A (es) | 2011-06-28 | 2014-05-01 | Medicis Pharmaceutical Corp | Formulaciones mucoadhesivas en gel de alta dosificación de metronidazol de base acuosa y su uso para tratar la vaginosis bacteriana. |
WO2014210156A1 (en) | 2013-06-25 | 2014-12-31 | Mission Pharmacal Company | Novel formulations for the treatment of vaginal disorders |
MX2020012139A (es) | 2016-09-08 | 2021-01-29 | Vyne Pharmaceuticals Inc | Composiciones y metodos para tratar rosacea y acne. |
RU2730021C1 (ru) * | 2019-10-08 | 2020-08-14 | Общество с ограниченной ответственностью "Научно-производственная фирма ВЕРТА" | Средство местного применения для лечения инфекционных вагинитов |
CN112773780A (zh) * | 2019-11-11 | 2021-05-11 | 深圳优丽康生物技术有限公司 | 一种阴道外阴用组合物及其用途 |
RU2726123C1 (ru) * | 2019-12-20 | 2020-07-09 | Федеральное государственное бюджетное учреждение науки Оренбургский федеральный исследовательский центр Уральского отделения Российской академии наук | Способ лечения трихомониаза у женщин |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0024023B2 (de) * | 1979-08-11 | 1992-11-11 | Bayer Ag | Antimykotische Mittel mit höherer Freisetzung der Wirkstoffe |
US4602040A (en) * | 1983-04-18 | 1986-07-22 | Warner-Lambert Company | Meclofenamic acid topical pharmaceutical composition |
US4837378A (en) * | 1986-01-15 | 1989-06-06 | Curatek Pharmaceuticals, Inc. | Topical metronidazole formulations and therapeutic uses thereof |
GB8607159D0 (en) * | 1986-03-22 | 1986-04-30 | Smith & Nephew Ass | Pharmaceutical composition |
SE8603338D0 (sv) * | 1986-08-07 | 1986-08-07 | Bjorn Andersch | Medel for behandling av tillstand i slidan |
-
1989
- 1989-09-28 CA CA000613846A patent/CA1337279C/en not_active Expired - Lifetime
-
1990
- 1990-06-04 AU AU58294/90A patent/AU635752B2/en not_active Expired
- 1990-06-04 WO PCT/US1990/003195 patent/WO1990014832A1/en active Application Filing
- 1990-06-04 JP JP2508862A patent/JP2999820B2/ja not_active Expired - Fee Related
- 1990-06-04 RO RO146869A patent/RO109156B1/ro unknown
- 1990-06-04 BR BR909006793A patent/BR9006793A/pt not_active Application Discontinuation
- 1990-06-04 HU HU904720A patent/HU207795B/hu unknown
- 1990-06-04 KR KR1019910700140A patent/KR0169487B1/ko not_active IP Right Cessation
- 1990-06-05 DK DK90306026.7T patent/DK0404376T3/da active
- 1990-06-05 CN CN90104911A patent/CN1054507C/zh not_active Expired - Fee Related
- 1990-06-05 IL IL9461990A patent/IL94619A/en unknown
- 1990-06-05 PH PH40620A patent/PH30718A/en unknown
- 1990-06-05 AT AT90306026T patent/ATE103176T1/de not_active IP Right Cessation
- 1990-06-05 EP EP90306026A patent/EP0404376B1/en not_active Expired - Lifetime
- 1990-06-05 IE IE201190A patent/IE65413B1/en not_active IP Right Cessation
- 1990-06-05 ES ES90306026T patent/ES2062366T3/es not_active Expired - Lifetime
- 1990-06-05 DE DE69007547T patent/DE69007547T2/de not_active Expired - Lifetime
- 1990-06-06 PL PL90285507A patent/PL164128B1/pl unknown
- 1990-06-06 YU YU170090A patent/YU47950B/sh unknown
- 1990-06-07 ZA ZA904413A patent/ZA904413B/xx unknown
-
1991
- 1991-02-05 RU SU914894747A patent/RU2032402C1/ru active
Also Published As
Publication number | Publication date |
---|---|
RO109156B1 (ro) | 1994-12-30 |
ES2062366T3 (es) | 1994-12-16 |
ZA904413B (en) | 1991-04-24 |
HU904720D0 (en) | 1991-07-29 |
ATE103176T1 (de) | 1994-04-15 |
PL285507A1 (en) | 1992-01-13 |
PH30718A (en) | 1997-09-23 |
BR9006793A (pt) | 1991-08-06 |
YU170090A (sh) | 1994-04-05 |
AU635752B2 (en) | 1993-04-01 |
JP2999820B2 (ja) | 2000-01-17 |
DE69007547D1 (de) | 1994-04-28 |
WO1990014832A1 (en) | 1990-12-13 |
JPH04500365A (ja) | 1992-01-23 |
IL94619A0 (en) | 1991-04-15 |
RU2032402C1 (ru) | 1995-04-10 |
IE902011L (en) | 1990-12-06 |
DK0404376T3 (da) | 1994-05-24 |
HU207795B (en) | 1993-06-28 |
DE69007547T2 (de) | 1994-07-14 |
KR0169487B1 (ko) | 1999-01-15 |
CA1337279C (en) | 1995-10-10 |
CN1049101A (zh) | 1991-02-13 |
IE65413B1 (en) | 1995-10-18 |
PL164128B1 (pl) | 1994-06-30 |
EP0404376B1 (en) | 1994-03-23 |
EP0404376A2 (en) | 1990-12-27 |
AU5829490A (en) | 1991-01-07 |
HUT56490A (en) | 1991-09-30 |
EP0404376A3 (en) | 1991-06-05 |
CN1054507C (zh) | 2000-07-19 |
IL94619A (en) | 1995-01-24 |
KR920700032A (ko) | 1992-02-19 |
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