ES2062366T3 - Tratamiento intravaginal mejorado de infecciones vaginales con composiciones tamponadas de metronidazol. - Google Patents

Tratamiento intravaginal mejorado de infecciones vaginales con composiciones tamponadas de metronidazol.

Info

Publication number
ES2062366T3
ES2062366T3 ES90306026T ES90306026T ES2062366T3 ES 2062366 T3 ES2062366 T3 ES 2062366T3 ES 90306026 T ES90306026 T ES 90306026T ES 90306026 T ES90306026 T ES 90306026T ES 2062366 T3 ES2062366 T3 ES 2062366T3
Authority
ES
Spain
Prior art keywords
metronidazole
vaginal infections
composition
buffered compositions
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90306026T
Other languages
English (en)
Inventor
Robert J Borgman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Curatek Pharmaceuticals Inc
Original Assignee
Curatek Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Curatek Pharmaceuticals Inc filed Critical Curatek Pharmaceuticals Inc
Application granted granted Critical
Publication of ES2062366T3 publication Critical patent/ES2062366T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/04—Amoebicides

Abstract

UNA COMPOSICION Y METODO PARA TRATAR LA VAGINOSIS BACTERIAL Y/O TICLOMONIOSIS. LA VAGINA AFECTADA SE TRATA CON UNA CANTIDAD TERAPEUTICAMENTE EFECTIVA DE UNA COMPOSICION DE TAMPONADO DE METRONIDAPOLA QUE TIENE UN PH DE 5 A 4.25 PREFERENTEMENTE DE 3.75 A 4.25. UNA COMPOSICION DESTACADA COMPRENDE METRONIDAPOLA, YN GEL HIDROFOBICO Y UN POLIMERO DISPERSABEL EN AGUA, TAL COMO UN ACIDO POLIACRILICO QUE TIENEN UN PESO MOLECULAR DE 1.250.000 A 4.000.000 DE DALTONES, Y UN DISOLVENTE PARA LA METRONIDAPOLA.
ES90306026T 1989-06-06 1990-06-05 Tratamiento intravaginal mejorado de infecciones vaginales con composiciones tamponadas de metronidazol. Expired - Lifetime ES2062366T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US36227389A 1989-06-06 1989-06-06

Publications (1)

Publication Number Publication Date
ES2062366T3 true ES2062366T3 (es) 1994-12-16

Family

ID=23425444

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90306026T Expired - Lifetime ES2062366T3 (es) 1989-06-06 1990-06-05 Tratamiento intravaginal mejorado de infecciones vaginales con composiciones tamponadas de metronidazol.

Country Status (21)

Country Link
EP (1) EP0404376B1 (es)
JP (1) JP2999820B2 (es)
KR (1) KR0169487B1 (es)
CN (1) CN1054507C (es)
AT (1) ATE103176T1 (es)
AU (1) AU635752B2 (es)
BR (1) BR9006793A (es)
CA (1) CA1337279C (es)
DE (1) DE69007547T2 (es)
DK (1) DK0404376T3 (es)
ES (1) ES2062366T3 (es)
HU (1) HU207795B (es)
IE (1) IE65413B1 (es)
IL (1) IL94619A (es)
PH (1) PH30718A (es)
PL (1) PL164128B1 (es)
RO (1) RO109156B1 (es)
RU (1) RU2032402C1 (es)
WO (1) WO1990014832A1 (es)
YU (1) YU47950B (es)
ZA (1) ZA904413B (es)

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CA2442281C (en) * 2001-03-27 2010-06-08 Galen (Chemicals) Limited Intravaginal drug delivery devices for the administration of an antimicrobial agent
GB0130666D0 (en) * 2001-12-21 2002-02-06 Accantla Holdings Ltd Absorbent tampons
US6899890B2 (en) * 2002-03-20 2005-05-31 Kv Pharmaceutical Company Bioadhesive drug delivery system
US7695730B2 (en) 2002-05-01 2010-04-13 Mcneil-Ppc, Inc. Warming and nonirritating lubricant compositions and method of comparing irritation
US7658941B2 (en) 2002-05-01 2010-02-09 Johnson & Johnson Consumer Companies, Inc. Warming and nonirritating lubricant compositions and method of comparing irritation
EP1620069B1 (en) * 2002-05-01 2008-05-28 McNEIL-PPC, INC. Warming and nonirritating lubricant fungicide compositions in the form of a gel
WO2003092652A1 (en) * 2002-05-01 2003-11-13 Mcneil-Ppc, Inc. Warming and nonirritating anhydrous lubricant compositions
US7005408B2 (en) * 2002-05-01 2006-02-28 Mcneil-Ppc, Inc. Warming and nonirritating lubricant compositions and method of comparing irritation
US7417013B2 (en) 2002-05-01 2008-08-26 Mcneil-Ppc, Inc. Warming and nonirritating lubricant compositions and method of comparing irritation
IL152486A0 (en) 2002-10-25 2003-05-29 Meir Eini Alcohol-free cosmetic and pharmaceutical foam carrier
US10117812B2 (en) 2002-10-25 2018-11-06 Foamix Pharmaceuticals Ltd. Foamable composition combining a polar solvent and a hydrophobic carrier
US8119109B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Foamable compositions, kits and methods for hyperhidrosis
US8486376B2 (en) 2002-10-25 2013-07-16 Foamix Ltd. Moisturizing foam containing lanolin
US7820145B2 (en) 2003-08-04 2010-10-26 Foamix Ltd. Oleaginous pharmaceutical and cosmetic foam
US9265725B2 (en) 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
US7704518B2 (en) 2003-08-04 2010-04-27 Foamix, Ltd. Foamable vehicle and pharmaceutical compositions thereof
US20080138296A1 (en) 2002-10-25 2008-06-12 Foamix Ltd. Foam prepared from nanoemulsions and uses
US9668972B2 (en) 2002-10-25 2017-06-06 Foamix Pharmaceuticals Ltd. Nonsteroidal immunomodulating kit and composition and uses thereof
US7700076B2 (en) 2002-10-25 2010-04-20 Foamix, Ltd. Penetrating pharmaceutical foam
US8119150B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Non-flammable insecticide composition and uses thereof
MXPA05004278A (es) 2002-10-25 2005-10-05 Foamix Ltd Espuma cosmetica y farmaceutica.
US9211259B2 (en) 2002-11-29 2015-12-15 Foamix Pharmaceuticals Ltd. Antibiotic kit and composition and uses thereof
US20050186142A1 (en) * 2002-10-25 2005-08-25 Foamix Ltd. Kit and composition of imidazole with enhanced bioavailability
US8900554B2 (en) 2002-10-25 2014-12-02 Foamix Pharmaceuticals Ltd. Foamable composition and uses thereof
US7575739B2 (en) 2003-04-28 2009-08-18 Foamix Ltd. Foamable iodine composition
WO2004110461A1 (en) * 2003-06-13 2004-12-23 Idh Holding Aps Treatment of symptoms associated with bacterial vaginosis
US8795693B2 (en) 2003-08-04 2014-08-05 Foamix Ltd. Compositions with modulating agents
US8486374B2 (en) 2003-08-04 2013-07-16 Foamix Ltd. Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses
US20060140990A1 (en) * 2003-09-19 2006-06-29 Drugtech Corporation Composition for topical treatment of mixed vaginal infections
BRPI0414500A (pt) 2003-09-19 2006-11-07 Drugtech Corp formulação farmacêutica composição para tratar uma infecção vaginal, e, métodos para tratar uma infecção vaginal, para estabilizar uma formulação de clindamicina, para tratar ou prevenir uma recorrência de uma infecção vaginal em uma paciente e para tratar condições vaginais
US7851419B2 (en) 2005-09-12 2010-12-14 Nawaz Ahmad Substantially anhydrous sprayable personal lubricant
US20070059250A1 (en) * 2005-09-12 2007-03-15 Nawaz Ahmad Sprayable personal lubricant
US20070154516A1 (en) * 2006-01-05 2007-07-05 Drugtech Corporation Drug delivery system
US20070224226A1 (en) * 2006-01-05 2007-09-27 Drugtech Corporation Composition and method of use thereof
US20080260655A1 (en) 2006-11-14 2008-10-23 Dov Tamarkin Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses
US8636982B2 (en) 2007-08-07 2014-01-28 Foamix Ltd. Wax foamable vehicle and pharmaceutical compositions thereof
WO2009069006A2 (en) 2007-11-30 2009-06-04 Foamix Ltd. Foam containing benzoyl peroxide
WO2009072007A2 (en) 2007-12-07 2009-06-11 Foamix Ltd. Carriers, formulations, methods for formulating unstable active agents for external application and uses thereof
WO2010041141A2 (en) 2008-10-07 2010-04-15 Foamix Ltd. Oil-based foamable carriers and formulations
CA2712120A1 (en) 2008-01-14 2009-07-23 Foamix Ltd. Poloxamer foamable pharmaceutical compositions with active agents and/or therapeutic cells and uses
EA021943B1 (ru) * 2009-01-09 2015-10-30 Эгиш Дьёдьсердьяр Ньильваношан Мюкеде Ресвеньтаршашаг Способ изготовления вагинального суппозитория
WO2010125470A2 (en) 2009-04-28 2010-11-04 Foamix Ltd. Foamable vehicle and pharmaceutical compositions comprising aprotic polar solvents and uses thereof
CA2769677A1 (en) 2009-07-29 2011-02-03 Foamix Ltd. Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses
WO2011013009A2 (en) 2009-07-29 2011-02-03 Foamix Ltd. Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses
CA2776474C (en) 2009-10-02 2021-01-12 Foamix Ltd. Topical tetracycline compositions
US9849142B2 (en) 2009-10-02 2017-12-26 Foamix Pharmaceuticals Ltd. Methods for accelerated return of skin integrity and for the treatment of impetigo
MX2014000066A (es) 2011-06-28 2014-05-01 Medicis Pharmaceutical Corp Formulaciones mucoadhesivas en gel de alta dosificación de metronidazol de base acuosa y su uso para tratar la vaginosis bacteriana.
WO2014210156A1 (en) 2013-06-25 2014-12-31 Mission Pharmacal Company Novel formulations for the treatment of vaginal disorders
MX2020012139A (es) 2016-09-08 2021-01-29 Vyne Pharmaceuticals Inc Composiciones y metodos para tratar rosacea y acne.
RU2730021C1 (ru) * 2019-10-08 2020-08-14 Общество с ограниченной ответственностью "Научно-производственная фирма ВЕРТА" Средство местного применения для лечения инфекционных вагинитов
CN112773780A (zh) * 2019-11-11 2021-05-11 深圳优丽康生物技术有限公司 一种阴道外阴用组合物及其用途
RU2726123C1 (ru) * 2019-12-20 2020-07-09 Федеральное государственное бюджетное учреждение науки Оренбургский федеральный исследовательский центр Уральского отделения Российской академии наук Способ лечения трихомониаза у женщин

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SE8603338D0 (sv) * 1986-08-07 1986-08-07 Bjorn Andersch Medel for behandling av tillstand i slidan

Also Published As

Publication number Publication date
RO109156B1 (ro) 1994-12-30
ZA904413B (en) 1991-04-24
HU904720D0 (en) 1991-07-29
ATE103176T1 (de) 1994-04-15
PL285507A1 (en) 1992-01-13
PH30718A (en) 1997-09-23
BR9006793A (pt) 1991-08-06
YU170090A (sh) 1994-04-05
AU635752B2 (en) 1993-04-01
JP2999820B2 (ja) 2000-01-17
DE69007547D1 (de) 1994-04-28
WO1990014832A1 (en) 1990-12-13
JPH04500365A (ja) 1992-01-23
IL94619A0 (en) 1991-04-15
RU2032402C1 (ru) 1995-04-10
IE902011L (en) 1990-12-06
DK0404376T3 (da) 1994-05-24
HU207795B (en) 1993-06-28
DE69007547T2 (de) 1994-07-14
KR0169487B1 (ko) 1999-01-15
CA1337279C (en) 1995-10-10
YU47950B (sh) 1996-07-24
CN1049101A (zh) 1991-02-13
IE65413B1 (en) 1995-10-18
PL164128B1 (pl) 1994-06-30
EP0404376B1 (en) 1994-03-23
EP0404376A2 (en) 1990-12-27
AU5829490A (en) 1991-01-07
HUT56490A (en) 1991-09-30
EP0404376A3 (en) 1991-06-05
CN1054507C (zh) 2000-07-19
IL94619A (en) 1995-01-24
KR920700032A (ko) 1992-02-19

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