DE69007547T2 - Gepufferte Metronidazolmittel zur intravaginalen Behandlung vaginaler Infektionen. - Google Patents

Gepufferte Metronidazolmittel zur intravaginalen Behandlung vaginaler Infektionen.

Info

Publication number
DE69007547T2
DE69007547T2 DE69007547T DE69007547T DE69007547T2 DE 69007547 T2 DE69007547 T2 DE 69007547T2 DE 69007547 T DE69007547 T DE 69007547T DE 69007547 T DE69007547 T DE 69007547T DE 69007547 T2 DE69007547 T2 DE 69007547T2
Authority
DE
Germany
Prior art keywords
metronidazole
agents
vaginal infections
buffered
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69007547T
Other languages
English (en)
Other versions
DE69007547D1 (de
Inventor
Robert J Borgman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Meda AB
Original Assignee
CURATEK PHARMACEUTICALS ELK GROVE VILLAGE ILL LP
Curatek Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CURATEK PHARMACEUTICALS ELK GROVE VILLAGE ILL LP, Curatek Pharmaceuticals Inc filed Critical CURATEK PHARMACEUTICALS ELK GROVE VILLAGE ILL LP
Publication of DE69007547D1 publication Critical patent/DE69007547D1/de
Application granted granted Critical
Publication of DE69007547T2 publication Critical patent/DE69007547T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/04—Amoebicides
DE69007547T 1989-06-06 1990-06-05 Gepufferte Metronidazolmittel zur intravaginalen Behandlung vaginaler Infektionen. Expired - Lifetime DE69007547T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US36227389A 1989-06-06 1989-06-06

Publications (2)

Publication Number Publication Date
DE69007547D1 DE69007547D1 (de) 1994-04-28
DE69007547T2 true DE69007547T2 (de) 1994-07-14

Family

ID=23425444

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69007547T Expired - Lifetime DE69007547T2 (de) 1989-06-06 1990-06-05 Gepufferte Metronidazolmittel zur intravaginalen Behandlung vaginaler Infektionen.

Country Status (21)

Country Link
EP (1) EP0404376B1 (de)
JP (1) JP2999820B2 (de)
KR (1) KR0169487B1 (de)
CN (1) CN1054507C (de)
AT (1) ATE103176T1 (de)
AU (1) AU635752B2 (de)
BR (1) BR9006793A (de)
CA (1) CA1337279C (de)
DE (1) DE69007547T2 (de)
DK (1) DK0404376T3 (de)
ES (1) ES2062366T3 (de)
HU (1) HU207795B (de)
IE (1) IE65413B1 (de)
IL (1) IL94619A (de)
PH (1) PH30718A (de)
PL (1) PL164128B1 (de)
RO (1) RO109156B1 (de)
RU (1) RU2032402C1 (de)
WO (1) WO1990014832A1 (de)
YU (1) YU47950B (de)
ZA (1) ZA904413B (de)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5592949A (en) * 1994-06-29 1997-01-14 Moench; Thomas R. Device for acidic buffering and method for inactivation of pathogens
GB9626513D0 (en) * 1996-12-20 1997-02-05 Bioglan Ireland R & D Ltd A pharmaceutical composition
US8512718B2 (en) 2000-07-03 2013-08-20 Foamix Ltd. Pharmaceutical composition for topical application
CA2442281C (en) * 2001-03-27 2010-06-08 Galen (Chemicals) Limited Intravaginal drug delivery devices for the administration of an antimicrobial agent
GB0130666D0 (en) * 2001-12-21 2002-02-06 Accantla Holdings Ltd Absorbent tampons
US6899890B2 (en) * 2002-03-20 2005-05-31 Kv Pharmaceutical Company Bioadhesive drug delivery system
US7695730B2 (en) 2002-05-01 2010-04-13 Mcneil-Ppc, Inc. Warming and nonirritating lubricant compositions and method of comparing irritation
US7658941B2 (en) 2002-05-01 2010-02-09 Johnson & Johnson Consumer Companies, Inc. Warming and nonirritating lubricant compositions and method of comparing irritation
EP1620069B1 (de) * 2002-05-01 2008-05-28 McNEIL-PPC, INC. Erwärmende und nicht irritierende antifungale schmiermittelzubereitung in gelform
WO2003092652A1 (en) * 2002-05-01 2003-11-13 Mcneil-Ppc, Inc. Warming and nonirritating anhydrous lubricant compositions
US7005408B2 (en) * 2002-05-01 2006-02-28 Mcneil-Ppc, Inc. Warming and nonirritating lubricant compositions and method of comparing irritation
US7417013B2 (en) 2002-05-01 2008-08-26 Mcneil-Ppc, Inc. Warming and nonirritating lubricant compositions and method of comparing irritation
IL152486A0 (en) 2002-10-25 2003-05-29 Meir Eini Alcohol-free cosmetic and pharmaceutical foam carrier
US10117812B2 (en) 2002-10-25 2018-11-06 Foamix Pharmaceuticals Ltd. Foamable composition combining a polar solvent and a hydrophobic carrier
US8119109B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Foamable compositions, kits and methods for hyperhidrosis
US8486376B2 (en) 2002-10-25 2013-07-16 Foamix Ltd. Moisturizing foam containing lanolin
US7820145B2 (en) 2003-08-04 2010-10-26 Foamix Ltd. Oleaginous pharmaceutical and cosmetic foam
US9265725B2 (en) 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
US7704518B2 (en) 2003-08-04 2010-04-27 Foamix, Ltd. Foamable vehicle and pharmaceutical compositions thereof
US20080138296A1 (en) 2002-10-25 2008-06-12 Foamix Ltd. Foam prepared from nanoemulsions and uses
US9668972B2 (en) 2002-10-25 2017-06-06 Foamix Pharmaceuticals Ltd. Nonsteroidal immunomodulating kit and composition and uses thereof
US7700076B2 (en) 2002-10-25 2010-04-20 Foamix, Ltd. Penetrating pharmaceutical foam
US8119150B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Non-flammable insecticide composition and uses thereof
MXPA05004278A (es) 2002-10-25 2005-10-05 Foamix Ltd Espuma cosmetica y farmaceutica.
US9211259B2 (en) 2002-11-29 2015-12-15 Foamix Pharmaceuticals Ltd. Antibiotic kit and composition and uses thereof
US20050186142A1 (en) * 2002-10-25 2005-08-25 Foamix Ltd. Kit and composition of imidazole with enhanced bioavailability
US8900554B2 (en) 2002-10-25 2014-12-02 Foamix Pharmaceuticals Ltd. Foamable composition and uses thereof
US7575739B2 (en) 2003-04-28 2009-08-18 Foamix Ltd. Foamable iodine composition
WO2004110461A1 (en) * 2003-06-13 2004-12-23 Idh Holding Aps Treatment of symptoms associated with bacterial vaginosis
US8795693B2 (en) 2003-08-04 2014-08-05 Foamix Ltd. Compositions with modulating agents
US8486374B2 (en) 2003-08-04 2013-07-16 Foamix Ltd. Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses
US20060140990A1 (en) * 2003-09-19 2006-06-29 Drugtech Corporation Composition for topical treatment of mixed vaginal infections
BRPI0414500A (pt) 2003-09-19 2006-11-07 Drugtech Corp formulação farmacêutica composição para tratar uma infecção vaginal, e, métodos para tratar uma infecção vaginal, para estabilizar uma formulação de clindamicina, para tratar ou prevenir uma recorrência de uma infecção vaginal em uma paciente e para tratar condições vaginais
US7851419B2 (en) 2005-09-12 2010-12-14 Nawaz Ahmad Substantially anhydrous sprayable personal lubricant
US20070059250A1 (en) * 2005-09-12 2007-03-15 Nawaz Ahmad Sprayable personal lubricant
US20070154516A1 (en) * 2006-01-05 2007-07-05 Drugtech Corporation Drug delivery system
US20070224226A1 (en) * 2006-01-05 2007-09-27 Drugtech Corporation Composition and method of use thereof
US20080260655A1 (en) 2006-11-14 2008-10-23 Dov Tamarkin Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses
US8636982B2 (en) 2007-08-07 2014-01-28 Foamix Ltd. Wax foamable vehicle and pharmaceutical compositions thereof
WO2009069006A2 (en) 2007-11-30 2009-06-04 Foamix Ltd. Foam containing benzoyl peroxide
WO2009072007A2 (en) 2007-12-07 2009-06-11 Foamix Ltd. Carriers, formulations, methods for formulating unstable active agents for external application and uses thereof
WO2010041141A2 (en) 2008-10-07 2010-04-15 Foamix Ltd. Oil-based foamable carriers and formulations
CA2712120A1 (en) 2008-01-14 2009-07-23 Foamix Ltd. Poloxamer foamable pharmaceutical compositions with active agents and/or therapeutic cells and uses
EA021943B1 (ru) * 2009-01-09 2015-10-30 Эгиш Дьёдьсердьяр Ньильваношан Мюкеде Ресвеньтаршашаг Способ изготовления вагинального суппозитория
WO2010125470A2 (en) 2009-04-28 2010-11-04 Foamix Ltd. Foamable vehicle and pharmaceutical compositions comprising aprotic polar solvents and uses thereof
CA2769677A1 (en) 2009-07-29 2011-02-03 Foamix Ltd. Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses
WO2011013009A2 (en) 2009-07-29 2011-02-03 Foamix Ltd. Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses
CA2776474C (en) 2009-10-02 2021-01-12 Foamix Ltd. Topical tetracycline compositions
US9849142B2 (en) 2009-10-02 2017-12-26 Foamix Pharmaceuticals Ltd. Methods for accelerated return of skin integrity and for the treatment of impetigo
MX2014000066A (es) 2011-06-28 2014-05-01 Medicis Pharmaceutical Corp Formulaciones mucoadhesivas en gel de alta dosificación de metronidazol de base acuosa y su uso para tratar la vaginosis bacteriana.
WO2014210156A1 (en) 2013-06-25 2014-12-31 Mission Pharmacal Company Novel formulations for the treatment of vaginal disorders
MX2020012139A (es) 2016-09-08 2021-01-29 Vyne Pharmaceuticals Inc Composiciones y metodos para tratar rosacea y acne.
RU2730021C1 (ru) * 2019-10-08 2020-08-14 Общество с ограниченной ответственностью "Научно-производственная фирма ВЕРТА" Средство местного применения для лечения инфекционных вагинитов
CN112773780A (zh) * 2019-11-11 2021-05-11 深圳优丽康生物技术有限公司 一种阴道外阴用组合物及其用途
RU2726123C1 (ru) * 2019-12-20 2020-07-09 Федеральное государственное бюджетное учреждение науки Оренбургский федеральный исследовательский центр Уральского отделения Российской академии наук Способ лечения трихомониаза у женщин

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0024023B2 (de) * 1979-08-11 1992-11-11 Bayer Ag Antimykotische Mittel mit höherer Freisetzung der Wirkstoffe
US4602040A (en) * 1983-04-18 1986-07-22 Warner-Lambert Company Meclofenamic acid topical pharmaceutical composition
US4837378A (en) * 1986-01-15 1989-06-06 Curatek Pharmaceuticals, Inc. Topical metronidazole formulations and therapeutic uses thereof
GB8607159D0 (en) * 1986-03-22 1986-04-30 Smith & Nephew Ass Pharmaceutical composition
SE8603338D0 (sv) * 1986-08-07 1986-08-07 Bjorn Andersch Medel for behandling av tillstand i slidan

Also Published As

Publication number Publication date
RO109156B1 (ro) 1994-12-30
ES2062366T3 (es) 1994-12-16
ZA904413B (en) 1991-04-24
HU904720D0 (en) 1991-07-29
ATE103176T1 (de) 1994-04-15
PL285507A1 (en) 1992-01-13
PH30718A (en) 1997-09-23
BR9006793A (pt) 1991-08-06
YU170090A (sh) 1994-04-05
AU635752B2 (en) 1993-04-01
JP2999820B2 (ja) 2000-01-17
DE69007547D1 (de) 1994-04-28
WO1990014832A1 (en) 1990-12-13
JPH04500365A (ja) 1992-01-23
IL94619A0 (en) 1991-04-15
RU2032402C1 (ru) 1995-04-10
IE902011L (en) 1990-12-06
DK0404376T3 (da) 1994-05-24
HU207795B (en) 1993-06-28
KR0169487B1 (ko) 1999-01-15
CA1337279C (en) 1995-10-10
YU47950B (sh) 1996-07-24
CN1049101A (zh) 1991-02-13
IE65413B1 (en) 1995-10-18
PL164128B1 (pl) 1994-06-30
EP0404376B1 (de) 1994-03-23
EP0404376A2 (de) 1990-12-27
AU5829490A (en) 1991-01-07
HUT56490A (en) 1991-09-30
EP0404376A3 (de) 1991-06-05
CN1054507C (zh) 2000-07-19
IL94619A (en) 1995-01-24
KR920700032A (ko) 1992-02-19

Similar Documents

Publication Publication Date Title
DE69007547D1 (de) Gepufferte Metronidazolmittel zur intravaginalen Behandlung vaginaler Infektionen.
DE69739792D1 (de) Verfahren zur Behandlung von Augenerkrankungen
WO2006050303A3 (en) Intravaginal treatment of vaginal infections with metronidazole compositions
IE812025L (en) Composition for treating osteitis
EP1433485A3 (de) Urogenitale-Störungen Therapiesystem
FI954804A0 (fi) Ioneenipolymeerit matolääkkeinä eläimillä
ATE455545T1 (de) Medizinische zusammensetzungen zur intravesikalen behandlung von blasenkrebs
FR2542616B1 (fr) Composition pour le traitement des muqueuses a base d'un antibiotique et d'un hydrocolloide formateur de gel
RU2000108461A (ru) Вакцина против урогенитальных инфекций на основе вагинального суппозитория
EP0305744A3 (de) Chinolin-, Naphthyridin- und Benzoxazincarbonsäure-Derivate und ihre Verwendung als antibakterielle Mittel
ATE109978T1 (de) Verwendung von purpuromycin zur behandlung von vaginalinfektionen.
FR2742336B1 (fr) Collyre destine notamment au traitement de l'oeil sec
GB1538932A (en) Therapeutic method of treating mink infection and bovine mastitis by pseudomonas aeruginosa
RU2180241C2 (ru) Ранозаживляющее средство
EG19534A (en) Improved intravaginal treatment of viginal infections with buffered metronidazole compositions
UA33121A (uk) Спосіб лікування маститу у корів
FR2648458B1 (fr) Acide diallyloxyacetique et ses sels d'addition basiques, leur procede de preparation et leur application comme agent reticulant

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: MINNESOTA MINING AND MFG. CO., SAINT PAUL, MINN.,

8327 Change in the person/name/address of the patent owner

Owner name: MEDA AB, SOLNA, SE

8328 Change in the person/name/address of the agent

Representative=s name: MEISSNER, BOLTE & PARTNER GBR, 80538 MUENCHEN