YU47116B - Postupak za dobijanje novih n-supstituisanih benzimidazolskih derivata - Google Patents

Postupak za dobijanje novih n-supstituisanih benzimidazolskih derivata

Info

Publication number
YU47116B
YU47116B YU211087A YU211087A YU47116B YU 47116 B YU47116 B YU 47116B YU 211087 A YU211087 A YU 211087A YU 211087 A YU211087 A YU 211087A YU 47116 B YU47116 B YU 47116B
Authority
YU
Yugoslavia
Prior art keywords
carbon atoms
alkyl
halogen
alkoxy
substituted
Prior art date
Application number
YU211087A
Other languages
English (en)
Serbo-Croatian (sh)
Other versions
YU211087A (en
Inventor
R.A. Bergman
H. Bundgaard
P.L. Lindberg
G.E. Sunden
Original Assignee
Aktiebolaget Hassle
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE8604998A external-priority patent/SE8604998D0/xx
Priority claimed from SE8605551A external-priority patent/SE8605551D0/xx
Priority claimed from SE8704049A external-priority patent/SE8704049D0/xx
Application filed by Aktiebolaget Hassle filed Critical Aktiebolaget Hassle
Publication of YU211087A publication Critical patent/YU211087A/xx
Publication of YU47116B publication Critical patent/YU47116B/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
YU211087A 1986-11-21 1987-11-20 Postupak za dobijanje novih n-supstituisanih benzimidazolskih derivata YU47116B (sh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE8604998A SE8604998D0 (sv) 1986-11-21 1986-11-21 Novel pharmacological compounds
SE8605551A SE8605551D0 (sv) 1986-12-23 1986-12-23 Novel pharmacological compounds
SE8704049A SE8704049D0 (sv) 1987-10-16 1987-10-16 Novel pharmacological compounds

Publications (2)

Publication Number Publication Date
YU211087A YU211087A (en) 1988-12-31
YU47116B true YU47116B (sh) 1994-12-28

Family

ID=27355365

Family Applications (1)

Application Number Title Priority Date Filing Date
YU211087A YU47116B (sh) 1986-11-21 1987-11-20 Postupak za dobijanje novih n-supstituisanih benzimidazolskih derivata

Country Status (24)

Country Link
EP (3) EP0510719A1 (OSRAM)
JP (1) JPH02500744A (OSRAM)
KR (1) KR890700125A (OSRAM)
AT (1) ATE84032T1 (OSRAM)
AU (1) AU612129B2 (OSRAM)
DE (1) DE3783356T2 (OSRAM)
DK (1) DK365488D0 (OSRAM)
EG (1) EG18379A (OSRAM)
ES (1) ES2052603T3 (OSRAM)
FI (1) FI892454L (OSRAM)
GR (1) GR3007385T3 (OSRAM)
HU (1) HU204814B (OSRAM)
IE (2) IE61178B1 (OSRAM)
IL (1) IL84504A (OSRAM)
IS (1) IS1565B (OSRAM)
LV (1) LV10954B (OSRAM)
MY (1) MY101784A (OSRAM)
NO (1) NO173998C (OSRAM)
NZ (2) NZ222495A (OSRAM)
PL (1) PL157655B1 (OSRAM)
PT (1) PT86186B (OSRAM)
RU (1) RU2062778C1 (OSRAM)
WO (1) WO1988003921A1 (OSRAM)
YU (1) YU47116B (OSRAM)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8801907D0 (sv) * 1988-05-20 1988-05-20 Haessle Ab Novel pharmacological compounds
WO1990003373A1 (en) * 1988-09-20 1990-04-05 Hisamitsu Pharmaceutical Co., Inc. NOVEL DIBENZ[b,e]OXEPIN DERIVATIVES
SE8804629D0 (sv) * 1988-12-22 1988-12-22 Ab Haessle New therapeutically active compounds
EG19302A (en) * 1988-12-22 1994-11-30 Haessle Ab Compound with gastric acid inhibitory effect and process for its preparation
US5049674A (en) * 1989-12-20 1991-09-17 Aktiebolaget Hassle Therapeutically active fluoro substituted benzimidazoles
US5274099A (en) * 1989-12-20 1993-12-28 Aktiebolaget Hassle Therapeutically active fluoro substituted benzimidazoles
US4965269A (en) * 1989-12-20 1990-10-23 Ab Hassle Therapeutically active chloro substituted benzimidazoles
SE9002206D0 (sv) 1990-06-20 1990-06-20 Haessle Ab New compounds
EP0593463B1 (en) * 1990-06-20 1999-09-15 Astra Aktiebolag Dialkoxy-pyridinyl-benzimidazole derivatives, process for their preparation and their pharmaceutical use
ATE191213T1 (de) * 1990-10-17 2000-04-15 Takeda Chemical Industries Ltd Pyridin-derivate, verfahren zu deren herstellung und anwendung
SE9103776D0 (sv) * 1991-12-19 1991-12-19 Astra Ab New compounds
AU653681B2 (en) * 1992-05-21 1994-10-06 Otsuka Pharmaceutical Factory, Inc. Phosphonic diester derivative
WO1994026279A1 (en) * 1993-05-18 1994-11-24 The Upjohn Company Bisphosphonate esters for treating gastric disorders
US6875872B1 (en) 1993-05-28 2005-04-05 Astrazeneca Compounds
SE508669C2 (sv) * 1996-04-26 1998-10-26 Astra Ab Nytt förfarande
WO1998054172A1 (en) * 1997-05-30 1998-12-03 Dr. Reddy's Research Foundation Novel benzimidazole derivatives as antiulcer agents, process for their preparation and pharmaceutical compositions containing them
EP1051181B1 (en) * 1997-12-31 2004-03-17 The University Of Kansas Water soluble prodrugs of tertiary amine containing drugs and methods of making thereof
ZA9810765B (en) * 1998-05-28 1999-08-06 Ranbaxy Lab Ltd Stable oral pharmaceutical composition containing a substituted pyridylsulfinyl benzimidazole.
US20020103161A1 (en) 1999-12-17 2002-08-01 Manfred Weigele Novel heterocycles
US20040039027A1 (en) * 2000-10-12 2004-02-26 Keiji Kamiyama Benzimidazole compounds, process for producing the same and use thereof
EP1437352A4 (en) * 2001-09-25 2004-12-08 Takeda Chemical Industries Ltd BENZIMIDAZOLE COMPOUND, METHOD FOR THE PRODUCTION AND USE THEREOF
DK1556371T3 (da) * 2002-07-19 2006-08-21 Winston Pharmaceuticals Llc Benzimidazol-derivater og deres anvendelse som prodrugs for protonpumpe-inhibitorer
GB0400781D0 (en) * 2004-01-14 2004-02-18 Novartis Ag Organic compounds
AU2005276591B2 (en) * 2004-08-27 2011-03-31 Laboratorios Del Dr. Esteve, S.A. Sigma receptor inhibitors
DK1913009T3 (da) * 2005-07-28 2010-08-16 Intervet Int Bv Nye benzimidazol(thio)carbamater med antiparasitisk virkning samt syntese heraf
US10272070B2 (en) 2014-10-14 2019-04-30 The Board of Trustees of the Leland Stanford Junio r University Method for treating neurodegenerative diseases
JP6837486B2 (ja) 2015-12-15 2021-03-03 ザ ボード オブ トラスティーズ オブ ザ リーランド スタンフォード ジュニア ユニバーシティＴｈｅ Ｂｏａｒｄ ｏｆ Ｔｒｕｓｔｅｅｓ ｏｆ ｔｈｅ Ｌｅｌａｎｄ Ｓｔａｎｆｏｒｄ Ｊｕｎｉｏｒ Ｕｎｉｖｅｒｓｉｔｙ 加齢に関連する認知障害及び神経炎症を予防及び／又は治療する方法
BR112021002165A2 (pt) 2018-08-06 2021-05-04 The Board Of Trustees Of The Leland Stanford Junior University composto, composição farmacêutica, e, métodos para tratar uma doença neurodegenerativa e deficiência cognitiva associada ao envelhecimento e neuroinflamação
JP7409383B2 (ja) * 2019-08-20 2024-01-09 小野薬品工業株式会社 Ｓ１ｐ５受容体作動活性を有する化合物の塩および結晶形

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE418966B (sv) 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
SE416649B (sv) 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
IN148930B (OSRAM) 1977-09-19 1981-07-25 Hoffmann La Roche
SE7804231L (sv) 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
JPS5836312B2 (ja) * 1978-08-21 1983-08-08 日本電信電話株式会社 通信用平衡ケ−ブル線路の障害位置測定方式
JPS5687818A (en) * 1979-12-19 1981-07-16 Ishikawajima Harima Heavy Ind Co Ltd Reflex type position detector
US4359465A (en) * 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
CH644116A5 (de) 1980-08-21 1984-07-13 Hoffmann La Roche Imidazolderivate.
JPS57137860A (en) * 1981-02-20 1982-08-25 Sumitomo Electric Ind Ltd Optical tachometer
JPS5999597A (ja) * 1982-11-30 1984-06-08 株式会社東芝 光学測定装置
SE8300736D0 (sv) * 1983-02-11 1983-02-11 Haessle Ab Novel pharmacologically active compounds
JPS6020051U (ja) * 1983-07-19 1985-02-12 三洋電機株式会社 カセツト収納装置
AU568441B2 (en) * 1984-09-24 1987-12-24 Upjohn Company, The 2-(pyridylalkenesulfinyl) benzimidazole derivatives
IL76839A (en) * 1984-10-31 1988-08-31 Byk Gulden Lomberg Chem Fab Picoline derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
SE8505112D0 (sv) * 1985-10-29 1985-10-29 Haessle Ab Novel pharmacological compounds

Also Published As

Publication number Publication date
NO173998C (no) 1994-03-02
AU612129B2 (en) 1991-07-04
NO883229L (no) 1988-09-16
DK365488A (da) 1988-07-01
HU204814B (en) 1992-02-28
HUT51269A (en) 1990-04-28
KR890700125A (ko) 1989-03-02
NZ222495A (en) 1991-04-26
RU2062778C1 (ru) 1996-06-27
GR3007385T3 (OSRAM) 1993-07-30
PT86186B (pt) 1990-08-31
EP0279149A2 (en) 1988-08-24
DK365488D0 (da) 1988-07-01
ES2052603T3 (es) 1994-07-16
EP0279149A3 (en) 1988-08-31
LV10954B (en) 1996-08-20
EP0510719A1 (en) 1992-10-28
IE61178B1 (en) 1994-10-05
EP0279149B1 (en) 1992-12-30
FI892454A0 (fi) 1989-05-19
YU211087A (en) 1988-12-31
FI892454A7 (fi) 1989-05-19
PL157655B1 (pl) 1992-06-30
MY101784A (en) 1992-01-17
IE873125L (en) 1988-05-21
ATE84032T1 (de) 1993-01-15
JPH02500744A (ja) 1990-03-15
NO883229D0 (no) 1988-07-20
AU8330287A (en) 1988-06-16
EG18379A (en) 1992-11-30
NZ234564A (en) 1991-04-26
LV10954A (lv) 1995-12-20
IE940326L (en) 1988-05-21
DE3783356D1 (de) 1993-02-11
FI892454L (fi) 1989-05-19
IS1565B (is) 1994-12-13
WO1988003921A1 (en) 1988-06-02
PL268927A1 (en) 1989-01-23
EP0332647A1 (en) 1989-09-20
NO173998B (no) 1993-11-22
IS3284A7 (is) 1988-05-22
PT86186A (en) 1987-12-01
DE3783356T2 (de) 1993-04-15
IL84504A (en) 1994-10-07

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