YU45942B - Postupak za dobivanje hidrohlorida 2(n-benzil-n-metilamino)-etil-metil-1,4-dihidro-2,6-dimetil-4-(3-nitrofenil)-3,5-piridin-dikarbok sil - Google Patents

Postupak za dobivanje hidrohlorida 2(n-benzil-n-metilamino)-etil-metil-1,4-dihidro-2,6-dimetil-4-(3-nitrofenil)-3,5-piridin-dikarbok sil

Info

Publication number
YU45942B
YU45942B YU66687A YU66687A YU45942B YU 45942 B YU45942 B YU 45942B YU 66687 A YU66687 A YU 66687A YU 66687 A YU66687 A YU 66687A YU 45942 B YU45942 B YU 45942B
Authority
YU
Yugoslavia
Prior art keywords
methyl
benzyl
ethyl
sil
nitrophenyl
Prior art date
Application number
YU66687A
Other languages
English (en)
Other versions
YU66687A (en
Inventor
A. Salimbeni
E. Manghisi
Original Assignee
Instituto Luso Farmaco D'italia S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Instituto Luso Farmaco D'italia S.P.A. filed Critical Instituto Luso Farmaco D'italia S.P.A.
Publication of YU66687A publication Critical patent/YU66687A/xx
Publication of YU45942B publication Critical patent/YU45942B/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

POSTUPAK ZA DOBIVANJE HIDROHLORIDA 2(N-BENZIL-N-METILAMINO)-ETIL-METIL-1,4-DIHIDRO-2,6-DIMETIL-4-(3-NITROFENIL)-3,5-PIRIDIN-DIKARBOK SIL, formule I naznačen time, što reaguju 3-nitrobenzaldehid, 2-(N-metil-amino)-etil acetoacetat i metil-3-aminokrotonat u ekvimolarnim odnosima u izopropanolu tokom 6 časova na temperaturi refluksa i dobiveno jedinjenje formule II reaguje sa benzil halidom u toluolu na temperturi refluksa u prisustvu alkalnog karbonata. Prijava sadrži još 1 zahtev.
YU66687A 1986-05-05 1987-04-13 Postupak za dobivanje hidrohlorida 2(n-benzil-n-metilamino)-etil-metil-1,4-dihidro-2,6-dimetil-4-(3-nitrofenil)-3,5-piridin-dikarbok sil YU45942B (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT20305/86A IT1204336B (it) 1986-05-05 1986-05-05 Processo per la preparazione di 2-(n-benzil-n-metilammino)-etil-metil1,4-diidro-2,6-dimetil-4-(3-nitrofenil)-3,5-piridin-dicarbossilato cloridrato

Publications (2)

Publication Number Publication Date
YU66687A YU66687A (en) 1988-08-31
YU45942B true YU45942B (sh) 1992-09-07

Family

ID=11165586

Family Applications (1)

Application Number Title Priority Date Filing Date
YU66687A YU45942B (sh) 1986-05-05 1987-04-13 Postupak za dobivanje hidrohlorida 2(n-benzil-n-metilamino)-etil-metil-1,4-dihidro-2,6-dimetil-4-(3-nitrofenil)-3,5-piridin-dikarbok sil

Country Status (4)

Country Link
EP (1) EP0245680A3 (sh)
JP (1) JPS62289564A (sh)
IT (1) IT1204336B (sh)
YU (1) YU45942B (sh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04211060A (ja) * 1990-03-07 1992-08-03 Tokawa Tetsuo ２，６−ジメチル−４−（ｍ−ニトロフェニル）−１，４−ジヒドロピリジン−３，５−ジカルボン酸−３−メチルエステル−５−β−（Ｎ−ベンジル−Ｎ−メチルアミノ）エチルエステルの新規製造方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU557175B2 (en) * 1982-10-15 1986-12-11 Kyowa Hakko Kogyo Co. Ltd. 2,6-dimethyl-4-(3-nitro phenyl)-1,4-dihydro pyridine-3,5- dicarboxylic acid esters

Also Published As

Publication number Publication date
JPS62289564A (ja) 1987-12-16
YU66687A (en) 1988-08-31
EP0245680A3 (en) 1988-04-20
IT1204336B (it) 1989-03-01
EP0245680A2 (en) 1987-11-19
IT8620305A0 (it) 1986-05-05

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