YU43199A - Postupak za dobijanje trovafloksacin kiselinskih soli - Google Patents

Postupak za dobijanje trovafloksacin kiselinskih soli

Info

Publication number
YU43199A
YU43199A YU43199A YU43199A YU43199A YU 43199 A YU43199 A YU 43199A YU 43199 A YU43199 A YU 43199A YU 43199 A YU43199 A YU 43199A YU 43199 A YU43199 A YU 43199A
Authority
YU
Yugoslavia
Prior art keywords
acid
acid salts
trovafloxacine
salts
preparing
Prior art date
Application number
YU43199A
Other languages
English (en)
Inventor
Timothy Norris
Peter Robert Rose
Keith Michael De Vries
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of YU43199A publication Critical patent/YU43199A/sh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cephalosporin Compounds (AREA)
  • Indole Compounds (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Trovafloksacin kiselinske soli se dobijaju hidrolizom imin intermedijara korišćenjem mineralnih kiselina ali nisu ograničene na, metansulfonsku kiselinu, etansulfonsku kiselinu, benzensulfonsku kiselinu, azotnu kiselinu, sumpornu kiselinu, fosfornu kiselinu, hlorovodoničnu kiselinu, bromovodoničnu kiselinu, vinsku kiselinu, limunsku kiselinu, sirćetnu kiselinu i maleinsku kiselinu. Trovafloksacin kiselinske soli su korisne kao antibiotski agensi.[Trovafloxacine acid salts are obtained by hydrolise of imune intermedites by using mineral acids including, but not limited to, methansulphonic acid, ethansulphonic acid, benzene sulphonic acid, nitrogen acid, sulphure acid, phospore acid, chlorohydrogen acid, bromohydrogen acid, wine acid, citric acid, acetic acid and maleine acid. Trovafloxacine acid salts are useful as antibiotic agents.
YU43199A 1998-09-03 1999-09-02 Postupak za dobijanje trovafloksacin kiselinskih soli YU43199A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9894498P 1998-09-03 1998-09-03

Publications (1)

Publication Number Publication Date
YU43199A true YU43199A (sh) 2002-11-15

Family

ID=22271674

Family Applications (1)

Application Number Title Priority Date Filing Date
YU43199A YU43199A (sh) 1998-09-03 1999-09-02 Postupak za dobijanje trovafloksacin kiselinskih soli

Country Status (40)

Country Link
US (1) US6359137B1 (sh)
EP (1) EP0989119A1 (sh)
JP (1) JP3354526B2 (sh)
KR (1) KR20000022858A (sh)
CN (1) CN1248580A (sh)
AP (1) AP1118A (sh)
AR (1) AR021475A1 (sh)
AU (1) AU761035B2 (sh)
BG (1) BG103703A (sh)
BR (1) BR9904082A (sh)
CA (1) CA2281244C (sh)
CO (1) CO5251466A1 (sh)
EA (1) EA002340B1 (sh)
EE (1) EE04118B1 (sh)
GE (1) GEP20022785B (sh)
GT (1) GT199900142A (sh)
HN (1) HN1999000141A (sh)
HR (1) HRP990274A2 (sh)
HU (1) HUP9902967A3 (sh)
ID (1) ID23718A (sh)
IL (1) IL131614A0 (sh)
IN (1) IN191583B (sh)
IS (1) IS5168A (sh)
MA (1) MA24966A1 (sh)
MY (1) MY130800A (sh)
NO (1) NO994261L (sh)
NZ (1) NZ337605A (sh)
OA (1) OA11152A (sh)
PA (1) PA8481001A1 (sh)
PE (1) PE20001026A1 (sh)
PL (1) PL335246A1 (sh)
SG (1) SG74748A1 (sh)
SK (1) SK116599A3 (sh)
SV (1) SV1999000144A (sh)
TN (1) TNSN99164A1 (sh)
TR (1) TR199902138A2 (sh)
TW (1) TW520369B (sh)
UY (1) UY25686A1 (sh)
YU (1) YU43199A (sh)
ZA (1) ZA995630B (sh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104892507B (zh) * 2015-05-26 2018-08-28 徐州天意动物药业股份有限公司 水溶性甲磺酸沙拉沙星及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5164402A (en) * 1989-08-16 1992-11-17 Pfizer Inc Azabicyclo quinolone and naphthyridinone carboxylic acids
BR9408490A (pt) * 1994-01-18 1997-08-26 Pfizer Processo e intermediários para a preparação de sais do ácido nafftiridonocarboxílico
DK0789697T3 (da) * 1995-06-06 1998-10-19 Pfizer Krystalform af vandfrit 7-([1alfa, 5alfa, 6alfa,]-6-amino-3-azabicyclo[3.1.0]hex-3-yl)-6-fluor-1-(2,4-difluorphenyl)-1,4-d
JPH0912546A (ja) * 1995-06-23 1997-01-14 Chisso Corp アザビシクロ環化合物および製造方法
JPH0912547A (ja) * 1995-06-23 1997-01-14 Chisso Corp ニューキノロン系化合物中間体の製造方法
KR100343909B1 (ko) * 1995-08-29 2003-04-10 화이자 인코포레이티드 트로바플록사신의쯔비터이온형태
PA8464701A1 (es) * 1998-01-16 2000-09-29 Pfizer Prod Inc Procedimiento e intermedios para preparar naftiridonas
US6184380B1 (en) * 1999-01-25 2001-02-06 Pfizer Inc. Process for preparing naphthyridones and intermediates

Also Published As

Publication number Publication date
EA199900708A2 (ru) 2000-04-24
AR021475A1 (es) 2002-07-24
TR199902138A2 (xx) 2000-04-21
PL335246A1 (en) 2000-03-13
AP1118A (en) 2002-11-21
NO994261D0 (no) 1999-09-02
AU761035B2 (en) 2003-05-29
CN1248580A (zh) 2000-03-29
CA2281244A1 (en) 2000-03-03
MY130800A (en) 2007-07-31
TW520369B (en) 2003-02-11
HU9902967D0 (en) 1999-10-28
CO5251466A1 (es) 2003-02-28
MA24966A1 (fr) 2000-04-01
HN1999000141A (es) 2000-06-19
JP3354526B2 (ja) 2002-12-09
UY25686A1 (es) 2000-03-31
PE20001026A1 (es) 2000-10-11
EA002340B1 (ru) 2002-04-25
AU4482699A (en) 2000-03-16
NZ337605A (en) 2001-03-30
EP0989119A1 (en) 2000-03-29
BR9904082A (pt) 2000-09-12
CA2281244C (en) 2003-05-20
IN191583B (sh) 2003-12-06
EE04118B1 (et) 2003-08-15
EA199900708A3 (ru) 2000-08-28
SG74748A1 (en) 2000-08-22
ID23718A (id) 2000-05-11
US6359137B1 (en) 2002-03-19
HRP990274A2 (en) 2000-10-31
TNSN99164A1 (fr) 2005-11-10
AP9901667A0 (en) 1999-12-31
JP2000086658A (ja) 2000-03-28
SK116599A3 (en) 2000-05-16
IS5168A (is) 2000-03-04
BG103703A (bg) 2001-08-31
SV1999000144A (es) 2000-09-05
HUP9902967A2 (hu) 2000-05-28
NO994261L (no) 2000-03-06
KR20000022858A (ko) 2000-04-25
OA11152A (en) 2003-04-17
EE9900457A (et) 2000-04-17
GEP20022785B (en) 2002-09-25
IL131614A0 (en) 2001-01-28
PA8481001A1 (es) 2000-09-29
HUP9902967A3 (en) 2000-11-28
GT199900142A (es) 2001-02-15
ZA995630B (en) 2001-03-01

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