YU42995B - Process for preparing new sulfonamides - Google Patents

Process for preparing new sulfonamides

Info

Publication number
YU42995B
YU42995B YU8/81A YU881A YU42995B YU 42995 B YU42995 B YU 42995B YU 8/81 A YU8/81 A YU 8/81A YU 881 A YU881 A YU 881A YU 42995 B YU42995 B YU 42995B
Authority
YU
Yugoslavia
Prior art keywords
lower alkyl
aryl
preparing new
new sulfonamides
aralkenyl
Prior art date
Application number
YU8/81A
Other languages
English (en)
Other versions
YU881A (en
Inventor
E Witte
H P Wolff
K Stegmeier
E Roesch
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of YU881A publication Critical patent/YU881A/xx
Publication of YU42995B publication Critical patent/YU42995B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Devices That Are Associated With Refrigeration Equipment (AREA)
YU8/81A 1980-01-07 1981-01-06 Process for preparing new sulfonamides YU42995B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803000377 DE3000377A1 (de) 1980-01-07 1980-01-07 Neue sulfonamide, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
YU881A YU881A (en) 1983-10-31
YU42995B true YU42995B (en) 1989-02-28

Family

ID=6091629

Family Applications (1)

Application Number Title Priority Date Filing Date
YU8/81A YU42995B (en) 1980-01-07 1981-01-06 Process for preparing new sulfonamides

Country Status (22)

Country Link
US (1) US4443477A (da)
EP (1) EP0031954B1 (da)
JP (1) JPS56100757A (da)
AT (1) ATE6641T1 (da)
AU (1) AU538993B2 (da)
CA (1) CA1241341A (da)
CS (1) CS238611B2 (da)
DD (1) DD157190A5 (da)
DE (2) DE3000377A1 (da)
ES (1) ES498308A0 (da)
FI (1) FI73667C (da)
GR (1) GR72486B (da)
HK (1) HK68887A (da)
IE (1) IE50657B1 (da)
IL (1) IL61834A (da)
PH (1) PH18739A (da)
PL (1) PL127050B1 (da)
PT (1) PT72305B (da)
SG (1) SG2387G (da)
SU (1) SU1088664A3 (da)
YU (1) YU42995B (da)
ZA (1) ZA8132B (da)

Families Citing this family (62)

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DE3535167A1 (de) * 1985-10-02 1987-04-09 Boehringer Mannheim Gmbh Neue sulfonyl-phenyl(alkyl)amine, verfahren zu ihrer herstellung sowie arzneimittel
US4689182A (en) * 1985-12-20 1987-08-25 Warner-Lambert Company Benzoic acid and benzoic acid ester derivatives having anti-inflammatory and analgesic activity
FR2598412B1 (fr) * 1986-03-12 1988-10-21 Sanofi Sa Nouveaux derives de diarylcetones et leurs procedes de preparation et les compositions pharmaceutiques les contenant
IL83230A (en) * 1986-08-06 1992-06-21 Tanabe Seiyaku Co Phenoxyacetic acid derivatives,their preparation and pharmaceutical compositions containing them
DE3629929A1 (de) * 1986-09-03 1988-03-10 Thomae Gmbh Dr K Neue sulfonamido-aethylverbindungen, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
AU600992B2 (en) * 1986-10-28 1990-08-30 Smith Kline & French Laboratories Limited Tetrahydroisoquinolin-2-yl derivatives of carboxylic acids
GB8708233D0 (en) * 1987-04-07 1987-05-13 Smith Kline French Lab Pharmaceutically active compounds
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CA1294974C (en) * 1987-05-08 1992-01-28 Sanji Hagishita Bicyclic sulfonamide derivatives and process therefor
US4752616A (en) * 1987-06-29 1988-06-21 E. R. Squibb & Sons, Inc. Arylthioalkylphenyl carboxylic acids, compositions containing same and method of use
GB8717374D0 (en) * 1987-07-22 1987-08-26 Smith Kline French Lab Pharmaceutically active compounds
US4752613A (en) * 1987-08-03 1988-06-21 E. R. Squibb & Sons, Inc. Sulphonamidothienylcarboxylic acid compounds
US4783473A (en) * 1987-09-02 1988-11-08 E. R. Squibb & Sons, Inc. Geminally substituted cyclic ether carboxylic acids, derivatives thereof, compositions containing same and method of use
US4931460A (en) * 1987-09-17 1990-06-05 E. R. Squibb & Sons, Inc. Post-ischemic myocardial dysfunction using thromboxane A2 antagonists
JPH01175962A (ja) * 1987-12-28 1989-07-12 Tanabe Seiyaku Co Ltd フェニル酢酸誘導体
DE68909958D1 (de) * 1988-01-19 1993-11-25 Tanabe Seiyaku Co Phenoxyessigsäure-Derivate, ihre Herstellung, pharmazeutische Zusammensetzungen, die sie enthalten, und deren Verwendung.
US5066480A (en) * 1988-04-11 1991-11-19 E. R. Squibb & Sons, Inc. Method of preventing or reducing adverse reactions to protamine using a thromboxane a2 receptor antagonist
DE3819052A1 (de) * 1988-06-04 1989-12-07 Basf Ag Neue sulfonamid-derivate, ihre herstellung und verwendung
DE3829455A1 (de) * 1988-08-31 1990-03-15 Boehringer Mannheim Gmbh Sulfonamidoalkyl-cyclohexan-verbindungen, verfahren zu ihrer herstellung sowie arzneimittel
US4925873A (en) * 1988-09-01 1990-05-15 E. R. Squibb & Sons, Inc. Method of treating skin injuries using thromboxane A2 receptor antagonists
US5280043A (en) * 1988-10-10 1994-01-18 Smith Kline & French Laboratories Ltd. Sulphonamido containing phenylalkanoic acids as thromboxane A2 antagonists
GB8823731D0 (en) * 1988-10-10 1988-11-16 Smith Kline French Lab Biologically active compounds
US4959383A (en) * 1988-10-31 1990-09-25 E. R. Squibb & Sons, Inc. Phenylsulfone alkenoic acids, derivatives thereof, compositions containing same and method of use
US5070099A (en) * 1988-10-31 1991-12-03 E. R. Squibb & Sons, Inc. Arylthioalkylphenyl carboxylic acids, derivatives thereof, compositions containing same method of use
US5006542A (en) * 1988-10-31 1991-04-09 E. R. Squibb & Sons, Inc. Arylthioalkylphenyl carboxylic acids, derivatives thereof, compositions containing same and method of use
US5106991A (en) * 1989-06-02 1992-04-21 E. R. Squibb & Sons, Inc. Geminally substituted thiaheterocyclic carboxylic acids and derivatives thereof
US4975452A (en) * 1989-06-02 1990-12-04 E. R. Squibb & Sons, Inc. Geminally substituted thiaheterocyclic carboxylic acids and derivatives thereof
US5025025A (en) * 1989-06-28 1991-06-18 Ciba-Geigy Corporation (Arylsulfonamido- and pyridyl-)-substituted carboxylic acids and derivatives thereof and use for suppressing thromboxane activity
US5153214A (en) * 1989-06-28 1992-10-06 Ciba-Geigy Corporation Certain (arylsulfonamido- and imidazolyl-)-substituted carboxylic acids and derivatives thereof and use for suppressing thromboxane activity
DE4010536A1 (de) * 1990-04-02 1991-10-10 Boehringer Mannheim Gmbh Pharmazeutische waessrige loesung von 4-(2-(benzolsulfonylamino)-ethyl)-phenoxyessigsaeure
FR2665440B1 (fr) * 1990-07-31 1994-02-04 Lipha Nouveaux cycloalkylsulfonamides substitues, procedes de preparation et medicaments les contenant.
US5189211A (en) * 1990-08-01 1993-02-23 Taisho Pharmaceutical Co., Ltd. Sulfonamide derivatives
US5409959A (en) * 1991-01-29 1995-04-25 Genelabs Incorporated Antithrombotic treatment with calix(n)arene compounds
DE4109735A1 (de) * 1991-03-25 1992-10-01 Boehringer Mannheim Gmbh Neue sulfonamide, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten
US5280034A (en) * 1991-08-23 1994-01-18 E. R. Squibb & Sons, Inc. Bis-heterocyclic prostaglandin analogs
US5827868A (en) * 1991-10-07 1998-10-27 E. R. Squibb & Sons, Inc. Prostaglandin analogs
TW219358B (da) * 1991-12-20 1994-01-21 Hokuriku Pharmaceutical
GB9220137D0 (en) * 1992-09-23 1992-11-04 Pfizer Ltd Therapeutic agents
JPH0753505A (ja) * 1992-10-01 1995-02-28 Hokuriku Seiyaku Co Ltd ベンゼンスルホンアミド誘導体及びその用途
CA2244785C (en) * 1996-02-22 2003-12-02 Tularik, Inc. Pentafluorobenzenesulfonamides and analogs
DK0939627T3 (da) * 1996-07-19 2003-10-13 Tularik Inc Pentaflourbenzensulfonamider og analoger
GB9702194D0 (en) * 1997-02-04 1997-03-26 Lilly Co Eli Sulphonide derivatives
FR2760235B1 (fr) * 1997-02-28 1999-04-09 Adir Nouveaux derives de benzenesulfonylamine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
UA67754C2 (uk) * 1997-10-10 2004-07-15 Пфайзер, Інк. Агоністи простагландину, фармацевтична композиція на їх основі (варіанти), спосіб нарощення та збереження кісткової маси у хребетних та спосіб лікування (варіанти)
US6693137B1 (en) * 1998-07-31 2004-02-17 Eli Lilly And Company Sulphonamide derivatives
CN1413190A (zh) 1999-12-22 2003-04-23 辉瑞产品公司 治疗骨质疏松的ep4受体选择性激动剂
US6822001B2 (en) 2000-11-03 2004-11-23 Tularik Inc. Combination therapy using pentafluorobenzenesulfonamides and antineoplastic agents
US20050250854A1 (en) * 2000-11-03 2005-11-10 Amgen Inc. Combination therapy using pentafluorobenzenesulfonamides and antineoplastic agents
MX2007004862A (es) * 2004-10-29 2007-05-09 Astrazeneca Ab Nuevos derivados de sulfonamida como moduladores del receptor de glucocorticoides para el tratamiento de enfermedades inflamatorias.
TW200829578A (en) 2006-11-23 2008-07-16 Astrazeneca Ab Chemical compounds 537
JO2754B1 (en) 2006-12-21 2014-03-15 استرازينكا ايه بي Amylendazoleil derivatives for the treatment of glucocorticoid-mediated disorders
AU2008244306A1 (en) * 2007-04-27 2008-11-06 Tibotec Pharmaceuticals Ltd. Methods for the preparation of N-isobutyl-N-(2-hydroxy-3-amino-4-phenylbutyl)-p-nitrobenzenesulfonylamide derivatives
US20100080786A1 (en) 2008-05-20 2010-04-01 Markus Berger Phenyl or Pyridinyl Substituted Indazoles Derivatives
CA2729767A1 (en) * 2008-07-07 2010-01-14 Fasgen, Inc. Novel compounds, pharmaceutical compositions containing same, methods of use for same, and methods for preparing same
CN110776447A (zh) 2012-09-20 2020-02-11 坦普尔大学 取代的烷基二芳基衍生物、制备方法和用途
EP3142655B1 (en) 2014-05-16 2020-12-02 Cumberland Pharmaceuticals Inc. Compositions and methods of treating cardiac fibrosis with ifetroban
WO2017004040A1 (en) 2015-06-30 2017-01-05 Cumberland Pharmaceuticals, Inc. Thromboxane receptor antagonists in aerd/asthma
WO2017023912A1 (en) 2015-08-03 2017-02-09 Temple University - Of The Commonwealth System Of Higher Education 2,4,6-trialkoxystryl aryl sulfones, sulfonamides and carboxamides, and methods of preparation and use
US10064845B2 (en) 2016-05-11 2018-09-04 Cumberland Pharmaceuticals, Inc. Compositions and methods of treating muscular dystrophy with thromboxane-A2 receptor antagonists

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BE542184A (da) * 1954-10-21
US3027405A (en) * 1959-07-29 1962-03-27 Geigy Chem Corp Nu-(alkylarylsulfonyl)-amino acids and salts thereof
US3991106A (en) * 1974-09-13 1976-11-09 Merck & Co., Inc. 16-Ethers of 8-aza-9-dioxothia-11,12-seco-prostaglandins
DK148576A (da) * 1975-04-18 1976-10-19 Boehringer Mannheim Gmbh Fenylalkankarbonsyrederivater og fremgangsmade til deres fremstilling
US4112236A (en) * 1977-04-04 1978-09-05 Merck & Co., Inc. Interphenylene 8-aza-9-dioxothia-11,12-secoprostaglandins
GB1572201A (en) * 1977-04-05 1980-07-23 Bristol Myers Co Cephalosporins
DE2809377A1 (de) * 1978-03-04 1979-09-13 Boehringer Mannheim Gmbh Phenoxyalkylcarbonsaeure-derivate, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
DE3000519A1 (de) * 1979-02-01 1980-08-14 Byk Gulden Lomberg Chem Fab Sulfonamido-alkansaeuren, ihre verwendung und herstellung sowie sie enthaltende arzneimittel

Also Published As

Publication number Publication date
EP0031954A2 (de) 1981-07-15
PT72305B (de) 1981-12-17
IL61834A (en) 1984-06-29
AU538993B2 (en) 1984-09-06
FI73667C (fi) 1987-11-09
AU6597481A (en) 1981-07-16
PL127050B1 (en) 1983-09-30
CA1241341A (en) 1988-08-30
DD157190A5 (de) 1982-10-20
PH18739A (en) 1985-09-16
ES8200655A1 (es) 1981-12-01
JPS6352625B2 (da) 1988-10-19
CS238611B2 (en) 1985-12-16
ES498308A0 (es) 1981-12-01
SG2387G (en) 1987-11-13
IE50657B1 (en) 1986-06-11
HK68887A (en) 1987-10-02
SU1088664A3 (ru) 1984-04-23
GR72486B (da) 1983-11-14
PL229072A1 (da) 1982-04-26
PT72305A (de) 1981-02-01
ZA8132B (en) 1982-02-24
DE3067068D1 (en) 1984-04-19
DE3000377A1 (de) 1981-07-09
FI804085L (fi) 1981-07-08
YU881A (en) 1983-10-31
IL61834A0 (en) 1981-01-30
EP0031954B1 (de) 1984-03-14
JPS56100757A (en) 1981-08-12
ATE6641T1 (de) 1984-03-15
IE810006L (en) 1981-07-07
FI73667B (fi) 1987-07-31
EP0031954A3 (en) 1981-11-11
US4443477A (en) 1984-04-17

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