YU293181A - Process for obtaining new 6-alpha-methy-hydrocortisone derivatives - Google Patents

Process for obtaining new 6-alpha-methy-hydrocortisone derivatives

Info

Publication number
YU293181A
YU293181A YU02931/81A YU293181A YU293181A YU 293181 A YU293181 A YU 293181A YU 02931/81 A YU02931/81 A YU 02931/81A YU 293181 A YU293181 A YU 293181A YU 293181 A YU293181 A YU 293181A
Authority
YU
Yugoslavia
Prior art keywords
alpha
methy
obtaining new
hydrocortisone derivatives
hydrocortisone
Prior art date
Application number
YU02931/81A
Other languages
English (en)
Inventor
K Annen
K Petzoldt
H Laurent
R Wiechert
H Hofmeister
H Wendt
M Albring
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of YU293181A publication Critical patent/YU293181A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00—Preparation of steroids
    • C12P33/06—Hydroxylating
    • C12P33/08—Hydroxylating at 11 position
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Cephalosporin Compounds (AREA)
  • Fats And Perfumes (AREA)
  • Anti-Oxidant Or Stabilizer Compositions (AREA)
  • Lubricants (AREA)
YU02931/81A 1980-12-23 1981-12-14 Process for obtaining new 6-alpha-methy-hydrocortisone derivatives YU293181A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3049400 1980-12-23

Publications (1)

Publication Number Publication Date
YU293181A true YU293181A (en) 1983-10-31

Family

ID=6120491

Family Applications (5)

Application Number Title Priority Date Filing Date
YU02931/81A YU293181A (en) 1980-12-23 1981-12-14 Process for obtaining new 6-alpha-methy-hydrocortisone derivatives
YU01020/83A YU102083A (en) 1980-12-23 1983-05-09 Process for obtaining new 6-alpha-methyl-hydrocortisone derivatives
YU01032/83A YU103283A (en) 1980-12-23 1983-05-10 Process for obtaining new 6-alpha-methyl-hydrocortisone derivatives
YU01031/83A YU103183A (en) 1980-12-23 1983-05-10 Process for obtaining new 6-alpha-methyl-hydrocortisone derivatives
YU01033/83A YU103383A (en) 1980-12-23 1983-05-10 Process for obtaining new 6-alpha-methyl-hydrocortisone derivatives

Family Applications After (4)

Application Number Title Priority Date Filing Date
YU01020/83A YU102083A (en) 1980-12-23 1983-05-09 Process for obtaining new 6-alpha-methyl-hydrocortisone derivatives
YU01032/83A YU103283A (en) 1980-12-23 1983-05-10 Process for obtaining new 6-alpha-methyl-hydrocortisone derivatives
YU01031/83A YU103183A (en) 1980-12-23 1983-05-10 Process for obtaining new 6-alpha-methyl-hydrocortisone derivatives
YU01033/83A YU103383A (en) 1980-12-23 1983-05-10 Process for obtaining new 6-alpha-methyl-hydrocortisone derivatives

Country Status (26)

Country Link
US (1) US4912098A (xx)
EP (1) EP0054786B1 (xx)
JP (1) JPS57167999A (xx)
AT (1) ATE12237T1 (xx)
AU (1) AU548999B2 (xx)
BG (2) BG38337A3 (xx)
CA (1) CA1185234A (xx)
CS (5) CS221781A2 (xx)
DD (2) DD202580A5 (xx)
DE (1) DE3169460D1 (xx)
DK (1) DK159324C (xx)
ES (3) ES8307896A1 (xx)
FI (1) FI72729C (xx)
GB (1) GB2089809B (xx)
GR (1) GR76975B (xx)
HU (1) HU186460B (xx)
IE (1) IE52511B1 (xx)
IL (1) IL64614A (xx)
NO (1) NO156409C (xx)
PH (1) PH17637A (xx)
PL (5) PL234367A1 (xx)
PT (1) PT74183B (xx)
RO (1) RO83669B (xx)
SU (2) SU1255053A3 (xx)
YU (5) YU293181A (xx)
ZA (1) ZA818907B (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3133081A1 (de) * 1981-08-18 1983-03-10 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue 6(alpha)-methylprednisolon-derivate, ihre herstellung und verwendung
DE3227312A1 (de) * 1982-07-19 1984-01-19 Schering AG, 1000 Berlin und 4709 Bergkamen Neue 6,16-dimethylkortikoide, ihre herstellung und verwendung
DE3243482A1 (de) * 1982-11-22 1984-05-24 Schering AG, 1000 Berlin und 4709 Bergkamen Neue 6(alpha)-methylkortikoide, ihre herstellung und verwendung
DE3427486A1 (de) * 1984-07-23 1986-01-30 Schering AG, Berlin und Bergkamen, 1000 Berlin Verfahren zur herstellung von 6(alpha)-methylsteroiden
CN102401624B (zh) * 2010-09-10 2014-07-16 珠海格力电器股份有限公司 步进电机行程位置检测装置及检测控制方法
CN102964414A (zh) * 2012-12-14 2013-03-13 中国科学院上海有机化学研究所 17位甾体羧酸酯的合成方法
EP3006453A1 (en) * 2014-10-08 2016-04-13 Cosmo Technologies Ltd. 17alpha-monoesters and 17alpha,21-diesters of cortexolone for use in the treatment of tumors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3141876A (en) * 1956-08-02 1964-07-21 Upjohn Co 3-keto-6-methyl-4-pregnene-3, 20-diones and a method for the production thereof
US3176032A (en) * 1958-04-18 1965-03-30 Syntex Corp 17alpha, 21-diacyloxy derivatives of 6alpha-methyl-delta1, 4-pregnadien-3, 20-dione and of 6alpha-methyl-delta4-pregnen-3, 20-dione
JPS6040439B2 (ja) * 1978-03-29 1985-09-11 大正製薬株式会社 ヒドロコルチゾン誘導体
DE2848423A1 (de) * 1978-11-08 1980-05-29 Merck Patent Gmbh Hydrocortisonester, diese enthaltende pharmazeutische zubereitungen und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
DD208812A5 (de) 1984-04-11
JPS57167999A (en) 1982-10-16
DK571981A (da) 1982-06-24
US4912098A (en) 1990-03-27
CS221883A2 (en) 1984-02-13
CS231197B2 (en) 1984-10-15
CS222081A2 (en) 1984-02-13
CS221981A2 (en) 1984-02-13
CS221781A2 (en) 1984-02-13
CS231198B2 (en) 1984-10-15
PL234367A1 (en) 1983-02-28
ES8302027A1 (es) 1983-02-01
GR76975B (xx) 1984-09-04
CA1185234A (en) 1985-04-09
YU103383A (en) 1983-12-31
FI814126L (fi) 1982-06-24
PH17637A (en) 1984-10-18
DK159324C (da) 1991-02-25
FI72729B (fi) 1987-03-31
PL238738A1 (en) 1983-05-09
YU102083A (en) 1983-10-31
BG38337A3 (en) 1985-11-15
ES508325A0 (es) 1983-08-01
CS231200B2 (en) 1984-10-15
NO814394L (no) 1982-06-24
EP0054786B1 (de) 1985-03-20
GB2089809B (en) 1984-09-26
PL238740A1 (en) 1983-05-09
RO83669A (ro) 1984-06-21
DE3169460D1 (en) 1985-04-25
GB2089809A (en) 1982-06-30
IL64614A0 (en) 1982-03-31
EP0054786A1 (de) 1982-06-30
CS8109720A2 (en) 1984-02-13
YU103283A (en) 1983-10-31
ES8307896A1 (es) 1983-08-01
PT74183B (de) 1983-05-18
NO156409C (no) 1987-09-30
ES8401988A1 (es) 1984-01-16
SU1245264A3 (ru) 1986-07-15
PL130895B1 (en) 1984-09-29
JPH0257559B2 (xx) 1990-12-05
SU1255053A3 (ru) 1986-08-30
PL238739A1 (en) 1983-05-09
PL238741A1 (en) 1983-05-09
PL130894B1 (en) 1984-09-29
RO83669B (ro) 1984-08-30
IL64614A (en) 1985-06-30
IE52511B1 (en) 1987-11-25
NO156409B (no) 1987-06-09
CS231188B2 (en) 1984-10-15
DK159324B (da) 1990-10-01
PT74183A (de) 1982-01-01
AU7854981A (en) 1982-07-01
BG38338A3 (en) 1985-11-15
ES521498A0 (es) 1984-01-16
ES510339A0 (es) 1983-02-01
FI72729C (fi) 1987-07-10
DD202580A5 (de) 1983-09-21
YU103183A (en) 1983-10-31
HU186460B (en) 1985-08-28
ATE12237T1 (de) 1985-04-15
ZA818907B (en) 1982-11-24
AU548999B2 (en) 1986-01-09
CS231199B2 (en) 1984-10-15

Similar Documents

Publication Publication Date Title
ZA826017B (en) Novel 6alpha-methylprednisolone derivatives and their manufacture and use
RO92853B1 (ro) Procedeu pentru prepararea unor derivati de 6,16-dimetilcorticoide
YU103383A (en) Process for obtaining new 6-alpha-methyl-hydrocortisone derivatives
JPS57203079A (en) Novel benzofuran derivative, manufacture and antiinflammatory medicine containing same
JPS57144299A (en) Novel manufacture of 17 alpha-hydroxy-17 beta- hydroxyacetylsteroid and corresponding intermediate therefrom
IE800640L (en) 11-methylene steroids