FI814126L - Nya 6alfa-metylhydrokortisonderivat deras framstaellning och anvaendning - Google Patents

Nya 6alfa-metylhydrokortisonderivat deras framstaellning och anvaendning

Info

Publication number
FI814126L
FI814126L FI814126A FI814126A FI814126L FI 814126 L FI814126 L FI 814126L FI 814126 A FI814126 A FI 814126A FI 814126 A FI814126 A FI 814126A FI 814126 L FI814126 L FI 814126L
Authority
FI
Finland
Prior art keywords
methylhydrocortisonderivat
6alfa
nya
deras framstaellning
framstaellning och
Prior art date
Application number
FI814126A
Other languages
English (en)
Other versions
FI72729B (fi
FI72729C (fi
Inventor
Klaus Annen
Karl Petzoldt
Henry Laurent
Rudolf Wiechert
Helmut Hofmeister
Hans Wendt
Manfred Albring
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of FI814126L publication Critical patent/FI814126L/fi
Publication of FI72729B publication Critical patent/FI72729B/fi
Application granted granted Critical
Publication of FI72729C publication Critical patent/FI72729C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00Preparation of steroids
    • C12P33/06Hydroxylating
    • C12P33/08Hydroxylating at 11 position
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Fats And Perfumes (AREA)
  • Anti-Oxidant Or Stabilizer Compositions (AREA)
  • Lubricants (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Cephalosporin Compounds (AREA)
FI814126A 1980-12-23 1981-12-22 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 6 -metylhydrokortisonderivat. FI72729C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3049400 1980-12-23
DE3049400 1980-12-23

Publications (3)

Publication Number Publication Date
FI814126L true FI814126L (fi) 1982-06-24
FI72729B FI72729B (fi) 1987-03-31
FI72729C FI72729C (fi) 1987-07-10

Family

ID=6120491

Family Applications (1)

Application Number Title Priority Date Filing Date
FI814126A FI72729C (fi) 1980-12-23 1981-12-22 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 6 -metylhydrokortisonderivat.

Country Status (26)

Country Link
US (1) US4912098A (fi)
EP (1) EP0054786B1 (fi)
JP (1) JPS57167999A (fi)
AT (1) ATE12237T1 (fi)
AU (1) AU548999B2 (fi)
BG (2) BG38337A3 (fi)
CA (1) CA1185234A (fi)
CS (5) CS221883A2 (fi)
DD (2) DD202580A5 (fi)
DE (1) DE3169460D1 (fi)
DK (1) DK159324C (fi)
ES (3) ES8307896A1 (fi)
FI (1) FI72729C (fi)
GB (1) GB2089809B (fi)
GR (1) GR76975B (fi)
HU (1) HU186460B (fi)
IE (1) IE52511B1 (fi)
IL (1) IL64614A (fi)
NO (1) NO156409C (fi)
PH (1) PH17637A (fi)
PL (5) PL238738A1 (fi)
PT (1) PT74183B (fi)
RO (1) RO83669B (fi)
SU (2) SU1245264A3 (fi)
YU (5) YU293181A (fi)
ZA (1) ZA818907B (fi)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3133081A1 (de) * 1981-08-18 1983-03-10 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue 6(alpha)-methylprednisolon-derivate, ihre herstellung und verwendung
DE3227312A1 (de) * 1982-07-19 1984-01-19 Schering AG, 1000 Berlin und 4709 Bergkamen Neue 6,16-dimethylkortikoide, ihre herstellung und verwendung
DE3243482A1 (de) * 1982-11-22 1984-05-24 Schering AG, 1000 Berlin und 4709 Bergkamen Neue 6(alpha)-methylkortikoide, ihre herstellung und verwendung
DE3427486A1 (de) * 1984-07-23 1986-01-30 Schering AG, Berlin und Bergkamen, 1000 Berlin Verfahren zur herstellung von 6(alpha)-methylsteroiden
CN102401624B (zh) * 2010-09-10 2014-07-16 珠海格力电器股份有限公司 步进电机行程位置检测装置及检测控制方法
CN102964414A (zh) * 2012-12-14 2013-03-13 中国科学院上海有机化学研究所 17位甾体羧酸酯的合成方法
EP3006453A1 (en) * 2014-10-08 2016-04-13 Cosmo Technologies Ltd. 17alpha-monoesters and 17alpha,21-diesters of cortexolone for use in the treatment of tumors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3141876A (en) * 1956-08-02 1964-07-21 Upjohn Co 3-keto-6-methyl-4-pregnene-3, 20-diones and a method for the production thereof
US3176032A (en) * 1958-04-18 1965-03-30 Syntex Corp 17alpha, 21-diacyloxy derivatives of 6alpha-methyl-delta1, 4-pregnadien-3, 20-dione and of 6alpha-methyl-delta4-pregnen-3, 20-dione
JPS6040439B2 (ja) * 1978-03-29 1985-09-11 大正製薬株式会社 ヒドロコルチゾン誘導体
DE2848423A1 (de) * 1978-11-08 1980-05-29 Merck Patent Gmbh Hydrocortisonester, diese enthaltende pharmazeutische zubereitungen und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
ZA818907B (en) 1982-11-24
SU1245264A3 (ru) 1986-07-15
ES508325A0 (es) 1983-08-01
YU102083A (en) 1983-10-31
ES8401988A1 (es) 1984-01-16
RO83669A (ro) 1984-06-21
DD208812A5 (de) 1984-04-11
CS231198B2 (en) 1984-10-15
DD202580A5 (de) 1983-09-21
GR76975B (fi) 1984-09-04
CS231200B2 (en) 1984-10-15
NO156409C (no) 1987-09-30
GB2089809B (en) 1984-09-26
PL234367A1 (en) 1983-02-28
ES8302027A1 (es) 1983-02-01
ES521498A0 (es) 1984-01-16
PL130894B1 (en) 1984-09-29
IL64614A (en) 1985-06-30
CS222081A2 (en) 1984-02-13
NO814394L (no) 1982-06-24
ATE12237T1 (de) 1985-04-15
EP0054786B1 (de) 1985-03-20
ES8307896A1 (es) 1983-08-01
PL130895B1 (en) 1984-09-29
YU103383A (en) 1983-12-31
JPH0257559B2 (fi) 1990-12-05
EP0054786A1 (de) 1982-06-30
CS221981A2 (en) 1984-02-13
US4912098A (en) 1990-03-27
BG38337A3 (en) 1985-11-15
FI72729B (fi) 1987-03-31
RO83669B (ro) 1984-08-30
ES510339A0 (es) 1983-02-01
YU293181A (en) 1983-10-31
DK571981A (da) 1982-06-24
CS221781A2 (en) 1984-02-13
CS231188B2 (en) 1984-10-15
DK159324C (da) 1991-02-25
PL238739A1 (en) 1983-05-09
AU7854981A (en) 1982-07-01
YU103183A (en) 1983-10-31
BG38338A3 (en) 1985-11-15
DK159324B (da) 1990-10-01
CS231197B2 (en) 1984-10-15
JPS57167999A (en) 1982-10-16
PT74183A (de) 1982-01-01
SU1255053A3 (ru) 1986-08-30
IE52511B1 (en) 1987-11-25
YU103283A (en) 1983-10-31
PH17637A (en) 1984-10-18
AU548999B2 (en) 1986-01-09
DE3169460D1 (en) 1985-04-25
CS8109720A2 (en) 1984-02-13
PL238738A1 (en) 1983-05-09
PT74183B (de) 1983-05-18
FI72729C (fi) 1987-07-10
CS231199B2 (en) 1984-10-15
PL238741A1 (en) 1983-05-09
IL64614A0 (en) 1982-03-31
GB2089809A (en) 1982-06-30
PL238740A1 (en) 1983-05-09
NO156409B (no) 1987-06-09
CA1185234A (en) 1985-04-09
CS221883A2 (en) 1984-02-13
HU186460B (en) 1985-08-28

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: SCHERING AKTIENGESELLSCHAFT