CS221781A2 - Zpusob vyroby derivatu 6alfa methylhydrokortisonu - Google Patents

Zpusob vyroby derivatu 6alfa methylhydrokortisonu

Info

Publication number
CS221781A2
CS221781A2 CS832217A CS221781A CS221781A2 CS 221781 A2 CS221781 A2 CS 221781A2 CS 832217 A CS832217 A CS 832217A CS 221781 A CS221781 A CS 221781A CS 221781 A2 CS221781 A2 CS 221781A2
Authority
CS
Czechoslovakia
Prior art keywords
methylhydrokortisonu
6alfa
zpusob vyroby
derivatu
vyroby derivatu
Prior art date
Application number
CS832217A
Other languages
English (en)
Inventor
Klaus Dr Annen
Karl Dr Petzold
Henry Dr Laurent
Rudolf Prof Wiechert
Helmut Dr Hofmeister
Hans Dr Wendt
Manfred Dr Albring
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of CS221781A2 publication Critical patent/CS221781A2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00—Preparation of steroids
    • C12P33/06—Hydroxylating
    • C12P33/08—Hydroxylating at 11 position
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Anti-Oxidant Or Stabilizer Compositions (AREA)
  • Lubricants (AREA)
  • Fats And Perfumes (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CS832217A 1980-12-23 1981-12-23 Zpusob vyroby derivatu 6alfa methylhydrokortisonu CS221781A2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3049400 1980-12-23

Publications (1)

Publication Number Publication Date
CS221781A2 true CS221781A2 (en) 1984-02-13

Family

ID=6120491

Family Applications (5)

Application Number Title Priority Date Filing Date
CS832220A CS222081A2 (en) 1980-12-23 1981-12-23 Zpusob vyroby derivatu 6alfa methylhydrokortisonu
CS819720A CS231200B2 (en) 1980-12-23 1981-12-23 Processing method of derivative of 6alpha-methylhydrokortisone
CS832217A CS221781A2 (en) 1980-12-23 1981-12-23 Zpusob vyroby derivatu 6alfa methylhydrokortisonu
CS832218A CS221883A2 (en) 1980-12-23 1981-12-23 Zpusob vyroby derivatu 6alfa methylhydrokortisonu
CS832219A CS221981A2 (en) 1980-12-23 1981-12-23 Zpusob vyroby derivatu 6alfa methylhydrokortisonu

Family Applications Before (2)

Application Number Title Priority Date Filing Date
CS832220A CS222081A2 (en) 1980-12-23 1981-12-23 Zpusob vyroby derivatu 6alfa methylhydrokortisonu
CS819720A CS231200B2 (en) 1980-12-23 1981-12-23 Processing method of derivative of 6alpha-methylhydrokortisone

Family Applications After (2)

Application Number Title Priority Date Filing Date
CS832218A CS221883A2 (en) 1980-12-23 1981-12-23 Zpusob vyroby derivatu 6alfa methylhydrokortisonu
CS832219A CS221981A2 (en) 1980-12-23 1981-12-23 Zpusob vyroby derivatu 6alfa methylhydrokortisonu

Country Status (26)

Country Link
US (1) US4912098A (cs)
EP (1) EP0054786B1 (cs)
JP (1) JPS57167999A (cs)
AT (1) ATE12237T1 (cs)
AU (1) AU548999B2 (cs)
BG (2) BG38338A3 (cs)
CA (1) CA1185234A (cs)
CS (5) CS222081A2 (cs)
DD (2) DD202580A5 (cs)
DE (1) DE3169460D1 (cs)
DK (1) DK159324C (cs)
ES (3) ES8307896A1 (cs)
FI (1) FI72729C (cs)
GB (1) GB2089809B (cs)
GR (1) GR76975B (cs)
HU (1) HU186460B (cs)
IE (1) IE52511B1 (cs)
IL (1) IL64614A (cs)
NO (1) NO156409C (cs)
PH (1) PH17637A (cs)
PL (5) PL130894B1 (cs)
PT (1) PT74183B (cs)
RO (1) RO83669B (cs)
SU (2) SU1255053A3 (cs)
YU (5) YU293181A (cs)
ZA (1) ZA818907B (cs)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3133081A1 (de) * 1981-08-18 1983-03-10 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue 6(alpha)-methylprednisolon-derivate, ihre herstellung und verwendung
DE3227312A1 (de) * 1982-07-19 1984-01-19 Schering AG, 1000 Berlin und 4709 Bergkamen Neue 6,16-dimethylkortikoide, ihre herstellung und verwendung
DE3243482A1 (de) * 1982-11-22 1984-05-24 Schering AG, 1000 Berlin und 4709 Bergkamen Neue 6(alpha)-methylkortikoide, ihre herstellung und verwendung
DE3427486A1 (de) * 1984-07-23 1986-01-30 Schering AG, Berlin und Bergkamen, 1000 Berlin Verfahren zur herstellung von 6(alpha)-methylsteroiden
CN102401624B (zh) * 2010-09-10 2014-07-16 珠海格力电器股份有限公司 步进电机行程位置检测装置及检测控制方法
CN102964414A (zh) * 2012-12-14 2013-03-13 中国科学院上海有机化学研究所 17位甾体羧酸酯的合成方法
EP3006453A1 (en) * 2014-10-08 2016-04-13 Cosmo Technologies Ltd. 17alpha-monoesters and 17alpha,21-diesters of cortexolone for use in the treatment of tumors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3141876A (en) * 1956-08-02 1964-07-21 Upjohn Co 3-keto-6-methyl-4-pregnene-3, 20-diones and a method for the production thereof
US3176032A (en) * 1958-04-18 1965-03-30 Syntex Corp 17alpha, 21-diacyloxy derivatives of 6alpha-methyl-delta1, 4-pregnadien-3, 20-dione and of 6alpha-methyl-delta4-pregnen-3, 20-dione
JPS6040439B2 (ja) * 1978-03-29 1985-09-11 大正製薬株式会社 ヒドロコルチゾン誘導体
DE2848423A1 (de) * 1978-11-08 1980-05-29 Merck Patent Gmbh Hydrocortisonester, diese enthaltende pharmazeutische zubereitungen und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
PT74183B (de) 1983-05-18
FI814126L (fi) 1982-06-24
PH17637A (en) 1984-10-18
CS8109720A2 (en) 1984-02-13
CA1185234A (en) 1985-04-09
NO156409B (no) 1987-06-09
AU548999B2 (en) 1986-01-09
DE3169460D1 (en) 1985-04-25
YU103183A (en) 1983-10-31
AU7854981A (en) 1982-07-01
SU1255053A3 (ru) 1986-08-30
ES521498A0 (es) 1984-01-16
IL64614A (en) 1985-06-30
ES510339A0 (es) 1983-02-01
PL238739A1 (en) 1983-05-09
DD202580A5 (de) 1983-09-21
GB2089809B (en) 1984-09-26
PL130895B1 (en) 1984-09-29
BG38338A3 (en) 1985-11-15
RO83669B (ro) 1984-08-30
FI72729B (fi) 1987-03-31
CS231197B2 (en) 1984-10-15
PL238740A1 (en) 1983-05-09
CS231198B2 (en) 1984-10-15
DK159324C (da) 1991-02-25
DD208812A5 (de) 1984-04-11
CS221981A2 (en) 1984-02-13
DK159324B (da) 1990-10-01
DK571981A (da) 1982-06-24
ES8302027A1 (es) 1983-02-01
GB2089809A (en) 1982-06-30
PL130894B1 (en) 1984-09-29
IE52511B1 (en) 1987-11-25
ATE12237T1 (de) 1985-04-15
CS231188B2 (en) 1984-10-15
CS231199B2 (en) 1984-10-15
HU186460B (en) 1985-08-28
JPH0257559B2 (cs) 1990-12-05
JPS57167999A (en) 1982-10-16
YU103383A (en) 1983-12-31
PT74183A (de) 1982-01-01
YU293181A (en) 1983-10-31
PL238738A1 (en) 1983-05-09
CS231200B2 (en) 1984-10-15
ES8401988A1 (es) 1984-01-16
ES508325A0 (es) 1983-08-01
PL238741A1 (en) 1983-05-09
US4912098A (en) 1990-03-27
NO156409C (no) 1987-09-30
CS221883A2 (en) 1984-02-13
SU1245264A3 (ru) 1986-07-15
NO814394L (no) 1982-06-24
CS222081A2 (en) 1984-02-13
FI72729C (fi) 1987-07-10
GR76975B (cs) 1984-09-04
RO83669A (ro) 1984-06-21
ES8307896A1 (es) 1983-08-01
YU103283A (en) 1983-10-31
BG38337A3 (en) 1985-11-15
EP0054786A1 (de) 1982-06-30
IL64614A0 (en) 1982-03-31
PL234367A1 (en) 1983-02-28
EP0054786B1 (de) 1985-03-20
YU102083A (en) 1983-10-31
ZA818907B (en) 1982-11-24

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