YU237283A - Process for obtaiing 7-carboxy-methoxy-phenyl-acetamido-3-cephem derivatives - Google Patents

Process for obtaiing 7-carboxy-methoxy-phenyl-acetamido-3-cephem derivatives

Info

Publication number
YU237283A
YU237283A YU02372/83A YU237283A YU237283A YU 237283 A YU237283 A YU 237283A YU 02372/83 A YU02372/83 A YU 02372/83A YU 237283 A YU237283 A YU 237283A YU 237283 A YU237283 A YU 237283A
Authority
YU
Yugoslavia
Prior art keywords
obtaiing
acetamido
carboxy
methoxy
phenyl
Prior art date
Application number
YU02372/83A
Other languages
English (en)
Inventor
Y Mashida
N Shigeto
N Seiichiro
K Takashi
K Kyosuke
S Isao
Original Assignee
Eisai C
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP21772682A external-priority patent/JPS59108791A/ja
Priority claimed from JP3601783A external-priority patent/JPS59161389A/ja
Application filed by Eisai C filed Critical Eisai C
Publication of YU237283A publication Critical patent/YU237283A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
YU02372/83A 1982-12-14 1983-12-05 Process for obtaiing 7-carboxy-methoxy-phenyl-acetamido-3-cephem derivatives YU237283A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP21772682A JPS59108791A (ja) 1982-12-14 1982-12-14 ７−カルボキシメトキシフエニルアセトアミド−３−セフエム誘導体、その製造方法およびそれからなる抗菌剤
JP3601783A JPS59161389A (ja) 1983-03-07 1983-03-07 ７−カルボキシメトキシフエニルアセトアミドセフエム誘導体，その製造法およびそれからなる抗菌剤

Publications (1)

Publication Number Publication Date
YU237283A true YU237283A (en) 1986-04-30

Family

ID=26375029

Family Applications (1)

Application Number Title Priority Date Filing Date
YU02372/83A YU237283A (en) 1982-12-14 1983-12-05 Process for obtaiing 7-carboxy-methoxy-phenyl-acetamido-3-cephem derivatives

Country Status (16)

Country Link
US (1) US4546176A (it)
KR (1) KR840007012A (it)
AT (1) ATA435283A (it)
AU (1) AU2082783A (it)
BE (1) BE898442A (it)
CH (1) CH656131A5 (it)
DE (1) DE3345093A1 (it)
DK (1) DK572183A (it)
ES (2) ES8506025A1 (it)
FR (1) FR2569195B1 (it)
GB (1) GB2132613B (it)
IT (1) IT1169969B (it)
NL (1) NL8304272A (it)
PH (1) PH20168A (it)
SE (1) SE8306882L (it)
YU (1) YU237283A (it)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5232918A (en) * 1987-07-23 1993-08-03 Imperial Chemical Industries Plc Cephalosporin derivatives
US5180719A (en) * 1988-10-24 1993-01-19 Norwich Eaton Pharmaceuticals, Inc. Antimicrobial quinolonyl lactam esters
US5328908A (en) * 1988-10-24 1994-07-12 Procter & Gamble Pharmaceuticals, Inc. Antimicrobial quinolone thioureas
US5273973A (en) * 1988-10-24 1993-12-28 Norwich Eaton Pharmaceuticals, Inc. Antimicrobial quinolonyl esters
CA2001203C (en) * 1988-10-24 2001-02-13 Thomas P. Demuth, Jr. Novel antimicrobial dithiocarbamoyl quinolones
EP0997466A1 (en) * 1988-10-24 2000-05-03 PROCTER & GAMBLE PHARMACEUTICALS, INC. Novel antimicrobial lactam-quinolones
US5491139A (en) * 1988-10-24 1996-02-13 The Procter & Gamble Company Antimicrobial quinolonyl lactams
JPH05506033A (ja) * 1990-04-18 1993-09-02 ノーウィッチ、イートン、ファーマスーティカルズ、インコーポレーテッド 抗微生物性キノロニルラクタム類
US5244892A (en) * 1990-10-16 1993-09-14 Kyorin Pharmaceutical Co., Ltd. Cephem compounds, and antibacterial agents
EP0775145A1 (en) * 1994-08-02 1997-05-28 The Procter & Gamble Company Process for making quinolonyl lactam antimicrobials and novel intermediate compounds
ATE190972T1 (de) * 1994-08-02 2000-04-15 Procter & Gamble Verfahren zur herstellung von antimikrobiellen verbindungen
TW200420573A (en) * 2002-09-26 2004-10-16 Rib X Pharmaceuticals Inc Bifunctional heterocyclic compounds and methods of making and using same
JP2006523229A (ja) * 2003-03-05 2006-10-12 リブ−エックス ファーマシューティカルズ，インコーポレイテッド 二官能性複素環式化合物ならびにその製造および使用方法
EP1682563A1 (en) * 2003-10-30 2006-07-26 Rib-X Pharmaceuticals, Inc. Bifunctional macrolide heterocyclic compounds and mehtods of making and using the same
JP2007512256A (ja) * 2003-11-18 2007-05-17 リブ−エックス ファーマシューティカルズ，インコーポレイテッド 二官能性マクロライド複素環化合物ならびにこれらを製造する方法およびこれらを使用する方法
JP5383037B2 (ja) * 2004-02-27 2014-01-08 リブ−エックス ファーマシューティカルズ，インコーポレイテッド 大環状化合物およびそれらを製造し使用する方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR208171A1 (es) * 1972-09-29 1976-12-09 Ciba Geigy Ag Procedimiento para la obtencion de nuevos derivados del acido cef-3-em-4-carboxilico
US4338439A (en) * 1976-08-26 1982-07-06 Eli Lilly And Company 7-[2-[(Substituted benzoyl]amino]acetamido]cephalosporins
SE8009049L (sv) * 1980-03-04 1981-09-05 Eisai Co Ltd 7alfa-metoxicefalosporinderivat, sett for framstellning derav och antibakteriella lekemedel innehallande dessa foreningar
US4468394A (en) * 1981-04-02 1984-08-28 Eisai Co., Ltd. Cephalosporin compounds

Also Published As

Publication number Publication date
ES8505691A1 (es) 1985-06-01
BE898442A (fr) 1984-06-13
GB2132613B (en) 1986-05-08
FR2569195B1 (fr) 1987-01-09
US4546176A (en) 1985-10-08
NL8304272A (nl) 1984-07-02
KR840007012A (ko) 1984-12-04
AU2082783A (en) 1984-06-21
DK572183A (da) 1984-06-27
ES528003A0 (es) 1985-06-16
DK572183D0 (da) 1983-12-13
ES534297A0 (es) 1985-06-01
ATA435283A (de) 1986-12-15
PH20168A (en) 1986-10-09
GB8329554D0 (en) 1983-12-07
DE3345093A1 (de) 1984-06-14
FR2569195A1 (fr) 1986-02-21
ES8506025A1 (es) 1985-06-16
GB2132613A (en) 1984-07-11
CH656131A5 (de) 1986-06-13
IT8324122A0 (it) 1983-12-12
SE8306882D0 (sv) 1983-12-13
SE8306882L (sv) 1984-06-15
IT1169969B (it) 1987-06-03

Similar Documents

Publication Publication Date Title
RO86234B (ro) Procedeu pentru prepararea unor derivati de aciloxipurine substituite
HUT34984A (en) Process for peneme derivatives
PL243555A1 (en) Process for preparing n-formyl- and n-hydroxymethyl-3-phenoxy-1-azetidinecarboxamides
YU237283A (en) Process for obtaiing 7-carboxy-methoxy-phenyl-acetamido-3-cephem derivatives
YU43822B (en) Process for obtaining new cephalosporinic derivatives
HU188278B (en) Process for preparing 4-aryl-4-piperidinyl-carbonols
DE3380061D1 (en) Process for preparing dinitrobenzophenones
PL243255A1 (en) Process for preparing 3-phenoxy-1-azetidinecarboxamides
YU43196B (en) Process for obtaining carbapenem derivatives
YU246583A (en) Process for making 14-acyloxi-2-halo-antracycline derivatives
YU44758B (en) Process for obtaining new phenothiazino derivatives
RO87690B (ro) Procedeu pentru prepararea unor derivati de tetrazol
DE3380846D1 (en) Process for preparing 2-alkylamino- and 2-amino-5-alkylpyridines
YU42856B (en) Process for obtaining new cycloalcanic derivatives
IL70220A0 (en) Process for 1-oxa-beta-lactams
YU45150B (en) Process for obtaining substituted 1-pyridiloxi-3-indolylalkylamino-2-propanole
GB2115809B (en) Process for preparing 4-amino-5-dialkoxy-methylpyrimidine derivatives
YU169783A (en) Process for obtaining new 28-methyl-brassionosteroid derivatives
PT76447B (en) Process for preparing n-substituted-tetrahydrothiazines
DE3366914D1 (en) Process for preparing 2-hydroxy-2-phenylethylamines
IL68402A (en) Process for making thiobiscarbamates
HUT40420A (en) Process for preparing n-phenyl-pyridine-amino-derivatives
YU43419B (en) Process for obtaining new izoquinolinic derivatives
CS455083A2 (en) Process for preparing 1-aryl-2-amino-1-ethanoles
IL70420A (en) Process for preparing 3-bromo-3-methylcepham derivatives