IT1169969B - Derivati del 7-carbossimetossifenilacetammido-3-cefeme, procedimenti per la loro preparazione e preparazioni antibatteriche che li contengono - Google Patents
Derivati del 7-carbossimetossifenilacetammido-3-cefeme, procedimenti per la loro preparazione e preparazioni antibatteriche che li contengonoInfo
- Publication number
- IT1169969B IT1169969B IT24122/83A IT2412283A IT1169969B IT 1169969 B IT1169969 B IT 1169969B IT 24122/83 A IT24122/83 A IT 24122/83A IT 2412283 A IT2412283 A IT 2412283A IT 1169969 B IT1169969 B IT 1169969B
- Authority
- IT
- Italy
- Prior art keywords
- cefeme
- carboxymetoxyphenylacetamido
- procedures
- derivatives
- contain
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title 2
- 230000000844 anti-bacterial effect Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
- C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/36—Methylene radicals, substituted by sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
- C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP21772682A JPS59108791A (ja) | 1982-12-14 | 1982-12-14 | ７−カルボキシメトキシフエニルアセトアミド−３−セフエム誘導体、その製造方法およびそれからなる抗菌剤 |
| JP3601783A JPS59161389A (ja) | 1983-03-07 | 1983-03-07 | ７−カルボキシメトキシフエニルアセトアミドセフエム誘導体，その製造法およびそれからなる抗菌剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8324122A0 IT8324122A0 (it) | 1983-12-12 |
| IT1169969B true IT1169969B (it) | 1987-06-03 |
Family
ID=26375029
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT24122/83A IT1169969B (it) | 1982-12-14 | 1983-12-12 | Derivati del 7-carbossimetossifenilacetammido-3-cefeme, procedimenti per la loro preparazione e preparazioni antibatteriche che li contengono |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4546176A (it) |
| KR (1) | KR840007012A (it) |
| AT (1) | ATA435283A (it) |
| AU (1) | AU2082783A (it) |
| BE (1) | BE898442A (it) |
| CH (1) | CH656131A5 (it) |
| DE (1) | DE3345093A1 (it) |
| DK (1) | DK572183A (it) |
| ES (2) | ES528003A0 (it) |
| FR (1) | FR2569195B1 (it) |
| GB (1) | GB2132613B (it) |
| IT (1) | IT1169969B (it) |
| NL (1) | NL8304272A (it) |
| PH (1) | PH20168A (it) |
| SE (1) | SE8306882L (it) |
| YU (1) | YU237283A (it) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5232918A (en) * | 1987-07-23 | 1993-08-03 | Imperial Chemical Industries Plc | Cephalosporin derivatives |
| US5491139A (en) * | 1988-10-24 | 1996-02-13 | The Procter & Gamble Company | Antimicrobial quinolonyl lactams |
| EP0997466A1 (en) * | 1988-10-24 | 2000-05-03 | PROCTER & GAMBLE PHARMACEUTICALS, INC. | Novel antimicrobial lactam-quinolones |
| CA2001203C (en) * | 1988-10-24 | 2001-02-13 | Thomas P. Demuth, Jr. | Novel antimicrobial dithiocarbamoyl quinolones |
| US5328908A (en) * | 1988-10-24 | 1994-07-12 | Procter & Gamble Pharmaceuticals, Inc. | Antimicrobial quinolone thioureas |
| US5180719A (en) * | 1988-10-24 | 1993-01-19 | Norwich Eaton Pharmaceuticals, Inc. | Antimicrobial quinolonyl lactam esters |
| US5273973A (en) * | 1988-10-24 | 1993-12-28 | Norwich Eaton Pharmaceuticals, Inc. | Antimicrobial quinolonyl esters |
| KR100204987B1 (ko) * | 1990-04-18 | 1999-06-15 | 제이코버스 코넬리스 레이서 | 항미생물성 퀴놀로닐 락탐 |
| US5244892A (en) * | 1990-10-16 | 1993-09-14 | Kyorin Pharmaceutical Co., Ltd. | Cephem compounds, and antibacterial agents |
| ATE190972T1 (de) * | 1994-08-02 | 2000-04-15 | Procter & Gamble | Verfahren zur herstellung von antimikrobiellen verbindungen |
| CN1159809A (zh) * | 1994-08-02 | 1997-09-17 | 普罗克特和甘保尔公司 | 喹诺酮基内酰胺抗微生物化合物和新型的中间体化合物的制备方法 |
| AR043050A1 (es) * | 2002-09-26 | 2005-07-13 | Rib X Pharmaceuticals Inc | Compuestos heterociclicos bifuncionales y metodos para preparar y usar los mismos |
| AU2004217919A1 (en) * | 2003-03-05 | 2004-09-16 | Rib-X Pharmaceuticals, Inc. | Bifunctional heterocyclic compounds and methods of making and using the same |
| EP1682563A1 (en) * | 2003-10-30 | 2006-07-26 | Rib-X Pharmaceuticals, Inc. | Bifunctional macrolide heterocyclic compounds and mehtods of making and using the same |
| JP2007512256A (ja) * | 2003-11-18 | 2007-05-17 | リブ−エックス ファーマシューティカルズ，インコーポレイテッド | 二官能性マクロライド複素環化合物ならびにこれらを製造する方法およびこれらを使用する方法 |
| EP1723159B1 (en) | 2004-02-27 | 2019-06-12 | Melinta Therapeutics, Inc. | Macrocyclic compounds and methods of making and using the same |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR208171A1 (es) * | 1972-09-29 | 1976-12-09 | Ciba Geigy Ag | Procedimiento para la obtencion de nuevos derivados del acido cef-3-em-4-carboxilico |
| US4338439A (en) * | 1976-08-26 | 1982-07-06 | Eli Lilly And Company | 7-[2-[(Substituted benzoyl]amino]acetamido]cephalosporins |
| SE8009049L (sv) * | 1980-03-04 | 1981-09-05 | Eisai Co Ltd | 7alfa-metoxicefalosporinderivat, sett for framstellning derav och antibakteriella lekemedel innehallande dessa foreningar |
| US4468394A (en) * | 1981-04-02 | 1984-08-28 | Eisai Co., Ltd. | Cephalosporin compounds |
-
1983
- 1983-10-20 US US06/544,406 patent/US4546176A/en not_active Expired - Fee Related
- 1983-10-31 AU AU20827/83A patent/AU2082783A/en not_active Abandoned
- 1983-11-04 GB GB08329554A patent/GB2132613B/en not_active Expired
- 1983-11-23 PH PH29873A patent/PH20168A/en unknown
- 1983-12-05 YU YU02372/83A patent/YU237283A/xx unknown
- 1983-12-12 IT IT24122/83A patent/IT1169969B/it active
- 1983-12-12 NL NL8304272A patent/NL8304272A/nl not_active Application Discontinuation
- 1983-12-12 FR FR8319876A patent/FR2569195B1/fr not_active Expired
- 1983-12-13 SE SE8306882A patent/SE8306882L/xx not_active Application Discontinuation
- 1983-12-13 BE BE0/212036A patent/BE898442A/fr not_active IP Right Cessation
- 1983-12-13 ES ES528003A patent/ES528003A0/es active Granted
- 1983-12-13 DK DK572183A patent/DK572183A/da not_active Application Discontinuation
- 1983-12-13 CH CH6649/83A patent/CH656131A5/de not_active IP Right Cessation
- 1983-12-13 DE DE19833345093 patent/DE3345093A1/de not_active Withdrawn
- 1983-12-14 KR KR1019830005939A patent/KR840007012A/ko not_active Withdrawn
- 1983-12-14 AT AT0435283A patent/ATA435283A/de not_active Application Discontinuation
-
1984
- 1984-07-13 ES ES534297A patent/ES8505691A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| SE8306882L (sv) | 1984-06-15 |
| GB8329554D0 (en) | 1983-12-07 |
| PH20168A (en) | 1986-10-09 |
| DK572183A (da) | 1984-06-27 |
| IT8324122A0 (it) | 1983-12-12 |
| CH656131A5 (de) | 1986-06-13 |
| NL8304272A (nl) | 1984-07-02 |
| ES8506025A1 (es) | 1985-06-16 |
| ES528003A0 (es) | 1985-06-16 |
| YU237283A (en) | 1986-04-30 |
| GB2132613A (en) | 1984-07-11 |
| AU2082783A (en) | 1984-06-21 |
| FR2569195B1 (fr) | 1987-01-09 |
| SE8306882D0 (sv) | 1983-12-13 |
| BE898442A (fr) | 1984-06-13 |
| FR2569195A1 (fr) | 1986-02-21 |
| DK572183D0 (da) | 1983-12-13 |
| ES534297A0 (es) | 1985-06-01 |
| GB2132613B (en) | 1986-05-08 |
| ES8505691A1 (es) | 1985-06-01 |
| DE3345093A1 (de) | 1984-06-14 |
| KR840007012A (ko) | 1984-12-04 |
| US4546176A (en) | 1985-10-08 |
| ATA435283A (de) | 1986-12-15 |
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