YU20702A - Konjugati boja-antitelo prema ciljnim strukturama angiogeneze za intraoperativno predstavljanje oboda tumora - Google Patents

Konjugati boja-antitelo prema ciljnim strukturama angiogeneze za intraoperativno predstavljanje oboda tumora

Info

Publication number
YU20702A
YU20702A YU20702A YUP20702A YU20702A YU 20702 A YU20702 A YU 20702A YU 20702 A YU20702 A YU 20702A YU P20702 A YUP20702 A YU P20702A YU 20702 A YU20702 A YU 20702A
Authority
YU
Yugoslavia
Prior art keywords
near infrared
contrast agent
fluorescence imaging
infrared fluorescent
fluorescent contrast
Prior art date
Application number
YU20702A
Other languages
English (en)
Inventor
Michael Schirner
Kai Licha
Ludger Dinkelborg
Original Assignee
Schering Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7924318&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=YU20702(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Aktiengesellschaft filed Critical Schering Aktiengesellschaft
Publication of YU20702A publication Critical patent/YU20702A/sh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0058—Antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032—Methine dyes, e.g. cyanine dyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0039—Coumarin dyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0041—Xanthene dyes, used in vivo, e.g. administered to a mice, e.g. rhodamines, rose Bengal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0041—Xanthene dyes, used in vivo, e.g. administered to a mice, e.g. rhodamines, rose Bengal
    • A61K49/0043—Fluorescein, used in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Opisuju se konjugati boja-antitela, koji su sposobni da se vezuju na strukture novostvorenih sudova i njihova primena za intraoperativno predstavljanje patološke angiogeneze.[The invention relates to antibody dye conjugates which are suited for binding to structures of newly formed vessels and to the their use for interoperatively depicting pathological angiogenesis.
YU20702A 1999-09-24 2000-08-19 Konjugati boja-antitelo prema ciljnim strukturama angiogeneze za intraoperativno predstavljanje oboda tumora YU20702A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19947559A DE19947559A1 (de) 1999-09-24 1999-09-24 Antikörper-Farbstoffkonjugate gegen Zielstrukturen der Angiogenese zur intraoperativen Tumorranddarstellung

Publications (1)

Publication Number Publication Date
YU20702A true YU20702A (sh) 2005-06-10

Family

ID=7924318

Family Applications (1)

Application Number Title Priority Date Filing Date
YU20702A YU20702A (sh) 1999-09-24 2000-08-19 Konjugati boja-antitelo prema ciljnim strukturama angiogeneze za intraoperativno predstavljanje oboda tumora

Country Status (23)

Country Link
EP (2) EP1214099A1 (sh)
JP (1) JP2003510294A (sh)
KR (2) KR100832937B1 (sh)
CN (1) CN1269530C (sh)
AU (1) AU779026B2 (sh)
BG (1) BG65682B1 (sh)
BR (1) BR0014192A (sh)
CA (1) CA2385593A1 (sh)
CZ (1) CZ2002991A3 (sh)
DE (1) DE19947559A1 (sh)
EE (1) EE05176B1 (sh)
HK (1) HK1050491A1 (sh)
HU (1) HUP0202625A2 (sh)
IL (2) IL148405A0 (sh)
MX (1) MXPA02002639A (sh)
NO (1) NO20021441L (sh)
NZ (1) NZ517944A (sh)
RO (1) RO121598B1 (sh)
RU (1) RU2002109237A (sh)
SK (1) SK3972002A3 (sh)
WO (1) WO2001023005A1 (sh)
YU (1) YU20702A (sh)
ZA (1) ZA200203225B (sh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003524018A (ja) 2000-02-24 2003-08-12 アイトゲネーシシェ テクニシェ ホッホシューレ チューリッヒ フィブロネクチンのｅｄ‐ｂドメインに特異的な抗体、前記抗体を含む複合体、および血管形成を検出および治療するためのその使用
US6440389B1 (en) * 2000-07-19 2002-08-27 The General Hospital Corporation Fluorescent agents for real-time measurement of organ function
AT413487B (de) * 2002-08-12 2006-03-15 Igeneon Krebs Immuntherapie Verwendung von antikörpern gegen ein tumor-assoziiertes antigen
NO20034351D0 (no) * 2003-09-29 2003-09-29 Amersham Health As Optisk avbilding av endometrose
ATE374367T1 (de) * 2004-07-22 2007-10-15 Bayer Schering Pharma Ag Verwendung von cyanin-farbstoffen zur diagnose von krankheiten, welche mit angiogenese assoziert sind
EP1679082A1 (en) * 2005-01-07 2006-07-12 Schering AG Use of cyanine dyes for the diagnosis of proliferative diseases
US20120041305A1 (en) * 2009-04-21 2012-02-16 The University Of Utah Research Foundation Light-emitting dye for intraoperative imaging or sentinel lymph node biopsy
WO2018026965A1 (en) * 2016-08-02 2018-02-08 Isi Life Sciences, Inc. Compositions and methods for detecting cancer cells in a tissue sample

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4341223A (en) * 1981-02-04 1982-07-27 Lutz Lauralee A Fluoresceable composition and method of determining fluid flow
WO1996001653A1 (en) * 1994-07-11 1996-01-25 Board Of Regents, The University Of Texas System Methods and compositions for the specific coagulation of vasculature
TWI259837B (en) * 1998-05-11 2006-08-11 Eidgenossische Tech Hochscule Specific binding molecules for scintigraphy, conjugates containing them and therapeutic method for treatment of angiogenesis

Also Published As

Publication number Publication date
KR20070087232A (ko) 2007-08-27
HK1050491A1 (en) 2003-06-27
NO20021441D0 (no) 2002-03-22
WO2001023005A1 (de) 2001-04-05
DE19947559A1 (de) 2001-04-19
CN1269530C (zh) 2006-08-16
CA2385593A1 (en) 2001-04-05
NO20021441L (no) 2002-05-15
PL354027A1 (en) 2003-12-15
EE05176B1 (et) 2009-06-15
HUP0202625A2 (en) 2002-12-28
EE200200152A (et) 2003-04-15
RU2002109237A (ru) 2003-11-27
KR100832937B1 (ko) 2008-05-27
EP1532988A3 (de) 2008-09-17
EP1532988A2 (de) 2005-05-25
BG106528A (bg) 2002-12-29
BR0014192A (pt) 2002-05-21
BG65682B1 (bg) 2009-06-30
IL148405A (en) 2009-06-15
IL148405A0 (en) 2002-09-12
CN1376074A (zh) 2002-10-23
MXPA02002639A (es) 2002-07-30
ZA200203225B (en) 2003-07-23
CZ2002991A3 (cs) 2002-06-12
AU779026B2 (en) 2005-01-06
JP2003510294A (ja) 2003-03-18
RO121598B1 (ro) 2007-12-28
SK3972002A3 (en) 2002-09-10
AU6702600A (en) 2001-04-30
NZ517944A (en) 2004-06-25
KR20020039349A (ko) 2002-05-25
EP1214099A1 (de) 2002-06-19

Similar Documents

Publication Publication Date Title
AU3491001A (en) Compositions and methods for the early diagnosis of ovarian cancer
AU3983201A (en) Compositions and methods for the early diagnosis of ovarian cancer
MXPA03003151A (es) Metodos de diagnostico de cancer de prostata, composiciones y metodos para seleccionar moduladores de cancer de prostata.
AU6299401A (en) Improvements to the fluorescent polymer-qtl approach to biosensing
ATE403439T1 (de) Lyophilisierte zubereitung enthaltend antikörper gegen den egf-rezeptor
AU2001231199A1 (en) Compositions and methods for the early diagnosis of ovarian cancer
HUP0103503A3 (en) Near infrared fluorescent contrast agent and fluorescence imaging using said contrast agent
WO2004058171A3 (en) Antibodies against gpr64 and uses thereof
PL354508A1 (en) Antibody to human gastrointestinal epithelial tumor antigen related to alpha 6 beta 4 integrin
NO970986D0 (no) API-bestemmelse ved bruk av fluorescensmålinger
WO2001082976A3 (en) Functional mri agents for cancer imaging
PL355891A1 (en) Near infrared fluorescent contrast agent and fluorescence imaging
NO20011943D0 (no) Forhjulsoppheng for busser o.l.
YU20702A (sh) Konjugati boja-antitelo prema ciljnim strukturama angiogeneze za intraoperativno predstavljanje oboda tumora
WO2002031209A3 (en) Genes related to development of refractory prostate cancer
MXPA03002323A (es) Metodos de diagnostico de cancer colorectal, composiciones y metodos para seleccionar moduladores de cancer colorectal.
AU2002246519A8 (en) Compositions and methods for the therapy and diagnosis of colon cancer
DE50003369D1 (de) Neue carbopyronin-fluoreszenz-farbstoffe
ZA200107906B (en) Anti-idiotypic antibodies against antibodies which inhibit the binding of immunoglobuline to its high affinity receptor.
DZ2665A1 (fr) Conjugués utiles pour le traitement du cancer de la prostate.
DE50006526D1 (de) Verwendung von anti-idiotypischen antikörpern als impfstoffe gegen krebs
EP1349485A4 (en) COMPOSITIONS AND METHODS FOR THE THERAPY AND DIAGNOSIS OF OVARIAL CARCINOMA
GB0011439D0 (en) Cancer diagnosis and assays for screening
AU3483001A (en) Compositions and methods for the therapy and diagnosis of ovarian cancer
IL151325A0 (en) Novel antibody with specificity for colon cancer