WO2002031209A3 - Genes related to development of refractory prostate cancer - Google Patents

Genes related to development of refractory prostate cancer Download PDF

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Publication number
WO2002031209A3
WO2002031209A3 PCT/US2001/031932 US0131932W WO0231209A3 WO 2002031209 A3 WO2002031209 A3 WO 2002031209A3 US 0131932 W US0131932 W US 0131932W WO 0231209 A3 WO0231209 A3 WO 0231209A3
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WO
WIPO (PCT)
Prior art keywords
refractory prostate
prostate cancer
development
hormone
genes related
Prior art date
Application number
PCT/US2001/031932
Other languages
French (fr)
Other versions
WO2002031209A2 (en
Inventor
Spyro Mousses
Olli P Kallioniemi
Lukas Bubendorf
Original Assignee
Us Gov Health & Human Serv
Spyro Mousses
Olli P Kallioniemi
Lukas Bubendorf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Gov Health & Human Serv, Spyro Mousses, Olli P Kallioniemi, Lukas Bubendorf filed Critical Us Gov Health & Human Serv
Priority to AU2002214576A priority Critical patent/AU2002214576A1/en
Publication of WO2002031209A2 publication Critical patent/WO2002031209A2/en
Publication of WO2002031209A3 publication Critical patent/WO2002031209A3/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

The present disclosure provides hormone-refractory prostate cancer (HPRC)-related nucleic acid molecules and proteins useful for the detection of neoplasms, particularly prostate and more specifically hormone-refractory prostate cancers. Also provided are methods of using these biological materials in the diagnosis, staging, detection, and treatment of neoplasia, and particularly hormone-refractory prostate cancer.
PCT/US2001/031932 2000-10-13 2001-10-12 Genes related to development of refractory prostate cancer WO2002031209A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002214576A AU2002214576A1 (en) 2000-10-13 2001-10-12 Genes related to development of refractory prostate cancer

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24058500P 2000-10-13 2000-10-13
US60/240,585 2000-10-13

Publications (2)

Publication Number Publication Date
WO2002031209A2 WO2002031209A2 (en) 2002-04-18
WO2002031209A3 true WO2002031209A3 (en) 2003-08-28

Family

ID=22907131

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/031932 WO2002031209A2 (en) 2000-10-13 2001-10-12 Genes related to development of refractory prostate cancer

Country Status (2)

Country Link
AU (1) AU2002214576A1 (en)
WO (1) WO2002031209A2 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020142327A1 (en) * 2000-11-28 2002-10-03 Gillis Kimberly A. Expression analysis of smarc nucleic acids and polypeptides useful in the diagnosis and treatment of prostate cancer
NZ526708A (en) 2000-11-28 2005-07-29 Wyeth Corp Expression analysis of FKBP nucleic acids and polypeptides useful in the diagnosis and treatment of prostate cancer
US20030235816A1 (en) * 2002-03-14 2003-12-25 Baylor College Of Medicine (By Slawin And Shariat) Method to determine outcome for patients with prostatic disease
TW200413539A (en) * 2002-09-30 2004-08-01 Oncotherapy Science Inc Genes and polypeptides relating to prostate cancers
ITBZ20020040A1 (en) * 2002-10-11 2004-04-12 Saverio Bettuzzi METHOD FOR IDENTIFICATION THROUGH THE DESIGN AND USE OF APPROPRIATE MICROCHIP -DNA MICROARRAY OF THE TUMOR TRANSFORMATION OF THE PROSTATIC TISSUE, ASSESSMENT OF ITS MALIGNITY AND PROGNOSIS OF HUMAN PROSTATIC CANCER BY A NEW ME
GB0227908D0 (en) 2002-11-29 2003-01-08 Univ London Cancer related methods and means
WO2005083118A2 (en) * 2004-02-27 2005-09-09 Oncotherapy Science, Inc. Pin-prc transition genes
EP1737980A2 (en) 2004-04-09 2007-01-03 Fondazione IRCCS Istituto Nazionale dei Tumori Gene expression markers for predicting response to chemotherapy
EP2311984A1 (en) * 2004-12-02 2011-04-20 Epigenomics AG Methods and nucleic acids for the analysis of gene expression associated with the prognosis of prostate cell proliferative disorders
EP2405022A3 (en) * 2008-07-08 2012-05-02 Genomic Health, Inc. Gene expression profiling for predicting the survivability of prostate cancer subjects
WO2010093872A2 (en) 2009-02-13 2010-08-19 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Molecular-based method of cancer diagnosis and prognosis
EP2913405B1 (en) 2010-07-27 2016-11-09 Genomic Health, Inc. Method for using gene expression to determine prognosis of prostate cancer
JP2012178990A (en) * 2011-02-28 2012-09-20 Soka Univ Method for detecting recurrent prostate cancer
CN102234632B (en) * 2011-04-29 2014-05-14 南方医科大学 Hybrid tumor DY01 of monoclonal antibody of human ubiquitin-conjugating enzyme UbcH10, and monoclonal antibody
CN102234631B (en) * 2011-04-29 2014-05-07 南方医科大学 Human ubiquitin-conjugating enzyme UbcH10 monoclonal antibody hybrid tumor DY03 and monoclonal antibody
CN102234633B (en) * 2011-04-29 2014-05-07 南方医科大学 Human ubiquitin-conjugating enzyme UbcH10 monoclonal antibody hybrid tumor DY02 and monoclonal antibody
JP6351112B2 (en) 2012-01-31 2018-07-04 ジェノミック ヘルス， インコーポレイテッド Gene expression profile algorithms and tests to quantify the prognosis of prostate cancer
US20150329912A1 (en) * 2013-01-13 2015-11-19 Emory University Biomarkers in cancer, methods, and systems related thereto
GB201322034D0 (en) 2013-12-12 2014-01-29 Almac Diagnostics Ltd Prostate cancer classification
WO2018022917A1 (en) * 2016-07-27 2018-02-01 Protagonist Therapeutics, Inc. Disulfide-rich peptide libraries and methods of use thereof

Citations (2)

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Publication number Priority date Publication date Assignee Title
WO1998056910A1 (en) * 1997-06-11 1998-12-17 Chiron Corporation DETECTION OF LOSS OF THE WILD-TYPE huBUB1 GENE
WO1999066051A2 (en) * 1998-06-16 1999-12-23 Sugen, Inc. Nek-related and bub1-related protein kinases

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998056910A1 (en) * 1997-06-11 1998-12-17 Chiron Corporation DETECTION OF LOSS OF THE WILD-TYPE huBUB1 GENE
WO1999066051A2 (en) * 1998-06-16 1999-12-23 Sugen, Inc. Nek-related and bub1-related protein kinases

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
BUBENDORF L ET AL: "HORMONE THERAPY FAILURE IN HUMAN PROSTATE CANCER: ANALYSIS BY COMPLEMENTARY DNA AND TISSUE MICROARRAYS", JOURNAL OF THE NATIONAL CANCER INSTITUTE, US DEPT. OF HEALTH, EDICATIONAND WELFARE, PUBLIC HEALTH, US, vol. 91, no. 20, 20 October 1999 (1999-10-20), pages 1758 - 1764, XP002934471, ISSN: 0027-8874 *
CARLISLE ALEX J ET AL: "Development of a prostate cDNA microarray and statistical gene expression analysis package.", MOLECULAR CARCINOGENESIS, vol. 28, no. 1, May 2000 (2000-05-01), pages 12 - 22, XP002225396, ISSN: 0899-1987 *
HOWELL S ET AL.: "DNA microarrays for analysis of gene expression in prostate cancer", MOLECULAR UROLOGY, vol. 3, no. 3, 1999, pages 295 - 302, XP001131993 *
MOUSSES S ET AL: "Functionnal genomics : gene expression analysis by cDNA microarrays", 2000, LIVESEY FJ AND HUNT SP (EDS) OXFORD UNIVERSITY PRESS, OXFORD, XP008011769 *
MOUSSES SPYRO ET AL: "Failure of hormone therapy in prostate cancer involves systematic restoration of androgen responsive genes and activation of rapamycin sensitive signaling.", ONCOGENE, vol. 20, no. 46, 11 October 2001 (2001-10-11), pages 6718 - 6723, XP001132000, ISSN: 0950-9232 *
NAKAJIMA HIDENORI ET AL: "New antitumor substances, FR901463, FR901464 and FR901465: II. Activities against experimental tumors in mice and mechanism of action.", JOURNAL OF ANTIBIOTICS (TOKYO), vol. 49, no. 12, 1996, pages 1204 - 1211, XP001109403, ISSN: 0021-8820 *
VAARALA M H ET AL: "Differentially expressed genes in two LNCaP prostate cancer cell lines", LABORATORY INVESTIGATION;A JOURNAL OF TECHNICAL METHODS AND PATHOLOGY. UNITED STATES AUG 2000, vol. 80, no. 8, August 2000 (2000-08-01), pages 1259 - 1268, XP002225395, ISSN: 0023-6837 *

Also Published As

Publication number Publication date
WO2002031209A2 (en) 2002-04-18
AU2002214576A1 (en) 2002-04-22

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