HK1050491A1 - Antibody dye conjugates for binding to target structures of angiogenesis in order to intraoperatively depict tumor periopheries - Google Patents

Antibody dye conjugates for binding to target structures of angiogenesis in order to intraoperatively depict tumor periopheries

Info

Publication number
HK1050491A1
HK1050491A1 HK03102709A HK03102709A HK1050491A1 HK 1050491 A1 HK1050491 A1 HK 1050491A1 HK 03102709 A HK03102709 A HK 03102709A HK 03102709 A HK03102709 A HK 03102709A HK 1050491 A1 HK1050491 A1 HK 1050491A1
Authority
HK
Hong Kong
Prior art keywords
periopheries
intraoperatively
angiogenesis
binding
order
Prior art date
Application number
HK03102709A
Inventor
Michael Schirner
Kai Licha
Ludger Dinkelborg
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7924318&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1050491(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Ag filed Critical Schering Ag
Publication of HK1050491A1 publication Critical patent/HK1050491A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0058—Antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032—Methine dyes, e.g. cyanine dyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0039—Coumarin dyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0041—Xanthene dyes, used in vivo, e.g. administered to a mice, e.g. rhodamines, rose Bengal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0041—Xanthene dyes, used in vivo, e.g. administered to a mice, e.g. rhodamines, rose Bengal
    • A61K49/0043—Fluorescein, used in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
HK03102709A 1999-09-24 2003-04-15 Antibody dye conjugates for binding to target structures of angiogenesis in order to intraoperatively depict tumor periopheries HK1050491A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19947559A DE19947559A1 (en) 1999-09-24 1999-09-24 Antibody-dye conjugates against target structures of angiogenesis for intraoperative tumor border imaging
PCT/EP2000/008121 WO2001023005A1 (en) 1999-09-24 2000-08-19 Antibody dye conjugates for binding to target structures of angiogenesis in order to intraoperatively depict tumor peripheries

Publications (1)

Publication Number Publication Date
HK1050491A1 true HK1050491A1 (en) 2003-06-27

Family

ID=7924318

Family Applications (1)

Application Number Title Priority Date Filing Date
HK03102709A HK1050491A1 (en) 1999-09-24 2003-04-15 Antibody dye conjugates for binding to target structures of angiogenesis in order to intraoperatively depict tumor periopheries

Country Status (23)

Country Link
EP (2) EP1214099A1 (en)
JP (1) JP2003510294A (en)
KR (2) KR100832937B1 (en)
CN (1) CN1269530C (en)
AU (1) AU779026B2 (en)
BG (1) BG65682B1 (en)
BR (1) BR0014192A (en)
CA (1) CA2385593A1 (en)
CZ (1) CZ2002991A3 (en)
DE (1) DE19947559A1 (en)
EE (1) EE05176B1 (en)
HK (1) HK1050491A1 (en)
HU (1) HUP0202625A2 (en)
IL (2) IL148405A0 (en)
MX (1) MXPA02002639A (en)
NO (1) NO20021441L (en)
NZ (1) NZ517944A (en)
RO (1) RO121598B1 (en)
RU (1) RU2002109237A (en)
SK (1) SK3972002A3 (en)
WO (1) WO2001023005A1 (en)
YU (1) YU20702A (en)
ZA (1) ZA200203225B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003524018A (en) 2000-02-24 2003-08-12 アイトゲネーシシェ テクニシェ ホッホシューレ チューリッヒ Antibodies specific for the ED-B domain of fibronectin, complexes containing said antibodies, and uses thereof for detecting and treating angiogenesis
US6440389B1 (en) * 2000-07-19 2002-08-27 The General Hospital Corporation Fluorescent agents for real-time measurement of organ function
AT413487B (en) * 2002-08-12 2006-03-15 Igeneon Krebs Immuntherapie USE OF ANTIBODIES TO TUMOR ASSOCIATED ANTIGEN
NO20034351D0 (en) * 2003-09-29 2003-09-29 Amersham Health As Optical imaging of endometriosis
ATE374367T1 (en) * 2004-07-22 2007-10-15 Bayer Schering Pharma Ag USE OF CYANINE DYES FOR DIAGNOSING DISEASES ASSOCIATED WITH ANGIOGENESIS
EP1679082A1 (en) * 2005-01-07 2006-07-12 Schering AG Use of cyanine dyes for the diagnosis of proliferative diseases
US20120041305A1 (en) * 2009-04-21 2012-02-16 The University Of Utah Research Foundation Light-emitting dye for intraoperative imaging or sentinel lymph node biopsy
WO2018026965A1 (en) * 2016-08-02 2018-02-08 Isi Life Sciences, Inc. Compositions and methods for detecting cancer cells in a tissue sample

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4341223A (en) * 1981-02-04 1982-07-27 Lutz Lauralee A Fluoresceable composition and method of determining fluid flow
WO1996001653A1 (en) * 1994-07-11 1996-01-25 Board Of Regents, The University Of Texas System Methods and compositions for the specific coagulation of vasculature
TWI259837B (en) * 1998-05-11 2006-08-11 Eidgenossische Tech Hochscule Specific binding molecules for scintigraphy, conjugates containing them and therapeutic method for treatment of angiogenesis

Also Published As

Publication number Publication date
KR20070087232A (en) 2007-08-27
NO20021441D0 (en) 2002-03-22
WO2001023005A1 (en) 2001-04-05
DE19947559A1 (en) 2001-04-19
CN1269530C (en) 2006-08-16
CA2385593A1 (en) 2001-04-05
NO20021441L (en) 2002-05-15
PL354027A1 (en) 2003-12-15
EE05176B1 (en) 2009-06-15
HUP0202625A2 (en) 2002-12-28
EE200200152A (en) 2003-04-15
RU2002109237A (en) 2003-11-27
KR100832937B1 (en) 2008-05-27
EP1532988A3 (en) 2008-09-17
EP1532988A2 (en) 2005-05-25
BG106528A (en) 2002-12-29
BR0014192A (en) 2002-05-21
BG65682B1 (en) 2009-06-30
IL148405A (en) 2009-06-15
IL148405A0 (en) 2002-09-12
CN1376074A (en) 2002-10-23
YU20702A (en) 2005-06-10
MXPA02002639A (en) 2002-07-30
ZA200203225B (en) 2003-07-23
CZ2002991A3 (en) 2002-06-12
AU779026B2 (en) 2005-01-06
JP2003510294A (en) 2003-03-18
RO121598B1 (en) 2007-12-28
SK3972002A3 (en) 2002-09-10
AU6702600A (en) 2001-04-30
NZ517944A (en) 2004-06-25
KR20020039349A (en) 2002-05-25
EP1214099A1 (en) 2002-06-19

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20100819