YU11402A - Nova primena docetaksela za lečenje hepatoma - Google Patents
Nova primena docetaksela za lečenje hepatomaInfo
- Publication number
- YU11402A YU11402A YU11402A YUP11402A YU11402A YU 11402 A YU11402 A YU 11402A YU 11402 A YU11402 A YU 11402A YU P11402 A YUP11402 A YU P11402A YU 11402 A YU11402 A YU 11402A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- docetaxel
- new use
- treating hepatoma
- hepatoma
- treating
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
Abstract
Ovaj pronalazak se zasniva na nalazu da je docetaksel znatno aktivniji protiv ćelija hepatoćelijskih karcinoma od paklitaksela pri koncentracijama do 1ВµM. Prema tome ovaj pronalazak daje primenu docetaksela ili njegovog hidrata u proizvodnji leka za primenu u lečenju hepatoćelijskog karcinoma.[The present invention is based on the finding that docetaxel is significantly more active against hepatocellular carcinoma cells than paclitaxel at concentrations of up to 1ВµM. It accordingly provides the use of docetaxel, or a hydrate thereof, in the manufacture of a medicament for use in the treatment of hepatocellular carcinoma.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9920548.6A GB9920548D0 (en) | 1999-08-31 | 1999-08-31 | Treatment of hepatocellular carcinoma |
Publications (2)
Publication Number | Publication Date |
---|---|
YU11402A true YU11402A (sh) | 2005-07-19 |
RS50148B RS50148B (sr) | 2009-05-06 |
Family
ID=10860081
Country Status (34)
Country | Link |
---|---|
US (2) | US20030158249A1 (sh) |
EP (1) | EP1214061B1 (sh) |
JP (1) | JP4866522B2 (sh) |
KR (1) | KR100670416B1 (sh) |
CN (1) | CN1174748C (sh) |
AT (1) | ATE269700T1 (sh) |
AU (1) | AU777583B2 (sh) |
BG (1) | BG65913B1 (sh) |
BR (1) | BR0013625A (sh) |
CA (1) | CA2382294C (sh) |
CZ (1) | CZ301378B6 (sh) |
DE (1) | DE60011794T2 (sh) |
DK (1) | DK1214061T3 (sh) |
EA (1) | EA004804B1 (sh) |
EE (1) | EE05124B1 (sh) |
ES (1) | ES2218223T3 (sh) |
GB (1) | GB9920548D0 (sh) |
HK (1) | HK1048944B (sh) |
HR (1) | HRP20020171A2 (sh) |
HU (1) | HU228861B1 (sh) |
IL (2) | IL147489A0 (sh) |
ME (1) | ME00624B (sh) |
MX (1) | MXPA02002041A (sh) |
NO (1) | NO328527B1 (sh) |
NZ (1) | NZ517604A (sh) |
PL (1) | PL212612B1 (sh) |
PT (1) | PT1214061E (sh) |
RS (1) | RS50148B (sh) |
SI (1) | SI1214061T1 (sh) |
SK (1) | SK286378B6 (sh) |
TW (1) | TW589180B (sh) |
UA (1) | UA72927C2 (sh) |
WO (1) | WO2001015675A2 (sh) |
ZA (1) | ZA200201408B (sh) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1268619C (zh) * | 2003-05-08 | 2006-08-09 | 上海迪赛诺化学制药有限公司 | 多烯紫杉醇三水化合物的制备方法 |
WO2005061474A1 (en) * | 2003-12-12 | 2005-07-07 | Quiral Química Do Brasil | Process for the preparation of anhydrous and hydrated active pharmaceutical ingredients (apis); stable pharmaceutical compositions prepared from the same and uses of said compositions |
US7449196B2 (en) * | 2004-07-09 | 2008-11-11 | Robert Sabin | Anti tumor compositions and methods of use |
CN103054798B (zh) * | 2005-08-31 | 2021-03-16 | 阿布拉科斯生物科学有限公司 | 用于制备稳定性增加的水难溶性药物的组合物和方法 |
NZ592132A (en) * | 2005-08-31 | 2012-12-21 | Abraxis Bioscience Llc | Composition comprising nanoparticles of docitaxel and a citrate |
US9839667B2 (en) | 2005-10-14 | 2017-12-12 | Allergan, Inc. | Prevention and treatment of ocular side effects with a cyclosporin |
US20080081051A1 (en) * | 2006-09-28 | 2008-04-03 | Robert Sabin | Method of manufacturing anti-tumor and anti-viral compositions |
EP2146695A4 (en) * | 2007-04-23 | 2010-05-19 | Sun Pharmaceuticals Ind Ltd | PHARMACEUTICAL COMPOSITIONS |
FR2917088B1 (fr) * | 2007-06-08 | 2009-09-04 | Aventis Pharma Sa | Dissolution directe du docetaxel dans un solvant dans le polysorbate 80 |
US8541360B2 (en) * | 2008-11-19 | 2013-09-24 | Ben Venue Laboratories, Inc. | Parenteral formulations comprising sugar-based esters and ethers |
PL2552438T3 (pl) | 2010-03-26 | 2016-12-30 | Sposoby leczenia raka wątrobowokomórkowego | |
CA2798180A1 (en) * | 2010-05-03 | 2011-11-10 | Teikoku Pharma Usa, Inc. | Non-aqueous taxane pro-emulsion formulations and methods of making and using the same |
US8842114B1 (en) | 2011-04-29 | 2014-09-23 | Nvidia Corporation | System, method, and computer program product for adjusting a depth of displayed objects within a region of a display |
JO3685B1 (ar) | 2012-10-01 | 2020-08-27 | Teikoku Pharma Usa Inc | صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها |
CA2976912A1 (en) * | 2015-02-17 | 2016-08-25 | Mallinckrodt Llc | Modified docetaxel liposome formulations and uses thereof |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2601675B1 (fr) * | 1986-07-17 | 1988-09-23 | Rhone Poulenc Sante | Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent |
FR2629819B1 (fr) * | 1988-04-06 | 1990-11-16 | Rhone Poulenc Sante | Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii |
US5543154A (en) * | 1991-12-27 | 1996-08-06 | Merck & Co., Inc. | Controlled release nifedipine delivery device |
JP3254219B2 (ja) * | 1993-01-19 | 2002-02-04 | ワーナー−ランバート・コンパニー | 安定な経口用のci−981製剤およびその製法 |
US5846945A (en) * | 1993-02-16 | 1998-12-08 | Onyx Pharmaceuticals, Inc. | Cytopathic viruses for therapy and prophylaxis of neoplasia |
US5436243A (en) * | 1993-11-17 | 1995-07-25 | Research Triangle Institute Duke University | Aminoanthraquinone derivatives to combat multidrug resistance |
FR2718963B1 (fr) * | 1994-04-25 | 1996-05-24 | Rhone Poulenc Rorer Sa | Nouvelle composition pharmaceutique à base de taxoïdes. |
FR2722191B1 (fr) * | 1994-07-08 | 1996-08-23 | Rhone Poulenc Rorer Sa | Procede de preparation du trihydrate du (2r,3s)-3-tertbutoxycarbonylamino-2-hydroxy-3-phenylpropionate de 4-acetoxy2alpha-benzoyloxy-5beta,20epoxy-1,7beta,10beta trihydroxy-9-oxo-tax-11-en-13alpha-yle |
US5968972A (en) | 1995-10-26 | 1999-10-19 | Baker Norton Pharmaceuticals, Inc. | Method for increasing the oral bioactivity of pharmaceutical agents |
US6245805B1 (en) * | 1995-10-26 | 2001-06-12 | Baker Norton Pharmaceuticals, Inc. | Method, compositions and kits for increasing the oral bioavailability of pharmaceutical agents |
FR2742751B1 (fr) * | 1995-12-22 | 1998-01-30 | Rhone Poulenc Rorer Sa | Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent |
CA2275889C (en) * | 1996-12-30 | 2008-03-18 | Battelle Memorial Institute | Formulation and method for treating neoplasms by inhalation |
US6503893B2 (en) * | 1996-12-30 | 2003-01-07 | Bone Care International, Inc. | Method of treating hyperproliferative diseases using active vitamin D analogues |
CN100462066C (zh) * | 1997-06-27 | 2009-02-18 | 美国生物科学有限公司 | 药剂的新制剂及其制备和应用方法 |
AU1146099A (en) * | 1997-09-18 | 1999-04-05 | Janssen Pharmaceutica N.V. | Fused imidazole derivatives for improving oral bioavailability of pharmaceuticalagents |
US6576660B1 (en) * | 1997-10-31 | 2003-06-10 | Arch Development Corporation | Methods and compositions for regulation of 5-α-reductase activity |
UA73092C2 (uk) * | 1998-07-17 | 2005-06-15 | Брістол-Майерс Сквібб Компані | Таблетка з ентеросолюбільним покриттям і спосіб її приготування |
CZ20012320A3 (cs) * | 1998-12-23 | 2002-10-16 | G. D. Searle & Co. | Léčivo s obsahem inhibitoru cyklooxygenázy-2 a jednoho nebo více antineoplastických činidel pro kombinační terapii při léčení neoplasie |
GB9909925D0 (en) * | 1999-04-29 | 1999-06-30 | Pharmacia & Upjohn Spa | Combined preparations comprising anthracycline derivatives |
US8080672B2 (en) * | 2005-12-13 | 2011-12-20 | Teva Pharmaceutical Industries Ltd. | Crystal form of atorvastatin hemi-calcium and processes for preparation thereof |
-
1999
- 1999-08-31 GB GBGB9920548.6A patent/GB9920548D0/en not_active Ceased
- 1999-09-22 TW TW088115041A patent/TW589180B/zh not_active IP Right Cessation
-
2000
- 2000-08-29 CA CA002382294A patent/CA2382294C/en not_active Expired - Fee Related
- 2000-08-29 RS YUP-114/02A patent/RS50148B/sr unknown
- 2000-08-29 DE DE60011794T patent/DE60011794T2/de not_active Expired - Lifetime
- 2000-08-29 UA UA2002021546A patent/UA72927C2/uk unknown
- 2000-08-29 KR KR1020027002446A patent/KR100670416B1/ko not_active IP Right Cessation
- 2000-08-29 EE EEP200200087A patent/EE05124B1/xx not_active IP Right Cessation
- 2000-08-29 PT PT00964144T patent/PT1214061E/pt unknown
- 2000-08-29 ES ES00964144T patent/ES2218223T3/es not_active Expired - Lifetime
- 2000-08-29 PL PL353198A patent/PL212612B1/pl unknown
- 2000-08-29 EA EA200200313A patent/EA004804B1/ru not_active IP Right Cessation
- 2000-08-29 EP EP00964144A patent/EP1214061B1/en not_active Expired - Lifetime
- 2000-08-29 WO PCT/EP2000/008782 patent/WO2001015675A2/en active IP Right Grant
- 2000-08-29 DK DK00964144T patent/DK1214061T3/da active
- 2000-08-29 IL IL14748900A patent/IL147489A0/xx active IP Right Grant
- 2000-08-29 SK SK271-2002A patent/SK286378B6/sk not_active IP Right Cessation
- 2000-08-29 HU HU0203197A patent/HU228861B1/hu not_active IP Right Cessation
- 2000-08-29 AT AT00964144T patent/ATE269700T1/de active
- 2000-08-29 CN CNB008114501A patent/CN1174748C/zh not_active Expired - Fee Related
- 2000-08-29 BR BR0013625-5A patent/BR0013625A/pt not_active Application Discontinuation
- 2000-08-29 SI SI200030478T patent/SI1214061T1/xx unknown
- 2000-08-29 MX MXPA02002041A patent/MXPA02002041A/es active IP Right Grant
- 2000-08-29 AU AU75168/00A patent/AU777583B2/en not_active Ceased
- 2000-08-29 NZ NZ517604A patent/NZ517604A/en not_active IP Right Cessation
- 2000-08-29 JP JP2001519889A patent/JP4866522B2/ja not_active Expired - Fee Related
- 2000-08-29 CZ CZ20020739A patent/CZ301378B6/cs not_active IP Right Cessation
- 2000-08-29 ME MEP-2009-78A patent/ME00624B/me unknown
-
2002
- 2002-01-06 IL IL147489A patent/IL147489A/en not_active IP Right Cessation
- 2002-02-19 ZA ZA200201408A patent/ZA200201408B/xx unknown
- 2002-02-20 NO NO20020829A patent/NO328527B1/no not_active IP Right Cessation
- 2002-02-26 HR HR20020171A patent/HRP20020171A2/hr not_active Application Discontinuation
- 2002-02-27 US US10/083,565 patent/US20030158249A1/en not_active Abandoned
- 2002-02-28 BG BG106460A patent/BG65913B1/bg unknown
-
2003
- 2003-02-18 HK HK03101197.6A patent/HK1048944B/zh not_active IP Right Cessation
-
2007
- 2007-06-12 US US11/761,512 patent/US20080045584A1/en not_active Abandoned
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