WO2022096269A1 - Verfahren und vorrichtung zum herstellen eines blisterschlauches, sowie blisterschlauch - Google Patents
Verfahren und vorrichtung zum herstellen eines blisterschlauches, sowie blisterschlauch Download PDFInfo
- Publication number
- WO2022096269A1 WO2022096269A1 PCT/EP2021/079084 EP2021079084W WO2022096269A1 WO 2022096269 A1 WO2022096269 A1 WO 2022096269A1 EP 2021079084 W EP2021079084 W EP 2021079084W WO 2022096269 A1 WO2022096269 A1 WO 2022096269A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- blister
- packaging material
- bag
- cover
- area
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract description 20
- 239000005022 packaging material Substances 0.000 claims abstract description 122
- 239000000463 material Substances 0.000 claims abstract description 25
- 238000004519 manufacturing process Methods 0.000 claims abstract description 17
- 239000012780 transparent material Substances 0.000 claims abstract description 8
- 238000012856 packing Methods 0.000 claims abstract 2
- 230000005540 biological transmission Effects 0.000 claims description 27
- 239000010410 layer Substances 0.000 claims description 26
- 230000002829 reductive effect Effects 0.000 claims description 7
- 238000011144 upstream manufacturing Methods 0.000 claims description 5
- 239000011241 protective layer Substances 0.000 claims description 3
- 230000004308 accommodation Effects 0.000 claims 2
- 238000007689 inspection Methods 0.000 abstract description 15
- 230000036961 partial effect Effects 0.000 abstract description 5
- 238000002834 transmittance Methods 0.000 abstract 2
- 239000003814 drug Substances 0.000 description 26
- 229940079593 drug Drugs 0.000 description 21
- 238000007493 shaping process Methods 0.000 description 3
- 239000003086 colorant Substances 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 238000004806 packaging method and process Methods 0.000 description 2
- 208000029257 vision disease Diseases 0.000 description 2
- 230000004393 visual impairment Effects 0.000 description 2
- 241000251468 Actinopterygii Species 0.000 description 1
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 230000003760 hair shine Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 229920001684 low density polyethylene Polymers 0.000 description 1
- 239000004702 low-density polyethylene Substances 0.000 description 1
- 229940126601 medicinal product Drugs 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B5/00—Packaging individual articles in containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, jars
- B65B5/10—Filling containers or receptacles progressively or in stages by introducing successive articles, or layers of articles
- B65B5/101—Filling containers or receptacles progressively or in stages by introducing successive articles, or layers of articles by gravity
- B65B5/103—Filling containers or receptacles progressively or in stages by introducing successive articles, or layers of articles by gravity for packaging pills or tablets
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B57/00—Automatic control, checking, warning, or safety devices
- B65B57/02—Automatic control, checking, warning, or safety devices responsive to absence, presence, abnormal feed, or misplacement of binding or wrapping material, containers, or packages
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B61/00—Auxiliary devices, not otherwise provided for, for operating on sheets, blanks, webs, binding material, containers or packages
- B65B61/02—Auxiliary devices, not otherwise provided for, for operating on sheets, blanks, webs, binding material, containers or packages for perforating, scoring, slitting, or applying code or date marks on material prior to packaging
- B65B61/025—Auxiliary devices, not otherwise provided for, for operating on sheets, blanks, webs, binding material, containers or packages for perforating, scoring, slitting, or applying code or date marks on material prior to packaging for applying, e.g. printing, code or date marks on material prior to packaging
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B9/00—Enclosing successive articles, or quantities of material, e.g. liquids or semiliquids, in flat, folded, or tubular webs of flexible sheet material; Subdividing filled flexible tubes to form packages
- B65B9/06—Enclosing successive articles, or quantities of material, in a longitudinally-folded web, or in a web folded into a tube about the articles or quantities of material placed upon it
- B65B9/08—Enclosing successive articles, or quantities of material, in a longitudinally-folded web, or in a web folded into a tube about the articles or quantities of material placed upon it in a web folded and sealed transversely to form pockets which are subsequently filled and then closed by sealing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B2220/00—Specific aspects of the packaging operation
- B65B2220/22—Interconnected packages concurrently produced from the same web, the packages not being separated from one another
Definitions
- the present invention relates to a method and a device for producing a blister tube and a blister tube.
- the invention relates to a method for producing a blister tube which can be provided with information over a large area and which is optimized for an inspector system, a blister tube, a corresponding device and a blister tube as such.
- a check can be carried out manually, namely by the individual blister bags of a blister tube being examined by a user, regularly with the support of an optical recording and reproduction system.
- the check can be carried out automatically, with a user only having to intervene if such bags are identified during the automated check where it cannot be clearly established that the correct drug portions are blistered. Since involving a user is time-consuming and costly, efforts are made to keep the number of blister bags that require a final check by a user as low as possible.
- An automatic control is carried out with so-called inspector systems.
- An example of such a system is disclosed, for example, in WO 2014/119994 A1.
- bag-specific data e.g. patient data
- other data e.g. information about the patient and the time of administration.
- the pouch-specific data are regularly applied to an outer area of the blister pouch.
- the imprint of the data is kept as small as possible in order not to negatively influence the control, i . H . that the printing as such is not understood as a portion of medicine and that a false positive is generated as a result. It is therefore to be avoided in any case that the applied bag-specific data is incorrectly interpreted by an automatic inspector system as a pharmaceutical portion arranged in the blister bag.
- a packaging material web is produced with a plurality of cover sections extending in the longitudinal direction of the packaging material web with a transmission of ⁇ 60% in the visible frequency range, a transparency material area extending in the longitudinal direction parallel to the cover sections with a transmission of > 80% in the visible frequency range and a
- a plurality of data sections are provided, bag-specific data is printed on a data section, a section of the packaging material web is formed into a receiving area, with each receiving area being assigned at least one cover section or at least a partial area thereof and the previously printed data section, small items are fed to the receiving area and Finally, a blister bag is formed from the receiving section containing small items.
- cover sections By providing a plurality of cover sections with a transmission of ⁇ 60% in the visible frequency range in the packaging material web, there is the possibility of providing these cover sections with large-area data that indicate, for example, the time at which the drug portions contained in a blister bag were taken.
- further data can be applied as an alternative or in addition, so it is also conceivable to apply advertising data, specifically in a large number of colors, without impeding the detection of the drug portions in the inspector system.
- a cover section can have a kind of mirror layer on the underside, which throws back the light that shines through a cover section
- the cover sections can be formed in such a way that they complement each other to form a continuous strip, i. H .
- the web of packaging material can, for example (viewed in the longitudinal direction) be formed half by cover sections and half by a transparency material area.
- the cover sections can only form repeating partial areas of one half of the web of packaging material—the rest of this half is then usually formed by a carrier or transparency material.
- cover sections depends crucially on the type of production - if they are, for example, only "manufactured" in a blister machine, they are usually applied to one half of a packaging material web made of a uniform carrier layer material, which usually also has a transmission > 80 % in the visible frequency range.
- a packaging material web made of a uniform carrier layer material, which usually also has a transmission > 80 % in the visible frequency range.
- cover sections can then, for example, form one half of the packaging material web.
- the data sections can be provided on the material area with a transmission of >80% in the visible frequency range, especially if they are arranged in an area that does not interfere with subsequent inspection.
- the method is preferably conducted in such a way that the data sections are provided on the cover sections, so that the applied data does not interfere with the inspection due to the low transmission of the cover sections can, regardless of the positioning of the data sections.
- the bag-specific data can be patient data, for example, or the bag-specific data can include them. However, it is also conceivable that the bag-specific data have no relation to a specific person, but are only based on the content and/or the time of administration.
- a large-area information unit can be applied to the cover sections, which does not interfere with checking the content of the blister bags in an inspector system if the process is carried out appropriately.
- the application of the information unit can already take place after the production of the packaging material web and the production of the cover sections.
- an information unit can be applied every x centimeters.
- each x-th cover section (possibly equivalent to every x-th bag) can be provided with a special information unit (e.g. time of administration: morning, noon, evening).
- the information unit can be printed, for example.
- the application of the information unit directly after production of the packaging material web leads to the fact that the packaging material web cannot be used flexibly without the positioning of the if necessary. to change large-scale information unit in the resulting blister bags. For example, it is not possible to produce blister bags of different lengths without moving the positioning of the information unit on the blister bags produced.
- a cover section is provided with an information unit in such a way that the information unit is arranged on the outside of the blister bag to be formed, and the contents of the blister bag are thereby checked in the inspector system then not disturbs when the inspection is carried out from the side opposite the imprint from the transparency material area of the original packaging material web.
- This procedure has the advantage that the application of the information unit can be adapted to the length of the blister bag to be produced, which in turn can be adapted to the quantity and/or size of the drug portions to be introduced.
- a cover section bag-specific fish data retrieved or. are received and applying the information unit to a cover section is performed on the basis of the data.
- clearly recognizable information units can be applied to people with visual impairments, which provide information about the intake time of the pharmaceutical portions arranged in a blister bag. If corresponding information units are already applied during the production of the packaging material web, Empty bags are produced when only blister bags for a morning and evening intake are produced for one user, but blister bags for a three-time intake per day for another user.
- the cover sections can be provided during the production of the packaging material web. This means that the cover sections are identical for the entire web of packaging material.
- a preferred embodiment of the method according to the invention is characterized in that the packaging material web is provided with a plurality of cover sections extending in the longitudinal direction of the packaging material web, in that a layer with reduced transparency (with a transmission ⁇ 60% in the visible frequency range) is applied.
- the cover section can only shortly before applying the possibly large-scale information unit are produced, and can be adapted to the way of application. So it is also conceivable for the cover sections to be designed in accordance with the bag-specific data, for example choosing a special color for a special administration time.
- a preferred embodiment provides for the layer with reduced transparency to be produced by printing a colored layer or applying a cover layer to the carrier layer material area, whereby it is possible from the point of view of Simplicity of the device is particularly preferred that the layer is printed with reduced transmission.
- a preferred embodiment of the method provides for at least the cover sections to be covered with a protective layer after an information unit has been applied.
- the object is also achieved by a device for producing a blister tube according to claim 7, which can be provided with information over a large area and which is optimized for an inspector system.
- the device according to the invention comprises a printing device coupled to a control device for applying bag-specific data to a data section of a packaging material web, an application device coupled to a control device for applying an information unit to a cover section of a packaging material web, a packaging material guiding device arranged upstream of the printing and application devices for Recording a packaging material web with a plurality of cover sections extending in the longitudinal direction of the packaging material web with a transmission of ⁇ 60% in the visible frequency range, a Transparency material area extending in the longitudinal direction parallel to the cover sections with a transmission of > 80% in the visible frequency range and a plurality of data sections, the packaging material web guiding device being designed in such a way that the data sections are assigned to the printing device and the cover sections are assigned to the application device or are fed, a packaging material forming device for receiving the packaging material web, the
- the device according to the invention can be used to produce blister tubes with blister bags provided with information units over a large area, which are suitable for an inspector system despite the information units, since the web of packaging material is guided in such a way that the information units are applied to the non-transparent cover sections.
- the device comprises a cover section device arranged upstream of the application device for applying the several cover sections.
- a cover section device arranged upstream of the application device for applying the several cover sections.
- "normal" packaging material in which no cover sections are provided which are not transparent to visible light.
- a normal web of packaging material can also be used to produce blister bags.
- each blister bag has a receiving area for small items, in which the drug portions of an assembly are arranged after the blister bag has been formed.
- Each blister bag comprises at least one data section and a cover section as well as a transparent material area arranged opposite a cover section with a transmission of >80% in the visible frequency range, with the cover section covering the receiving section in such a way that all small items arranged in the receiving space can be covered.
- the blister tube is characterized in that the cover section has a transmission of ⁇ 60% in the visible frequency range.
- the cover sections are not transparent to visible light, but are permeable to light in the near infrared range.
- a particularly preferred embodiment of the blister tube provides for the data section and the cover section of a blister bag to be arranged on the same side.
- Figures 1a and 1b show oblique views of a first preferred embodiment of the device, with a packaging material web being omitted in Figure 1a,
- FIGS. 2a and 2b show a plan view and a rear view of the first embodiment
- Figure 3 shows a schematic view of a second embodiment of the device according to the invention
- Figures 4a and 4b illustrate a section of the method according to the invention, with different embodiments being illustrated in Figures 4a and 4b
- Figure 5 illustrates an inspection of a known blister bag with large-area printing
- Figure 6 illustrates an inspection of a blister bag of a blister tube according to the invention
- Figures 7a and 7b show side views of a blister tube according to the invention
- FIGS. 8a-8d schematically illustrate different structures of a packaging material web.
- FIGS. 1a and 1b show oblique views of a first embodiment of the device 1 according to the invention, a web of packaging material being omitted in FIG. 1a in order not to cover other components of the device.
- the embodiment shown in FIGS. 1a and 1b largely corresponds to the device disclosed in EP 3 385 174 A1, the disclosure content of which is hereby incorporated into this application.
- the embodiment of the device according to the invention shown in Figures la and 1b comprises a packaging material forming device 50 which forms an elongated packaging material web (see Figures 2a and 2b) into a receiving area 43 indicated in Figure 1b for medicinal product portions and in a running direction of the packaging material web continues .
- the device also includes a joining device 60, 70 for joining the formed packaging material web into one Blister bag of a blister tube, this joining device comprising a longitudinal joining device 60 and a transverse joining device 70 in the embodiment shown, which are designed as separate components in the embodiment shown.
- this joining device can also be constructed differently, see for example EP 3 045 397 A1.
- the packaging material forming device 50 acts together with a drug portion feed 80 which is arranged above the packaging material forming device 50 .
- the packaging material shaping device 50 has a shoulder-like surface 51 which shapes the packaging material web in such a way that the receiving area 43 is formed.
- a transverse joining region 44 is indicated below the receiving region 43 , in which the web of packaging material is joined with joining means 71 , 72 of the transverse joining device 70 .
- the joining means 72 can be moved horizontally and is moved up after the transverse joining region has been joined, so that the web of packaging material can be guided further in the running direction.
- EP 3 385 174 A1 European patent application EP 3 385 174 A1.
- the device 1 comprises a first printing device 10 and a Application device 20 , which in the embodiment shown is also designed as a (second) pressure device, the pressure devices being arranged one behind the other in the embodiment shown.
- the two pressure devices in the embodiment shown are arranged “at the back” of the device, one behind the other in such a way that both pressure devices are assigned to one half of the elongated packaging material web 40, specifically the one with the cover sections 41.
- upstream of the printing devices is a packaging material guide device 30 for receiving a packaging material web 40 with a plurality of cover sections 41 extending in the longitudinal direction of the packaging material web 40 with a transmission ⁇ 60% in the visible frequency range and a transparency material region 49 with a transmission of >80% in the visible frequency range extending in the longitudinal direction parallel to the cover sections 41.
- cover sections 41 On the cover sections 41 is a plurality of data sections 42, which are spaced apart in the longitudinal direction from the transparency be rich 49 extend, arranged .
- the cover sections and the data sections are arranged in such a way that the cover sections and data sections are on the "same side" of the packaging material web and the transparency material area 49 is completely free of information of any kind, so that the inspection as little as possible
- the data section can also be provided on the side with the transparent material area, as is illustrated further below.This is particularly conceivable if the data is only arranged very small in the outer area of a subsequent bag.
- the guide device is designed merely as a deflection roller. If the device has a different route for the packaging material web or a differently provided packaging material web is used, it may be necessary to use a more complex packaging material guiding device, i . H . depending on the arrangement of the printing devices and the manner in which the packaging material web is stored, the guide device must be adapted accordingly. For example, it is conceivable that the web of packaging material is already stored folded along the longitudinal axis, so that the web of packaging material guiding device is then to be designed in such a way that the cover and data sections then lying opposite are fed to correspondingly arranged printing devices.
- a web of packaging material which has a plurality of cover sections 41 extending in the longitudinal direction and a plurality of data sections 42 .
- the cover sections are arranged in such a way that they enclose the complete “left” half of the packaging material web and form a continuous cover layer on which the data sections are provided.
- the “right” side is covered by a transparent Material area formed.
- the cover sections are formed, for example, as repeating sections of the left-hand section of the web of packaging material; between the deck sections sections of carrier or Extend Transparency Material .
- the data sections 42 are those areas of the web of packaging material which are intended for later printing with patient information. These can be specially marked, but it can also be the case that they only define a predetermined area in a section of the packaging material web, ie they do not include any physical characteristics on the packaging material web.
- FIG. 3 shows a greatly simplified, schematic illustration of an embodiment of the device according to the invention
- FIGS. 4a and 4b show partial areas of others Embodiments, with FIG. 4b showing a first and second printing device one behind the other and FIG. 4a also showing a cover section device 100, which is designed as a third printing device.
- FIGS. 3, 4a and 4b show a greatly simplified, schematic illustration of an embodiment of the device according to the invention
- FIGS. 4a and 4b show partial areas of others Embodiments, with FIG. 4b showing a first and second printing device one behind the other and FIG. 4a also showing a cover section device 100, which is designed as a third printing device.
- a packaging material web 40 is provided by means of a packaging material web roll 90, in the present case without a preforming of the packaging material web, ie. H .
- the packaging material web 40 is provided without any folding on the packaging material web roll 90 .
- the packaging material web is arranged on the packaging material web roll, for example already pre-folded along the longitudinal axis.
- the packaging material web 40 provided comprises a plurality of cover sections 41 extending in the longitudinal direction of the packaging material web and a plurality of data sections 42 which, in the embodiment according to Figure 4b, are spaced apart in the longitudinal direction from the Deck sections extend.
- the web of packaging material does not yet include any cover sections 41 ; these are only applied using a cover section device 100 configured as a third printing device.
- the cover sections can also be applied as non-transparent film sections or (possibly already printed) stickers.
- the cover sections 41 can be seen in the lower half of the packaging material web 40, with these cover sections forming a continuous cover section region without interruption in the embodiment shown.
- the dashed vertical lines indicated in FIG. 4b are only intended to indicate the area in which the formed web of packaging material 40 is later joined.
- the "upper" half of the packaging material web is through a Transparency material area 49 formed with a transmission of> 80% in the visible frequency range.
- the packaging material web 40 is fed from the packaging material web roll 90 via a packaging material web guide device 30 to a first printing device 10, bag-specific data 47 being applied to a data section 42 in the printing device 10, as indicated in FIGS. 4a and 4b.
- the two pressure devices 10, 20 are not arranged next to one another, but one behind the other. Downstream of the first printing device 10 there is an application device 20 designed as a second printing device, with which in the embodiment shown according to FIGS such that the print is placed on the outside of the blister bag to be subsequently formed.
- the situation is such that the blister bag is folded after the application of the bag-specific data 47 and the imprints on the center line of the web of packaging material, so that both imprints are automatically arranged on the outside.
- the web of packaging material 40 is fed via a deflection roller 91 to a web of packaging material forming device 50, which forms the web of packaging material into a receiving area in such a way that it is suitable for receiving small piece goods .
- the receiving area 43 is supplied with 80 medicament portions via a medicament portion feeder.
- a blister bag 3 of a blister tube 2 is formed from a receiving area by means of a joining device 60 , 70 , in that the web of packaging material is joined together by means of the joining device, for example by the action of heat.
- the joining device can have a transverse joining device 70 and a Longitudinal joining device 60 include, as in Figures la - 2b is indicated.
- the exact design of the joining device is not essential for the present invention.
- the post-forming guidance of the packaging web is not essential; FIG. 3 shows, for example, that the web of packaging material is guided horizontally, whereas vertical guidance was provided in the previous figures. The precise guidance of the packaging material web and the assembly of this into a blister bag depends on the precise design of the device with regard to these components, but is not essential to the invention.
- FIG. 4b shows the pressure range of a further embodiment of the device according to the invention and of the method according to the invention.
- a cover section device 100 designed as a third printing device is provided, with which the cover sections 41 are applied to the packaging material web 40 .
- the web of packaging material with the several cover sections is provided by actively applying the cover sections; a web of packaging material that already has these cover sections is not used.
- this increases the structural complexity of the device, it is possible, for example, to generate cover sections of different sizes, shapes or colors, for example by supplying the third printing device with patient-specific printing information.
- the section of the packaging material web to which the cover sections are applied is formed by a carrier layer material region 48 .
- the "upper" section of the packaging material web is in turn formed by a transparency material area 49 with a transmission of >80% in the visible frequency range.
- the two transparency material areas 48, 49 are regularly made in one piece from the same material Material be made, d. H . a material with a transmission of > 80% in the visible frequency range.
- the data sections 42 are also arranged in the lower section, which can be seen in particular in the area of the third printing device.
- the cover sections are applied with the third printing device, the bag-specific data are applied with the first printing device 10 arranged downstream, and the information units 46 , here simple imprints, are applied to the cover sections 41 with the second printing device arranged downstream of the first printing device.
- FIG. 5 schematically illustrates an inspection of a blister bag 3 with two drug portions 4 and an imprint 46 on a transparent material 9 of a blister bag.
- the imprint 46 shown in the left image is recorded as an outline 5 'of a drug portion if a "conventional" blister bag 3 is used, which consists only of transparent material 9, and the inspection of the bag contents with visible
- two drug outlines 5 and one outline 5' of the imprint are determined for a blister bag 3 with only two drug portions 4 and an imprint 46, whereby three drug portions are detected during the inspection, although only two drug portions 4 are in the blister bag 3 are included.
- FIG. 6 shows the result of an inspection of a blister bag 3 with a cover section 41 .
- the imprint 46 is only shown in dashed lines in the illustration on the left in FIG. 6, since it cannot actually be seen in the top view shown. If the bag is inspected with visible light from "above” through the transparency material area 49 of the original packaging material web, the imprint 46 is not detected due to the reduced transparency of the cover section 41, so that the result (right illustration) is correctly recognized that two drug portions 4 are arranged in the blister bag 3 .
- FIGS. 7a and 7b show two views of a blister tube 2 according to the invention with a plurality of blister bags 3 which are printed over a large area and are optimized for an inspector system. Perforations 44 in transverse joining areas 45' can be seen in FIG. 7a, which separate the individual blister bags from one another.
- Each blister bag 3 comprises a receiving area 43 in which several medicament portions 4 are arranged.
- each blister bag comprises a data section 41 and a cover section, in which bag-specific data 47 and an imprint 46 are applied.
- a longitudinal joint area 45 can also be seen in the upper area of the blister tube.
- FIGS. 8a-8d each show a cross section through a web of packaging material 40 on the left and a section of a blister bag formed from the web of packaging material on the right, with the longitudinal joint area on the right and the folding area on the left being omitted.
- this comprises a lower inner layer 400 made, for example, of LDPE, a superordinate carrier layer 401 made of PET and in the "left" area a cover layer, which in the embodiment shown defines the cover section 41.
- the left The web of packaging material shown is shaped by means of a web of packaging material forming device in such a way that the web of packaging material is folded in the central region, resulting in a blister bag 3 as shown in sections on the right shown arrow, the cover layer 402 itself is arranged on the inside during folding, so that the cover section 41 is arranged "inside".
- the receiving area 43 is arranged between the folded areas of the packaging material web, and a drug portion 4 is arranged in it. from below” and printing "on” the cover section from above, the printing cannot be perceived as a supposed pharmaceutical portion during inspection due to the non-transparent cover section.
- Figures 8b to 8d show further embodiments of a web of packaging material that can be used according to the invention, with the cover layer 402 being covered by a protective layer 403 in Figure 8b, the cover layer being applied directly to the inner layer 400 in Figure 8c and the cover layer 402 in Figure 8d is formed directly on the inner layer 400, so that the blister bag "top” and "bottom” is only one layer each.
- cover sections 41 are already provided with the web of packaging material or are applied in the course of the method according to the invention depends on the exact method management.
- the exact application or design of the cover sections also depends on the process management; it is only essential that a cover section 41 covers the receiving area 43 of a blister bag, so that a possible imprint on or above the cover section when inspecting a blister bag is not perceived as a medicine portion or can be misinterpreted.
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- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Containers And Plastic Fillers For Packaging (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Packages (AREA)
- Container Filling Or Packaging Operations (AREA)
- Auxiliary Devices For And Details Of Packaging Control (AREA)
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202180075289.1A CN116472224A (zh) | 2020-11-09 | 2021-10-20 | 用于制造泡罩管的方法和设备及泡罩管 |
KR1020237015950A KR20230101825A (ko) | 2020-11-09 | 2021-10-20 | 블리스터 튜브를 생산하기 위한 방법 및 장치, 그리고 블리스터 튜브 |
JP2023527229A JP2023547541A (ja) | 2020-11-09 | 2021-10-20 | ブリスターチューブの製造方法および装置、ならびにブリスターチューブ |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP20206458.0A EP3995401A1 (de) | 2020-11-09 | 2020-11-09 | Verfahren und vorrichtung zum herstellen eines blisterschlauches, sowie blisterschlauch |
EP20206458.0 | 2020-11-09 |
Publications (1)
Publication Number | Publication Date |
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WO2022096269A1 true WO2022096269A1 (de) | 2022-05-12 |
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PCT/EP2021/079084 WO2022096269A1 (de) | 2020-11-09 | 2021-10-20 | Verfahren und vorrichtung zum herstellen eines blisterschlauches, sowie blisterschlauch |
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EP (1) | EP3995401A1 (ko) |
JP (1) | JP2023547541A (ko) |
KR (1) | KR20230101825A (ko) |
CN (1) | CN116472224A (ko) |
WO (1) | WO2022096269A1 (ko) |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2013034504A1 (en) | 2011-09-09 | 2013-03-14 | Carefusion Switzerland 317 Sàrl | System and method for packaging dosed quantities of solid drug portions |
US20140318078A1 (en) * | 2012-01-11 | 2014-10-30 | Panasonic Healthcare Co., Ltd. | Drug supply device and drug inspection method in drug supply device |
EP3045397A1 (de) | 2015-01-16 | 2016-07-20 | CareFusion Germany 326 GmbH | Verpackungsvorrichtung für Arzneimittel |
US20160304228A1 (en) * | 2015-04-17 | 2016-10-20 | Carefusion Germany 326 Gmbh | Apparatus for packaging individual medication doses and method for its operation |
EP3385174A1 (de) | 2017-04-07 | 2018-10-10 | Becton Dickinson Rowa Germany GmbH | Vorrichtung zum verpacken von arzneimittelportionen |
US10427810B2 (en) * | 2012-06-01 | 2019-10-01 | Rxsafe Llc | Pharmacy packaging system |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2951563B1 (en) | 2013-02-04 | 2019-12-11 | Ziuz Holding B.V. | Method and apparatus for inspecting packages containing medication |
-
2020
- 2020-11-09 EP EP20206458.0A patent/EP3995401A1/de active Pending
-
2021
- 2021-10-20 CN CN202180075289.1A patent/CN116472224A/zh active Pending
- 2021-10-20 JP JP2023527229A patent/JP2023547541A/ja active Pending
- 2021-10-20 KR KR1020237015950A patent/KR20230101825A/ko active Search and Examination
- 2021-10-20 WO PCT/EP2021/079084 patent/WO2022096269A1/de active Application Filing
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2013034504A1 (en) | 2011-09-09 | 2013-03-14 | Carefusion Switzerland 317 Sàrl | System and method for packaging dosed quantities of solid drug portions |
US20140318078A1 (en) * | 2012-01-11 | 2014-10-30 | Panasonic Healthcare Co., Ltd. | Drug supply device and drug inspection method in drug supply device |
US10427810B2 (en) * | 2012-06-01 | 2019-10-01 | Rxsafe Llc | Pharmacy packaging system |
EP3045397A1 (de) | 2015-01-16 | 2016-07-20 | CareFusion Germany 326 GmbH | Verpackungsvorrichtung für Arzneimittel |
US20160304228A1 (en) * | 2015-04-17 | 2016-10-20 | Carefusion Germany 326 Gmbh | Apparatus for packaging individual medication doses and method for its operation |
EP3385174A1 (de) | 2017-04-07 | 2018-10-10 | Becton Dickinson Rowa Germany GmbH | Vorrichtung zum verpacken von arzneimittelportionen |
Also Published As
Publication number | Publication date |
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KR20230101825A (ko) | 2023-07-06 |
CN116472224A (zh) | 2023-07-21 |
JP2023547541A (ja) | 2023-11-10 |
EP3995401A1 (de) | 2022-05-11 |
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