WO2020067618A8 - 알파-글루코시다제의 활성이 강화된 l-아미노산을 생산하는 미생물 및 이를 이용한 l-아미노산 생산 방법 - Google Patents

알파-글루코시다제의 활성이 강화된 l-아미노산을 생산하는 미생물 및 이를 이용한 l-아미노산 생산 방법 Download PDF

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WO2020067618A8
WO2020067618A8 PCT/KR2019/004228 KR2019004228W WO2020067618A8 WO 2020067618 A8 WO2020067618 A8 WO 2020067618A8 KR 2019004228 W KR2019004228 W KR 2019004228W WO 2020067618 A8 WO2020067618 A8 WO 2020067618A8
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amino acid
glucosidase activity
production method
same
acid production
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PCT/KR2019/004228
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French (fr)
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WO2020067618A1 (ko
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김경림
변효정
이광우
김형준
신용욱
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씨제이제일제당 (주)
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Priority to US16/484,315 priority Critical patent/US11293014B2/en
Priority to AU2019349396A priority patent/AU2019349396B2/en
Priority to JP2021510128A priority patent/JP7286758B2/ja
Priority to RU2019125582A priority patent/RU2732338C1/ru
Priority to CN201980001776.6A priority patent/CN111247250B/zh
Priority to BR112019019867-9A priority patent/BR112019019867B1/pt
Priority to PE2021000312A priority patent/PE20210686A1/es
Priority to EP19745962.1A priority patent/EP3656863A4/en
Application filed by 씨제이제일제당 (주) filed Critical 씨제이제일제당 (주)
Priority to MX2021002814A priority patent/MX2021002814A/es
Publication of WO2020067618A1 publication Critical patent/WO2020067618A1/ko
Publication of WO2020067618A8 publication Critical patent/WO2020067618A8/ko
Priority to PH12021550347A priority patent/PH12021550347A1/en
Priority to ZA2021/01456A priority patent/ZA202101456B/en
Priority to IL281567A priority patent/IL281567A/en

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    • C—CHEMISTRY; METALLURGY
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    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
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    • C12N15/09—Recombinant DNA-technology
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
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    • C12P13/00—Preparation of nitrogen-containing organic compounds
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    • C12P13/00—Preparation of nitrogen-containing organic compounds
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    • C12P13/00—Preparation of nitrogen-containing organic compounds
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    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/0102—Alpha-glucosidase (3.2.1.20)
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    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/15—Corynebacterium

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  • Chemical & Material Sciences (AREA)
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  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

본 출원은 α-글루코시다제 (α-Glucosidase)의 활성이 강화된 L-아미노산을 생산하는 미생물 및 이를 이용한 L-아미노산 생산 방법에 관한 것이다. 본 출원의 L-아미노산을 생산하는 코리네박테리움 속 미생물은 α-글루코시다제 활성이 강화되어, L-아미노산 생산 수율이 향상된 것이므로, 상기 미생물은 L-아미노산 생산 용도로 매우 유용하게 사용될 수 있다.
PCT/KR2019/004228 2018-09-28 2019-04-09 알파-글루코시다제의 활성이 강화된 l-아미노산을 생산하는 미생물 및 이를 이용한 l-아미노산 생산 방법 WO2020067618A1 (ko)

Priority Applications (12)

Application Number Priority Date Filing Date Title
PE2021000312A PE20210686A1 (es) 2018-09-28 2019-04-09 Microorganismo para la produccion de l-aminoacido con actividad mejorada de a-glucosidasa y procedimiento para la produccion de l-aminoacido usando el mismo
JP2021510128A JP7286758B2 (ja) 2018-09-28 2019-04-09 α－グルコシダーゼの活性が強化されたＬ－アミノ酸を生産する微生物及びそれを用いたＬ－アミノ酸生産方法
RU2019125582A RU2732338C1 (ru) 2018-09-28 2019-04-09 Микроорганизм для получения L-аминокислоты с повышенной активностью α-глюкозидазы и способ получения L-аминокислоты с его использованием
CN201980001776.6A CN111247250B (zh) 2018-09-28 2019-04-09 用于生产L-氨基酸的具有增强的α-葡萄糖苷酶活性的微生物和使用其生产L-氨基酸的方法
BR112019019867-9A BR112019019867B1 (pt) 2018-09-28 2019-04-09 Micro-organismo para produzir l-aminoácido com atividade aprimorada de a-glucosidase e método para produzir l-aminoácido com o uso do mesmo
US16/484,315 US11293014B2 (en) 2018-09-28 2019-04-09 Microorganism for producing L-amino acid with enhanced activity of α-glucosidase and method for producing L-amino acid using the same
EP19745962.1A EP3656863A4 (en) 2018-09-28 2019-04-09 MICROORGANISM FOR THE PRODUCTION OF L-AMINO ACID WITH INCREASED ACTIVITY OF ALPHA-GLUCOSIDASE AND A PROCESS FOR THE PRODUCTION OF L-AMINO ACID THEREOF
AU2019349396A AU2019349396B2 (en) 2018-09-28 2019-04-09 Microorganism For Producing L-Amino Acid With Enhanced Activity Of α-Glucosidase And Method For Producing L-Amino Acid Using The Same
MX2021002814A MX2021002814A (es) 2018-09-28 2019-04-09 Microorganismo para la produccion de l-aminoacido con actividad mejorada de a-glucosidasa y procedimiento para la produccion de l-aminoacido usando el mismo.
PH12021550347A PH12021550347A1 (en) 2018-09-28 2021-02-18 MICROORGANISM FOR PRODUCING L-AMINO ACID WITH ENHANCED ACTIVITY OF a-GLUCOSIDASE AND METHOD FOR PRODUCING L-AMINO ACID USING THE SAME
ZA2021/01456A ZA202101456B (en) 2018-09-28 2021-03-03 Microorganism for producing l-amino acid with enhanced activity of α-glucosidase and method for producing l-amino acid using the same
IL281567A IL281567A (en) 2018-09-28 2021-03-16 Hyacinths with increased activity of alpha-glycosidase for the formation of L-type amino acids and methods for the generation of those amino acids by the hictinates

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2018-0116540 2018-09-28
KR1020180116540A KR102112240B1 (ko) 2018-09-28 2018-09-28 알파-글루코시다제의 활성이 강화된 l-아미노산을 생산하는 미생물 및 이를 이용한 l-아미노산 생산 방법

Publications (2)

Publication Number Publication Date
WO2020067618A1 WO2020067618A1 (ko) 2020-04-02
WO2020067618A8 true WO2020067618A8 (ko) 2020-09-24

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PCT/KR2019/004228 WO2020067618A1 (ko) 2018-09-28 2019-04-09 알파-글루코시다제의 활성이 강화된 l-아미노산을 생산하는 미생물 및 이를 이용한 l-아미노산 생산 방법

Country Status (15)

Country Link
US (1) US11293014B2 (ko)
EP (1) EP3656863A4 (ko)
JP (1) JP7286758B2 (ko)
KR (1) KR102112240B1 (ko)
CN (1) CN111247250B (ko)
AU (1) AU2019349396B2 (ko)
BR (1) BR112019019867B1 (ko)
CL (1) CL2021000629A1 (ko)
IL (1) IL281567A (ko)
MX (1) MX2021002814A (ko)
PE (1) PE20210686A1 (ko)
PH (1) PH12021550347A1 (ko)
RU (1) RU2732338C1 (ko)
WO (1) WO2020067618A1 (ko)
ZA (1) ZA202101456B (ko)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111944781A (zh) * 2020-09-03 2020-11-17 廊坊梅花生物技术开发有限公司 一种突变的高丝氨酸激酶及其应用
KR20220156323A (ko) * 2021-05-18 2022-11-25 씨제이제일제당 (주) Agl 단백질의 활성이 강화된, 아미노산을 생산하는 미생물 및 이를 이용한 아미노산 생산 방법

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EP3415622A1 (en) 2017-06-14 2018-12-19 Evonik Degussa GmbH Method for production of fine chemicals using a corynebacterium secreting modified alpha-1,6-glucosidases

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Publication number Publication date
US20210017510A1 (en) 2021-01-21
EP3656863A4 (en) 2021-04-14
AU2019349396A1 (en) 2021-04-15
PE20210686A1 (es) 2021-04-08
BR112019019867B1 (pt) 2022-05-10
JP7286758B2 (ja) 2023-06-05
MX2021002814A (es) 2021-05-12
WO2020067618A1 (ko) 2020-04-02
US11293014B2 (en) 2022-04-05
IL281567A (en) 2021-05-31
BR112019019867A2 (pt) 2021-04-13
JP2021534765A (ja) 2021-12-16
KR20200036647A (ko) 2020-04-07
AU2019349396B2 (en) 2023-04-13
KR102112240B1 (ko) 2020-05-18
CN111247250B (zh) 2022-07-05
EP3656863A9 (en) 2020-11-11
CN111247250A (zh) 2020-06-05
ZA202101456B (en) 2022-06-29
EP3656863A1 (en) 2020-05-27
CL2021000629A1 (es) 2021-09-24
PH12021550347A1 (en) 2021-10-04
RU2732338C1 (ru) 2020-09-15

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