WO2019164346A8 - L-트립토판을 생산하는 재조합 코리네형 미생물 및 이를 이용한 l-트립토판을 생산하는 방법 - Google Patents
L-트립토판을 생산하는 재조합 코리네형 미생물 및 이를 이용한 l-트립토판을 생산하는 방법 Download PDFInfo
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- WO2019164346A8 WO2019164346A8 PCT/KR2019/002236 KR2019002236W WO2019164346A8 WO 2019164346 A8 WO2019164346 A8 WO 2019164346A8 KR 2019002236 W KR2019002236 W KR 2019002236W WO 2019164346 A8 WO2019164346 A8 WO 2019164346A8
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- tryptophan
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
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- C12N9/10—Transferases (2.)
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1022—Transferases (2.) transferring aldehyde or ketonic groups (2.2)
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
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- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
- C12P13/227—Tryptophan
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y202/00—Transferases transferring aldehyde or ketonic groups (2.2)
- C12Y202/01—Transketolases and transaldolases (2.2.1)
- C12Y202/01001—Transketolase (2.2.1.1)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y401/00—Carbon-carbon lyases (4.1)
- C12Y401/03—Oxo-acid-lyases (4.1.3)
- C12Y401/03027—Anthranilate synthase (4.1.3.27)
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- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
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- Bioinformatics & Cheminformatics (AREA)
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- Plant Pathology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
본 출원은 유전자 조작기법을 이용한 재조합 L-트립토판을 생산하는 코리네박테리움속 미생물, 및 상기 미생물을 이용하여 L-트립토판을 생산하는 방법에 관한 것이다.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020180022057A KR102035844B1 (ko) | 2018-02-23 | 2018-02-23 | L-트립토판을 생산하는 재조합 코리네형 미생물 및 이를 이용한 l-트립토판을 생산하는 방법 |
| KR10-2018-0022057 | 2018-02-23 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2019164346A1 WO2019164346A1 (ko) | 2019-08-29 |
| WO2019164346A8 true WO2019164346A8 (ko) | 2020-09-24 |
Family
ID=63230232
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/KR2019/002236 WO2019164346A1 (ko) | 2018-02-23 | 2019-02-22 | L-트립토판을 생산하는 재조합 코리네형 미생물 및 이를 이용한 l-트립토판을 생산하는 방법 |
Country Status (2)
| Country | Link |
|---|---|
| KR (1) | KR102035844B1 (ko) |
| WO (1) | WO2019164346A1 (ko) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102035844B1 (ko) * | 2018-02-23 | 2019-10-23 | 씨제이제일제당 주식회사 | L-트립토판을 생산하는 재조합 코리네형 미생물 및 이를 이용한 l-트립토판을 생산하는 방법 |
| KR102205717B1 (ko) * | 2019-04-05 | 2021-01-22 | 씨제이제일제당 주식회사 | 신규 l-트립토판 배출 단백질 변이체 및 이를 이용한 l-트립토판을 생산하는 방법 |
| KR102221040B1 (ko) | 2019-05-09 | 2021-03-03 | 씨제이제일제당 주식회사 | L-아미노산을 생산하는 미생물 및 이를 이용한 l-아미노산을 생산하는 방법 |
| KR102278000B1 (ko) * | 2020-03-17 | 2021-07-15 | 씨제이제일제당 주식회사 | 프리페네이트 디하이드라타아제 활성 강화를 통한 l-트립토판을 생산하는 방법 |
| KR102284726B1 (ko) * | 2021-01-25 | 2021-08-02 | 씨제이제일제당 주식회사 | 신규한 타우토머레이즈 pptA 변이체 및 이를 이용한 L-트립토판 생산 방법 |
| KR102649245B1 (ko) | 2021-03-08 | 2024-03-21 | 씨제이제일제당 주식회사 | L-아미노산을 생산하는 코리네박테리움 속 미생물 및 이를 이용한 l-아미노산의 생산방법 |
| WO2023133484A1 (en) * | 2022-01-07 | 2023-07-13 | Ginkgo Bioworks, Inc. | Skin commensal bacteria engineered to produce anthranilate or derivatives thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60176593A (ja) | 1984-02-22 | 1985-09-10 | Kyowa Hakko Kogyo Co Ltd | Ｌ−トリプトフアンの製造法 |
| US7160711B2 (en) * | 2001-08-06 | 2007-01-09 | Degussa Ag | Coryneform bacteria which produce chemical compounds I |
| KR100792095B1 (ko) * | 2006-12-29 | 2008-01-04 | 씨제이 주식회사 | Ｌ-페닐알라닌 생산능을 갖는 대장균 변이주로부터유전자조작된 ｌ-트립토판 생산능을 갖는 재조합 대장균균주 및 이를 이용한 트립토판 제조방법 |
| ES2910377T3 (es) * | 2012-01-10 | 2022-05-12 | Cj Cheiljedang Corp | Microorganismos de Escherichia coli que tienen la producción de L-triptófano mejorada y método para producir L-triptófano mediante el uso de los mismos |
| JP6679803B2 (ja) * | 2016-08-31 | 2020-04-15 | シージェイ チェイルジェダン コーポレーション | 新規プロモーター及びその用途 |
| KR102035844B1 (ko) * | 2018-02-23 | 2019-10-23 | 씨제이제일제당 주식회사 | L-트립토판을 생산하는 재조합 코리네형 미생물 및 이를 이용한 l-트립토판을 생산하는 방법 |
-
2018
- 2018-02-23 KR KR1020180022057A patent/KR102035844B1/ko active IP Right Grant
-
2019
- 2019-02-22 WO PCT/KR2019/002236 patent/WO2019164346A1/ko active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| WO2019164346A1 (ko) | 2019-08-29 |
| KR20180089329A (ko) | 2018-08-08 |
| KR102035844B1 (ko) | 2019-10-23 |
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