WO2018227759A1 - Gelée de gingembre tranquillisante et son procédé de préparation - Google Patents

Gelée de gingembre tranquillisante et son procédé de préparation Download PDF

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Publication number
WO2018227759A1
WO2018227759A1 PCT/CN2017/098857 CN2017098857W WO2018227759A1 WO 2018227759 A1 WO2018227759 A1 WO 2018227759A1 CN 2017098857 W CN2017098857 W CN 2017098857W WO 2018227759 A1 WO2018227759 A1 WO 2018227759A1
Authority
WO
WIPO (PCT)
Prior art keywords
ginseng
cream
paste
schisandra chinensis
schisandra
Prior art date
Application number
PCT/CN2017/098857
Other languages
English (en)
Chinese (zh)
Inventor
武传毅
Original Assignee
武传毅
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 武传毅 filed Critical 武传毅
Publication of WO2018227759A1 publication Critical patent/WO2018227759A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7016—Disaccharides, e.g. lactose, lactulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/57—Magnoliaceae (Magnolia family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/79—Schisandraceae (Schisandra family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

Definitions

  • the invention relates to the field of traditional Chinese medicine health care products, in particular to a ginseng anshen cream and a preparation method thereof, in particular to a ginseng cream and a preparation method thereof, which are mainly raw materials of fresh ginseng and Schisandra chinensis.
  • Traditional Chinese medicines have a variety of traditional unilateral, prescription, prescription and modern proprietary Chinese medicines for regulating sleep, or they are different from traditional Chinese medicine in syndrome differentiation and treatment, depending on the syndrome, more consideration, more complicated syndromes, no specific effect, and less stable than stability. Factors such as low cost and convenience are not well understood and accepted by the public. In fact, many Chinese patent medicines have a good effect, but the effect period is long.
  • the drugs used to treat insomnia are very rich, and there are many plants that can be used as medicines and health products, which is worthy of research and development.
  • the causes of insomnia are mainly visceral disorders, especially the warming and yang function of the heart and the yin function of the kidney can not be coordinated, qi and blood deficiency, yin and yang disorders, etc., but in the field of traditional Chinese medicine health products, There are very few health products that are effective and effective in improving human immunity and regulating sleep quality.
  • the present invention provides a fresh ginseng and schisandra chinensis as the main raw material and is made of earth rock sugar, which is prepared by the method of traditional Chinese medicine cream and has reasonable cost and can improve human immunity.
  • the invention adopts the following technical scheme, a ginseng Anshen ointment, which is prepared by the following components using a traditional Chinese medicine ointment method: ginseng 5%-10%, Schisandra chinensis 15%-25%, earth rock sugar 65%-75% The sum of the percentages of the contents of the components is equal to 100%.
  • the ratio of the raw materials of the paste is 9%-10% of ginseng, 23%-25% of Schisandra chinensis, 65%-70% of earth rock sugar, and the sum of the percentages of the contents of each component is equal to 100%.
  • the ginseng is fresh ginseng.
  • Fresh ginseng is nearly 30% higher than ginsenosides in dry ginseng, and fresh ginseng is planted for a longer period of time. The longer the ginseng is planted, the better the quality.
  • ginseng It can improve the adaptability of the body and has a good regulation effect on the cardiovascular system, liver, endocrine system and material metabolism. Modern medicine believes that the pharmacological action of ginseng also includes the regulation of nerve function, which can restore the nervous process caused by tension.
  • the ginsenoside Rb in ginseng has a central sedative effect, Rb1, Rb2, and Rc have a calming effect; Rg has a central excitatory effect.
  • the effect of ginsenoside on the central center is small dose excitation and large dose inhibition.
  • fresh ginseng is immersed in a water body and pulverized into a slurry by a wet pulverization method. This will preserve more of the active substance in fresh ginseng.
  • Schisandra is made of Schisandra chinensis.
  • Schisandra has a distinction between north and south, modern pharmacological analysis, the pharmacology of Schisandra chinensis and Schisandra chinensis are different.
  • Schisandra contains Schisandrin C23H3206 and vitamin C, resin, tannin and a small amount of sugar.
  • Chinese medicine believes that Schisandra is similar to ginseng in adapting to the original effect, and has the effects of concentrating lung, nourishing kidney, producing fluid, sweating, and phlegm; ginseng and schisandra are complemented.
  • the pharmacological effects of modern medicine on it: Schisandra can enhance the body's defense ability against non-specific stimuli; increase cellular immune function, and significantly increase the activity of SOD in brain, liver and spleen, so it has the effect of improving immunity, anti-oxidation and anti-aging. .
  • Schisandra has a good antibacterial effect, and it has inhibitory effects on common Staphylococcus aureus, Klebsiella pneumoniae, Salmonella enterica, and Pseudomonas aeruginosa. Also, Schisandrin has a wide central inhibitory effect and is characterized by a calming action.
  • the invention also protects the preparation method of the ginseng Anshen cream, comprising the following steps:
  • decoction soaked in cold water for 6-8 hours, use the decoction machine to take the conventional decoction method, cook twice, and then let it stand, then take the supernatant through a 30 mesh sieve to remove the seeds of Schisandra chinensis. ;
  • the supernatant is taken through a 30 mesh sieve to remove the seeds of Schisandra chinensis in the medicinal juice, so as to avoid the numbness of the sesame and stomach of the seeds of the Schisandra chinensis, and also improve the taste of the cream.
  • the smoldering temperature is below 70 °C.
  • the conventional decoction method adopts a decoction machine as a conventional decoction method, and a non-extraction method.
  • the ginseng Anshen cream of the invention is prepared by using fresh ginseng and schisandra chinensis as the main material, and the earth rock sugar is made by the method of traditional Chinese medicine cream.
  • the wet pulverization process in the Chinese patent medicine industry is adopted, and the preparation process of the modern paste is used to optimize the proportion of the raw materials in the paste, so that the nutritional content of the cream is sufficient, the quality is stable, the taste is unique and suitable for the public, and the human immunity is effectively improved. Force, regulate the role of sleep.
  • Embodiment 1 (manually controlled)
  • the fresh ginseng pulp and the schisandra supernatant are evenly mixed, and the boiling liquid is concentrated. After the water is boiled, the simmer is used for more than 2 hours.
  • the paste is transferred to the canister and naturally cools down. It takes about 1.5 hours.
  • the fresh ginseng pulp and the schisandra supernatant are evenly mixed, and the boiling liquid is concentrated. After the water is boiled, the simmer is used for more than 1 hour.
  • the paste is transferred to the canister and naturally cools down. It takes about 1.5 hours.
  • the fresh ginseng pulp and the Schisandra chinensis supernatant are evenly mixed, and the decoction liquid is concentrated. After the water boils, the simmer is used for more than 1.5 hours.
  • the paste is transferred to the canister and naturally let cool. The time is about 1.5 hours. After the coolness, the paste is purple and the paste is tight.
  • the formula of the present invention has accumulated feedback information of nearly 1,000 users (subsequent sub-health populations and insomniacs).
  • the feedback information is concentrated in:
  • Regular dose 1 500 grams of cream was taken for 12 days; deep sleep on the sixth day, resulting in the first time to work late for many years.
  • the second bottle of 500 grams of paste continued to take, during which the user's physical and mental state is very good, but the quality of sleep has been repeated, after understanding: the user has a large amount of pepper in his daily diet.
  • the sleep quality of the user is obviously improved, the state is stable, and the body function is improved significantly, mainly in the enhancement of digestion and absorption function, more than one year. I have never had a cold.
  • Regular dose 2 500 grams of cream is taken for 20 days; after 12 days, the user requests to stop taking it. According to his own summary: At present, you can eat and sleep, and have a tendency to gain weight.

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)

Abstract

L'invention concerne une gelée de ginseng tranquillisante et son procédé de préparation. Du ginseng frais et du Schisandra chinensis sont utilisés comme matières premières principales. L'utilisation d'un procédé de broyage par voie humide relevant de l'industrie des médicaments brevetés chinois en coopération avec un procédé de préparation de formule de gelée moderne permet d'optimiser les proportions des matières premières d'une formule de gelée classique, de façon que la gelée préparée contienne des composants nutritionnels suffisants, ait une qualité stable et un goût unique, se prête à la production de masse, et ait pour fonctions d'améliorer l'immunité chez l'homme, de favoriser le sommeil et autres.
PCT/CN2017/098857 2017-06-13 2017-08-24 Gelée de gingembre tranquillisante et son procédé de préparation WO2018227759A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201710442523.5A CN107224480A (zh) 2017-06-13 2017-06-13 一种人参安神膏及其制备方法
CN201710442523.5 2017-06-13

Publications (1)

Publication Number Publication Date
WO2018227759A1 true WO2018227759A1 (fr) 2018-12-20

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PCT/CN2017/098857 WO2018227759A1 (fr) 2017-06-13 2017-08-24 Gelée de gingembre tranquillisante et son procédé de préparation

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WO (1) WO2018227759A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110237153A (zh) * 2019-07-29 2019-09-17 北京本草方源药业集团有限公司 一种复合颗粒剂及其制备方法

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1682833A (zh) * 2005-02-24 2005-10-19 北京正大绿洲医药科技有限公司 人参五味子滴丸及其制备方法
CN103131571A (zh) * 2013-03-18 2013-06-05 鞍山聚缘食品有限公司 五味子人参酒及其制备方法
CN104419608A (zh) * 2013-08-28 2015-03-18 青岛医防消毒专业技术中心 一种五味子山楂酒
CN104419577A (zh) * 2013-08-28 2015-03-18 青岛医防消毒专业技术中心 五味子葡萄酒
CN106540077A (zh) * 2015-09-23 2017-03-29 雷新民 一种治疗失眠的组合物中药
CN106692650A (zh) * 2015-07-22 2017-05-24 姚军 一种治疗失眠的组合物中药

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1679849A (zh) * 2005-01-12 2005-10-12 杜洪录 人参营养冲剂

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1682833A (zh) * 2005-02-24 2005-10-19 北京正大绿洲医药科技有限公司 人参五味子滴丸及其制备方法
CN103131571A (zh) * 2013-03-18 2013-06-05 鞍山聚缘食品有限公司 五味子人参酒及其制备方法
CN104419608A (zh) * 2013-08-28 2015-03-18 青岛医防消毒专业技术中心 一种五味子山楂酒
CN104419577A (zh) * 2013-08-28 2015-03-18 青岛医防消毒专业技术中心 五味子葡萄酒
CN106692650A (zh) * 2015-07-22 2017-05-24 姚军 一种治疗失眠的组合物中药
CN106540077A (zh) * 2015-09-23 2017-03-29 雷新民 一种治疗失眠的组合物中药

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