WO2016182225A1 - Composition de prévention de la chute des cheveux et de stimulation de la croissance des cheveux - Google Patents

Composition de prévention de la chute des cheveux et de stimulation de la croissance des cheveux Download PDF

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Publication number
WO2016182225A1
WO2016182225A1 PCT/KR2016/004271 KR2016004271W WO2016182225A1 WO 2016182225 A1 WO2016182225 A1 WO 2016182225A1 KR 2016004271 W KR2016004271 W KR 2016004271W WO 2016182225 A1 WO2016182225 A1 WO 2016182225A1
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Prior art keywords
hair
weight
hair loss
parts
hair growth
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PCT/KR2016/004271
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English (en)
Korean (ko)
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장정훈
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주식회사 제이코스메틱스
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Priority to CN201680041388.7A priority Critical patent/CN107847401A/zh
Publication of WO2016182225A1 publication Critical patent/WO2016182225A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9728—Fungi, e.g. yeasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9755—Gymnosperms [Coniferophyta]
    • A61K8/9767—Pinaceae [Pine family], e.g. pine or cedar
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9794—Liliopsida [monocotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth

Definitions

  • the present invention relates to a hair loss prevention and hair growth composition, and more particularly, a natural fermented product and butyl avocate (Bentonite), chitosan (Chitosan), avocado fruit (Avocado) to promote fermentation by combining Butyl Avocadate), biotin (Biotin), natural ingredients extracts, and vitamins as an active ingredient, to prevent hair loss and hair growth composition.
  • a natural fermented product and butyl avocate Bentonite
  • Chitosan Chitosan
  • avocado fruit Avocado
  • Biotin biotin
  • Hair loss from the scalp is a very common disease, and mental stress caused by hair loss degrades the quality of life and affects a lot of relationships and social life.
  • the causes of hair loss are variously estimated, mainly due to genetic factors such as excessive secretion of testosterone, endocrine system disorders, excessive sebum production due to circulatory disorders such as blood circulation disorders, deterioration of scalp function due to allergy, bacterial infection, hair root Nutrient deficiency, various pollution, shampoo, hair spray, perm, dyeing, hair dryer and other environmental factors caused by the use, and aging and stress are believed to be a complex action.
  • hair loss occurred mainly in middle and middle aged people, but recently, hair and scalp damage caused by mousse, perm, dyeing, and dry heat, and increased social and environmental stress.
  • hair loss occurs notably in young people in their 20s and 30s due to food changes due to westernization of their eating habits, and also increases in female type hair loss as well as male type hair loss.
  • Minoxidil a form applied to the scalp that is currently used as a hair regrowth, has been developed as a hypertension treatment to dilate blood vessels in the past, but it has capillary expansion function to prevent hair loss when applied to the scalp, but it must be prescribed for a long time.
  • the drug remains in the scalp for some time to have some effect, and other side effects such as hair growth, rash, inflammation, and itching may occur at the site of application.
  • Propecia which is used for the treatment of enlarged prostate, is based on the side effect of promoting hair growth after taking it, and it inhibits the production of dihydrotestosterone (DHT), a male hormone that causes hair loss, and male hair loss.
  • DHT dihydrotestosterone
  • DHT dihydrotestosterone
  • the compounds include cyclosporin derivatives (Republic of Korea Patent Registration 10-0439467, Republic of Korea Patent Registration 10-0695611), Digestalis (International Patent Publication WO 2010/004303), Oxalate (International) Patent Document WO 1994/015574), and herbal extracts include extracts of orchidaceae plants (Korea Patent Registration 10-0157667), half, clove, bokbunja, Sancho, Manza, Dansam and white porcelain extract (Korea Patent Registration 10- 259037) have been reported.
  • the present invention was derived to solve the above problems, to provide a hair loss prevention and hair growth composition using environmentally friendly natural ingredients to inhibit the action of male hormones associated with alopecia and to provide nutrition to the scalp and hair hair To promote growth, and to activate the metabolism of the scalp tissue to provide a hair loss prevention and hair growth composition using a natural derived component having the effect of hair loss prevention and hair growth.
  • the hair loss prevention and hair growth composition according to the present invention is aged by mixing butyl avocadodate and biotin in a natural fermented product by mixing bentonite, chitosan and avocado fruit to promote hair growth. Characterized in that it comprises as an active ingredient.
  • 1 to 5 parts by weight of butyl avocadodate and 0.1 to 3 parts by weight of biotin are added to 5 to 15 parts by weight of fermented natural fermented product by mixing bentonite, chitosan and avocado fruit at a weight ratio of 2 to 4: 1: 1. It is characterized in that it comprises a mixture by aging as an active ingredient.
  • the hair loss prevention and hair growth composition according to the present invention is characterized in that it further comprises at least one or more components selected from the group consisting of natural ingredient extracts, vitamins, glutathione.
  • the natural ingredient extract may be any one extracted from natural ingredients having hair loss prevention and hair growth effects, preferably green tea, octagonal fennel, grapefruit, lotus, peony root, golden, medicinal herbs, ginseng, sewage, yeast, jojoba Group consisting of seeds, hawthorn, walnuts, avocado fruit, aloe vera leaf, chamomile flower, nettle, elder fruit, chrysanthemum flower, hibiscus fruit, cypress leaf, celery, white paper, sessin, mulberry root, nasturtium, lavender It is characterized in that the extract extracted from one or more natural ingredients selected from.
  • the natural ingredient extract is characterized in that it comprises 50 to 80 parts by weight.
  • the vitamin may be any compound as long as it can be blended into the hair loss preventing and hair growth composition according to the present invention, and preferably, water-soluble or fat-soluble vitamins may be included.
  • the vitamin is characterized in that it comprises 3 to 10 parts by weight.
  • the hair loss prevention and hair growth composition according to the present invention is characterized in that it comprises 0.1 to 3 parts by weight of glutathione.
  • the hair loss prevention and hair growth composition according to the present invention with the above configuration, there is no side effect even if used for a long time by using eco-friendly natural ingredients, excellent hair loss prevention and hair growth effect, both male and female, infants Safe compositions can be provided.
  • the hair loss prevention and hair growth composition according to the present invention there is also a sedative effect of preventing the stimulation as a stress applied to the hair and the scalp and the resulting inflammation, dandruff, hair loss and the like repeatedly dyed, perm.
  • Bentonite, chitosan, and avocado fruit that promote hair growth are mixed in 5 to 15 parts by weight of natural fermented product by fermentation in a weight ratio of 2 to 4: 1: 1, 1 to 5 parts by weight of butyl campuse, and 0.1 to 3 parts by weight of biotin Hair loss prevention and hair growth composition comprising a mixture of aging as an active ingredient
  • Hair loss prevention and hair growth composition according to the present invention is 5 to 15 parts by weight of a fermented natural fermentation blended bentonite, chitosan, avocado fruit to promote hair growth in a weight ratio of 2-4: 1: 1 butyl avocadodate 1 5 parts by weight, 0.1 to 3 parts by weight of biotin is mixed and aged as an active ingredient.
  • bentonite refers to clay containing abundant minerals such as calcium, potassium, and zinc, and is mainly composed of montmorillonite (Montmorillonite) having high surface area due to crystal structure such as mica and having high adsorption and reactivity.
  • the colors are very diverse, including grayish white, pale yellow and red yellow.
  • Chitosan is a component found in shells of crustaceans such as crabs and shrimps, and grasshoppers, and its molecular structure, which is chemically combined with a polysaccharide substance called glucosamine, is very similar to our human tissues. It is a highly versatile ingredient. Chitosan is absorbed by the hair to regulate the balance of moisture and fat in the cell membrane, to create a moisturizing film to protect the hair, to soothe sensitive scalp to prevent hair loss and reduce dandruff.
  • avocado is a fruit that is also called plant butter because it contains a large amount of unsaturated fatty acids such as omega-3, and is rich in flavonoids, vitamins, minerals, folic acid, and dietary fiber, which is beneficial for skin health including scalp and reducing blood cholesterol It is a natural food that has an excellent effect on.
  • fermentation and aging can be used to extract a significant amount of active ingredients such as vitamins, potassium, calcium, minerals, chitosan oligosaccharides, flavonoids, and the like to promote hair growth.
  • active ingredients such as vitamins, potassium, calcium, minerals, chitosan oligosaccharides, flavonoids, and the like to promote hair growth. The growth effect can be obtained.
  • the natural fermentation product included in the hair loss prevention and hair growth composition according to the present invention is a mixture of bentonite, chitosan, and avocado fruit in a weight ratio of 2 to 4: 1: 1, and the pulverized pulverized product is 14 at a fermentation temperature of 20 to 37 ° C. After fermentation for 21 days, 1 to 5 parts by weight of butyl avocadodate and 0.1 to 3 parts by weight of biotin are mixed with 5 to 15 parts by weight of the filtered natural fermentation product.
  • the strain input amount is preferably only 0.2 to 1 parts by weight of bentonite, chitosan, avocado fruit blend to be mixed with its own microorganisms contained in each component so that the natural fermentation can be made together.
  • Fermentation liquid may be oxidized if it is exposed to direct sunlight during fermentation.It is preferable to ferment it away from direct sunlight.After fermentation is completed, the properties of natural fermentation may change depending on time, temperature, light, etc. It is aged for 10-30 days under the condition that temperature condition is maintained. If the aging temperature is too high, it is difficult to ripen for a long time, and if the aging temperature is too low, it is not suitable due to poor ripening, so for the extraction of the active ingredient, it is preferable to keep the aging temperature continuously at 15 to 20 ° C, and the duration is 10 It is preferable to allow aging for ⁇ 30 days.
  • the natural fermentation product included in the hair loss prevention and hair growth composition according to the present invention is preferably included in 5 to 15 parts by weight, when less than 5 parts by weight is not satisfactory hair loss and hair growth effect is not satisfactory, if it exceeds 15 parts by weight Compared to the amount used, the effect of preventing hair loss and increasing hair growth is insignificant and it is uneconomical in terms of product stability.
  • the mature product of butyl avocadodate and biotin mixed with the natural fermentation inhibits the action of 5-alpha reductase, which inhibits the conversion of testosterone to DHT and excessive secretion of hair follicle sebaceous glands. Has been shown to promote hair growth.
  • Butyl avocadodate contained in the hair loss preventing and hair growth composition according to the present invention is preferably included in the skin conditioning agent 1 to 5 parts by weight, biotin containing the vitamin component is preferably included in 0.1 to 3 parts by weight.
  • the hair loss prevention and hair growth composition according to the present invention further comprises at least one or more components selected from the group consisting of 50 to 80 parts by weight of natural ingredient extract, 3 to 10 parts by weight of vitamin, or 0.1 to 3 parts by weight of glutathione. will be.
  • the natural ingredient extract according to the present invention may be any one extracted from natural ingredients having hair loss prevention and hair growth effects, but preferably green tea, octagonal fennel, grapefruit, lotus, peony root, golden, medicinal herbs, ginseng, sewage, Yeast, jojoba seed, hawthorn, walnut, avocado fruit, aloe vera leaf, chamomile flower, nettle, elder fruit, chrysanthemum flower, turnipberry fruit, western cypress leaf, cheongung, white paper, sessin, mulberry root, nasturtium, lavender It is characterized in that at least one extract selected from the group consisting of.
  • the natural ingredient extracts of the present invention extracted from them also have no problems such as toxicity and side effects. Can be used with confidence. Efficacy of the natural ingredients of the present invention is roughly smooth blood circulation, warm the body, has an excellent effect on the treatment of inflammation of the scalp, inhibits the activity of bacteria, such as dandruff, maintains a healthy scalp state, skin tissue And healthy hair roots to prevent hair loss and help hair growth.
  • the natural extract according to the present invention is selected from the group consisting of water, ethanol, methanol, propanol, butanol, acetone, ethyl acetate, hexane, butylene glycol, propylene glycol, hydrobutylene glycol, hydrous propylene glycol, hydrous glycerin Extraction using one or more solvents, but preferably using water or 60% to 90% ethanol, and most preferably hot water extraction using water.
  • each natural ingredient is dried to a water content of 0.1 to 1% by weight through a washing and cutting process, and then pulverized into a 100 to 200 mesh using a pulverizer to prepare a pulverized product, based on 1 kg of the pulverized product After adding 0.5 to 5 times the volume of water to the concentration of 12 to 36 hours at a temperature of 80 ⁇ 100 °C, it can be compressed to obtain an extract.
  • the natural ingredient extract may be prepared using ethanol, for example, by adding ethanol in a volume of about 2 to 10 times based on 1 kg of crushed natural ingredients and extracting by stirring for 6 to 24 hours The extract can be obtained by removing the residue using filter paper.
  • Each natural ingredient extract thus prepared is preferably frozen and stored after extraction, and may be used by mixing during preparation of the hair loss prevention and hair growth composition according to the present invention.
  • the vitamin according to the present invention may be any one as long as it can be blended into the hair loss prevention and hair growth composition, but preferably a water-soluble or fat-soluble vitamin.
  • the efficacy of the vitamin of the present invention has been shown to improve hair health by improving scalp cells to strengthen the scalp and inhibiting androgen receptors to strengthen the hair root.
  • Preferred water-soluble vitamins of the present invention include vitamin B1 (Thiamin), vitamin B2 (Riboflabin), pyridoxine, pyridoxine hydrochloride, vitamin B12, pantothenic acid, nicotinic acid, nicotinic acid amide, folic acid, vitamin C, vitamin H, and the like. Salts (thiamine hydrochloride, sodium ascorbate salt, etc.) and derivatives (ascorbic acid-2-sodium phosphate salt, ascorbic acid-2-magnesium phosphate salt, etc.) are also included in the water-soluble vitamins usable in the present invention.
  • the water-soluble vitamins can be obtained by conventional methods such as microbial transformation, purification from microorganism culture, enzyme or chemical synthesis.
  • preferred fat-soluble vitamins of the present invention include vitamin A, carotene, vitamin D2, vitamin D3, vitamin E (d1-alpha tocopherol, d-alpha tocopherol, d-alpha tocopherol), and derivatives thereof.
  • Corbin ascorbate stearate, ascorbine dipalmitate, acetic acid dl-alpha tocopherol, nicotinic acid dl-alpha tocopherolvitamin E, dl-pantothenyl alcohol, D-pantothenyl alcohol, pantothenylethyl ether, etc.
  • Fat-soluble vitamins can be obtained by conventional methods such as microbial transformation, purification from microorganism culture, enzyme or chemical synthesis.
  • the vitamin according to the present invention is preferably contained in 3 to 10 parts by weight, less than 3 parts by weight of the scalp or hair root strengthening effect is not satisfactory hair loss and hair growth effect is not satisfactory, when exceeding 10 parts by weight compared to the amount used The increase in effect may be minimal.
  • Efficacy of glutathione of the present invention is to enhance the efficacy of other ingredients and improve scalp health, it is preferably included in 0.1 to 3 parts by weight.
  • the preferred dosage of the hair loss preventing and hair growth composition according to the present invention depends on the condition of the hair, the degree of hair loss, and the properties of the product, but may be appropriately selected by those skilled in the art.
  • the hair loss prevention and hair growth composition according to the present invention may be administered once a day or may be divided several times.
  • the dosage and the method of administration do not limit the scope of the present invention in any aspect.
  • the hair loss preventing and hair growth composition according to the present invention, other ingredients that can be used as herbal or pharmacologically may also be included within the range that does not affect the hair loss preventing and hair growth effects of the present invention. Of course.
  • Bentonite, chitosan, and avocado fruit were mixed and crushed in a weight ratio of 3: 1: 1, placed in a fermentation vessel, fermented at 25 ° C. for 15 days, and filtered through a 5000 mesh filter cloth to prepare 10 kg of natural fermented product.
  • the prepared natural fermented product was mixed with butyl avocadodate and biotin for each dose according to each embodiment and used for 15 days at a temperature of 18 ° C.
  • Bentonite, chitosan, and avocado fruit in the same manner as in Preparation Example 1 was mixed and crushed in a weight ratio of 3: 1: 1, and then filtered through a filter cloth to prepare a mixture, unlike in Preparation Example 1, the fermentation process was omitted.
  • the prepared comparative mixture was used by mixing with butyl avocadodate and biotin at the dose according to the examples.
  • a clinical evaluation of hair loss prevention and hair growth functionality was conducted in 36 subjects (18 males and 18 females) who had hair loss symptoms with the hair tonic prepared in Example.
  • Example 1 Example 2
  • Example 3 Example 4
  • Example 5 Comparative example Group average 2.8 3.5 4 4.3 4.3 2.6 male 3.0 3.7 4.3 4.3 4.3 2.6 female 2.6 3.3 3.7 4.3 4.3 2.6
  • Examples 2 to 5 which contain a natural fermentation product of fermentation and fermentation by mixing bentonite, chitosan, and avocado, have a good hair loss prevention effect compared to the comparative example in which the fermentation aging process is omitted.
  • Examples 2 to 5 containing 5 parts by weight or more compared to Example 1 containing less than 5 parts by weight of the fermentation, but showed a significant hair loss preventing effect, containing more than 15 parts by weight of natural fermentation
  • Example 5 it was confirmed that the increase of the anti-hair loss effect is insignificant compared to Example 4.
  • Example 1 Example 2
  • Example 3 Example 4
  • Example 5 Comparative example Group average 2.2 3.5 3.8 4.2 4.2 2.2 male 2.0 3.7 4.0 4.3 4.0 2.3 female 2.3 3.3 3.7 4.0 4.3 2.0
  • the evaluation score was lower than that of the hair loss prevention effect, but in Examples 2 to 5 containing natural fermentation fermented in the same manner, compared to the comparative example in which the fermentation aging process was omitted, there was a good hair growth effect. It was confirmed that the content of the natural fermentation was found to be good hair growth effect in Examples 2 to 5 5 parts by weight or more, Example 5 containing more than 15 parts by weight of the natural fermentation Example 2 It was confirmed that the increase of the hair growth effect is insignificant compared to 4 to 4.
  • Example 1 Example 2
  • Example 3 Example 4
  • Example 5 Comparative example Group average 3.0 4.2 4.5 4.6 4.5 2.5 male 3.0 4.3 4.6 4.6 4.6 2.6 female 3.0 4.0 4.3 4.6 4.3 2.3
  • the content of the natural fermentation was good to more than 5 parts by weight, but when the content of the natural fermentation exceeds 15 parts by weight it was confirmed that the increase of the effect is insignificant.
  • the present invention relates to the growth of hair and prevention of hair loss, and has industrial applicability.

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Abstract

La présente invention concerne une composition permettant de prévenir la chute des cheveux et stimulant la croissance des cheveux et, plus particulièrement, une composition permettant de prévenir la chute des cheveux et de stimuler la croissance des cheveux, contenant, en tant qu'ingrédients actifs, un produit fermenté naturel comprenant de la bentonite, du chitosane, et de l'avocat, favorisant la croissance des cheveux, qui sont mélangés, puis fermentés, de l'avocadate de butyle, de la biotine, un extrait d'ingrédient naturel, et des vitamines.
PCT/KR2016/004271 2015-05-13 2016-04-23 Composition de prévention de la chute des cheveux et de stimulation de la croissance des cheveux WO2016182225A1 (fr)

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CN201680041388.7A CN107847401A (zh) 2015-05-13 2016-04-23 防脱发及生发组合物

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KR1020150066970A KR101550179B1 (ko) 2015-05-13 2015-05-13 탈모방지 및 모발성장 조성물
KR10-2015-0066970 2015-05-13

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KR101658333B1 (ko) * 2016-03-31 2016-09-20 주식회사 뮤제코스메틱 Bca 복합 발효물 및 모낭줄기세포 추출물을 함유하는 탈모방지 및 모발성장 조성물
KR101835973B1 (ko) * 2016-05-18 2018-03-07 정소원 한약재를 이용한 탈모방지 및 발모촉진용 조성물 및 이의 제조방법
KR102005777B1 (ko) * 2017-12-11 2019-07-31 육상조 양모 및 발모 촉진과 탈모방지를 위한 조성물, 및 이를 포함하는 화장료
KR101913362B1 (ko) 2018-07-23 2019-01-14 애경산업(주) 유사 세라마이드를 함유하는 두피 및 모발 보습용 조성물
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