WO2013133289A1 - 自動血圧測定装置 - Google Patents

自動血圧測定装置 Download PDF

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Publication number
WO2013133289A1
WO2013133289A1 PCT/JP2013/056037 JP2013056037W WO2013133289A1 WO 2013133289 A1 WO2013133289 A1 WO 2013133289A1 JP 2013056037 W JP2013056037 W JP 2013056037W WO 2013133289 A1 WO2013133289 A1 WO 2013133289A1
Authority
WO
WIPO (PCT)
Prior art keywords
value
pulse wave
bag
compression
amplitude
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2013/056037
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English (en)
French (fr)
Japanese (ja)
Inventor
西林　秀郎
和也 佐田
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
A&D Holon Holdings Co Ltd
Original Assignee
A&D Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by A&D Co Ltd filed Critical A&D Co Ltd
Priority to EP13758330.8A priority Critical patent/EP2823758B1/en
Priority to US14/382,730 priority patent/US10292604B2/en
Priority to CN201380012303.9A priority patent/CN104159503B/zh
Publication of WO2013133289A1 publication Critical patent/WO2013133289A1/ja
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A61B5/022—Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers
    • A61B5/02233—Occluders specially adapted therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A61B5/02108—Measuring pressure in heart or blood vessels from analysis of pulse wave characteristics
    • A61B5/02116—Measuring pressure in heart or blood vessels from analysis of pulse wave characteristics of pulse wave amplitude
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A61B5/02141—Details of apparatus construction, e.g. pump units or housings therefor, cuff pressurising systems, arrangements of fluid conduits or circuits
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A61B5/022—Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers

Definitions

  • the present invention relates to an automatic blood pressure measurement device having a compression band wound around a compression site that is a limb of a living body such as an arm or an ankle, and in particular, based on a pulse wave signal obtained from the compression band, It relates to the technology to be determined.
  • An object of the present invention is to provide an automatic blood pressure measurement device capable of determining a highly accurate systolic blood pressure value based on a pulse wave obtained when an artery in a compressed part of a living body is compressed. is there.
  • the pulse wave generated in the uppermost air chamber propagates to the adjacent air chamber by physical interference (crosstalk), and the adjacent middle air flow chamber and downstream air chamber
  • An interfering pulse wave attenuated at a predetermined attenuation rate is generated at the same time, but when the cuff pressure is reduced and blood flow is started, the volume pulse wave generated by the volume change due to the blood flow is generated in the middle flow chamber and the downstream air chamber. Is generated including the interference pulse wave.
  • the amplitude of the volume pulse wave tends to be slightly larger than that of the interference pulse wave, stable discrimination is difficult only by the amplitude difference indicating the amplitude.
  • the gist of the invention according to claim 1 is that: (a) a compression band wound around a compressed part of a living body, and pressure vibration in the compression band in the process of changing the compression pressure value of the compression band Is an automatic blood pressure measurement device that sequentially extracts a pulse wave and determines a blood pressure value of the living body based on a change in the pulse wave, and (b) the compression band is connected in the width direction to (C) ⁇ upstream inflation located upstream of the artery in the to-be-compressed portion of the plurality of inflatable bags, each having an independent air chamber that compresses each to-be-compressed portion Sequentially calculate the amplitude ratio of the amplitude value of the pulse wave from the predetermined expansion bag located downstream of the upstream expansion bag to the amplitude value of the pulse wave from the bag, and the amplitude ratio is set in advance The highest blood of the living body based on exceeding the ratio change judgment value It is to determine the value.
  • the gist of the invention according to the second aspect wherein the pressure value of the pressure band that has been boosted is set to the upstream expansion bag, the intermediate expansion bag, and the downstream side.
  • the value obtained by dividing the amplitude value of the pulse wave from the upstream expansion bag by the amplitude value of the pulse wave from the upstream expansion bag is made as the maximum blood pressure value of the living body based on the compression pressure value of the intermediate expansion bag when a certain third amplitude ratio exceeds a preset third amplitude ratio change determination value.
  • the compression pressure value of the intermediate expansion bag when the value is exceeded is determined as the maximum blood pressure value of the living body. For this reason, the blood flow of the artery in the compressed site passes under the upstream inflation bag but does not pass under the intermediate inflation bag and / or the downstream inflation bag, and the blood flow of the artery in the compressed site is predetermined. Distinguish between the state that passes under the inflatable bag and the downstream inflatable bag, and the blood flow of the artery in the compression site passes through the upper inflatable bag, the intermediate inflatable bag, and / or the downstream inflatable bag together Since the compression pressure value of the compression band at this time is determined as the maximum blood pressure value of the living body, a highly accurate maximum blood pressure value can be obtained.
  • the compressed pressure value of the compressed compression band is compressed by the upstream expansion bag, the intermediate expansion bag, and the downstream expansion bag.
  • a value obtained by dividing the amplitude value of the pulse wave from the upstream inflation bag by the amplitude value of the pulse wave from the downstream inflation bag is set in advance.
  • the compression pressure value of the intermediate expansion bag when the amplitude ratio change determination value is exceeded is determined as the maximum blood pressure value of the living body. Therefore, the blood flow of the artery in the compressed site passes under the upstream inflation bag but does not pass under the downstream inflation bag, and the blood flow of the artery in the compressed site passes under the upstream inflation bag and the downstream inflation.
  • the pressure distribution is uniform in the width direction. Since the compression pressure value of the expansion bag is determined as the maximum blood pressure value of the living body, a highly accurate maximum blood pressure value can be obtained.
  • FIG. 6 is a diagram showing pulse wave signals from the plurality of inflation bags generated in the process in which the compression pressure values of the plurality of inflation bags are gradually reduced by the cuff pressure control means of FIG. 5, and the compression pressure value is 72 mmHg. It is a certain time.
  • the first pulse wave signal from the upstream inflation bag of the cuff band, the second pulse wave signal from the intermediate inflation bag, and the shape of the third pulse wave signal from the downstream inflation bag It is a figure demonstrated in contrast with the compression state of the artery directly under an upstream expansion bag, an intermediate
  • the rising point of the pulse wave signal SM3 from the downstream expansion bag 26 shown in the two-dimensional coordinates of the time axis and the compression pressure value axis as shown in FIG.
  • the second time difference t21 from the rising point a1 of the pulse wave signal SM1 from the expansion bag 22, and the rising point a3 of the pulse wave signal SM3 from the downstream expansion bag 26 and the upstream expansion bag 22 Sequentially calculates the pulse wave signal SM1 and the third time difference t31 between the rising point a1 respectively.
  • the first time difference t32, the second time difference t21, and the third time difference t31 correspond to the phase difference.
  • the rising point a1 is an intersection of the tangent line Lt1 at the inflection point b1 of the rising portion of the pulse wave signal SM1 and the horizontal line Lw1 parallel to the time axis passing through the rising start point c1 of the pulse wave signal SM1.
  • the rising point a2 is the intersection of the tangent line Lt2 at the inflection point b2 at the rising portion of the pulse wave signal SM2 and the horizontal line Lw2 parallel to the time axis passing through the rising start point c2 of the pulse wave signal SM2.
  • FIG. 20, FIG. 21, and FIG. 22 are a flowchart and a time chart for explaining a main part of the control operation of the electronic control unit 70.
  • a power switch (not shown) is turned on, an initial state shown at time t0 in FIG.
  • the first on-off valve E1, the second on-off valve E2, the third on-off valve E3, and the quick exhaust valve 52 are normally open valves, they are in an open state (non-operating state), and the exhaust control valve 54 is in a normal state. Since it is closed, it is in a closed state (non-operating state), and the air pump 50 is in a non-operating state.
  • step the compression pressure value of the compression band 12 is increased.
  • the quick exhaust valve 52 is closed, and the air pump 50 is activated, and the compressed air fed from the air pump 50 is compressed into the main pipe 56 and to it.
  • the pressure in the inflated bladders 22, 24, and 26 communicated is rapidly increased.
  • compression of the upper arm 10 by the compression band 12 is started.
  • the operation of the air pump 50 is stopped in S3 corresponding to the cuff pressure control means 82.
  • the exhaust control valve 54 is configured so that the compression pressure values PC1, PC2, and PC3 of the boosted expansion bags 22, 24, and 26 are simultaneously reduced at a slow speed reduction rate that is preset to 3 to 5 mmHg / sec, for example. Is activated and slow exhaust is started. At this time, the exhaust control valve 54 is controlled so that the pressure reduction amount of the compression pressure value PC of the expansion bags 22, 24, and 26 becomes a predetermined amount within a range of 1 to 10 mmHg, for example.
  • FIGS. 6 to 11 are diagrams illustrating the first pulse wave signal SM1, the second pulse wave signal SM2, and the third pulse wave signal SM3 that are extracted and stored.
  • the pulse wave data used for determining the systolic blood pressure value is limited to pulse wave data not less than a preset lower limit value of, for example, about 100 mmHg or more.
  • the pulse wave data after the inflection point b1 of the first pulse wave signal SM1 that is, the actual data is limited to the data shown on the right side of the inflection point b1 in FIGS. .
  • FIG. 1 the pulse wave data after the inflection point b1 of the first pulse wave signal SM1 that is, the actual data is limited to the data shown on the right side of the inflection point b1 in FIGS. .
  • the compression pressure range of the pulse wave data used for determining the diastolic blood pressure value is limited to an upper limit value of, for example, about 100 mmHg. .
  • the pulse wave propagation velocity PWV is calculated by dividing the calculated first time difference t32 by the distance in the width direction between the intermediate expansion bag 24 and the downstream expansion bag 26, and as shown in FIG.
  • the pressure band T1, T2, and T3 that detects the pressure in the plurality of inflatable bags 22, 24, and 26, and is wound around the upper arm 10
  • each compression pressure value PC is held for a predetermined time every predetermined amount of deceleration pressure reduction within a range of 1 to 10 mmHg, and the first expansion bag 22, the second expansion bag 24, and the third expansion bag are held within the predetermined time.
  • the pressure increase target pressure value PCM and the measurement end pressure value PCE are not necessarily preset.
  • the input systolic blood pressure value SBP has a predetermined value (for example, 30 mmHg).
  • the measurement end pressure value PCE may be set to a value obtained by subtracting a predetermined value (for example, 30 mmHg) from the input minimum blood pressure value DBP.
  • the blood pressure value is determined while the pressure in the compression band 12 is decreased.
  • the present invention is not limited to this, and the process in which the pressure in the compression band 12 is increased.
  • the pressurization measurement for determining the blood pressure value may be performed. In such a pressure increase measurement, the above-described systolic blood pressure value determination algorithm and diastolic blood pressure value determination algorithm can be used, and similar effects can be obtained.
  • the amplitude values A1, A2, and A3 of the pulse wave signals SM1, SM2, and SM3 synchronized with each other are converted into pulse values within one pulse wave.
  • the amplitude value A2 or A3 of the pulse wave signal SM2 or SM3 generated after the pulse wave signal SM1 for example, one beat may be used to obtain the amplitude ratio.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Physiology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dentistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
PCT/JP2013/056037 2012-03-06 2013-03-05 自動血圧測定装置 Ceased WO2013133289A1 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP13758330.8A EP2823758B1 (en) 2012-03-06 2013-03-05 Automatic blood pressure measurement device
US14/382,730 US10292604B2 (en) 2012-03-06 2013-03-05 Automatic blood pressure measurement device
CN201380012303.9A CN104159503B (zh) 2012-03-06 2013-03-05 自动血压测定装置

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2012-049799 2012-03-06
JP2012049799A JP6086647B2 (ja) 2012-03-06 2012-03-06 自動血圧測定装置

Publications (1)

Publication Number Publication Date
WO2013133289A1 true WO2013133289A1 (ja) 2013-09-12

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PCT/JP2013/056037 Ceased WO2013133289A1 (ja) 2012-03-06 2013-03-05 自動血圧測定装置

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US (1) US10292604B2 (enExample)
EP (1) EP2823758B1 (enExample)
JP (1) JP6086647B2 (enExample)
CN (1) CN104159503B (enExample)
WO (1) WO2013133289A1 (enExample)

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Publication number Priority date Publication date Assignee Title
WO2016205549A1 (en) * 2015-06-16 2016-12-22 Braintree Analytics Llc Cuff designs and methods
JP6635842B2 (ja) * 2016-03-25 2020-01-29 京セラ株式会社 血圧推定装置、血圧計、血圧推定システム、及び血圧推定方法
CN107440701A (zh) * 2016-05-31 2017-12-08 宜强科技股份有限公司 不具加压泵的穿戴式血压量测装置
JP6247735B2 (ja) * 2016-11-10 2017-12-13 株式会社エー・アンド・デイ 自動血圧測定装置
JP6829599B2 (ja) * 2016-12-28 2021-02-10 オムロン株式会社 脈波測定装置および脈波測定方法、並びに血圧測定装置
JP6747332B2 (ja) * 2017-02-16 2020-08-26 オムロンヘルスケア株式会社 血圧情報測定装置
CN107174230B (zh) * 2017-06-22 2023-10-03 深圳市普瑞拓科技有限公司 智能血压计及其血压计量方法
CN107374606B (zh) * 2017-07-28 2023-07-14 康泰医学系统（秦皇岛）股份有限公司 一种血压计及血压测量方法
EP3550328B1 (en) * 2018-04-04 2023-05-31 Melexis Technologies NV Pulsed-light detection and ranging apparatus and method of detection and ranging of an object in a pulsed light detection and ranging system
US12004794B2 (en) * 2019-12-06 2024-06-11 Medtronic Cryocath Lp Active pressure control and method of fault monitoring
JP7397754B2 (ja) * 2020-05-14 2023-12-13 株式会社エー・アンド・デイ 自動血圧測定装置
WO2022059653A1 (ja) * 2020-09-15 2022-03-24 テルモ株式会社 動脈圧推定装置、動脈圧推定システム、及び動脈圧推定方法
JP7699344B2 (ja) * 2020-10-14 2025-06-27 株式会社エー・アンド・デイ 血圧監視装置
US20250255497A1 (en) * 2022-04-13 2025-08-14 Shenzhen Raycome Health Technology Co., Ltd. Method and device for non-invasive detection of central arterial pressure and other intraluminal large arterial pressures
CN114983362B (zh) * 2022-04-13 2025-07-22 深圳瑞光康泰科技有限公司 三通道脉搏波信号传感绑带以及脉搏波无创血压测量装置
JP2023157366A (ja) * 2022-04-14 2023-10-26 株式会社エー・アンド・デイ 血圧測定装置

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JPS5269089A (en) 1975-12-05 1977-06-08 Sanko Shiyouji Kk Buff grinding material
JPS5822029A (ja) * 1981-07-31 1983-02-09 テルモ株式会社 周期測定装置
JPS61122840A (ja) * 1984-11-19 1986-06-10 株式会社エー・アンド・ディ カフ圧力制御装置
JP2001333888A (ja) * 2000-05-29 2001-12-04 Nippon Colin Co Ltd 血圧測定装置
JP2007044363A (ja) * 2005-08-11 2007-02-22 A & D Co Ltd 血圧脈波検査装置

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Publication number Priority date Publication date Assignee Title
JPS5269089A (en) 1975-12-05 1977-06-08 Sanko Shiyouji Kk Buff grinding material
JPS5822029A (ja) * 1981-07-31 1983-02-09 テルモ株式会社 周期測定装置
JPS61122840A (ja) * 1984-11-19 1986-06-10 株式会社エー・アンド・ディ カフ圧力制御装置
JP2001333888A (ja) * 2000-05-29 2001-12-04 Nippon Colin Co Ltd 血圧測定装置
JP2007044363A (ja) * 2005-08-11 2007-02-22 A & D Co Ltd 血圧脈波検査装置

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Title
See also references of EP2823758A4

Also Published As

Publication number Publication date
EP2823758B1 (en) 2022-04-13
JP2013183814A (ja) 2013-09-19
EP2823758A1 (en) 2015-01-14
US10292604B2 (en) 2019-05-21
CN104159503B (zh) 2016-05-04
US20150025399A1 (en) 2015-01-22
EP2823758A4 (en) 2015-09-16
CN104159503A (zh) 2014-11-19
JP6086647B2 (ja) 2017-03-01

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