WO2013067974A1 - 一种活组织结扎装置 - Google Patents
一种活组织结扎装置 Download PDFInfo
- Publication number
- WO2013067974A1 WO2013067974A1 PCT/CN2012/084467 CN2012084467W WO2013067974A1 WO 2013067974 A1 WO2013067974 A1 WO 2013067974A1 CN 2012084467 W CN2012084467 W CN 2012084467W WO 2013067974 A1 WO2013067974 A1 WO 2013067974A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- clip
- living tissue
- adapter
- hole
- distal end
- Prior art date
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/068—Surgical staplers, e.g. containing multiple staples or clamps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/122—Clamps or clips, e.g. for the umbilical cord
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/122—Clamps or clips, e.g. for the umbilical cord
- A61B17/1227—Spring clips
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/128—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord for applying or removing clamps or clips
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/128—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord for applying or removing clamps or clips
- A61B17/1285—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord for applying or removing clamps or clips for minimally invasive surgery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/28—Surgical forceps
- A61B17/29—Forceps for use in minimally invasive surgery
- A61B2017/2901—Details of shaft
- A61B2017/2905—Details of shaft flexible
Definitions
- the utility model relates to a living tissue ligation device, which is mainly used for the discipline of digestive diseases, gastric and colonoscopy interventional therapy, and the treatment of active bleeding under non-venous varices under the endoscope, belonging to the field of minimally invasive medical device technology.
- the endoscope was born. Over the past 50 years, it has experienced a period from disease diagnosis to disease treatment. It is very effective and reliable for the treatment of some diseases.
- the stomach and intestines of living organisms often cause bleeding due to various diseases or accidental injuries or damage after endoscopic treatment.
- active bleeding it is generally treated by means of drug spraying, high frequency electricity, laser, argon burning bleeding point method, hemostatic clip mechanical compression and hemostasis.
- the mechanical compression of hemostasis to stop bleeding is reliable for the treatment of active bleeding caused by non-varicose veins, and has been approved by doctors and patients.
- the use of mechanical compression of the clip can also close the mucosal damage of the digestive tract to promote its wound healing; it can also close the small perforation of the digestive tract to avoid open surgery.
- the first type is a separate hemostatic clip for the clip and device.
- the clip is for one-time use and cannot be repositioned; the device is reusable. Every time a clip is released, the doctor needs to assemble new clips and devices on site, which is cumbersome to operate.
- the direction of the opening and closing operation of the clip is to pull the sliding handle to the proximal end. It is not easy to control, so that the clip can be closed before use, and the clip cannot be opened once it is closed. If the release position is wrong, other instruments need to be replaced. Remove it, reassemble the clip and re-release it to the lesion.
- the length of the clip is about l (Tl2mm).
- the device needs to be disinfected before each operation. Repeated disinfection will increase the risk of surgical infection.
- the second type is that the clip is integrated with the device, but the opening and closing cannot be repeated.
- the direction in which the clip is opened and closed is to pull the sliding handle toward the proximal end, which is difficult to control and makes the clip unused. It is closed in advance, and once the clip is closed, it cannot be opened. If the release is wrong, other instruments need to be replaced to remove it. Then, the new hemostatic clip is re-applied and inserted into the endoscope to re-clamp the hemostatic clip.
- such a hemostatic clip does not require a clip to be assembled, and the operation is simpler than the first one. After the clip is released, the length is approximately
- the third type is a re-openable clip, the clip and the device are pre-assembled into one; the repositionable position is more advanced than the first two, but due to the complicated structure, the sliding handle is pushed when opened, and the sliding handle is opened and closed when closed.
- the opposite direction is not easy to operate by mistake.
- the clip After release, the clip has a length of about 15.5mm and a thorn-like protrusion at the tail. It is not suitable for release into a narrow space such as the esophagus, and there is a risk of causing perforation of the digestive tract.
- the present invention provides a disposable biopsy ligation device in which the clip is integral with the device, the clip is positionable, and the clip length is short after release (about 12 13 mm in length).
- a living tissue ligating device comprising a clip, an operating device and a conveying device; the clip comprising a resilient clip and a tightening tube for receiving the elastic clip; the operating device comprising a handle and capable of sliding on the handle Slider
- the conveying device comprises an outer connecting mechanism and an inner connecting mechanism
- the outer connecting mechanism includes a spring tube, a connecting end, and a connecting pin; a proximal end fixedly coupled to the handle; a distal end of the spring tube is fixedly coupled to the connecting end; a distal end of the connecting end is adjacent to the tightening tube by the connecting pin
- An axial sleeve, the connecting portion of the connecting pin can be detached from the corresponding hole slot under a certain pulling force, so that the connecting end is detached from the tightening tube;
- the inner connecting mechanism is inserted into the outer connecting mechanism, and the inner connecting mechanism comprises a mandrel, a connecting member and an adapter; the proximal end of the mandrel is connected to the sliding portion of the operating portion through a conduit a block that can be pulled by the slider; a distal end of the mandrel a proximal end of the connecting member; a distal end of the connecting member is connected to a proximal end of the sexual clip through the adapter, and a distal end of the connecting member can be broken under a certain pulling force Getting off the proximal end of the elastic clip;
- the connecting member can act on a corresponding portion of the connecting pin to apply a corresponding pulling force, so that the connecting portion of the connecting pin is detached from the corresponding hole or slot
- the connecting pin comprises at least one traction portion extending to the bottom end of the extension arm, the top of the extension arm forming a wing portion and the axially tightening tube and the connecting end
- Corresponding ⁇ L or slot is adapted to hook into the hole or slot with a table to connect the tightening tube to the connecting end
- the segments can be broken under force and detached from the respective holes or slots.
- the connecting pin is integrally bent, forming two extending arms and a traction portion between the two extending arms; at least one of the extending arms is provided with the corresponding hole or slot With wings.
- the connecting pin is formed by bending a body
- An extension arm and a traction portion at the bottom of the extension arm are provided with wings adapted to the respective holes or slots.
- the connecting member comprises a detail portion and a notch portion at the distal end of the connecting portion, and the proximal end of the thin portion is connected to the distal end of the mandrel.
- a free end portion of the portion forming a hook shape, the hook shape forming a hole adapted to the adapter, and a bottom of the elastic clip is provided with a second connection hole adapted to the adapter,
- the adapter passes through the first a connecting hole and the second connecting hole, thereby connecting the clip to the connecting member; the hook shape can be broken away from the elastic clip under a certain pulling force.
- the notch portion includes two divided notch portions juxtaposed, and the free end portions of each of the divided notch portions are formed in a hook shape to form a first connecting hole adapted to the adapter.
- the proximal end of the thin portion has a thickness larger than the diameter of the mandrel, so that a receiving portion is formed at a connecting portion of the thin portion and the mandrel, and when the mandrel is pulled down with a certain pulling force, The receiving portion can abut the traction portion of the connecting pin to cause the wing portion of the connecting pin to fall out of the corresponding hole or slot.
- the distal end of the connecting member is provided with a dividing groove having a certain depth along the end surface diameter, and the bottom of the dividing groove is provided with a matching groove adapted to the adapter, so that the transfer The piece can be restricted in the fitting groove through the dividing groove into the fitting groove; the connecting member is made of an elastic material.
- the proximal end of the connecting member is a cylindrical cylinder, and a through groove extending through the tubular wall is disposed in an axial direction of the central portion of the cylindrical cylinder, and an extension arm of the connecting pin passes through the through slot.
- a pulling portion of the connecting pin is placed in the through groove; a distal end surface of the through groove forms a receiving portion, and the receiving portion acts on the pulling portion when the mandrel is pulled with a certain pulling force
- the wings of the connecting pin are detached from the respective holes or slots.
- the proximal end of the elastic clip is a thin arm portion, and the distal end connected to the thin arm portion is an exposed portion; the exposed portion is thicker than the thin arm portion, thereby forming a joint between the two
- the stopping portion enables the stopping portion to bear against the distal end portion of the tightening tube after the elastic clip is received to a certain position.
- the proximal end portion of the elastic clip of the clip is provided with a side lug; the inner wall of the tightening tube is provided with a hanging hole, and the side convex is separated after the elastic clip is separated from the connecting member The ear can be hung in the hooking hole to prevent the clip from coming off the tightening tube.
- the folded portion of the elastic clip of the clip forms a circular arc-shaped bottom
- the distal end portion of the connecting member forms a circular arc-shaped concave portion corresponding to the circular arc-shaped bottom
- the circular arc-shaped bottom can Accommodated in the circular arc-shaped recess
- the adapter is hooped in the circular arc-shaped recess
- the connecting member is made of an elastic material, and the circular arc-shaped recess can be deformed and broken by a certain tensile force to be detached from the folded portion and the adapter.
- the distal end of the tightening tube is provided with a barrier for separating the elastic clip and blocking the elastic clip from coming off.
- the adapter is a pin.
- the adapter is made of a metallic material or a non-metallic material having a high strength to prevent deformation deformation when subjected to a predetermined tensile force that breaks the connector.
- the live ligation device mainly comprises a clip and a flexible elongate delivery device.
- the clip is pre-assembled at the front end of the delivery device, and the clip of the clip can be pushed and pulled by the mandrel to control its opening, closing and release separation. Both the collet and the delivery device are disposable. There is no need to sterilize to avoid the risk of cross-infection.
- the clip can be repeatedly positioned. After the clip holds the tissue, the doctor decides whether to release the effect from the endoscope by observing whether the lesion state reaches the desired effect.
- the sliding handle can be slowly pushed to slowly open the clip, and then the tissue in the digestive tract is re-clamped until it is considered to be clamped to a more suitable tissue position by continuing to pull.
- the movable handle knows that the sliding handle can no longer be pulled, and at the same time, a "click" is heard, and the separated structure of the clip and the conveying device is broken due to reaching the predetermined pulling force, so that the clip is separated from the conveying device, and the clip is released and stayed in the clip. Effective hemostasis or closure of the lesion in the digestive tract of the organism.
- the invention adopts the above technical solution, and can provide a doctor with a simple and easy to use living tissue ligation device which can be widely used for various parts of the digestive tract, thereby effectively saving the operation time and maximally reducing the operation time. risk.
- FIG. 1 is a schematic view showing the assembly of a living tissue ligating device according to an embodiment of the present invention, wherein the elastic clip of the clip ligates the living tissue.
- Fig. 2 is a schematic view showing the assembly of the living tissue ligating device according to an embodiment of the present invention, wherein the elastic clip of the clip is in an open state.
- Figure 2a is a partial enlarged view of a portion A of Figure 2.
- 3 is a cross-sectional view showing a tightening tube of an outer connecting mechanism connecting clip in a living tissue ligating device according to an embodiment of the present invention.
- Fig. 4 is a cross-sectional view showing the tightening tube of the internal connecting mechanism connecting the clips in the living tissue ligating device according to an embodiment of the present invention.
- Figure 4a is an A-A view of the structure shown in Figure 4.
- Fig. 5 is a cross-sectional view showing the structure of Fig. 3 assembled with the structure shown in Fig. 4, wherein the elastic clip is in an open state.
- Fig. 6 is a cross-sectional view showing the structure of Fig. 3 assembled with the structure shown in Fig. 4, wherein the elastic clip is in a tightened state.
- Figure 6a is a C-C view of the structure shown in Figure 6.
- Fig. 7 is a schematic view showing the preparation of a tissue of a living tissue ligating device according to an embodiment of the present invention, in which a clip and a conveying device are shown.
- Fig. 8 is a schematic view showing a structure in which a living tissue ligation device ligations tissue according to an embodiment of the present invention, in which a clip and a conveying device are shown.
- Fig. 9 is a schematic view showing the completion of ligating tissue of a living tissue ligating device according to an embodiment of the present invention, in which a clip and a conveying device are shown, and the clip and the conveying device are separated.
- Fig. 10 is a view showing the connection of a mandrel to a connecting member in a living tissue ligating device according to an embodiment of the present invention.
- Figure 11 is a schematic illustration of a preferred connecting pin in a living tissue ligating device in accordance with one embodiment of the present invention.
- Figure 11a is a B-B view of Figure 11.
- Figure l ib is a schematic illustration of various other alternative cross-sections of the connecting pins of the living tissue ligation device of the present invention.
- Figure 12 is a schematic illustration of a preferred tightening tube in a living tissue ligating device in accordance with one embodiment of the present invention.
- Figure 12a is a cross-sectional view of the tightening tube of Figure 12.
- Figure 13 is a schematic illustration of a preferred connection tip in a living tissue ligating device in accordance with one embodiment of the present invention.
- Figure 14 is a schematic illustration of a preferred clip in a living tissue ligating device in accordance with one embodiment of the present invention.
- Figure 15 is a schematic illustration of a preferred adapter in a living tissue ligating device in accordance with one embodiment of the present invention.
- 16a, 16b, 16c are respectively several preferred embodiments of the mandrel of the living tissue ligating device of the present invention Schematic diagram.
- 17a, 17b, 17c. 17d, 17e are schematic views of a preferred embodiment of the integral structure of the connecting pin of the living tissue ligating device of the present invention.
- 18a, 18b, and 18c are schematic views of a preferred embodiment of a combined structure of the connecting pins of the living tissue ligation device of the present invention.
- Figure 19a is a schematic illustration of a tightening tube of one embodiment of a living tissue ligating device of the present invention showing a barrier arm.
- Fig. 19b is a schematic view showing the bending of the blocking arm in the tightening tube shown in Fig. 19a.
- Fig. 19c is a schematic view showing the clip in the tightening tube of Fig. 19a.
- Fig. 20a is a schematic view showing another embodiment of the tightening tube of the living tissue ligating device of the present invention, the main change being the blocking member.
- Fig. 20b shows the clip, the connecting end and the spring tube of still another embodiment, the main change being the blocking member.
- Figure 20c shows a barrier of yet another embodiment.
- Fig. 20d shows a state of use of the blocking member of Fig. 20c.
- Figures 21a and 21b show two other embodiments of the connector of the living tissue ligating device of the present invention.
- Figure 22a is a schematic illustration of still another embodiment of a connector for a living tissue ligating device of the present invention.
- Figure 22b is a B-B view of Figure 22a.
- Figure 22c is an eight view of Figure 22&.
- Figure 22d is a perspective view of the connector of Figure 22a.
- Fig. 22e is a view showing the state of use of the connecting member shown in Fig. 22a, showing the clip, the connecting member, the connecting pin, the connecting end, the spring tube, the mandrel and the like.
- Figure 23 shows still another embodiment of the living tissue ligating device of the present invention.
- Figure 24 is a schematic illustration of the living tissue ligating device of the embodiment of Figure 23 with the clip in a tightened condition.
- Figure 25 is a schematic illustration of another embodiment of a connector for a living tissue ligating device of the present invention. detailed description
- Fig. 1 through Fig. 15 and Fig. 16 show a living tissue ligating device and a component thereof in a preferred embodiment of the present invention.
- the living tissue ligating device includes a clip 10, an operating device 20, and a transport device 30.
- the clip 10 includes a resilient clip 11 and a tightening tube 12 in which the elastic clip is received.
- the operating device 20 includes a handle 21 and a slider 22 that can slide over the handle.
- the conveying device 30 includes an outer connecting mechanism 31 and an inner connecting mechanism 32.
- the outer connecting mechanism 31 includes a spring tube 311, a connecting end 312, and a connecting pin 313.
- the proximal end of the spring tube 311 is fixedly coupled to the handle 21; the distal end of the spring tube 311 is fixedly coupled to the proximal end of the connecting end 312.
- the distal end of the connecting end 312 is axially nested with the proximal end of the tightening tube 12 via a connecting pin 313.
- the joint of the connecting pin 313 can be detached from the corresponding hole or groove by a certain pulling force, so that the connecting end 312 is disengaged from the tightening tube 12.
- the pulling force here can be applied by the connecting member 322 described below.
- the inner connecting mechanism 32 includes a mandrel 321, a connecting member 322, an adapter 323, and penetrates through the outer connecting mechanism 21.
- the proximal end 3211 of the mandrel 321 is coupled to the slider 22 of the operating device 20 via a conduit 23 and can be pulled by the slider 22.
- the distal end 3212 of the mandrel 321 is coupled to the proximal end 3221 of the connector 322; the distal end 3222 of the connector 322 is coupled to the proximal end 111 of the resilient clip 11 by an adapter 323, and the distal end 3222 of the connector 322 can It is broken by a certain pulling force, so that it is disengaged from the proximal end 111 of the elastic clip 11.
- the above-described living tissue ligating device is mainly constructed in two parts, a clip 10 and a flexible and elongated conveying device 30.
- the clip 10 is pre-assembled at the front end of the transport device 30, and the assembly relationship is broken when subjected to a predetermined pulling force, thereby separating the clip 10 from the transport device 30 to release the clip 10, before the tension is reached for the predetermined breaking force.
- the clip 11 of 10 can be pushed or pulled by the mandrel 321 (sliding by the slider 22 of the external operating device) to control the clip 11 to be opened and closed a plurality of times, so that the clip 10 has a repositionable function.
- the sliding handle 21 can be pulled first to slowly close the clip 11 when clamping the tissue. This step is "pre-clamping". Then, the doctor can determine whether the clip can be released by observing the state of the lesion through the endoscope to see if the expected gripping effect is achieved. 10. If it is considered that the clamping position is not suitable, the clip 11 can be slowly opened by slowly pushing the sliding handle 21, and then the tissue in the digestive tract, for example, is re-clamped until it is considered to be clamped to a more suitable tissue position by continuing.
- the clip 10 firmly holds the digestive tract tissue of the living organism and stays in the digestive tract of the organism to effectively stop or seal the lesion.
- the living tissue to which the device can be applied is not limited to the digestive tract tissue.
- the outer connecting mechanism 31 includes a spring tube 311, a connecting end 312, and a connecting pin 313.
- the spring tube 311 and the chamfered end of the connecting end 312 are fixedly connected by welding or the like, that is, the proximal end of the connecting end 312 is connected to the distal end of the spring tube 311.
- the spring tube 311 is flexible with a tightly wound spring wire, which can withstand a large pressure and a certain tensile force.
- the connecting pin 313 includes two extension arms 3131, 3132 and a traction portion 3133 connected to the bottom end of the extension arm.
- the tops of the two extension arms 3131, 3132 form wing portions 31310, 31320 which are adapted to the side holes 3121 of the respective connection ends 312 and the side holes 123 of the tightening tube 12 and can be inserted into the holes in.
- the wings 31310, 31320 can be broken and deformed from the above two holes when subjected to a certain pulling force, so that the connecting end 312 and the tightening tube 12 are no longer connected.
- the traction portion 3133 is a receiving point for receiving the above-described pulling force, and the receiving portion 3224 of the connecting member 322 described hereinafter can withstand the pulling portion 3133 and has a tendency to move toward the proximal end, thereby enabling the above-described wing dropping procedure.
- the cross section of the extension arm is as shown in Fig. 11a.
- the extension arms of various cross-sectional shapes as shown in Fig. 1b can be used.
- the connecting end 312 includes a sleeve receiving hole 3122 for receiving the tight tube 12, and a side hole 3121 for hooking the connecting portion of the connecting pin 313.
- the sleeve portion 125 of the take-up tube 12 is provided with a side hole 123 into which the wing portion of the joint pin 313 is inserted from the inside to the side hole 123, that is, the joint pin 313 is fitted to the take-up tube 12.
- the socket position of the connecting end 312 is also provided with a corresponding side hole 3121, and the thin sleeve portion 125 of the tightening tube 12 equipped with the connecting pin 313 is inserted into the socket hole 3122 of the connecting end 312, The wings of the connecting pin 313 are pressed down to retract them. Then, the tightening tube 12 is rotated to align the side hole 3121 of the connecting end 312 with the side hole 123 of the tightening tube 12, and the pressed wing portion is ejected and simultaneously inserted into the side hole 3121 of the connecting end 312.
- the abutting surface 1250 of the tightening tube 12 is in contact with the distal end surface 3124 of the connecting end 312 (formed with the spacing step 3125), and the tightening tube 12 and the connecting end 312 are axially connected to the wing of the connecting pin 313. Socketed together.
- Other components of the connector tip 312 are shown as 13, wherein reference numeral 3126 is a spring tube attachment aperture.
- the sum of L4 0.3 mm prevents the wings from protruding and is not conducive to the operation of the doctor; but not less than 0.25 mm, preventing the escape of the connecting pin 313 causes the clip 10 to be separated from the conveying device 30.
- the connecting end 312 and the tightening tube 12 are impossible to separate; conversely, if the wing portion of the connecting pin 313 is from the side of the tightening tube 12 and the connecting end 312, respectively The inside of the hole is disengaged, and the tightening tube 12 and the connecting end 312 are in a free state in the axial direction, so that the connecting end 312 is separated from the tightening tube 12.
- the inner connecting mechanism mainly includes a core shaft 321, a connecting member 322, and an adapter 323.
- the proximal end 3221 of the connector 322 is fixedly coupled to the mandrel 321 .
- the adapter 323 connects the distal end 3222 of the connector 322 with the proximal end (bottom end) of the clip 11, the specific structure and manner of which will be described below.
- the connector 322 includes a detail 3221 and a notch 3222 that is coupled to the distal end of the detail 3221.
- proximal end of the detail 3221 and the distal end of the mandrel 321 are firmly connected by laser welding, high frequency splicing or hinge or other connection, and can withstand a predetermined separation force without being damaged.
- the inner diameter of the spring tube 311 is 1. 2 ⁇
- the inner diameter of the spring tube 311 is about 1. 1 ⁇
- the inner diameter of the spring tube 311 is 1. 2 ⁇
- the large diameter portion of the inner hole of the spring tube 311 is occupied, so that the receiving portion 3224 is formed at the joint portion between the thin portion and the mandrel.
- the receiving portion 3224 can abut the pulling portion 3133 of the connecting pin 313.
- the wings of the connecting pin are detached from the corresponding holes or slots.
- the main shaft 321 may be a single-stranded wire or a multi-stranded metal wire rope (as shown in Fig. 16a), and the preferred embodiment is as shown in Fig. 16c, which is a single-strand steel wire (0.22 ⁇ . 1 ⁇ ).
- a thinner steel wire such as a 0.3 mm steel wire or a front end of the thick steel wire to be 0.3 to 3 (as shown in Fig. 16b, Fig. 8 to Fig. 10, forming a thin end portion 3210), which is advantageous for flexibility of movement.
- the shank member can be flexibly moved in the axial direction, and has a width of about 1. 1 ⁇ , a thickness of 0. 2 ⁇ 0. 3mm, the shape of the shank can be various shapes, but is limited to a diameter of 1. 2. Within 2mm of the circular area, this can be flexibly moved inside the spring tube 311 without forming too much clearance with the inner hole of the spring tube 311.
- the size of the detail may be changed according to actual needs, as long as the flexible movement is performed without causing too much clearance with the inner hole.
- the free end portion of the notch portion 3222 is formed in a hook shape, and the hook forms a first connecting hole 3223 adapted to the adapter.
- the elastic clip 11 has a two-piece assembly structure, and the bottom (proximal end) of the elastic clip 11 is provided with a second connecting hole 117 adapted to the adapter 323.
- the adapter 323 passes through the first connection hole and the 3223 second connection hole 117, thereby connecting the elastic clip 11 to the connector 322.
- the hook of the notch is deformed or broken when subjected to a predetermined tensile force.
- the notch portion 3222 includes two sub-notch portions 32221, 32222 which are juxtaposed, and the free end portions of each of the notch portions are formed in a hook shape to form an adapter portion 323.
- the hooks of the two divided notches 32221, 32222 are hooked in opposite directions.
- the proximal ends of the two notched portions of the connecting member are first welded to the front welding hole 301 (as shown in FIG.
- the proximal end of the notched portion is not provided with a connecting hole, and laser welding or electric resistance welding is also used.
- the front weld hole is welded to the notch portion, and the two notch portions of the distal end of the connecting member are integrally formed into a parallel mode. Then, the two divided notches 32221, 32222 are appropriately separated, and then two elastic clips are used.
- the proximal spring opening lug 1 16 can be re-opened in the hanging hole 122 of the tightening tube 12 in advance. Then the two connecting holes 117 of the two clips 11 are connected to the two connecting ends. The first connecting hole 3223 of the piece 322 is aligned, The four adapter 323 is inserted into the hole, the connecting member 322 and clip 11 are connected together, so that the mandrel 321 through the connector 322 to the clip 11 are connected together.
- the adapter 323 is a pin.
- the adapter 323 can also be tubular or any other shape that can be coupled to the connector and to the clip in the prior art.
- the material of the adapter 323 may be a metal material or a non-metallic material with high strength so as to be able to withstand a predetermined tensile force without breaking deformation, that is, when the notch portion 3222 of the connecting member 322 is broken, the adapter 323 is not Will be destroyed and deformed.
- the clip 10 includes a clip 11 and a tightening tube 12 that receives the clip 11 therein.
- the clip 11 is made of an elastic material, and a usable material such as SUS301, SUS63U SUS304 or the like, or a cross-sectional shape of a sheet or strip having a certain hardness and strength and high elasticity such as a high-performance polymer material such as PEEK can be used.
- a usable material such as SUS301, SUS63U SUS304 or the like, or a cross-sectional shape of a sheet or strip having a certain hardness and strength and high elasticity
- a high-performance polymer material such as PEEK
- the cross-section is a circle having a diameter of 0. 2mm.
- the elastic clip is bent into a curved shape as shown in FIG. 14, the proximal end 111 is a thin arm portion, and the distal end connected to the thin arm portion is an exposed portion 112; the exposed portion 112 is thicker than the thin arm portion. 111, thereby forming a stop portion 113 at the junction of the two, so that the retaining portion 113 can withstand the tightening tube after the clip 11 is received to a certain position
- the fold is a rounded portion 115.
- the second connection hole 114 described above is provided at the proximal end of the thin arm portion 111.
- the thin arm portion 111 forms a small bent portion 1111 and a large bent portion 1112.
- the proximal end portion of the elastic clip 11 of the clip 10 is provided with a side lug 116.
- the inner wall of the tightening tube 12 is provided with a hanging hole 122. After the elastic clip 1 1 and the connecting member 322 are separated, the side lug 1 16 can be It is hung in the hanging hole 122 to prevent the clip 11 from coming off the tightening tube 12.
- the tightening tube 12 is provided at the distal end portion with a closing hole 124 for collecting the clip 1 1 , and at the distal end portion is further provided with a blocking member 12 1 traversing the collecting hole, and the number of the blocking piece and the number of the clamping piece are always Separate the clips one by one; at the same time prevent the clips from coming off the aperture of the collapsing hole.
- the inner connecting mechanism 32 and the clip 11 are inserted from the distal end of the outer connecting mechanism 31 (the proximal end is connected with the tightening tube 12), and then the blocking member 121 is inserted into the blocking hole 1210 of the tightening tube 12 to prevent the inner connecting mechanism. It is detached from the distal end with the outer connecting mechanism 31.
- the slider is pushed, that is, the pusher shaft 321 is pushed, the clip 11 will move toward the distal end of the tightening tube 12, and the large bent portion forced by the tightening tube 12 will return to the original curved state, so that two pieces are made.
- the exposed portions of the clips 1 1 are separated from each other to open the clips 10 until the bottoms of the mutually separated clips 11 are unable to continue to be pushed after reaching the blocking member 121, and the opening process of the clips 10 is completed.
- the distance L1 between the pulling portion of the connecting pin 313 and the tensile portion of the connecting member 322 reaches the maximum state, and the distance between the hooking hole 122 of the tightening tube 12 and the side lug 116 of the clip 11 is also maximized.
- the side holes of the tightening tube 12 and the connecting end 312 are both slightly larger than the wings of the connecting member 322, which facilitates assembly. Due to the thrust of the mandrel 321 , the tightening tube 12 is also moved toward the distal end thereof. At this time, the side holes of the tightening tube 12 and the connecting end 312 are no longer overlapped, and the wings of the connecting pin 313 are engaged in the staggered state. The staggered position prevents the tightening tube 12 from being separated from the connecting end 312 by the driving of the clip 11.
- the clip 10 can be slowly approached to the bleeding point or the perforation position of the condition by the endoscope observation, and the movement of the endoscope or the doctor pushes the endoscope or rotates by adjusting the endoscope knob.
- the endoscope causes the clip 10 to be as far as possible from the bleeding point at an angle of 60 to 90 degrees and to press down on the tissue surrounding the condition.
- the slider 22 is slowly pulled to drive the mandrel 321, the connecting member 322, the adapter 323, and the clip 11 to move proximally together.
- the distance between the pulling portion of the connecting pin 313 and the tensile portion of the connecting member 322 is L1 gradually becomes smaller and L2 gradually shrinks.
- the clip 11 is pulled back into the tightening tube 12, and the clip 11 which has just been bent is gradually pressed by the mouth of the tightening tube 12 and close to each other until the stopper 113 of the clip 11 is
- the stopping surface of the tightening tube 12 is in contact, the direction of the L2 is changed, and the side lugs of the clip 11 exceed the distal end edge of the mounting hole of the tightening tube 12, at which time the two clips 11 have Close to each other and completed the clamping of the tissue surrounding the disease.
- the pulling force is far from the predetermined release pulling force, and the internal and external connecting mechanisms are not damaged, which also ensures that the clip 10 can be opened and closed multiple times.
- the sliding handle 21 can be pushed, and the clip 11 is moved by the mandrel 321 to the distal end of the tightening tube 12, and the clip 11 is opened again.
- the physician can again pre-clamp the clip 10 to the location of the condition for a second time until such time as the physician confirms the position of the gripping tissue through the endoscope to the optimal location for treating the condition.
- the sliding handle 21 is continuously pulled until the stopping portion 113 of the clip 11 comes into contact with the stopping surface of the tightening tube 12, and the clip 11 can no longer move to the proximal end of the tightening tube 12; at this time, the tube 12 is tightened.
- the abutting surface abuts against the end surface of the connecting end 312 to receive the pulling force from the slider 22.
- the mandrel 321 drives the connecting member 322 to continue to move proximally.
- the sliding handle 21 is continuously pulled.
- the connecting pin 313 will be driven to move toward the proximal end.
- the wing portion 31310 of the originally squeezed connecting pin 313 is in the radial direction
- the upper portion is in a free state, and the wing portion of the connecting pin 313 is pulled out from the side hole of the connecting end 312 and the tightening tube 12, so that the connecting end 312 and the tightening tube 12 are freely in the axial direction, so that the connection is made.
- the tip 312 is separated from the take-up tube 12 to separate the clip 10 from the delivery device 30.
- the proximal end of the clip 11 bound by the connecting member 322 is elastically stretched apart from each other by a distance k2 and the side lug is caught in the hooking hole 122 of the tightening tube 12, so that the clip 11 cannot be easily pulled out.
- the clip 10 is released and retained in the digestive tract of the living organism, and effective ligation is performed on the diseased part.
- the connecting pin 313 in the above preferred embodiment can be replaced with the connecting pin 313 structure as shown in Figs. 17a - 18c.
- the connecting pins 313 shown in Figs. 17a to 17e are all unitary, that is, integrally bent. 17a-17c, two extension arms 3131, 3132 and a traction portion 3133 between the two extension arms are formed; the free ends of the at least one extension arms are provided with wings adapted to the respective holes or slots 31310, 31320. Or as shown in FIGS.
- the traction portions 3134, 3135 are formed; the traction portions 3134, 3135 are epitaxially formed in a spiral shape to bear against the tube wall of the spring tube; the wing portion 3130 is formed at the other end of the traction portion, or the extension arm 3136 is formed.
- the free end of the extension arm 3136 forms a wing portion 3360.
- the connecting pin 313 in the above preferred embodiment may also be replaced with the combined structure of Figs. 18a - 18c, which is similar to the above structure to form one or two extension arms, or to form three extension arms (one more extension arm 3137), Wings 31310, 31320, 31370 are formed at the free ends of each of the extension arms.
- Wings 31310, 31320, 31370 are formed at the free ends of each of the extension arms.
- the number of extension arms is 2 or more, only one of the extension arm setting wings may be selected.
- the blocking member 121 in the above preferred embodiment can be replaced with the blocking member structure as shown in Figs. 19a to 20d.
- the blocking member shown in Figs. 19a and 19b is a structure in which the two blocking arms 1211 on the take-up tube 12 are bent to form a function having a stopper, and Fig. 19c shows the state of use thereof.
- the blocking members shown in Fig. 20a are assembled structures, and the assembly can be connected to the tightening tube through a welding process such as welding riveting.
- Figure 20b shows a pin-like structure inserted into the blocking hole on the tightening tube 12 while tightening the tube
- a barrier structure is formed within 12.
- the blocking member is also an assembled structure, but the blocking member is a radially elastic original member whose maximum outer diameter D3 is slightly larger than the connecting aperture D2 of the tightening tube 12, and the chamfered front end diameter D4 of the blocking member is slightly smaller than D2.
- the chamfered end of the blocking member is placed in the connecting hole and then pressed down forcefully, and the radially elastic blocking member is narrowed inwardly into the blocking member hole 1210 until the blocking member passes from the tightening tube 12
- the other blocking member aperture 1210 is threaded out; at this point the blocking member is snapped into the blocking member aperture 1210 of the take-up tube 12 by virtue of its radial elasticity.
- the blocking member and the tightening tube 12 may also be subjected to a joining process such as laser welding to be more firmly fixed in the stopper hole 1210 of the tightening tube 12.
- the manner of splicing the tightening tube 12 and the connecting end 312 in the above preferred embodiment may be replaced by: the tightening tube 12 is provided with a socket hole, and the side hole is provided on the side wall; the connecting end 312 is provided with a sleeve The joint is provided with side holes on its side wall, and then sleeved together through the adapter through the two side holes.
- the connector 322 in the above preferred embodiment can be replaced with the structure shown in Figs. 21a and 21b.
- the connector 322 is assembled in two pieces, with the hooked hooks of the two divided notches being on the same side (Fig. 21b), or hooked to the different sides (Fig. 21a).
- the connecting member shown in Fig. 21a is different from the connecting member shown in Figs. 1 to 16 described above in that the two divided notches are integrally formed, and the front welding holes are not required to be joined.
- the second embodiment of the present invention is as shown in Figs. 22a to 22e, mainly in that the structure of the connecting member is changed.
- the proximal end of the connecting member 80 is a cylindrical cylinder, and a through groove 83 penetrating the cylindrical wall is provided in the axial direction of the central portion of the cylindrical cylinder, and the extending arm of the connecting pin 313 is worn through the through groove 83.
- the traction portion of the connecting pin 313 is located in the through groove 83.
- the distal end surface 831 of the through groove 83 forms a receiving portion, and the core shaft 321 is fixed to the rear hole 832 of the proximal end surface of the through groove 83 by welding or the like.
- the distal end of the connecting member 80 is provided with a dividing groove 81 having a certain depth along the end surface diameter.
- the bottom of the dividing groove 81 is provided with a matching groove 82 adapted to the adapter, and the connecting member is made of an elastic material;
- the connector can be restricted in the adapter slot 82 by the split slot 81 entering the adapter slot 82.
- the dividing groove 81 is opened to disengage the adapter from the center, thereby achieving separation of the connecting member from the clip.
- the connector in the above embodiment can also be replaced by the connector 90 shown in FIG. As shown in Fig. 25, its receiving portion serves as a pin 93 passing through the proximal cylindrical cylinder.
- the distal end portion also has a dividing groove 91 and an adapting groove 92.
- Other structures are similar to the above-mentioned connecting member 90, and are not described herein.
- the fitting groove 83 is provided with a recess adapted to the side lug 116 at a lower position, which can be used as a push-out clip. The support point, the opposite side lug 16 is forced.
- the third embodiment of the present invention is similar to the second embodiment described above, as shown in Figs. 23 and 24, except that the clip 40 is formed into a unitary form from the contiguous assembly form.
- the folded portion of the elastic clip forms a circular arc-shaped bottom 118
- the distal end portion of the connecting member forms a circular arc-shaped concave portion 3228 corresponding to the circular arc-shaped bottom 118.
- the connecting member is made of an elastic material, and the circular arc-shaped bottom 118 can be Accommodated in the arcuate recess 3228, the adapter 328 is hooped at the bottom of the arcuate recess 3228 to connect the clip to the connector.
- the connecting member When the sliding handle is pulled to move the clip to contact with the stopping surface of the tightening tube, the connecting member is pulled, and the circular arc-shaped recess 3228 of the connecting member is deformed and the connecting member is separated from the adapter. At this time, the folded portion of the clip is detached from the circular arc-shaped recess 3228 of the connecting member and comes into contact with the side wall of the tightening tube to generate a certain frictional force, and the maximum point is caught at the distal end of the inner boss, which prevents the clip from being engaged. Tighten the movement of the tube.
- the pulling portion of the connecting member abuts the receiving portion of the connecting pin, continues to pull the connecting member, the connecting member drives the connecting pin to move together to move proximally, and the wing of the connecting pin is removed from the tightening tube and The side holes of the connecting end are pulled out to separate the clip from the conveying device.
- Inner connecting mechanism 32 Grinding end 3210 Flattening end 3211 Mandrel 321 Detail 3221 Notch 3222 Connector 322 Part notch 32222 Partial notch 32221 Adapter 323 First connecting hole 3223 Front welding hole 301 Receiving part 3224 Rear welding hole 302 alternative connector one split slot one 81 through slot 83 far 80 fit slot one 82 end face 831
Landscapes
- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Medical Informatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Reproductive Health (AREA)
- Vascular Medicine (AREA)
- Surgical Instruments (AREA)
- Endoscopes (AREA)
Abstract
Description
Claims
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201280042482.6A CN103930051B (zh) | 2011-11-11 | 2012-11-12 | 一种活组织结扎装置 |
US14/234,642 US9510836B2 (en) | 2011-11-11 | 2012-11-12 | Living tissue ligation device |
EP12847860.9A EP2777548B1 (en) | 2011-11-11 | 2012-11-12 | Living tissue ligating device |
AU2012334534A AU2012334534A1 (en) | 2011-11-11 | 2012-11-12 | Living tissue ligating device |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201110358591.6 | 2011-11-11 | ||
CN201110358591 | 2011-11-11 |
Publications (1)
Publication Number | Publication Date |
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WO2013067974A1 true WO2013067974A1 (zh) | 2013-05-16 |
Family
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Application Number | Title | Priority Date | Filing Date |
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PCT/CN2011/002006 WO2013067662A1 (zh) | 2011-11-11 | 2011-11-30 | 一种夹持或结扎装置 |
PCT/CN2012/080793 WO2013067844A1 (zh) | 2011-11-11 | 2012-08-30 | 夹持结扎装置 |
PCT/CN2012/084467 WO2013067974A1 (zh) | 2011-11-11 | 2012-11-12 | 一种活组织结扎装置 |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/CN2011/002006 WO2013067662A1 (zh) | 2011-11-11 | 2011-11-30 | 一种夹持或结扎装置 |
PCT/CN2012/080793 WO2013067844A1 (zh) | 2011-11-11 | 2012-08-30 | 夹持结扎装置 |
Country Status (7)
Country | Link |
---|---|
US (2) | US9492176B2 (zh) |
EP (2) | EP2777549A4 (zh) |
KR (1) | KR101554443B1 (zh) |
CN (3) | CN103930052B (zh) |
AU (2) | AU2012334663C1 (zh) |
BR (1) | BR112014006488A2 (zh) |
WO (3) | WO2013067662A1 (zh) |
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KR20180098682A (ko) * | 2016-02-23 | 2018-09-04 | 스미또모 베이크라이트 가부시키가이샤 | 클립 카트리지 |
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DE112019005835T5 (de) * | 2019-01-03 | 2021-10-14 | Olympus Corporation | Klammervorrichtung für große Defekte, Perforationen und Fisteln |
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- 2012-11-12 CN CN201280042482.6A patent/CN103930051B/zh active Active
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KR101975732B1 (ko) | 2016-02-23 | 2019-05-07 | 스미또모 베이크라이트 가부시키가이샤 | 클립 카트리지 |
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AU2012334663B2 (en) | 2014-08-21 |
KR101554443B1 (ko) | 2015-09-18 |
US20140171973A1 (en) | 2014-06-19 |
CN103930051B (zh) | 2016-05-25 |
KR20140048304A (ko) | 2014-04-23 |
US20140171974A1 (en) | 2014-06-19 |
EP2777548A4 (en) | 2015-09-09 |
EP2777549A1 (en) | 2014-09-17 |
AU2012334663C1 (en) | 2014-11-20 |
AU2012334663A1 (en) | 2014-02-13 |
US9510836B2 (en) | 2016-12-06 |
WO2013067662A1 (zh) | 2013-05-16 |
WO2013067844A1 (zh) | 2013-05-16 |
CN103930052A (zh) | 2014-07-16 |
CN103930052B (zh) | 2016-02-10 |
CN202960641U (zh) | 2013-06-05 |
AU2012334534A1 (en) | 2014-02-13 |
BR112014006488A2 (pt) | 2017-04-25 |
EP2777548B1 (en) | 2017-04-05 |
EP2777549A4 (en) | 2015-09-09 |
US9492176B2 (en) | 2016-11-15 |
EP2777548A1 (en) | 2014-09-17 |
CN103930051A (zh) | 2014-07-16 |
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