WO2013015156A1 - アルキルジオールモノグリシジルエーテルの製造方法 - Google Patents
アルキルジオールモノグリシジルエーテルの製造方法 Download PDFInfo
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- WO2013015156A1 WO2013015156A1 PCT/JP2012/068115 JP2012068115W WO2013015156A1 WO 2013015156 A1 WO2013015156 A1 WO 2013015156A1 JP 2012068115 W JP2012068115 W JP 2012068115W WO 2013015156 A1 WO2013015156 A1 WO 2013015156A1
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D301/00—Preparation of oxiranes
- C07D301/27—Condensation of epihalohydrins or halohydrins with compounds containing active hydrogen atoms
- C07D301/28—Condensation of epihalohydrins or halohydrins with compounds containing active hydrogen atoms by reaction with hydroxyl radicals
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/24—Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds
- C07D303/26—Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds having one or more free hydroxyl radicals
Definitions
- the present invention relates to a method for producing alkyldiol monoglycidyl ether using vinyl ether-containing alcohol.
- Alkyldiol monoglycidyl ether is useful as an intermediate for pharmaceuticals, agricultural chemical raw materials and paints, and UV curable resins for electronic materials.
- a conventional method for producing an alkyldiol monoglycidyl ether a method in which an alkanediol and an epihalohydrin are reacted using an alkali hydroxide is generally known (see, for example, Patent Documents 1 to 3). These production methods are usually steps for removing epihalohydrin, water, and the like by removing salts generated as a by-product by washing with water after the reaction and heating to reflux.
- Patent Document 4 requires an equivalent amount of diol as the raw material to be used, and further, the removal of the acetal compound by-produced from the diol requires conditions of high temperature and near vacuum, which is inefficient. is there.
- the inventors' further investigation revealed the problem that a high-boiling acetal glycidyl ether dimer derived from a diol compound was produced.
- This invention makes it a subject to provide the manufacturing method which can manufacture alkyldiol monoglycidyl ether efficiently with high purity and a high yield, without requiring a complicated refinement
- a vinyl ether-containing alkyl glycidyl ether is obtained by glycidylation of a vinyl ether-containing alcohol, and then a intendylation method in which water is allowed to coexist in the presence of an acid catalyst to obtain an alkyl diol monoglycidyl ether.
- a acetal-type glycidyl ether dimer is produced as a by-product during the istylation reaction, but by adding an aqueous acid solution after the istylation reaction, the glycidyl ether dimer is decomposed to produce alkyl diol monoglycidyl. It was found that ether was obtained. That is, the present invention is as follows.
- R represents a linear or alicyclic alkylene group or a linear or alicyclic alkenylene group.
- the method for producing the alkyldiol monoglycidyl ether of the present invention comprises converting a vinyl ether-containing alcohol to a vinyl ether-containing alkyl glycidyl ether by glycidylation, then performing a istylation method in the presence of an acid catalyst and water, and then further adding an acid. It includes a step of performing an acetal decomposition reaction by adding an aqueous solution.
- the hydroxyl group of vinyl ether-containing alcohol is glycidylated to obtain vinyl ether-containing glycidyl ether.
- the glycidylation reaction method cannot be applied because the vinyl group reacts in the method using an acid catalyst, but it is generally used if it is a reaction with an epihalohydrin using an alkali metal hydroxide. The method is applicable.
- Examples of the vinyl ether-containing alcohol used in the present invention include 4-hydroxybutyl vinyl ether, 6-hydroxyhexyl vinyl ether, 9-hydroxynonyl vinyl ether, 10-hydroxydecanyl vinyl ether, 12-hydroxydodecyl vinyl ether, cyclohexanedimethanol monovinyl ether, Examples include compounds represented by the following general formula (I) such as cyclohexene dimethanol monovinyl ether.
- R represents a linear or alicyclic alkylene group or a linear or alicyclic alkenylene group.
- R in the general formula (I) represents a linear or alicyclic alkylene group or a linear or alicyclic alkenylene group, and the linear alkylene group preferably has 2 to 20 carbon atoms, The alicyclic alkylene group preferably has 2 to 20 carbon atoms.
- the linear alkenylene group preferably has 2 to 20 carbon atoms, and the alicyclic alkenylene group preferably has 2 to 20 carbon atoms.
- the alkali metal hydroxide used in the glycidylation reaction according to the present invention is not particularly limited, and examples thereof include potassium hydroxide and sodium hydroxide.
- the amount of them used is required to be 1 equivalent or more, preferably 1 to 2 equivalents relative to the vinyl ether-containing alcohol. When the amount is less than 1 equivalent, the reaction stops in the middle, and when it exceeds 2 equivalents, side reactions tend to occur, and the purity tends to decrease.
- the epihalohydrin used in the present invention is preferably epichlorohydrin because it is easily available. Further, the amount used is 1 equivalent or more, preferably 1 to 10 equivalents, relative to the vinyl ether-containing alcohol. When the amount is less than 1 equivalent, the reaction stops in the middle, and when the amount exceeds 10 equivalents, side reactions tend to occur and the purity tends to decrease.
- a catalyst such as a quaternary ammonium salt can be used.
- a quaternary ammonium salt to be used common ones such as benzyltrimethylammonium chloride, benzyltriethylammonium chloride, tetramethylammonium chloride, tetraethylammonium chloride can be used.
- distillation purification After obtaining vinyl ether-containing glycidyl ether by glycidylation reaction, further distillation purification may be performed.
- vacuum distillation is generally suitable, although it depends on the boiling point of the vinyl ether-containing glycidyl ether.
- the intendylation reaction according to the present invention is carried out in the presence of an acid catalyst in the presence of water.
- the acetaldehyde generated during the istylation reaction can be removed by reducing the pressure in the reaction system, but a part of the acetaldehyde is taken into water and reacted with the alkyldiol monoglycidyl ether generated by the devinylation reaction.
- alkyl diol monoglycidyl ether methyl acetal (acetal dimer).
- acetal dimer When the acetal dimer remains, when the substance obtained by the present invention is polymerized and used, problems such as high viscosity and gelation due to a crosslinking reaction occur.
- the acetal dimerization reaction is a reversible reaction and is easily decomposed under an acid catalyst
- the acetal dimer is decomposed by performing an acetal decomposition reaction described later. .
- the acid catalyst that can be used in the intendylation reaction according to the present invention usually, sulfuric acid, sodium hydrogen sulfate, paratoluenesulfonic acid, benzenesulfonic acid, methanesulfonic acid, solid acid (zeolite, amberlite, amberlist, Nafion etc.).
- the amount of the catalyst used is preferably 0.1 to 10% by mass with respect to the vinyl ether-containing glycidyl ether to be reacted, and more preferably 0.5 to 2% by mass from the viewpoint of reactivity.
- the amount of the catalyst used is less than 0.1% by mass, the devinylation reactivity is remarkably lowered and the reaction becomes extremely slow.
- more than 10 mass% many by-products including acetal dimer and the ring-opening and superposition
- the amount of water used in the intendylation reaction according to the present invention is not particularly limited as long as it is equimolar or more with respect to the vinyl ether-containing glycidyl ether, but preferably 20 to 60 with respect to the vinyl ether-containing glycidyl ether.
- the intendylation reaction proceeds promptly and the amount of acetal dimer produced can be suppressed.
- the amount of water used is less than 20% by mass relative to the vinyl ether-containing glycidyl ether, the amount of by-products such as acetal dimer, ring opening of the glycidyl group and polymerized polymer exceeds 60% by mass.
- the intendylation reaction becomes slow. Furthermore, if the amount is less than equimolar, the progress of the devinylation reaction stops midway.
- the devinylation reaction according to the present invention is an exothermic reaction, and acetaldehyde generated by the reaction needs to be removed by reducing the pressure in the system.
- the reaction temperature By controlling the reaction temperature at 60 ° C. or lower, preferably 20 ° C. to 50 ° C., it becomes possible to obtain a high-purity alkyldiol monoglycidyl ether with suppressed gelation and by-products.
- Examples of the method for controlling the reaction temperature include cooling the reactor or gradually adding vinyl ether-containing glycidyl ether to the catalyst aqueous solution. In addition, after the end of heat generation, warm in a warm bath to maintain the temperature. When the reaction temperature is in the range of 20 ° C.
- acetaldehyde can be removed from the reaction system by setting the pressure in the system to 50 kPa or less.
- the pressure in the system is more preferably 30 kPa or less.
- the present invention is characterized in that after the istylation reaction is performed, an aqueous acid solution is further added to perform an acetal decomposition reaction.
- the acid aqueous solution the acid aqueous solution exemplified in the above description of the acid catalyst can be used.
- the amount of the acid aqueous solution added is not particularly limited, but is preferably 0.1 to 10% by mass based on vinyl ether-containing glycidyl ether.
- the concentration of the acid aqueous solution is not particularly limited, but is preferably 0.01% by mass to 5% by mass. If the amount and concentration of acid in the acetal decomposition reaction is out of these ranges, the decomposition reaction may be significantly slowed or by-products may be formed.
- the pressure in the reaction system at the time of acetal decomposition can be continuously carried out under the conditions of the istylation reaction, but in order to make the reaction proceed rapidly, the pressure in the system is preferably 20 kPa or less, More preferably, it is 10 kPa or less.
- a base examples include hydroxides or salts of alkali metals and alkaline earth metals such as potassium hydroxide, sodium hydroxide, potassium carbonate, sodium carbonate, potassium bicarbonate, and sodium bicarbonate.
- a solvent such as toluene or xylene can be used alone or in combination of two or more in order to increase the separation ability.
- a method of increasing the specific gravity can be used.
- the solvent is distilled off by concentration if excess water or solvent is used. Concentration is preferably carried out at normal pressure or reduced pressure while maintaining the liquid temperature at 90 ° C. or lower, more preferably in the range of 65 ° C. to 85 ° C. When the liquid temperature exceeds 90 ° C., there is a high possibility that the alkyldiol monoglycidyl ether is colored or decomposed.
- insolubles such as remaining neutralized salts can be removed by filtration.
- a filter aid such as diatomaceous earth.
- the alkyldiol monoglycidyl ether production method of the present invention can obtain alkyldiol monoglycidyl ether by performing istylation reaction and acetal decomposition reaction by using water, purification steps other than filtration are Although not necessary, a general purification method such as distillation can be carried out depending on the case.
- Example 2 After synthesizing vinyloxybutyl glycidyl ether, vacuum distillation was performed, and the same operation as in Example 1 was performed except that this was used for the synthesis of butanediol monoglycidyl ether. The vacuum distillation was performed at a pressure of 0.4 kPa, and the distillation temperature was 82 ° C. The obtained purified vinyloxybutyl glycidyl ether had a purity of 99% and a yield of 94%. Further, butanediol monoglycidyl ether finally obtained by devinylation and acetal decomposition was obtained with a purity of 95% and a yield of 99%. At this time, butanediol contained in the obtained substance was 0.1%, and no acetal dimer was detected.
- the butanediol in the butanediol monoglycidyl ether obtained by the methods of Examples 1 and 2 was 0.2% or less, and butanediol diglycidyl ether was not detected.
- the reaction solution was extracted 5 times with 600 g of water and 300 g of ethyl acetate, and the organic layer was washed twice with 200 g of water.
- the organic layer was concentrated with a rotary evaporator to distill off ethyl acetate, followed by filtration to obtain the desired butanediol monoglycidyl ether in a purity of 87% and a yield of 41%.
- the butanediol contained in the obtained substance was 4%
- the diglycidyl ether was 5%
- a plurality of unknown components were detected by gas chromatography.
- reaction conversion rate was 23% after 3 hours of reaction, 0.3 g of paratoluenesulfonic acid was added and the reaction was performed, and the reaction conversion rate became 100% 1 hour after the addition.
- the mixture was further stirred for 4 hours until the produced ethylene glycol methyl acetal was not detected on gas chromatography, and then 0.5 g of magnesium oxide was added to neutralize the solution, followed by filtration.
- the desired butanediol monoglycidyl ether was obtained with a purity of 88% and a yield of 94%. At this time, 5.5% of a peak considered to be a reaction product of butanediol monoglycidyl ether and ethylene glycol methyl acetal was detected in the obtained substance by analysis by liquid chromatography.
- Comparative Example 2 an excessive amount of ethylene glycol is used, and a reaction product with by-produced ethylene glycol methyl acetal is generated, resulting in a decrease in purity.
- Example 3 differs from Example 1 only in that it did not undergo an acetal decomposition reaction. Naturally, the acetal dimer remains, and the purity of the synthesized butanediol monoglycidyl ether is higher than that of Examples 1 and 2. Was also inferior.
- Comparative Examples 4 to 5 are examples in which acid or water was used alone in the acetal decomposition reaction, and no decomposition occurred, and it can be seen that addition of an acid aqueous solution is necessary for acetal decomposition.
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Abstract
Description
すなわち、本発明は以下の通りである。
(ビニルオキシブチルグリシジルエーテルの合成)
撹拌機、温度計、滴下ロートを備えた3Lの筒型フラスコに4-ヒドロキシブチルビニルエーテル(丸善石油化学製 HBVE)1000g(8.61モル)、水酸化ナトリウム448g(11.2モル)を仕込んだ。撹拌しながら40℃まで温度を上げた後、エピクロロヒドリン1243g(13.4モル)を徐々に添加し、40℃~60℃で制御しながら反応を行った。反応8時間後、反応によって生成した塩化ナトリウムをろ過除去した後、ヘキサン1000gを入れて3%硫酸水素ナトリウム水溶液400gで洗浄し、さらに、17%食塩水800gで洗浄した。ロータリーエバポレータを用いて有機層を濃縮することによってヘキサンを留去した後、ろ過を行い、目的のビニルオキシブチルグリシジルエーテルを純度94%、収率94%で得た。このとき、得られた物質中に含まれる4-ヒドロキシブチルビニルエーテルは0.5%であった。
1Lの4つ口セパラブルフラスコにパラトルエンスルホン酸5.0g、純水140gを仕込み、攪拌機、温度計、空気導入管、冷却トラップ付き真空ポンプを設置した。攪拌をしながら、上記で合成したビニルオキシブチルグリシジルエーテル500gを液温が40℃で保たれるよう調節しながらフラスコへゆっくりと添加した。添加終了後、20kPaまで減圧し、乾燥空気を100ml/分で導入しながら1時間攪拌を続けた後、ガスクロマトグラフィーで反応液を分析したところ、ビニルオキシブチルグリシジルエーテルのピークは見られなかった。しかし、液体クロマトグラフィーによる分析ではアセタール二量体が5.2%生成していたため、0.04%パラトルエンスルホン酸水溶液26gを添加し、温度を40℃に保ったまま圧力を5kPaにしてアセタール分解反応を行った。反応1時間後に分析したところアセタール二量体のピークがほぼ消失していたため、反応を終了した。反応完了液に炭酸水素ナトリウム2.1gを入れて中和した後、系内の水をロータリーエバポレータで濃縮留去し、系内の水分が800ppm以下であることを確認後、濃縮液をろ過し、目的のブタンジオールモノグリシジルエーテルを純度92%、収率99%で得た。このとき、得られた物質中に含まれるブタンジオールは0.2%であり、アセタール二量体は検出されなかった。
ビニルオキシブチルグリシジルエーテルを合成後、減圧蒸留を行い、これをブタンジオールモノグリシジルエーテルの合成に使用すること以外は実施例1と同様の操作を行った。減圧蒸留は、圧力0.4kPaで行い、留出温度82℃であった。得られた精製ビニルオキシブチルグリシジルエーテルは純度99%、収率94%であった。また、脱ビニル化及びアセタール分解によって最終的に得られたブタンジオールモノグリシジルエーテルを純度95%、収率99%で得た。このとき、得られた物質中に含まれるブタンジオールは0.1%であり、アセタール二量体は検出されなかった。
撹拌機、撹拌機、温度計、滴下ロートを備えた1Lのフラスコに1,4-ブタンジオール300g(3.3モル)、水酸化ナトリウム132g(3.3モル)を仕込んだ。撹拌しながら40℃まで温度を上げた後、エピクロロヒドリン305g(3.3モル)を徐々に添加し、40℃~60℃で制御しながら反応を行った。反応3時間後、ガスクロマトグラフィーにより反応液を分析したところ、1,4-ブタンジオールの反応率は45%であった。この反応液に水600gと酢酸エチル300gで5回抽出し、さらに有機層を水200gで2回洗浄した。有機層をロータリーエバポレータで濃縮して酢酸エチルを留去した後、ろ過を行い、目的のブタンジオールモノグリシジルエーテルを純度87%、収率41%で得た。このとき、得られた物質中に含まれるブタンジオールは4%、ジグリシジルエーテル体は5%であり、さらにガスクロマトグラフィーでは複数の不明成分が検出された。
300mlの4つ口フラスコにエチレングリコール31.0g、パラトルエンスルホン酸0.03gを仕込み、攪拌機、温度計、空気導入管、冷却トラップ付き真空ポンプを設置した。攪拌をしながら、実施例1で合成したビニルオキシブチルグリシジルエーテル79gを反応圧力10kPaで液温が35℃で保たれるよう調節しながらフラスコへゆっくりと添加した。反応進行と共に生成するエチレングリコールメチルアセタールを連続的に留去した。反応3時間で、反応転化率が23%であったため、パラトルエンスルホン酸を0.3g追加添加して反応を行ったところ、追加から1時間後に反応転化率が100%となった。生成するエチレングリコールメチルアセタールがガスクロマトグラフィー上で検出されなくなるまで、さらに4時間撹拌を行った後、酸化マグネシウム0.5gを添加して中和し、ろ過を行った。目的のブタンジオールモノグリシジルエーテルを純度88%、収率94%で得た。このとき、液体クロマトグラフィーによる分析によって、得られた物質中にはブタンジオールモノグリシジルエーテルとエチレングリコールメチルアセタールとの反応生成物と考えられるピークが5.5%検出された。
1Lの4つ口セパラブルフラスコにパラトルエンスルホン酸5.0g、純水140gを仕込み、攪拌機、温度計、空気導入管、冷却トラップ付き真空ポンプを設置した。攪拌をしながら、実施例1で合成したビニルオキシブチルグリシジルエーテル500gを液温が40℃で保たれるよう調節しながらフラスコへゆっくりと添加した。添加終了後、20kPaまで減圧し、乾燥空気を100ml/分で導入しながら1時間攪拌を続けた後、ガスクロマトグラフィーで反応液を分析したところ、ビニルオキシブチルグリシジルエーテルのピークは見られなかった。反応液に炭酸水素ナトリウム2.1gを入れて中和した後、系内の水をロータリーエバポレータで濃縮留去し、系内の水分が800ppm以下であることを確認した。濃縮液をろ過し、目的のブタンジオールモノグリシジルエーテル純度85%、収率99%で得た。このとき、得られた物質中に含まれるブタンジオールは0.2%であり、アセタール二量体は7.2%であった。
比較例3では、アセタール分解反応をしなかったことのみが実施例1と異なり、当然ながらアセタール二量体が残存したままであり、合成したブタンジオールモノグリシジルエーテルの純度が実施例1及び2よりも劣っていた。
1Lの4つ口セパラブルフラスコにパラトルエンスルホン酸5.0g、純水140gを仕込み、攪拌機、温度計、空気導入管、冷却トラップ付き真空ポンプを設置した。攪拌をしながら、実施例1で合成したビニルオキシブチルグリシジルエーテル500gを液温が40℃で保たれるよう調節しながらフラスコへゆっくりと添加した。添加終了後、20kPaまで減圧し、乾燥空気を100ml/分で導入しながら1時間攪拌を続けた後、ガスクロマトグラフィーで反応液を分析したところ、ビニルオキシブチルグリシジルエーテルのピークは見られなかった。しかし、液体クロマトグラフィーによる分析ではアセタール二量体が5.3%生成していたため、純水26gを添加し、圧力を5kPaにしてアセタール分解反応を行った。反応1時間後に分析したところアセタール二量体のピークが5.2%でありほとんど変化していなかった。また、その後反応を継続してもアセタール二量体のピークは減少しなかった。
1Lの4つ口セパラブルフラスコにパラトルエンスルホン酸5.0g、純水140gを仕込み、攪拌機、温度計、空気導入管、冷却トラップ付き真空ポンプを設置した。攪拌をしながら、上記で合成したビニルオキシブチルグリシジルエーテル500gを液温が40℃で保たれるよう調節しながらフラスコへゆっくりと添加した。添加終了後、20kPaまで減圧し、乾燥空気を100ml/分で導入しながら1時間攪拌を続けた後、ガスクロマトグラフィーで反応液を分析したところ、ビニルオキシブチルメタクリレートのピークは見られなかった。しかし、液体クロマトグラフィーによる分析ではアセタール二量体が5.3%生成していたため、パラトルエンスルホン酸0.05g添加し、圧力を5kPaにしてアセタール分解反応を行った。反応1時間後に分析したところアセタール二量体のピークが5.1%でありほとんど変化していなかった。また、その後反応を継続してもアセタール二量体のピークは減少しなかった。
Claims (6)
- ビニルエーテル含有アルコールをエピハロヒドリンと反応させてビニルエーテル含有グリシジルエーテルとし、酸触媒及び水の存在下、脱ビニル化反応を行った後に、さらに酸水溶液を添加してアセタール分解反応を行う工程を含むことを特徴とするアルキルジオールモノグリシジルエーテルの製造方法。
- 脱ビニル化反応の反応系内の圧力が50kPa以下である、請求項1に記載のアルキルジオールモノグリシジルエーテルの製造方法。
- 脱ビニル化反応及びアセタール分解反応での反応系内の温度が10℃~60℃である、請求項1又は2に記載のアルキルジオールモノグリシジルエーテルの製造方法。
- アセタール分解反応での反応系内の圧力が20kPa以下である、請求項1~3のいずれか1項に記載のアルキルジオールモノグリシジルエーテルの製造方法。
- ビニルエーテル含有アルコールが4-ヒドロキシブチルビニルエーテルである、請求項1~5のいずれか1項に記載のアルキルジオールモノグリシジルエーテルの製造方法。
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201280036374.8A CN103702987B (zh) | 2011-07-22 | 2012-07-17 | 烷基二醇单缩水甘油基醚的制造方法 |
EP12817966.0A EP2735565B1 (en) | 2011-07-22 | 2012-07-17 | Method for producing alkyldiol monoglycidyl ether |
KR1020147001444A KR101610557B1 (ko) | 2011-07-22 | 2012-07-17 | 알킬디올모노글리시딜에테르의 제조 방법 |
US14/234,182 US9394265B2 (en) | 2011-07-22 | 2012-07-17 | Method for producing alkyldiol monoglycidyl ether |
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KR102662157B1 (ko) * | 2019-02-04 | 2024-05-14 | 아디트야 비를라 케미컬스 (타일랜드) 리미티드 | 재활용 및 재가공 가능한 에폭시 레진 |
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Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0899968A (ja) | 1994-09-30 | 1996-04-16 | Mitsubishi Chem Corp | エポキシ基を有する(メタ)アクリレートの製造方法 |
WO2006093281A1 (ja) * | 2005-03-03 | 2006-09-08 | Itochu Chemical Frontier Corporation | α-ヒドロキシ-ω-グリシジルエーテルの製造方法 |
JP4446651B2 (ja) | 2002-07-12 | 2010-04-07 | 四日市合成株式会社 | 高純度α−ヒドロキシ−ω−グリシジルエーテルの製造方法 |
WO2010064514A1 (ja) * | 2008-12-01 | 2010-06-10 | 日立化成工業株式会社 | ヒドロキシアルキル(メタ)アクリル酸エステルの製造方法 |
JP2011251941A (ja) * | 2010-06-02 | 2011-12-15 | Hitachi Chem Co Ltd | ヒドロキシアルキル(メタ)アクリル酸エステルの製造方法 |
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CN102060989A (zh) | 2010-11-18 | 2011-05-18 | 浙江皇马科技股份有限公司 | 一种缩水甘油醚基烯丙醇聚氧乙烯醚的制备方法 |
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Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0899968A (ja) | 1994-09-30 | 1996-04-16 | Mitsubishi Chem Corp | エポキシ基を有する(メタ)アクリレートの製造方法 |
JP4446651B2 (ja) | 2002-07-12 | 2010-04-07 | 四日市合成株式会社 | 高純度α−ヒドロキシ−ω−グリシジルエーテルの製造方法 |
WO2006093281A1 (ja) * | 2005-03-03 | 2006-09-08 | Itochu Chemical Frontier Corporation | α-ヒドロキシ-ω-グリシジルエーテルの製造方法 |
JP2006241081A (ja) | 2005-03-03 | 2006-09-14 | Itochu Chemical Frontier Corp | α−ヒドロキシ−ω−グリシジルエーテルの製造方法 |
WO2010064514A1 (ja) * | 2008-12-01 | 2010-06-10 | 日立化成工業株式会社 | ヒドロキシアルキル(メタ)アクリル酸エステルの製造方法 |
JP2011251941A (ja) * | 2010-06-02 | 2011-12-15 | Hitachi Chem Co Ltd | ヒドロキシアルキル(メタ)アクリル酸エステルの製造方法 |
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JP2013023479A (ja) | 2013-02-04 |
CN103702987B (zh) | 2016-03-30 |
TW201307310A (zh) | 2013-02-16 |
EP2735565A4 (en) | 2014-12-17 |
JP6092502B2 (ja) | 2017-03-08 |
TW201623269A (zh) | 2016-07-01 |
CN103702987A (zh) | 2014-04-02 |
EP2735565A1 (en) | 2014-05-28 |
TWI591061B (zh) | 2017-07-11 |
US9394265B2 (en) | 2016-07-19 |
US20140163246A1 (en) | 2014-06-12 |
KR101610557B1 (ko) | 2016-04-07 |
KR20140039306A (ko) | 2014-04-01 |
EP2735565B1 (en) | 2017-06-28 |
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