WO2011157561A1 - Inhaler - Google Patents

Inhaler Download PDF

Info

Publication number
WO2011157561A1
WO2011157561A1 PCT/EP2011/059091 EP2011059091W WO2011157561A1 WO 2011157561 A1 WO2011157561 A1 WO 2011157561A1 EP 2011059091 W EP2011059091 W EP 2011059091W WO 2011157561 A1 WO2011157561 A1 WO 2011157561A1
Authority
WO
WIPO (PCT)
Prior art keywords
inhaler
monitoring device
fluid
container
sensor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2011/059091
Other languages
English (en)
French (fr)
Inventor
Herbert Wachtel
Andree Jung
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim International GmbH
Original Assignee
Boehringer Ingelheim International GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim International GmbH filed Critical Boehringer Ingelheim International GmbH
Priority to ES11723062.3T priority Critical patent/ES2604482T3/es
Priority to EP11723062.3A priority patent/EP2582468B1/en
Priority to JP2013514626A priority patent/JP6067554B2/ja
Priority to PL16020261T priority patent/PL3108966T3/pl
Priority to US13/703,998 priority patent/US10155094B2/en
Priority to EP16020261.0A priority patent/EP3108966B1/en
Publication of WO2011157561A1 publication Critical patent/WO2011157561A1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/006—Sprayers or atomisers specially adapted for therapeutic purposes operated by applying mechanical pressure to the liquid to be sprayed or atomised
    • A61M11/007—Syringe-type or piston-type sprayers or atomisers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/02—Sprayers or atomisers specially adapted for therapeutic purposes operated by air or other gas pressure applied to the liquid or other product to be sprayed or atomised
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/008—Electronic counters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/0083—Timers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/0005—Components or details
    • B05B11/0037—Containers
    • B05B11/0039—Containers associated with means for compensating the pressure difference between the ambient pressure and the pressure inside the container, e.g. pressure relief means
    • B05B11/0044—Containers associated with means for compensating the pressure difference between the ambient pressure and the pressure inside the container, e.g. pressure relief means compensating underpressure by ingress of atmospheric air into the container, i.e. with venting means
    • B05B11/00446—Containers associated with means for compensating the pressure difference between the ambient pressure and the pressure inside the container, e.g. pressure relief means compensating underpressure by ingress of atmospheric air into the container, i.e. with venting means the means being located at the bottom of the container or of an enclosure surrounding the container
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/1042—Components or details
    • B05B11/108—Means for counting the number of dispensing strokes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0015—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
    • A61M2016/0018—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical
    • A61M2016/0021—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical with a proportional output signal, e.g. from a thermistor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0027—Accessories therefor, e.g. sensors, vibrators, negative pressure pressure meter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/332—Force measuring means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/35—Communication
    • A61M2205/3546—Range
    • A61M2205/3553—Range remote, e.g. between patient's home and doctor's office
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/82—Internal energy supply devices
    • A61M2205/8293—Solar
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/0005—Components or details
    • B05B11/0037—Containers
    • B05B11/0038—Inner container disposed in an outer shell or outer casing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/02—Membranes or pistons acting on the contents inside the container, e.g. follower pistons
    • B05B11/026—Membranes separating the content remaining in the container from the atmospheric air to compensate underpressure inside the container
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/109—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle the dispensing stroke being affected by the stored energy of a spring
    • B05B11/1091—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle the dispensing stroke being affected by the stored energy of a spring being first hold in a loaded state by locking means or the like, then released
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B12/00—Arrangements for controlling delivery; Arrangements for controlling the spray area
    • B05B12/004—Arrangements for controlling delivery; Arrangements for controlling the spray area comprising sensors for monitoring the delivery, e.g. by displaying the sensed value or generating an alarm
    • B05B12/006—Pressure or flow rate sensors
    • B05B12/008—Pressure or flow rate sensors integrated in or attached to a discharge apparatus, e.g. a spray gun
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B12/00—Arrangements for controlling delivery; Arrangements for controlling the spray area
    • B05B12/02—Arrangements for controlling delivery; Arrangements for controlling the spray area for controlling time, or sequence, of delivery
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B12/00—Arrangements for controlling delivery; Arrangements for controlling the spray area
    • B05B12/08—Arrangements for controlling delivery; Arrangements for controlling the spray area responsive to condition of liquid or other fluent material to be discharged, of ambient medium or of target ; responsive to condition of spray devices or of supply means, e.g. pipes, pumps or their drive means
    • B05B12/12—Arrangements for controlling delivery; Arrangements for controlling the spray area responsive to condition of liquid or other fluent material to be discharged, of ambient medium or of target ; responsive to condition of spray devices or of supply means, e.g. pipes, pumps or their drive means responsive to conditions of ambient medium or target, e.g. humidity, temperature position or movement of the target relative to the spray apparatus

Definitions

  • the monitoring device comprises a pressure sensor for measuring the air pressure in a housing of the inhaler or the monitoring device, particularly in a mouthpiece of the inhaler, for detecting inhalation.
  • a pressure sensor of very simple construction can be used instead of a flow sensor.
  • the pressure sensor can be arranged separately from the mouthpiece, in particular outside the mouthpiece, but preferably within the inhaler in another region, most preferably in the lower actuating or housing part. This preferred arrangement of the pressure sensor outside a path for supply air allows a particularly simple construction.
  • Fig. 1 is a schematic section through a proposed inhaler according to a first embodiment in the untensioned state
  • the monitoring device 24 preferably comprises an interface 39 for the transmission of data, particularly for inputting or outputting data, particularly for outputting data relating to the use of the inhaler 1 .
  • the interface 39 preferably operates optically or in the infrared range. This is particularly secure against unwanted listening-in or eavesdropping.
  • the data transmission may also be effected by any other method, for example by radio or electrical contact of the transmission device 24 or printed circuit board 25 or via another electrical connection such as a plug or the like.
  • For the issuing or transmission of data it is also possible to use generally known or special protocols or interfaces such as Bluetooth, USB, SATA or the like. Alternatively or additionally, the inductive transmission of data is also possible.
  • the monitoring device 24 After being switched on or activated or woken up, the monitoring device 24 measures the pressure (air pressure) preferably continuously or at short intervals, over and over again, by means of the pressure sensor 29.
  • the monitoring device 24 is thus designed particularly for determining a pressure pattern. If, after the tensioning of the inhaler 1 or after the monitoring device 24 has been switched on or activated, a user breaths in or inhales through the mouthpiece 13 or other delivery section of the inhaler 1 , air is sucked in through the supply air pathway 44. A reduced pressure is thereby produced in the inhaler 1 or mouthpiece 13. This reduced pressure is measured or detected or determined by the pressure sensor 29 which is fluidically or pressure-connected to the supply air pathway 44 or
  • the monitoring device 24 can also indicate to the user optically and/or acoustically, for example, how long and/or how powerfully he has to breath in and/or inhale and/or when the end of the (required) inhalation is reached.

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Mechanical Engineering (AREA)
  • Medicinal Preparation (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
PCT/EP2011/059091 2010-06-18 2011-06-01 Inhaler Ceased WO2011157561A1 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
ES11723062.3T ES2604482T3 (es) 2010-06-18 2011-06-01 Inhalador
EP11723062.3A EP2582468B1 (en) 2010-06-18 2011-06-01 Inhaler
JP2013514626A JP6067554B2 (ja) 2010-06-18 2011-06-01 吸入器
PL16020261T PL3108966T3 (pl) 2010-06-18 2011-06-01 Inhalator
US13/703,998 US10155094B2 (en) 2010-06-18 2011-06-01 Inhaler
EP16020261.0A EP3108966B1 (en) 2010-06-18 2011-06-01 Inhaler

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP10006334.6 2010-06-18
EP10006334 2010-06-18

Publications (1)

Publication Number Publication Date
WO2011157561A1 true WO2011157561A1 (en) 2011-12-22

Family

ID=43382538

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2011/059091 Ceased WO2011157561A1 (en) 2010-06-18 2011-06-01 Inhaler

Country Status (8)

Country Link
US (1) US10155094B2 (cg-RX-API-DMAC7.html)
EP (2) EP2582468B1 (cg-RX-API-DMAC7.html)
JP (2) JP6067554B2 (cg-RX-API-DMAC7.html)
DK (1) DK3108966T3 (cg-RX-API-DMAC7.html)
ES (2) ES2604482T3 (cg-RX-API-DMAC7.html)
HU (1) HUE051560T2 (cg-RX-API-DMAC7.html)
PL (1) PL3108966T3 (cg-RX-API-DMAC7.html)
WO (1) WO2011157561A1 (cg-RX-API-DMAC7.html)

Cited By (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8807131B1 (en) 2013-06-18 2014-08-19 Isonea Limited Compliance monitoring for asthma inhalers
NL2010405C2 (en) * 2013-03-07 2014-09-10 Medspray Xmems Bv Aerosol generator for generating an inhalation aerosol.
US10155094B2 (en) 2010-06-18 2018-12-18 Boehringer Ingelheim International Gmbh Inhaler
IT201700086905A1 (it) * 2017-07-28 2019-01-28 Amiko S R L Accessorio per inalatore, inalatore e metodo per rilevare un procedimento di somministrazione di farmaco
EP3498326A1 (de) * 2017-12-18 2019-06-19 Boehringer Ingelheim International GmbH Teilzähler für einen zerstäuber, zerstäuber und system mit einem zerstäuber und einer dockingstation
WO2019121386A1 (de) 2017-12-18 2019-06-27 Boehringer Ingelheim International Gmbh Vorrichtung zum versetzen eines inhalators in einen auslösebereiten zustand
CN110167619A (zh) * 2016-11-18 2019-08-23 诺顿（沃特福特）有限公司 具有电子元件的药物递送装置
CN110461394A (zh) * 2016-12-06 2019-11-15 诺顿（沃特福特）有限公司 具有集成电子模块的吸入装置
EP3305105B1 (en) 2012-05-14 2021-01-13 Nicoventures Trading Limited Electronic vapour provision device
EP3357356B1 (en) 2012-05-14 2021-02-17 Nicoventures Trading Limited Electronic vapour provision device
WO2021037462A1 (en) * 2019-08-23 2021-03-04 Igncyerto S.L. Dose measuring device and method in inhalers
EP3485930B1 (en) 2017-11-20 2021-04-14 Presspart Gmbh & Co. Kg Inhalation system
EP3678720A4 (en) * 2017-09-08 2021-05-26 Hcmed Innovations Co., Ltd. ATOMIZER AND NOZZLE ARRANGEMENT FOR IT
WO2021213876A1 (de) * 2020-04-22 2021-10-28 Aesculap Ag Intelligenter ölsprayadapter
US11419995B2 (en) 2019-04-30 2022-08-23 Norton (Waterford) Limited Inhaler system
CN116871078A (zh) * 2019-01-17 2023-10-13 阿普塔尔拉多尔夫策尔有限责任公司 用于排出液体、尤其是排出药用液体的分配器以及包括这种分配器的套件
US11944425B2 (en) 2014-08-28 2024-04-02 Norton (Waterford) Limited Compliance monitoring module for an inhaler
US12434022B2 (en) 2017-04-28 2025-10-07 Invox Belgium Nv Inhalation device and method
US12702164B2 (en) 2013-10-09 2026-08-11 Nicoventures Trading Limited Electronic vapor provision system having a sleep mode

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CA3176610A1 (en) 2012-06-25 2014-01-03 Gecko Health Innovations, Inc. Devices, systems, and methods for adherence monitoring and patient interaction
GB2507104A (en) 2012-10-19 2014-04-23 Nicoventures Holdings Ltd Electronic inhalation device
GB2507103A (en) 2012-10-19 2014-04-23 Nicoventures Holdings Ltd Electronic inhalation device
HK1222141A1 (zh) 2013-08-28 2017-06-23 杰科健康创新公司 用於遵守度监控的设备、系统和方法及用於监控消耗品分配器的使用的设备、系统和方法
US10828434B2 (en) * 2013-08-30 2020-11-10 Adherium (Nz) Limited Compliance monitor for a medicament inhaler
SE538264C2 (sv) * 2013-09-17 2016-04-19 Anders Blomberg Injektionsanordning för medicinska ändamål
CN103566444B (zh) * 2013-11-12 2015-04-15 江苏大学 一种医用盐雾测控仪及盐雾浓度定量控制方法
DE102014204939B3 (de) * 2014-03-17 2014-12-24 Aptar Radolfzell Gmbh Spender mit einer elektronische Betätigungserkennung
KR20170047321A (ko) 2014-08-28 2017-05-04 마이크로도스 테라퓨특스, 인코포레이티드 소형 압력 센서 활성화를 동반하는 주기적 건조 분말 흡입기
KR102631093B1 (ko) 2014-08-28 2024-01-29 노턴 (워터포드) 리미티드 호흡 작동식 흡입기의 순응도 모니터링 모듈
US11033694B2 (en) 2014-09-22 2021-06-15 Koninklijke Philips N.V. Inhaler with orientation sensor
GB201420039D0 (en) 2014-11-11 2014-12-24 Teva Uk Ltd System for training a user in administering a medicament
BR112017010605A2 (pt) * 2014-11-20 2018-02-14 Cognita Labs Llc método e aparelho para medir, facilitar e corrigir o uso de inaladores
US10058661B2 (en) 2014-12-04 2018-08-28 Norton (Waterford) Limited Inhalation monitoring system and method
EP3037120A1 (en) 2014-12-23 2016-06-29 PARI Pharma GmbH Aerosol delivery device and operating method for the aerosol delivery device
DE102015004073B3 (de) * 2015-03-30 2016-07-07 Meda Ab Pumpkappe für einen pharmazeutischen Behälter, Einsatz für eine Pumpkappe für einen pharmazeutischen Behälter, pharmazeutischer Behälter mit der Pumpkappe, und Computerprogrammprodukt
GB2540135B (en) 2015-07-01 2021-03-03 Nicoventures Holdings Ltd Electronic aerosol provision system
ES2745552T3 (es) 2015-07-20 2020-03-02 Pearl Therapeutics Inc Sistemas de administración de aerosol
EP3366095B1 (en) 2015-10-21 2021-04-21 Vertiv Corporation Cooling systems for small equipment rooms and methods of cooling small equipment rooms
US10434525B1 (en) * 2016-02-09 2019-10-08 Steven C. Cooper Electrostatic liquid sprayer usage tracking and certification status control system
GB2547279A (en) * 2016-02-15 2017-08-16 Univ Of Wales Trinity Saint David Inhaler device
ES2915559T3 (es) * 2016-02-17 2022-06-23 Adherium Nz Ltd Monitor de adherencia para un inhalador de medicamentos con tapa sujetada
CN109562236B (zh) * 2016-04-12 2022-04-26 生物合作制造公司 定量雾化吸入器附加设备，观察改善系统以及改善使用定量雾化吸入器中的观察的方法
FR3050116B1 (fr) * 2016-04-15 2020-05-15 Aptar France Sas Dispositif de distribution de produit fluide synchronise avec l'inhalation
WO2017205824A1 (en) 2016-05-27 2017-11-30 Proveris Scientific Corporation Devices and methods for using medicament devices
US20180085540A1 (en) * 2016-09-28 2018-03-29 Qualcomm Incorporated Inhaler with one or more visual sensors
IL266617B2 (en) 2016-11-18 2024-12-01 Norton Waterford Ltd Inhaler
FR3068894B1 (fr) * 2017-07-11 2019-08-09 Aptar France Sas Dispositif de distribution de produit fluide.
FR3069762B1 (fr) * 2017-08-03 2021-07-09 Aptar France Sas Dispositif de distribution de produit fluide.
JP7378400B2 (ja) 2017-12-28 2023-11-13 サノフイ 注射デバイスに取り付けるセンサデバイス
FR3077496B1 (fr) * 2018-02-06 2024-03-15 Nemera La Verpilliere Dispositif d’assistance a l’utilisation d’un dispositif de distribution a activation axiale
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ES2604482T3 (es) 2017-03-07
US10155094B2 (en) 2018-12-18
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