WO2011005839A1 - Pressure sensitive silicone adhesives with amphiphilic copolymers - Google Patents

Pressure sensitive silicone adhesives with amphiphilic copolymers Download PDF

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Publication number
WO2011005839A1
WO2011005839A1 PCT/US2010/041180 US2010041180W WO2011005839A1 WO 2011005839 A1 WO2011005839 A1 WO 2011005839A1 US 2010041180 W US2010041180 W US 2010041180W WO 2011005839 A1 WO2011005839 A1 WO 2011005839A1
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WO
WIPO (PCT)
Prior art keywords
pressure sensitive
silicone
oligomer
sensitive adhesive
amphiphilic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2010/041180
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English (en)
French (fr)
Inventor
Mahesh Sambasivam
Joseph C. Salamone
Ann Beal Salamone
Xiang Yu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Convatec Technologies Inc
Original Assignee
Convatec Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Convatec Technologies Inc filed Critical Convatec Technologies Inc
Priority to JP2012519694A priority Critical patent/JP5902084B2/ja
Priority to AU2010270603A priority patent/AU2010270603B2/en
Priority to EP10797769.6A priority patent/EP2451852B1/en
Priority to US13/382,227 priority patent/US10294317B2/en
Priority to CA2766116A priority patent/CA2766116C/en
Publication of WO2011005839A1 publication Critical patent/WO2011005839A1/en
Anticipated expiration legal-status Critical
Priority to US16/109,536 priority patent/US11426485B2/en
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/046—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2/00—Processes of polymerisation
    • C08F2/12—Polymerisation in non-solvents
    • C08F2/16—Aqueous medium
    • C08F2/18—Suspension polymerisation
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F230/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and containing phosphorus, selenium, tellurium or a metal
    • C08F230/04—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and containing phosphorus, selenium, tellurium or a metal containing a metal
    • C08F230/08—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and containing phosphorus, selenium, tellurium or a metal containing a metal containing silicon
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
    • C08G77/42—Block-or graft-polymers containing polysiloxane sequences
    • C08G77/442—Block-or graft-polymers containing polysiloxane sequences containing vinyl polymer sequences
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L83/00—Compositions of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon only; Compositions of derivatives of such polymers
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
    • C09J11/00—Features of adhesives not provided for in group C09J9/00, e.g. additives
    • C09J11/02—Non-macromolecular additives
    • C09J11/06—Non-macromolecular additives organic
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
    • C09J11/00—Features of adhesives not provided for in group C09J9/00, e.g. additives
    • C09J11/08—Macromolecular additives
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
    • C09J143/00—Adhesives based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and containing boron, silicon, phosphorus, selenium, tellurium, or a metal; Adhesives based on derivatives of such polymers
    • C09J143/04—Homopolymers or copolymers of monomers containing silicon
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
    • C09J183/00—Adhesives based on macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon, with or without sulfur, nitrogen, oxygen, or carbon only; Adhesives based on derivatives of such polymers
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
    • C09J183/00—Adhesives based on macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon, with or without sulfur, nitrogen, oxygen, or carbon only; Adhesives based on derivatives of such polymers
    • C09J183/04—Polysiloxanes
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
    • C09J183/00—Adhesives based on macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon, with or without sulfur, nitrogen, oxygen, or carbon only; Adhesives based on derivatives of such polymers
    • C09J183/10—Block or graft copolymers containing polysiloxane sequences
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
    • C09J7/00—Adhesives in the form of films or foils
    • C09J7/30—Adhesives in the form of films or foils characterised by the adhesive composition
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
    • C09J7/00—Adhesives in the form of films or foils
    • C09J7/30—Adhesives in the form of films or foils characterised by the adhesive composition
    • C09J7/38—Pressure-sensitive adhesives [PSA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00655—Plasters adhesive
    • A61F2013/00697—Plasters adhesive elastomer-, e.g. rubber- based
    • A61F2013/00702—Plasters adhesive elastomer-, e.g. rubber- based silicon-based
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/04—Acids; Metal salts or ammonium salts thereof
    • C08F220/06—Acrylic acid; Methacrylic acid; Metal salts or ammonium salts thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/52—Amides or imides
    • C08F220/54—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • C08F220/56—Acrylamide; Methacrylamide
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
    • C08G77/04—Polysiloxanes
    • C08G77/20—Polysiloxanes containing silicon bound to unsaturated aliphatic groups
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
    • C09J183/00—Adhesives based on macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon, with or without sulfur, nitrogen, oxygen, or carbon only; Adhesives based on derivatives of such polymers
    • C09J183/14—Adhesives based on macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon, with or without sulfur, nitrogen, oxygen, or carbon only; Adhesives based on derivatives of such polymers in which at least two but not all the silicon atoms are connected by linkages other than oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
    • C09J2483/00—Presence of polysiloxane

Definitions

  • Silicone pressure sensitive adhesives are widely used in transdermal drug delivery, wound dressings, scar dressings, and other healthcare applications. These adhesives are typically a condensation product of silicate resin and
  • PDMS polydimethylsiloxane
  • a reactive blend of vinyl- and hydride- containing PDMS and a silicate resin cured via hydrosilylation reaction Dow Corning Literature, Silicone Pressure Sensitive Adhesives (2002).
  • the present approach is to add a suitable amphiphilic silicone copolymer to a silicone pressure sensitive adhesive.
  • An ideal amphiphilic silicone copolymer suitable for such applications should possess high cohesive strength, high moisture vapor
  • MVTR transmission rate
  • high pressure sensitive adhesion to surfaces maintain adhesion even under moist conditions, and should not leach out components or leave a residue.
  • Commercially available amphiphilic silicone copolymers are typically based on grafted poly(ethylene glycol). These copolymers are low molecular weight liquids, which are typically used as surfactants or defoamers.
  • Graiver, et al. used aldehyde-functional silicones as reactive sites for vinyl copolymerization in the presence of a copper redox system (D. Graiver, G. T.
  • the present invention includes silicone pressure sensitive adhesive compositions having novel amphiphilic silicone copolymers.
  • the silicone pressure sensitive adhesive compositions according to the present invention are suitable for adhering to biological surfaces.
  • the pressure sensitive adhesive includes an amphiphilic copolymer that is a reaction product of at least one silicone monomer or oligomer and at least one hydrophilic or amphiphilic monomer or oligomer, such that the amphiphilic copolymer:
  • the silicone monomer is a methacryloylalkylsiloxysilane
  • vinylalkylsiloxysilane vinylalkoxysilane, and combinations thereof.
  • the silicone oligomer is polydimethylsiloxane with reactive groups selected from hydride, vinyl, methacrylate, acrylate, epoxy, carbinol, mercapto, acetoxy, amino, isocyanato, halide, hydroxyl, and combinations thereof.
  • the hydrophilic or amphiphilic monomer or oligomer is selected from acrylamides, N-alkylacrylamides, N,N-dialkylacrylamides, N- alkylaminoalkylacrylamides, methacrylamides, acrylic acid and its esters and salts, methacrylic acid and its esters and salts, amino methacrylates, N-alkylamino acrylates, N-alkylamino methacrylates, maleic anhydride and its derivatives, alkenyl anhdyride and its derivatives, vinyl ethers, reactive polyethers, polyisocyanates, polyesters, polyamides, polypeptides, polysaccharides, polyurethanes, and combinations thereof.
  • a silicone pressure sensitive adhesive composition as described above is suitable for adhering medical devices to biological surfaces when it comprises 0.1 - 100% of an amphiphilic copolymer of at least one silicone monomer or oligomer and at least one hydrophilic or amphiphilic monomer or oligomer that does not leach out in the presence of moisture.
  • Such an adhesive is applicable for adhering medical devices, such as ostomy appliances, wound dressings, securement devices for surgical devices, intravenous delivery devices, catheters and infusion devices to human skin.
  • amphiphilic copolymer structure is a block, alternating, random, branched, grafted, or a combination.
  • a silicone pressure sensitive adhesive is blended with a sufficient amount of amphiphilic silicone copolymer so as to yield an adhesive that stays adhered under moist conditions and will not leach the copolymer in moisture.
  • the invention also includes the synthesis of an amphiphilic silicone copolymer that is a pressure sensitive adhesive by itself.
  • amphiphilic copolymers are based on a polymehzable silicone monomer copolymehzed with hydrophilic and/or amphiphilic monomers.
  • the typical procedure for the synthesis of the poly(TRIS)-based random copolymers, via free radical polymerization, is as follows, using poly(TRIS-co-N,N'- dimethylaminoethyl methacrylate)(DMAEMA) (3:1 wt) as an example: 4.5g TRIS and 1.5g of DMAEMA were added into a 25ml_ pressure resistant reaction flask. Then 0.045g VAZO 67 was transferred into the flask. To the flask was then added 14g ethyl acetate to afford a 30 wt % solution. The mixture was gently shaken until a clear solution was obtained.
  • DMAEMA poly(TRIS-co-N,N'- dimethylaminoethyl methacrylate)
  • TRIS copolymers were made with methacrylic acid (MAA), N- vinylcaprolactam (NVCL), N-isopropylacrylamide (NIPAM), N- hydroxyethylacrylamide (NHEA), and methacrylate-terminated PDMS.
  • MAA methacrylic acid
  • NVCL N- vinylcaprolactam
  • NIPAM N-isopropylacrylamide
  • NHEA N- hydroxyethylacrylamide
  • methacrylate-terminated PDMS methacrylate-terminated PDMS.
  • silicone gel adhesive containing amphiphilic copolymer is as follows. A 1 :1 ratio of NuSiI MED-6345 Part A and Part B were taken. Then poly(TRIS-co-NIPAM) (3:1 monomer wt ratio) solution in HMDS was added so that the adhesive gel would eventually contain 5 wt % of solid copolymer. The mixture was thoroughly stirred and then coated on a polyurethane film and allowed to dry for 1 hour for evaporation of solvent. Later the adhesive was cured at 6O 0 C in the oven for 3 hours.
  • the copolymer was dissolved in HMDS, coated onto to a polyurethane film and then dried in the oven.
  • a 1 -inch by 1.5-inch strip of the adhesive was tested on human subject for adhesion under dry and wet environment.
  • dry adhesion the tape was secured to the abdominal area for 8 hours prior to removal.
  • wet adhesion the tape was attached to abdominal skin of the human subject and then tape removed after an aerobic activity for 40-60 minutes.
  • Table 1 The results of the adhesion studies under dry and wet conditions are shown in Table 1.
  • MED 6345 is a two-part tacky silicone gel from Nusil Technology.
  • VAZO 67 is a free radical initiator from Du Pont. Adhesives, 2, 4 and 5 are sufficient to secure an ostomy appliance, wound dressing, infusion device or other securement device to human skin. Other Inventive Examples:
  • the wet adhesive strength was measured using a tongue depressor which had been soaked in water for 5 min (and dipped in water and taken out before each measurement).
  • the polymer films were cast from 20 wt% solutions in ethyl acetate, dried for 5 h, and equilibrated at 35 0 C in the incubator overnight in a moist environment, then taken out and immediately measured. (The wet adhesion for all other materials was measured this way unless otherwise mentioned.)
  • PDMS-macromonomer purchased from Gelest, Inc.
  • Tables 1 -7 indicate that the pressure sensitive adhesives with amphiphilic copolymers of the present invention adhere well under dry and wet conditions. Furthermore, adhesion of these compositions to skin shows an improvement over silicone adhesives without the copolymers.

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Materials For Medical Uses (AREA)
  • Graft Or Block Polymers (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Silicon Polymers (AREA)
PCT/US2010/041180 2009-07-07 2010-07-07 Pressure sensitive silicone adhesives with amphiphilic copolymers Ceased WO2011005839A1 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP2012519694A JP5902084B2 (ja) 2009-07-07 2010-07-07 両親媒性コポリマーを有する感圧シリコーン接着剤
AU2010270603A AU2010270603B2 (en) 2009-07-07 2010-07-07 Pressure sensitive silicone adhesives with amphiphilic copolymers
EP10797769.6A EP2451852B1 (en) 2009-07-07 2010-07-07 Pressure sensitive silicone adhesives with amphiphilic copolymers
US13/382,227 US10294317B2 (en) 2009-07-07 2010-07-07 Pressure sensitive adhesives with amphiphilic copolymers
CA2766116A CA2766116C (en) 2009-07-07 2010-07-07 Pressure sensitive silicone adhesives with amphiphilic copolymers
US16/109,536 US11426485B2 (en) 2009-07-07 2018-08-22 Pressure sensitive adhesives with amphiphilic copolymer

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US22353409P 2009-07-07 2009-07-07
US61/223,534 2009-07-07
US22802309P 2009-07-23 2009-07-23
US61/228,023 2009-07-23

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US13/382,227 A-371-Of-International US10294317B2 (en) 2009-07-07 2010-07-07 Pressure sensitive adhesives with amphiphilic copolymers
US16/109,536 Continuation US11426485B2 (en) 2009-07-07 2018-08-22 Pressure sensitive adhesives with amphiphilic copolymer

Publications (1)

Publication Number Publication Date
WO2011005839A1 true WO2011005839A1 (en) 2011-01-13

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PCT/US2010/041180 Ceased WO2011005839A1 (en) 2009-07-07 2010-07-07 Pressure sensitive silicone adhesives with amphiphilic copolymers
PCT/US2010/041191 Ceased WO2011005846A1 (en) 2009-07-07 2010-07-07 Amphiphilic silicone copolymers for pressure sensitive adhesive applications

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Country Status (6)

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US (3) US10294317B2 (enExample)
EP (2) EP2451883B1 (enExample)
JP (3) JP2012532960A (enExample)
AU (2) AU2010270603B2 (enExample)
CA (2) CA2766120C (enExample)
WO (2) WO2011005839A1 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012103181A1 (en) * 2011-01-25 2012-08-02 Convatec Technologies Inc. Methods to improve the blending of amphiphilic copolymers such as tris-nipam into silicone gel adhesive
ES2604196A1 (es) * 2017-01-23 2017-03-03 Universidade De Santiago Hidrogeles para administración de fármacos inhibidores de aldosa reductasa
CN107699186A (zh) * 2017-10-09 2018-02-16 南京图艾生物医药科技有限公司 一种改性医用硅橡胶压敏胶及其制备方法
US10294317B2 (en) 2009-07-07 2019-05-21 Convatec Technologies Inc. Pressure sensitive adhesives with amphiphilic copolymers

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL1871433T3 (pl) 2005-03-24 2009-09-30 Nolabs Ab Zabieg kosmetyczny z tlenkiem azotu, urządzenie do wykonywania tego zabiegu i sposób jego wytwarzania
JP2010031271A (ja) * 2008-07-02 2010-02-12 Yazaki Corp シリコーン表面処理水酸化マグネシウム
CN102711729B (zh) 2009-08-21 2015-04-01 诺万公司 局部用凝胶
US8777903B2 (en) * 2010-10-22 2014-07-15 Carefusion 2200, Inc. Catheter patch applicator assembly
WO2013006608A1 (en) 2011-07-05 2013-01-10 Novan, Inc. Topical compositions
CN103814099B (zh) 2011-08-17 2016-11-23 3M创新有限公司 具有吸收纤维的疏水性粘合剂
JP6265967B2 (ja) * 2012-03-14 2018-01-24 ノヴァン，インコーポレイテッド 医薬組成物
EP2831149B1 (en) 2012-03-28 2016-01-20 Dow Corning Corporation Amphiphilic resin-linear organosiloxane block copolymers
US20140121747A1 (en) * 2012-10-25 2014-05-01 Boston Scientific Scimed, Inc. Stent having a tacky silicone coating to prevent stent migration
US9855211B2 (en) 2013-02-28 2018-01-02 Novan, Inc. Topical compositions and methods of using the same
JP6513667B2 (ja) 2013-08-08 2019-05-15 ノヴァン，インコーポレイテッド 局所用組成物およびそれを使用する方法
US10206947B2 (en) 2013-08-08 2019-02-19 Novan, Inc. Topical compositions and methods of using the same
CA2963294A1 (en) * 2014-10-09 2016-04-14 Coloplast A/S Composition comprising a polymer and a switch initiator
US11512237B2 (en) 2015-11-20 2022-11-29 Dow Silicones Corporation Room temperature curable compositions
GB201520461D0 (en) * 2015-11-20 2016-01-06 Dow Corning Water pick up sealant
EP3423100A4 (en) 2016-03-02 2019-10-16 Novan, Inc. COMPOSITIONS FOR THE TREATMENT OF INFLAMMATION AND METHOD FOR THE TREATMENT THEREOF
JP6899845B2 (ja) 2016-04-13 2021-07-07 ノヴァン，インコーポレイテッド 感染症を治療するための組成物、システム、キットおよび方法
US10758734B2 (en) 2017-02-28 2020-09-01 Boston Scientific Neuromodulation Corporation Implantable medical device with a silicone housing
CN111601545B (zh) 2017-11-09 2024-05-07 康沃特克科技公司 造口术监测系统和方法
CN111417705B (zh) 2017-12-21 2022-01-25 美国陶氏有机硅公司 包含硅酮材料的织物护理组合物
JP7364565B2 (ja) 2017-12-21 2023-10-18 ダウ シリコーンズ コーポレーション シリコーン材料を含む化粧品組成物
JP2021515807A (ja) 2018-03-01 2021-06-24 ノーバン，インク． 一酸化窒素放出性坐剤及びその使用の方法
USD893514S1 (en) 2018-11-08 2020-08-18 11 Health And Technologies Limited Display screen or portion thereof with graphical user interface
CN110684504B (zh) * 2019-10-31 2022-04-01 广东莱尔新材料科技股份有限公司 一种用于线缆的耐高温的粘结剂和耐高温胶膜
CA3198681A1 (en) 2020-10-15 2022-04-21 Convatec Technologies Inc. Ostomy systems and methods
CN117729949A (zh) * 2021-07-27 2024-03-19 康沃特克有限公司 间歇性导管
CN117651572A (zh) * 2021-07-27 2024-03-05 康沃特克有限公司 间歇性导管
CN114369201A (zh) * 2022-01-30 2022-04-19 成都太合生物材料有限公司 一种双亲有机硅共聚物及其制备方法和应用
KR102644268B1 (ko) * 2023-03-19 2024-03-07 류양렬 수액팩 커버용 차광필름커버

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5045060A (en) * 1989-04-26 1991-09-03 Therex Corp. Implantable infusion device
US5103812A (en) * 1988-10-12 1992-04-14 Rochal Industries, Inc. Conformable bandage and coating material
US20040102744A1 (en) * 2002-11-27 2004-05-27 Fattman George F. Ostomy pouch attachment adhesives resistant to stomal effluent
US7014627B2 (en) * 2002-08-15 2006-03-21 Venetec International, Inc. Catheter securement device
US20080268242A1 (en) * 2003-12-22 2008-10-30 3M Innovative Properties Company Silicone pressure sensitive adhesive and articles
US20090114342A1 (en) * 2004-10-28 2009-05-07 Shunji Aoki Silicone composition and a pressure sensitive adhesive film having a pressure sensitive adhesive layer made from the composition

Family Cites Families (198)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4584356A (en) * 1984-11-02 1986-04-22 General Electric Company Method for making silicone-organic block polymers
JPS61291607A (ja) * 1985-06-17 1986-12-22 Sunstar Inc 歯科用接着性コーティングベース組成物
US4693935A (en) * 1986-05-19 1987-09-15 Minnesota Mining And Manufacturing Company Polysiloxane-grafted copolymer pressure sensitive adhesive composition and sheet materials coated therewith
US5214119A (en) * 1986-06-20 1993-05-25 Minnesota Mining And Manufacturing Company Block copolymer, method of making the same, dimaine precursors of the same, method of making such diamines and end products comprising the block copolymer
US4900809A (en) * 1989-03-13 1990-02-13 Gaf Chemicals Corporation Process of rendering copolymers of maleic anhydride and alkyl vinyl ethers prepared in benzene solvent substantially benzene-free
US4981903A (en) * 1989-08-07 1991-01-01 Minnesota Mining And Manufacturing Company Polysiloxane-grafter copolymer topical binder composition with novel hydrophilic monomers and method of coating therewith
JPH0611683B2 (ja) * 1990-07-09 1994-02-16 富士システムズ株式会社 歯科用接着剤
US5082913A (en) * 1990-07-25 1992-01-21 Isp Investments Inc. Terpolymers of maleic anhydride, alkyl vinyl ethers and isobutylene and crosslinked products thereof
BR9306363A (pt) * 1992-05-15 1998-06-30 Procter & Gamble Agente adesivo contendo polímero enxertado com polissiloxana e composições cosméticas do mesmo
US5756572A (en) * 1995-07-24 1998-05-26 Dow Corning Corporation Silicone pressure sensitive adhesive composition containing thermoplastic multi-segmented copolymer
US5886119A (en) * 1995-08-08 1999-03-23 Olin Microelectronic Chemicals, Inc. Terpolymers containing organosilicon side chains
DE19820151A1 (de) * 1998-05-06 1999-11-11 Hexal Ag Transdermales therapeutisches System zur Anwendung von Candesartan
WO2000024573A1 (en) * 1998-10-28 2000-05-04 The Regents Of The University Of California Modular, energy-dissipating material and method for using it
US6201055B1 (en) * 1999-03-11 2001-03-13 Dow Corning Corporation Silicone composition and silicone pressure sensitive adhesive
ATE502657T1 (de) * 2001-05-01 2011-04-15 Av Topchiev Inst Petrochemical Zweiphasige, wasserabsorbierende bioadhäsive zusammenstezung
US7422577B2 (en) 2003-06-27 2008-09-09 Hollister Incorporated Lubricating deodorant for ostomy pouches
US20070078197A1 (en) * 2003-10-07 2007-04-05 Coloplast A/S Adhesive composition and use of such composition
JP4134082B2 (ja) * 2004-04-09 2008-08-13 株式会社資生堂 ブラシ状交互共重合体及びその製造方法
US7429633B2 (en) * 2004-04-09 2008-09-30 Shiseido Company, Ltd. Brush-form alternative copolymer and process for producing the same
US7258661B2 (en) 2004-09-13 2007-08-21 Bristol-Myers Squibb Company Stoma plug
US7247692B2 (en) * 2004-09-30 2007-07-24 Johnson & Johnson Vision Care, Inc. Biomedical devices containing amphiphilic block copolymers
SE0403092D0 (sv) * 2004-12-20 2004-12-20 Amo Groningen Bv Amphiphilic block copolymers and their use
BRPI0519586A2 (pt) * 2004-12-20 2009-02-25 Amo Groningen Bv copolÍmeros de bloco anfifÍlicos e seu uso
KR100652425B1 (ko) * 2005-08-12 2006-12-01 삼성전자주식회사 포토레지스트용 탑 코팅 조성물과 이를 이용한포토레지스트 패턴 형성 방법
AU2007312985B2 (en) 2006-10-17 2013-05-30 C. R. Bard, Inc. Waste management system
WO2008134334A1 (en) 2007-04-24 2008-11-06 Bristol-Myers Squibb Company Closure system for a drainable pouch
BRPI0812404A2 (pt) 2007-06-12 2014-12-02 Convatec Technologies Inc Dispositivo de ostomia
US10646370B2 (en) 2008-04-01 2020-05-12 Donaldson Company, Inc. Enclosure ventilation filter and assembly method
US8979811B2 (en) 2008-04-01 2015-03-17 Donaldson Company, Inc. Enclosure ventilation filter and assembly method
WO2010045042A2 (en) 2008-10-17 2010-04-22 Sterigear LLC Bodily fluid drainage assembly
BR122019006922B8 (pt) 2008-11-12 2021-06-22 Coloplast As revestimento convexo para uso numa placa de base de um dispositivo de ostomia
WO2010124187A2 (en) * 2009-04-24 2010-10-28 Henkel Corporation Silicone acrylic hybrid polymer-based adhesives
AU2010270603B2 (en) * 2009-07-07 2015-05-07 Convatec Technologies Inc. Pressure sensitive silicone adhesives with amphiphilic copolymers
US9314365B2 (en) 2009-07-14 2016-04-19 B. Braun Medical Sas Ostomy port gas release mechanism
HUE045768T2 (hu) 2009-07-14 2020-01-28 Braun Medical Sztómafedél
WO2011008166A1 (en) 2009-07-17 2011-01-20 Milux Holding S.A. Absorbing sealing device for an intestinal stoma
AU2010292291B2 (en) 2009-09-11 2016-06-09 Convatec Technologies Inc. Controlled discharge ostomy appliance and shield therefor
EP4509166A3 (en) 2010-04-12 2025-04-16 Implantica Patent Ltd System for treating a patient having an intestinal disorder
EP2575704B1 (en) 2010-06-04 2016-09-14 Coloplast A/S An ostomy bag with a filter construction
US8460259B2 (en) 2010-11-02 2013-06-11 Convatec Technologies, Inc. Controlled discharge ostomy appliance and moldable adhesive wafer
EP3998052A1 (en) 2010-12-17 2022-05-18 Coloplast A/S A convex supporting device for an ostomy appliance
US8449513B2 (en) 2010-12-27 2013-05-28 Benson Turtleneck Barrier, Llc Ostomy barrier seal
CN108578044A (zh) 2011-03-17 2018-09-28 康沃特克科技公司 高阻隔性弹性体粪便导管或造口袋
EP2819628A4 (en) 2012-02-29 2015-12-09 Hollister Inc BUBBLE FUEL COMPOSITIONS FOR SKIN-RELATED PRODUCTS AND MANUFACTURING METHOD THEREFOR
US10470936B2 (en) 2012-02-29 2019-11-12 Hollister Incorporated Buffered adhesive compositions for skin-adhering medical products
CN109172104A (zh) 2012-05-10 2019-01-11 B·布劳恩医学股份有限公司 造口术器具
US9265648B2 (en) 2012-05-15 2016-02-23 Hollister Incorporated Odor barrier film
PL2854723T3 (pl) 2012-05-25 2017-12-29 Coloplast A/S Warstwa zapewniająca komfort dla worka zbierającego
EP2668935A1 (en) 2012-05-31 2013-12-04 Hollister Incorporated An ostomy pouch
WO2014086369A1 (en) 2012-12-06 2014-06-12 Coloplast A/S An adaptable ostomy base plate
US10322024B2 (en) 2013-01-23 2019-06-18 Hollister Incorporated Multilayer film including foam layer and ostomy products made therefrom
EP3278773B1 (en) 2013-01-29 2020-09-02 Coloplast A/S Ostomy appliance
US9050387B2 (en) 2013-02-07 2015-06-09 Hollister Incorporated Sound absorbing ostomy pouch
GB2512655B (en) 2013-04-05 2017-10-25 Salts Healthcare Ltd Ostomy appliance
US10617554B2 (en) 2013-04-30 2020-04-14 Donna E. Luce Adapter insert for an ostomy guard
JP6463736B2 (ja) 2013-05-17 2019-02-06 ホリスター・インコーポレイテッドＨｏｌｌｉｓｔｅｒ Ｉｎｃｏｒｐｏｒａｔｅｄ 生分解性臭気バリアフィルム
FR3007964A1 (fr) 2013-07-02 2015-01-09 Braun B Med Sas Poche destinee a recueillir des urines
RU2653990C2 (ru) 2013-07-18 2018-05-15 Колопласт А/С Отображение прикосновения
GB2516470B (en) 2013-07-23 2020-03-18 Welland Medical Ltd Expandable ostomy bag
HK1225267A1 (zh) 2013-07-23 2017-09-08 Convatec Technologies Inc. 可成型粘结晶片
BR112016002257A2 (pt) 2013-08-01 2017-12-12 Convatec Technologies Inc conector de saco de fechamento automático
HUE049128T2 (hu) 2013-12-30 2020-09-28 Hollister Inc Csomagolás osztómiás gátgyûrûhöz
GB2522416B (en) 2014-01-22 2020-07-22 Welland Medical Ltd Flange extender comprising honey
GB2549060B (en) 2014-01-22 2020-09-23 Welland Medical Ltd Ostomy bag filter with adhesive webbing
WO2015116651A1 (en) 2014-01-28 2015-08-06 Hollister Incorporated Ostomy faceplate including invertible stoma collar
DK177977B1 (da) 2014-03-04 2015-02-09 Jørgen-Ulrik Brandt Lyd reducerende stomipose
DK3116559T3 (da) 2014-03-11 2020-03-30 Hollister Inc Asymmetrisk flerlagsfilm til stomianvendelse
LT3122555T (lt) 2014-03-26 2020-03-10 Hollister Incorporated Daugiasluoksnė plėvelė, apimanti putų ir dujų barjerinį sluoksnį
US10531977B2 (en) 2014-04-17 2020-01-14 Coloplast A/S Thermoresponsive skin barrier appliances
WO2015164832A1 (en) 2014-04-24 2015-10-29 Convatec Technologies Inc. Ostomy pouch filter system
WO2015180731A1 (en) 2014-05-28 2015-12-03 Coloplast A/S An ostomy wafer
US10653551B2 (en) 2014-06-23 2020-05-19 Entremous, Llc Methods and apparatuses for ostomy gas management
ES2804687T3 (es) 2014-06-24 2021-02-09 Hollister Inc Película multicapa que incluye capa de barrera al olor que tiene propiedades de amortiguación de sonido
LT2962966T (lt) 2014-07-02 2018-01-10 Kiefel Gmbh Įrenginys, skirtas gaminti medicinos produktą ir būdas, kaip tą įrenginį naudoti
RU2694469C2 (ru) 2014-07-16 2019-07-15 Колопласт А/С Дренируемый сборный мешок
GB2528302B (en) 2014-07-17 2020-08-19 Welland Medical Ltd Ostomy bag
FR3024439B1 (fr) 2014-07-29 2017-07-21 M3At Sa Poche comportant un clapet de securite
EP3187198A4 (en) 2014-08-08 2018-04-25 Alcare Co., Ltd. Moldable composition for skin applications
NL2013602B1 (nl) 2014-10-09 2016-09-01 Stomydo B V Inrichting voor het reinigen van een stoma in een menselijk of dierlijk lichaam.
AU2015343293A1 (en) 2014-11-03 2017-05-25 Fistula Solution Corporation Containment devices for treatment of intestinal fistulas and complex wounds
GB201419881D0 (en) 2014-11-07 2014-12-24 Salts Healthcare Ltd Ostomy appliance
EP3215075B1 (en) 2014-12-12 2019-05-29 Secretary, Department Of Biotechnology Ostomy management device
GB2536001B (en) 2015-03-02 2019-11-13 Salts Healthcare Ltd Urostomy appliance
US10441455B2 (en) 2015-04-02 2019-10-15 Mayo Foundation For Medical Education And Research Continent ostomy valve and method of use
US10729806B2 (en) 2015-04-30 2020-08-04 Coloplast A/S Adhesive composition
EP3636290B1 (en) 2015-08-24 2023-07-12 Coloplast A/S An adhesive composition
AU2016320081B2 (en) 2015-09-11 2020-09-03 Coloplast A/S Ostomy device
GB201517205D0 (en) 2015-09-29 2015-11-11 Optimum Medical Soutions Ltd Cover means and method of use thereof
WO2017067558A1 (en) 2015-10-20 2017-04-27 Coloplast A/S An ostomy appliance
BR112018007792A2 (pt) 2015-10-20 2018-10-30 Coloplast As membro lateral de corpo de um aparelho de estomia, aparelho de estomia, e, método de aplicação de um aparelho de estomia
WO2017074731A1 (en) 2015-10-30 2017-05-04 C.R. Bard, Inc. Vent adaptor assemblies, methods of making the same, methods of using the same, and urinary drainage bag systems using the same
US10537462B1 (en) 2015-11-06 2020-01-21 Wildhatch, LLC Colostomy appliance with flushable insert
US10478328B2 (en) 2015-12-07 2019-11-19 Liney Guidry Ostomy pouch replacement device
US20200046542A1 (en) 2015-12-07 2020-02-13 Theresa Johnson Ostomy Pouch Replacement Device
PL3389741T3 (pl) 2015-12-17 2020-11-02 Coloplast A/S Awaryjne zatrzymanie dla systemu do irygacji odbytniczej i/lub stomijnej
WO2017106911A1 (en) 2015-12-24 2017-06-29 Jason Jit-Sun Tan Customisable stoma insert
US10463527B2 (en) 2016-01-19 2019-11-05 Velcro BVBA Configuring elastic supports
EP3375416B1 (en) 2016-01-29 2020-05-13 Álvarez Ponce, Carlos Eduardo Sphincter-type intestinal valve
CA3013462C (en) 2016-02-05 2021-10-05 Hollister Incorporated Retractable outlet for ostomy pouch
WO2017141190A1 (en) 2016-02-18 2017-08-24 Mracna Aaron J Ostomy pouch vent and method of venting an ostomy pouch
RU2734911C2 (ru) 2016-03-11 2020-10-26 Колопласт А/С Адгезивная прокладка с высвобождающей подложкой
GB2548673B (en) 2016-03-21 2019-11-27 Pelican Healthcare Ltd An adhesive securing member for an ostomy product
GB2548892A (en) 2016-03-31 2017-10-04 Univ Limerick An ostomy attachment for use in reducing the incidence of chemical dermatitis
EP3439589B1 (en) 2016-04-07 2020-06-10 Technische Universiteit Eindhoven Plasma-assisted odour-free regulation of gas pressure inside stoma bag
CN109069689A (zh) 2016-04-13 2018-12-21 科洛普拉斯特公司 用于施加粘合剂的方法
USD862691S1 (en) 2016-05-12 2019-10-08 Marlen Manufacturing And Development Co. Ostomy pouch
GB2550936B (en) 2016-06-01 2020-03-04 Trio Healthcare Ltd Discharge solidifier and malodour control
WO2017222780A1 (en) 2016-06-20 2017-12-28 Hollister Incorporated Peristomal support belt
CN109641083A (zh) 2016-09-02 2019-04-16 科洛普拉斯特公司 分层膜
EP3515380B1 (en) 2016-09-21 2023-06-07 Coloplast A/S Ostomy device
US10758398B2 (en) 2016-11-01 2020-09-01 Covidien Lp Apparatus and associated methodologies for creating a stoma
CA3041061A1 (en) 2016-11-21 2018-05-24 Hollister Incorporated Ostomy barrier
US20200046543A1 (en) 2016-11-22 2020-02-13 Hollister Incorporated Drainage system for ostomy pouch
WO2018106871A1 (en) 2016-12-07 2018-06-14 Emory University Deodorizing compositions, ostomy devices, and uses thereof
JP7069157B2 (ja) 2016-12-16 2022-05-17 アヴェント インコーポレイテッド 医療用プラグシステム及び装置
JP6226409B1 (ja) 2017-01-17 2017-11-08 株式会社エクセルシア コロストミー用排泄物処理剤
WO2018136793A1 (en) 2017-01-20 2018-07-26 Hollister Incorporated Drainable ostomy pouch
US10449081B2 (en) 2017-02-18 2019-10-22 Choon Kee Lee Ostomy apparatus
US10792472B2 (en) 2017-02-22 2020-10-06 Covidien Lp Apparatus and associated methodologies for creating a stoma
GB2560497A (en) 2017-02-24 2018-09-19 Welland Medical Ltd Flange for ostomy bag
US10660785B2 (en) 2017-03-31 2020-05-26 Hamilton Sundstrand Corporation Long duration waste management system
US20200229962A1 (en) 2017-04-05 2020-07-23 Hollister Incorporated Drainable ostomy pouch outlet
CN110494104B (zh) 2017-04-10 2022-04-19 科洛普拉斯特公司 造口术器具的体侧构件
US11534326B2 (en) 2017-04-10 2022-12-27 Coloplast A/S Body side member of an ostomy appliance
RU2019135072A (ru) 2017-04-10 2021-05-11 Колопласт А/С Обращенный к телу элемент приспособления для стомы
EP4454622A3 (en) 2017-04-10 2024-12-25 Coloplast A/S Body side member of an ostomy appliance
WO2018188709A1 (en) 2017-04-10 2018-10-18 Coloplast A/S Irrigation system with mechanical fluid pressure control
WO2018200721A1 (en) 2017-04-25 2018-11-01 The Regents Of The Univesity Of Colorado, A Body Corporated Dressing for enteral and vesical access devices and related methods
US20200078206A1 (en) 2017-05-05 2020-03-12 Zoni Llc Protection Device for Ostomy Pouch
GB2564377A (en) 2017-05-25 2019-01-16 Welland Medical Ltd Film
DK179423B1 (da) 2017-05-31 2018-06-18 Multi Lock Aps Stomianordning
EP3634324B1 (en) 2017-06-08 2025-08-13 Hollister Incorporated Skin barrier including skin friendly ingredients
TWI666008B (zh) 2017-07-17 2019-07-21 林志豪 造口接合儲存裝置
GB2566725B (en) 2017-09-22 2022-02-23 Salts Healthcare Ltd A drainable ostomy appliance
GB2566723B (en) 2017-09-22 2022-02-23 Salts Healthcare Ltd A drainable ostomy appliance
GB2566721B (en) 2017-09-22 2020-07-15 Salts Healthcare Ltd An ostomy appliance
GB2566722B (en) 2017-09-22 2022-02-23 Salts Healthcare Ltd A drainable ostomy appliance
GB201715394D0 (en) 2017-09-22 2017-11-08 Salts Healthcare Ltd An ostomy appliance
GB2566724B (en) 2017-09-22 2022-02-23 Salts Healthcare Ltd A drainable ostomy appliance
GB201715388D0 (en) 2017-09-22 2017-11-08 Salts Healthcare Ltd An ostomy appliance
GB2566719B (en) 2017-09-22 2022-03-16 Salts Healthcare Ltd A drainable ostomy appliance
US20200276045A1 (en) 2017-10-29 2020-09-03 Technion Research And Development Foundation Limited Temporary stoma evacuation device
US10610402B1 (en) 2017-11-03 2020-04-07 Olajire Idowu Stoma prolapse prosthesis
US11583431B2 (en) 2017-11-08 2023-02-21 Coloplast A/S Kit of parts and a complementary-material element for an ostomy appliance
WO2019091528A1 (en) 2017-11-08 2019-05-16 Coloplast A/S An adhesive wafer with a neutralizer matrix
RU2020117768A (ru) 2017-11-08 2021-12-08 Колопласт А/С Клейкая пластина с матрицей с нейтрализатором
CA3081899A1 (en) 2017-11-08 2019-05-16 Coloplast A/S Complementary-material element for an ostomy appliance
US20210186740A1 (en) 2017-11-08 2021-06-24 Coloplast A/S Complementary material dispenser in a body waste collecting appliance and an ostomy appliance system
CN111601545B (zh) 2017-11-09 2024-05-07 康沃特克科技公司 造口术监测系统和方法
CA3080013C (en) 2017-11-15 2023-08-22 Hollister Incorporated Buffered adhesive compositions for skin-adhering medical products
WO2019120442A1 (en) 2017-12-22 2019-06-27 Coloplast A/S Sensor assembly part and a base plate for an ostomy appliance and a device for connecting to a base plate or a sensor assembly part
WO2019120425A1 (en) 2017-12-22 2019-06-27 Coloplast A/S Ostomy appliance system, monitor device, and method of monitoring an ostomy appliance
EP3727245B1 (en) 2017-12-22 2025-04-30 Coloplast A/S SCHEMES FOR TRANSMITTING DATA FROM AN OSTOMY SYSTEM, MONITORING DEVICE FOR AN OSTOMY APPLIANCE, AND RELATED METHODS
US11918506B2 (en) 2017-12-22 2024-03-05 Coloplast A/S Medical appliance with selective sensor points and related methods
JP7282781B2 (ja) 2017-12-22 2023-05-29 コロプラスト アクティーゼルスカブ 角度範囲漏出検出機能を備えるオストミー装具
EP3727225B1 (en) 2017-12-22 2024-05-08 Coloplast A/S System including a skin-engageable element of an ostomy appliance
US10799385B2 (en) 2017-12-22 2020-10-13 Coloplast A/S Ostomy appliance with layered base plate
US11872108B2 (en) 2017-12-22 2024-01-16 Coloplast A/S Medical appliance with electrode multiplexing and related methods
US11471318B2 (en) 2017-12-22 2022-10-18 Coloplast A/S Data collection schemes for a medical appliance and related methods
WO2019120434A1 (en) 2017-12-22 2019-06-27 Coloplast A/S Processing schemes for an ostomy system, monitor device for an ostomy appliance and related methods
US10500084B2 (en) 2017-12-22 2019-12-10 Coloplast A/S Accessory devices of an ostomy system, and related methods for communicating leakage state
EP4275663A3 (en) 2017-12-22 2024-01-17 Coloplast A/S Moisture detecting base plate for an ostomy appliance and a system for determining moisture propagation in a base plate and/or a sensor assembly part
WO2019120443A1 (en) 2017-12-22 2019-06-27 Coloplast A/S Sensor assembly part and a base plate for an ostomy appliance and a method for manufacturing a base plate or a sensor assembly part
LT3727227T (lt) 2017-12-22 2023-07-25 Coloplast A/S Ostomijos prietaiso pagrindo plokštė ir pagrindo plokštės jutiklių montavimo dalis ir pagrindo plokštės ir jutiklių montavimo dalies gamybos būdas
US11998473B2 (en) 2017-12-22 2024-06-04 Coloplast A/S Tools and methods for cutting holes in a medical appliance
EP3727224B1 (en) 2017-12-22 2022-11-02 Coloplast A/S Base plate and sensor assembly part of an ostomy system having a moisture sensor
US11627891B2 (en) 2017-12-22 2023-04-18 Coloplast A/S Calibration methods for medical appliance tools
EP3727222B1 (en) 2017-12-22 2024-05-08 Coloplast A/S Sensor assembly part for an ostomy appliance and a method for manufacturing a sensor assembly part
AU2018391393B2 (en) 2017-12-22 2024-08-22 Coloplast A/S Coupling part with a hinge for an ostomy base plate and sensor assembly part
EP3727226B1 (en) 2017-12-22 2024-08-21 Coloplast A/S Ostomy system and monitor device with angular leakage detection
WO2019120445A1 (en) 2017-12-22 2019-06-27 Coloplast A/S Base plate and sensor assembly of an ostomy system having a leakage sensor
EP4074291A1 (en) 2017-12-22 2022-10-19 Coloplast A/S Base plate for an ostomy appliance
WO2019120451A1 (en) 2017-12-22 2019-06-27 Coloplast A/S Base plate and a sensor assembly part for an ostomy appliance and a method for manufacturing a base plate and sensor assembly part
EP3996106B1 (en) 2017-12-22 2025-10-22 Coloplast A/S Monitor device of an ostomy system and associated method for operating a monitor device
CN111447896B (zh) 2017-12-22 2023-03-28 科洛普拉斯特公司 用于造口术器具的底板、用于造口术器具的监测装置和系统
US11590015B2 (en) 2017-12-22 2023-02-28 Coloplast A/S Sensor assembly part and a base plate for a medical appliance and a method for manufacturing a sensor assembly part and a base plate
DK3727240T4 (da) 2017-12-22 2025-03-24 Coloplast As Hjælpeanordninger til et stomisystem og tilhørende fremgangsmåder til kommunikering af funktionstilstand
EP4595934A3 (en) 2017-12-22 2025-11-05 Coloplast A/S Monitor device of an ostomy system having a connector for coupling to both a base plate and an accessory device
EP3773366A1 (en) 2018-04-09 2021-02-17 Swiss Safe Collect SA Pouch comprising a safety valve and a detachable sample holder
WO2019198012A1 (en) 2018-04-10 2019-10-17 Association For The Advancement Of Tissue Engineering And Cell Based Technologies & Therapies A4Tec - Associação Medical device for controlling the release of waste content from a subject, uses and method thereof
GB201806045D0 (en) 2018-04-12 2018-05-30 Ostomycure As Lid
GB2570526B (en) 2018-04-20 2020-05-20 Hocknull Inch Anne Device for stoma bag and improved stoma flange and bag
US20190321213A1 (en) 2018-04-23 2019-10-24 Robert Allen Morrison, SR. Adjustable Waterproof Barrier For An Ostomy Appliance
WO2019221830A1 (en) 2018-05-17 2019-11-21 Hollister Incorporated Ostomy collection and drainage system
US11033420B2 (en) 2018-05-28 2021-06-15 Shelby Blatt Ostomy pouch holding system
GB201809053D0 (en) 2018-06-01 2018-07-18 Ostoform Ltd Improvements in ostomy attachments
GB201809012D0 (en) 2018-06-01 2018-07-18 Ostoform Ltd Ostomy Bag
US11801156B2 (en) 2018-06-21 2023-10-31 Coloplast A/S Anti-reflux component for a stomal output collecting bag
US20200000624A1 (en) 2018-06-28 2020-01-02 Jennifer Gibbons Ostomy Leakage Alert System
WO2020008470A1 (en) 2018-07-05 2020-01-09 Ganguly Subir A wearable device for body fluid discharge
EP4233808B1 (en) 2018-07-10 2024-04-10 Hollister Incorporated Ostomy pouch filter
CN109009637B (zh) 2018-07-10 2022-03-15 振德医疗用品股份有限公司 造口排泄物收集装置
ES2737862B2 (es) 2018-07-16 2021-02-25 Fundacion Para La Investigacion Biomedica Del Hospital Univ La Paz Fibhulp Dispositivo de corte automatico de discos de ostomia
US20200038227A1 (en) 2018-07-31 2020-02-06 Thomas Makar, JR. Colostomy bag spacer assembly
US20200038229A1 (en) 2018-08-06 2020-02-06 Covidien Lp Stomal support device
US20200038228A1 (en) 2018-08-06 2020-02-06 Covidien Lp Connection devices for ostomy procedures
JP7460603B2 (ja) 2018-08-15 2024-04-02 コロプラスト アクティーゼルスカブ オストミーシステムの付属デバイス及び問題識別の関連方法
US11291576B2 (en) 2018-08-17 2022-04-05 Jordan Miller Disposable stoma plug and method of use thereof

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5103812A (en) * 1988-10-12 1992-04-14 Rochal Industries, Inc. Conformable bandage and coating material
US5045060A (en) * 1989-04-26 1991-09-03 Therex Corp. Implantable infusion device
US7014627B2 (en) * 2002-08-15 2006-03-21 Venetec International, Inc. Catheter securement device
US20040102744A1 (en) * 2002-11-27 2004-05-27 Fattman George F. Ostomy pouch attachment adhesives resistant to stomal effluent
US20080268242A1 (en) * 2003-12-22 2008-10-30 3M Innovative Properties Company Silicone pressure sensitive adhesive and articles
US20090114342A1 (en) * 2004-10-28 2009-05-07 Shunji Aoki Silicone composition and a pressure sensitive adhesive film having a pressure sensitive adhesive layer made from the composition

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP2451852A4 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10294317B2 (en) 2009-07-07 2019-05-21 Convatec Technologies Inc. Pressure sensitive adhesives with amphiphilic copolymers
WO2012103181A1 (en) * 2011-01-25 2012-08-02 Convatec Technologies Inc. Methods to improve the blending of amphiphilic copolymers such as tris-nipam into silicone gel adhesive
ES2604196A1 (es) * 2017-01-23 2017-03-03 Universidade De Santiago Hidrogeles para administración de fármacos inhibidores de aldosa reductasa
WO2018134467A1 (es) * 2017-01-23 2018-07-26 Universidade De Santiago De Compostela Hidrogeles para administración de fármacos inhibidores de aldosa reductasa
CN107699186A (zh) * 2017-10-09 2018-02-16 南京图艾生物医药科技有限公司 一种改性医用硅橡胶压敏胶及其制备方法

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CA2766116A1 (en) 2011-01-13
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CA2766116C (en) 2017-12-05
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CA2766120C (en) 2018-08-14
US8679581B2 (en) 2014-03-25
EP2451883A4 (en) 2014-07-02
JP5902084B2 (ja) 2016-04-13
JP2012532960A (ja) 2012-12-20
US20120108749A1 (en) 2012-05-03
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US20180362690A1 (en) 2018-12-20
JP6215874B2 (ja) 2017-10-18

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