WO2009140802A8 - 检测探针、通用寡核苷酸芯片及核酸检测方法及其用途 - Google Patents

检测探针、通用寡核苷酸芯片及核酸检测方法及其用途 Download PDF

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Publication number
WO2009140802A8
WO2009140802A8 PCT/CN2008/001695 CN2008001695W WO2009140802A8 WO 2009140802 A8 WO2009140802 A8 WO 2009140802A8 CN 2008001695 W CN2008001695 W CN 2008001695W WO 2009140802 A8 WO2009140802 A8 WO 2009140802A8
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WO
WIPO (PCT)
Prior art keywords
nucleic acid
probe pairs
sample
test probe
mutation
Prior art date
Application number
PCT/CN2008/001695
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English (en)
French (fr)
Other versions
WO2009140802A1 (zh
Inventor
唐一通
陈超
崔亚丽
朱娟丽
余龙林
高怡文
李铮
Original Assignee
陕西北美基因股份有限公司
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Application filed by 陕西北美基因股份有限公司 filed Critical 陕西北美基因股份有限公司
Priority to US12/994,017 priority Critical patent/US8501459B2/en
Publication of WO2009140802A1 publication Critical patent/WO2009140802A1/zh
Publication of WO2009140802A8 publication Critical patent/WO2009140802A8/zh

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
PCT/CN2008/001695 2008-05-23 2008-10-06 检测探针、通用寡核苷酸芯片及核酸检测方法及其用途 WO2009140802A1 (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US12/994,017 US8501459B2 (en) 2008-05-23 2008-10-06 Test probes, common oligonucleotide chips, nucleic acid detection method, and their uses

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN200810097700.1A CN101586150B (zh) 2008-05-23 2008-05-23 检测探针、通用寡核苷酸芯片及核酸检测方法及其用途
CN200810097700.1 2008-05-23

Publications (2)

Publication Number Publication Date
WO2009140802A1 WO2009140802A1 (zh) 2009-11-26
WO2009140802A8 true WO2009140802A8 (zh) 2010-12-09

Family

ID=41339723

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2008/001695 WO2009140802A1 (zh) 2008-05-23 2008-10-06 检测探针、通用寡核苷酸芯片及核酸检测方法及其用途

Country Status (3)

Country Link
US (1) US8501459B2 (zh)
CN (1) CN101586150B (zh)
WO (1) WO2009140802A1 (zh)

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KR101322880B1 (ko) * 2011-03-04 2013-10-29 한국과학기술원 Ｓｄｌ－ｐｃｒ을 이용한 유전자 분석방법
EP2766498B1 (en) 2011-10-14 2019-06-19 President and Fellows of Harvard College Sequencing by structure assembly
US11021737B2 (en) 2011-12-22 2021-06-01 President And Fellows Of Harvard College Compositions and methods for analyte detection
CA2859761C (en) 2011-12-22 2023-06-20 President And Fellows Of Harvard College Compositions and methods for analyte detection
WO2013184754A2 (en) 2012-06-05 2013-12-12 President And Fellows Of Harvard College Spatial sequencing of nucleic acids using dna origami probes
CN103667039B (zh) * 2012-09-10 2015-05-27 中国科学院上海微系统与信息技术研究所 一种用于基因检测的质量型传感器及其制备方法和应用
EP2971184B1 (en) 2013-03-12 2019-04-17 President and Fellows of Harvard College Method of generating a three-dimensional nucleic acid containing matrix
EP3603679B1 (en) 2013-06-04 2022-08-10 President and Fellows of Harvard College Rna-guided transcriptional regulation
CN103760355B (zh) 2013-12-05 2015-09-16 博奥生物集团有限公司 微阵列芯片检测中核苷酸序列的颗粒标记方法
JP6580331B2 (ja) * 2015-01-30 2019-09-25 倉敷紡績株式会社 一本鎖ｄｎａ産物の調製方法
WO2017079406A1 (en) 2015-11-03 2017-05-11 President And Fellows Of Harvard College Method and apparatus for volumetric imaging of a three-dimensional nucleic acid containing matrix
CN116200465A (zh) 2016-04-25 2023-06-02 哈佛学院董事及会员团体 用于原位分子检测的杂交链反应方法
JP7239465B2 (ja) 2016-08-31 2023-03-14 プレジデント アンド フェローズ オブ ハーバード カレッジ 蛍光ｉｎ ｓｉｔｕ配列決定による検出のための核酸配列ライブラリの作製法
EP4428536A2 (en) 2016-08-31 2024-09-11 President and Fellows of Harvard College Methods of combining the detection of biomolecules into a single assay using fluorescent in situ sequencing
CN106399589B (zh) * 2016-09-30 2020-03-27 广州易活生物科技有限公司 一种用于病毒基因分型检测的探针组合、试剂盒以及方法
US10415080B2 (en) 2016-11-21 2019-09-17 Nanostring Technologies, Inc. Chemical compositions and methods of using same
SG11202011274YA (en) 2018-05-14 2020-12-30 Nanostring Technologies Inc Chemical compositions and methods of using same
CN112400016A (zh) * 2018-06-26 2021-02-23 Tdk株式会社 用于检测dna的试剂盒与方法
SG11202101934SA (en) 2018-07-30 2021-03-30 Readcoor Llc Methods and systems for sample processing or analysis
WO2020076976A1 (en) 2018-10-10 2020-04-16 Readcoor, Inc. Three-dimensional spatial molecular indexing
CN111621551B (zh) * 2019-07-31 2021-10-26 深圳闪量科技有限公司 多重连接探针微阵列检测
CN111321203A (zh) * 2020-03-18 2020-06-23 杭州广科安德生物科技有限公司 核酸检测试剂盒及其应用
CN112345506B (zh) * 2020-11-06 2022-08-26 济南大学 一种检测汞离子的荧光生物传感器
WO2022107814A1 (ja) * 2020-11-18 2022-05-27 株式会社イクスフォレストセラピューティクス 変異プロファイリングのためのｒｎａプローブ及びその使用
CN113215223B (zh) * 2021-05-28 2022-10-18 生捷科技(杭州)有限公司 一种snp分型检测方法
CN113151405B (zh) * 2021-05-28 2022-09-09 生捷科技(杭州)有限公司 一种snp分型检测方法
CN114150088B (zh) * 2021-11-30 2024-06-25 广东医科大学 一种新冠病毒基因单碱基突变检测方法及其应用
CN116855366B (zh) * 2023-08-19 2024-10-18 北京航空航天大学 一种代谢指纹图谱可视化的细胞芯片及应用方法

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CN1556223A (zh) * 2004-01-08 2004-12-22 中国科学院武汉病毒研究所 一种基因芯片上寡核苷酸连接检测基因突变的方法
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CA2651815A1 (en) * 2006-05-10 2007-11-22 Dxterity Diagnostics Detection of nucleic acid targets using chemically reactive oligonucleotide probes
CN1896284B (zh) * 2006-06-30 2013-09-11 博奥生物有限公司 一种鉴别等位基因类型的方法

Also Published As

Publication number Publication date
US8501459B2 (en) 2013-08-06
US20110218115A1 (en) 2011-09-08
CN101586150A (zh) 2009-11-25
CN101586150B (zh) 2016-09-28
WO2009140802A1 (zh) 2009-11-26

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