WO2009028661A1 - 分子識別材料及びその製造方法 - Google Patents

分子識別材料及びその製造方法 Download PDF

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Publication number
WO2009028661A1
WO2009028661A1 PCT/JP2008/065526 JP2008065526W WO2009028661A1 WO 2009028661 A1 WO2009028661 A1 WO 2009028661A1 JP 2008065526 W JP2008065526 W JP 2008065526W WO 2009028661 A1 WO2009028661 A1 WO 2009028661A1
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WO
WIPO (PCT)
Prior art keywords
molecule
recognizing material
molecule recognizing
core particle
producing
Prior art date
Application number
PCT/JP2008/065526
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English (en)
French (fr)
Inventor
Hiroshi Ugajin
Haruma Kawaguchi
Norio Ueno
Original Assignee
Keio University
Shiseido Company Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Keio University, Shiseido Company Ltd. filed Critical Keio University
Priority to JP2009530204A priority Critical patent/JP4558097B2/ja
Priority to US12/674,923 priority patent/US20110021347A1/en
Priority to EP08828825A priority patent/EP2198952A4/en
Priority to CN200880104930A priority patent/CN101808726A/zh
Publication of WO2009028661A1 publication Critical patent/WO2009028661A1/ja

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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02Making microcapsules or microballoons
    • B01J13/20After-treatment of capsule walls, e.g. hardening
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02Making microcapsules or microballoons
    • B01J13/06Making microcapsules or microballoons by phase separation
    • B01J13/14Polymerisation; cross-linking
    • B01J13/18In situ polymerisation with all reactants being present in the same phase
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26Synthetic macromolecular compounds
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26Synthetic macromolecular compounds
    • B01J20/261Synthetic macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26Synthetic macromolecular compounds
    • B01J20/268Polymers created by use of a template, e.g. molecularly imprinted polymers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/305Addition of material, later completely removed, e.g. as result of heat treatment, leaching or washing, e.g. for forming pores
    • B01J20/3057Use of a templating or imprinting material ; filling pores of a substrate or matrix followed by the removal of the substrate or matrix
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/32Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3206Organic carriers, supports or substrates
    • B01J20/3208Polymeric carriers, supports or substrates
    • B01J20/321Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions involving only carbon to carbon unsaturated bonds
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/32Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268Macromolecular compounds
    • B01J20/327Polymers obtained by reactions involving only carbon to carbon unsaturated bonds
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/32Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3291Characterised by the shape of the carrier, the coating or the obtained coated product
    • B01J20/3293Coatings on a core, the core being particle or fiber shaped, e.g. encapsulated particles, coated fibers
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F257/00Macromolecular compounds obtained by polymerising monomers on to polymers of aromatic monomers as defined in group C08F12/00
    • C08F257/02Macromolecular compounds obtained by polymerising monomers on to polymers of aromatic monomers as defined in group C08F12/00 on to polymers of styrene or alkyl-substituted styrenes
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F291/00Macromolecular compounds obtained by polymerising monomers on to macromolecular compounds according to more than one of the groups C08F251/00 - C08F289/00
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F293/00Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule
    • C08F293/005Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule using free radical "living" or "controlled" polymerisation, e.g. using a complexing agent

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Graft Or Block Polymers (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)

Abstract

 形態の制御が可能で、且つ鋳型分子の選択性及び捕捉効率に優れた新規の分子識別材料、及びその簡便な製造方法を提供する。  すなわち、本発明にかかる分子識別材料は、コア粒子表面にシェル層を備えたコア-シェル粒子であり、前記シェル層に鋳型分子がインプリントされていることを特徴とする。  また、本発明にかかる分子識別材料の製造方法は、下記工程を含むことを特徴とする。 (a)コア粒子表面にイニファータ基を導入する工程、 (b)(a)工程後、鋳型分子を前記コア粒子表面に吸着させる工程、 (c)(b)工程後、前記コア粒子表面にシェル層を形成する工程。  
PCT/JP2008/065526 2007-08-30 2008-08-29 分子識別材料及びその製造方法 WO2009028661A1 (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2009530204A JP4558097B2 (ja) 2007-08-30 2008-08-29 分子識別材料及びその製造方法
US12/674,923 US20110021347A1 (en) 2007-08-30 2008-08-29 Molecule Recognizing Material And Process For Producing The Molecule Recognizing Material
EP08828825A EP2198952A4 (en) 2007-08-30 2008-08-29 MOLECULAR KNOWN MATERIAL AND METHOD FOR PRODUCING MOLECULAR KNOWN MATERIAL
CN200880104930A CN101808726A (zh) 2007-08-30 2008-08-29 分子识别材料和其制造方法

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-224772 2007-08-30
JP2007224772 2007-08-30

Publications (1)

Publication Number Publication Date
WO2009028661A1 true WO2009028661A1 (ja) 2009-03-05

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PCT/JP2008/065526 WO2009028661A1 (ja) 2007-08-30 2008-08-29 分子識別材料及びその製造方法

Country Status (6)

Country Link
US (1) US20110021347A1 (ja)
EP (2) EP2198952A4 (ja)
JP (1) JP4558097B2 (ja)
KR (1) KR101013679B1 (ja)
CN (1) CN101808726A (ja)
WO (1) WO2009028661A1 (ja)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013027863A (ja) * 2011-06-20 2013-02-07 Japan Atomic Energy Agency 金属吸着材とその製造方法及び金属吸着材を用いた金属捕集方法
JP2015102506A (ja) * 2013-11-27 2015-06-04 昶夫 宮下 液体クロマトグラフィ用充填剤
WO2015182296A1 (ja) * 2014-05-29 2015-12-03 株式会社日立製作所 臨床検査キット及び化学物質検出方法
WO2017046836A1 (ja) * 2015-09-14 2017-03-23 株式会社日立製作所 化学分析装置
JP2017083293A (ja) * 2015-10-28 2017-05-18 日立化成株式会社 分離材及びその製造方法
JP2017122596A (ja) * 2016-01-05 2017-07-13 日立化成株式会社 分離材及びその製造方法、並びにカラム
WO2018117067A1 (ja) * 2016-12-20 2018-06-28 学校法人 芝浦工業大学 分子インプリント高分子を表面に有する粒子を用いたセンサ
CN113351180A (zh) * 2021-06-08 2021-09-07 东北电力大学 一种温度响应型仿生锂离子印迹复合膜的制备方法及应用

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9138383B1 (en) * 2004-04-28 2015-09-22 The Regents Of The University Of Colorado, A Body Corporate Nanogel materials and methods of use thereof
CN102504320B (zh) * 2011-09-23 2014-03-26 上海化工研究院 一种超高分子量聚乙烯表面光引发可控自由基聚合接枝的方法
US9320465B2 (en) 2012-06-25 2016-04-26 International Business Machines Corporation Bio-chips and nano-biochips
EP2930509B1 (en) * 2012-12-06 2018-07-04 Daicel Corporation Separating agent
CN103506093B (zh) * 2013-09-30 2015-07-01 西安交通大学 一种磁性双模板蛋白质分子印迹纳米粒子及其制备方法
CN105903452B (zh) * 2016-05-26 2018-10-23 东南大学 一种芳香磺酸选择性离子交换树脂的制备方法
RU2702659C1 (ru) * 2018-12-14 2019-10-09 Федеральное государственное бюджетное учреждение науки Ордена Трудового Красного Знамени Институт нефтехимического синтеза им. А.В. Топчиева Российской академии наук (ИНХС РАН) Способ оценки стабильности железосодержащей дисперсии

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003509550A (ja) * 1999-09-17 2003-03-11 エムアイピー・テクノロジーズ・エービー 固体支持体上にグラフトされた新規な分子的にインプリントされたポリマー

Family Cites Families (3)

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JPH09127116A (ja) * 1995-11-01 1997-05-16 Agency Of Ind Science & Technol タンパク質分子識別機能を有する物質
SE9903958D0 (sv) * 1999-11-02 1999-11-02 Boerje Sellergren Porous materials for selective binding or transport of molecular guests
GB0015449D0 (en) * 2000-06-23 2000-08-16 Prometic Biosciences Limited Molecular imprinting

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003509550A (ja) * 1999-09-17 2003-03-11 エムアイピー・テクノロジーズ・エービー 固体支持体上にグラフトされた新規な分子的にインプリントされたポリマー

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013027863A (ja) * 2011-06-20 2013-02-07 Japan Atomic Energy Agency 金属吸着材とその製造方法及び金属吸着材を用いた金属捕集方法
JP2015102506A (ja) * 2013-11-27 2015-06-04 昶夫 宮下 液体クロマトグラフィ用充填剤
WO2015182296A1 (ja) * 2014-05-29 2015-12-03 株式会社日立製作所 臨床検査キット及び化学物質検出方法
WO2017046836A1 (ja) * 2015-09-14 2017-03-23 株式会社日立製作所 化学分析装置
JPWO2017046836A1 (ja) * 2015-09-14 2018-03-29 株式会社日立製作所 化学分析装置
JP2017083293A (ja) * 2015-10-28 2017-05-18 日立化成株式会社 分離材及びその製造方法
JP2017122596A (ja) * 2016-01-05 2017-07-13 日立化成株式会社 分離材及びその製造方法、並びにカラム
WO2018117067A1 (ja) * 2016-12-20 2018-06-28 学校法人 芝浦工業大学 分子インプリント高分子を表面に有する粒子を用いたセンサ
JPWO2018117067A1 (ja) * 2016-12-20 2019-10-24 学校法人 芝浦工業大学 分子インプリント高分子を表面に有する粒子を用いたセンサ
US11913899B2 (en) 2016-12-20 2024-02-27 Shibaura Institute Of Technology Sensor using particles coated with molecularly imprinted polymer
CN113351180A (zh) * 2021-06-08 2021-09-07 东北电力大学 一种温度响应型仿生锂离子印迹复合膜的制备方法及应用

Also Published As

Publication number Publication date
KR101013679B1 (ko) 2011-02-10
EP2198952A1 (en) 2010-06-23
EP2500088A3 (en) 2012-11-14
KR20100066478A (ko) 2010-06-17
JP4558097B2 (ja) 2010-10-06
JPWO2009028661A1 (ja) 2010-12-02
EP2500088A2 (en) 2012-09-19
CN101808726A (zh) 2010-08-18
US20110021347A1 (en) 2011-01-27
EP2198952A4 (en) 2011-04-27

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