WO2008142862A1 - 血管内皮前駆細胞の移植による抗がん療法 - Google Patents
血管内皮前駆細胞の移植による抗がん療法 Download PDFInfo
- Publication number
- WO2008142862A1 WO2008142862A1 PCT/JP2008/001247 JP2008001247W WO2008142862A1 WO 2008142862 A1 WO2008142862 A1 WO 2008142862A1 JP 2008001247 W JP2008001247 W JP 2008001247W WO 2008142862 A1 WO2008142862 A1 WO 2008142862A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- cells
- progenitor cells
- vascular
- vascular epithelial
- epithelial progenitor
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/44—Vessels; Vascular smooth muscle cells; Endothelial cells; Endothelial progenitor cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Vascular Medicine (AREA)
- Biotechnology (AREA)
- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12/600,530 US8491887B2 (en) | 2007-05-18 | 2008-05-19 | Anticancer therapy by transplanting vascular endothelial progenitor cells |
EP08751765A EP2163250B1 (en) | 2007-05-18 | 2008-05-19 | Anticancer therapy by transplanting vascular endothelial progenitor cells |
JP2009515092A JP5339533B2 (ja) | 2007-05-18 | 2008-05-19 | 血管内皮前駆細胞の移植による抗がん療法 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007133486 | 2007-05-18 | ||
JP2007-133486 | 2007-05-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2008142862A1 true WO2008142862A1 (ja) | 2008-11-27 |
Family
ID=40031581
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2008/001247 WO2008142862A1 (ja) | 2007-05-18 | 2008-05-19 | 血管内皮前駆細胞の移植による抗がん療法 |
Country Status (4)
Country | Link |
---|---|
US (1) | US8491887B2 (ja) |
EP (1) | EP2163250B1 (ja) |
JP (1) | JP5339533B2 (ja) |
WO (1) | WO2008142862A1 (ja) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010116665A1 (ja) * | 2009-04-07 | 2010-10-14 | 国立大学法人旭川医科大学 | 単核球由来の新規血管再生細胞群及びその分化誘導法 |
WO2012020566A1 (ja) | 2010-08-10 | 2012-02-16 | 国立大学法人旭川医科大学 | Ape1遺伝子導入による高機能化幹細胞・前駆細胞 |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5725489B2 (ja) * | 2008-06-27 | 2015-05-27 | 公立大学法人大阪市立大学 | 医療用組成物および医療用キット |
SG177651A1 (en) * | 2009-07-13 | 2012-03-29 | Biogencell Ltd | Method for using directing cells for specific stem/progenitor cell activation and differentiation |
EP2752471A4 (en) | 2011-08-31 | 2015-05-27 | Pentel Kk | OILED INK COMPOSITION FOR A BALL PEN |
US8956870B2 (en) | 2012-01-19 | 2015-02-17 | Biogencell, Ltd. | Method for using directing cells for specific stem/progenitor cell activation and differentiation |
CN108823149B (zh) * | 2018-07-26 | 2022-01-04 | 海南医学院 | 一种人外周血源性早期内皮祖细胞的培养方法 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2001231549A (ja) | 2000-02-28 | 2001-08-28 | Japan Science & Technology Corp | 不死化血管内皮細胞株 |
JP2003250820A (ja) | 2002-03-06 | 2003-09-09 | Toyoaki Murohara | 血管の再生方法、そのための細胞の分離回収方法及び装置 |
JP2007089536A (ja) | 2005-09-30 | 2007-04-12 | Tokai Univ | Notchリガンドを用いた血管内皮前駆細胞への分化誘導法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5980887A (en) * | 1996-11-08 | 1999-11-09 | St. Elizabeth's Medical Center Of Boston | Methods for enhancing angiogenesis with endothelial progenitor cells |
IL161903A0 (en) * | 2003-07-17 | 2005-11-20 | Gamida Cell Ltd | Ex vivo progenitor and stem cell expansion for usein the treatment of disease of endodermally- deri ved organs |
EP1621550A1 (en) * | 2004-07-29 | 2006-02-01 | Dompé S.P.A. | Tumor-homing cells engineered to produce tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) |
-
2008
- 2008-05-19 WO PCT/JP2008/001247 patent/WO2008142862A1/ja active Application Filing
- 2008-05-19 US US12/600,530 patent/US8491887B2/en not_active Expired - Fee Related
- 2008-05-19 EP EP08751765A patent/EP2163250B1/en not_active Not-in-force
- 2008-05-19 JP JP2009515092A patent/JP5339533B2/ja not_active Expired - Fee Related
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2001231549A (ja) | 2000-02-28 | 2001-08-28 | Japan Science & Technology Corp | 不死化血管内皮細胞株 |
JP2003250820A (ja) | 2002-03-06 | 2003-09-09 | Toyoaki Murohara | 血管の再生方法、そのための細胞の分離回収方法及び装置 |
JP2007089536A (ja) | 2005-09-30 | 2007-04-12 | Tokai Univ | Notchリガンドを用いた血管内皮前駆細胞への分化誘導法 |
Non-Patent Citations (11)
Title |
---|
ASAHARA T ET AL., EXPERIMENTAL MEDICINE, vol. 24, no. 1, 2006, pages 30 - 36 |
ASAHARA T ET AL., SCIENCE, vol. 275, 1997, pages 964 - 967 |
ASSMUS B ET AL., CIRCULATION, vol. 106, 2002, pages 3009 - 3017 |
II M ET AL., CIRCULATION RESEARCH, vol. 98, 2006, pages 697 - 704 |
II M ET AL., EXPERIMENTAL MEDICINE, vol. 24, no. 18, 2006, pages 2871 - 2879 |
KALKA C. ET AL.: "Endothelial progenitor cells: From bench to bedside", FUTURE CARDIOLOGY, vol. 2, no. 4, 2006, pages 455 - 466, XP008123606 * |
MIZUKAMI Y ET AL., NAT MED, vol. 11, 2005, pages 992 - 997 |
MUTA M ET AL., ONCOLOGY REPORT, vol. 10, 2003, pages 1765 - 1769 |
MUTA M. ET AL.: "Study of cancer gene therapy using IL-12-secreting endothelial progenitor cells in a rat solid tumor model", ONCOLOGY REPORTS, vol. 10, no. 6, 2003, pages 1765 - 1769, XP003024794 * |
OH H.K. ET AL.: "Tumor angiogenesis promoted by ex vivo differentiated endothelial progenitor cells is effectively inhibited by an angiogenesis inhibitor, TK1-2", CANCER RES., vol. 67, no. 10, 15 May 2007 (2007-05-15), pages 4851 - 4859, XP003024791 * |
See also references of EP2163250A4 |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010116665A1 (ja) * | 2009-04-07 | 2010-10-14 | 国立大学法人旭川医科大学 | 単核球由来の新規血管再生細胞群及びその分化誘導法 |
JPWO2010116665A1 (ja) * | 2009-04-07 | 2012-10-18 | 国立大学法人旭川医科大学 | 単核球由来の新規血管再生細胞群及びその分化誘導法 |
US8951795B2 (en) | 2009-04-07 | 2015-02-10 | National University Corporation Asahikawa Medical University | Revascularization cells derived from mononuclear cells, and method of inducing differentiation thereof |
JP5725509B2 (ja) * | 2009-04-07 | 2015-05-27 | 国立大学法人旭川医科大学 | 単核球由来の新規血管再生細胞群及びその分化誘導法 |
WO2012020566A1 (ja) | 2010-08-10 | 2012-02-16 | 国立大学法人旭川医科大学 | Ape1遺伝子導入による高機能化幹細胞・前駆細胞 |
Also Published As
Publication number | Publication date |
---|---|
EP2163250A4 (en) | 2011-01-19 |
JPWO2008142862A1 (ja) | 2010-08-05 |
EP2163250A1 (en) | 2010-03-17 |
US8491887B2 (en) | 2013-07-23 |
JP5339533B2 (ja) | 2013-11-13 |
US20100143311A1 (en) | 2010-06-10 |
EP2163250B1 (en) | 2013-01-09 |
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