WO2008120713A1 - 副交感神経活動亢進作用を有する医薬組成物又は飲食物 - Google Patents
副交感神経活動亢進作用を有する医薬組成物又は飲食物 Download PDFInfo
- Publication number
- WO2008120713A1 WO2008120713A1 PCT/JP2008/056076 JP2008056076W WO2008120713A1 WO 2008120713 A1 WO2008120713 A1 WO 2008120713A1 JP 2008056076 W JP2008056076 W JP 2008056076W WO 2008120713 A1 WO2008120713 A1 WO 2008120713A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- effect
- food
- drink
- medicinal composition
- actions
- Prior art date
Links
- 230000000694 effects Effects 0.000 title abstract 4
- 230000002708 enhancing effect Effects 0.000 title abstract 2
- 230000001734 parasympathetic effect Effects 0.000 title abstract 2
- 230000002567 autonomic effect Effects 0.000 abstract 3
- VOXXWSYKYCBWHO-QMMMGPOBSA-N (S)-3-phenyllactic acid Chemical compound OC(=O)[C@@H](O)CC1=CC=CC=C1 VOXXWSYKYCBWHO-QMMMGPOBSA-N 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/745—Bifidobacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/322—Foods, ingredients or supplements having a functional effect on health having an effect on the health of the nervous system or on mental function
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Ophthalmology & Optometry (AREA)
- Dermatology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Non-Alcoholic Beverages (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN200880011024XA CN101657192B (zh) | 2007-03-30 | 2008-03-28 | 具有副交感神经活动亢进作用的医药组合物或饮食物 |
US12/593,468 US8492442B2 (en) | 2007-03-30 | 2008-03-28 | Medicinal composition, food or drink having effect of enhancing parasympathetic nervous activity |
AU2008233633A AU2008233633B2 (en) | 2007-03-30 | 2008-03-28 | Medicinal composition, food or drink having effect of enhancing parasympathetic nervous activity |
JP2009507515A JP5770425B2 (ja) | 2007-03-30 | 2008-03-28 | 副交感神経活動亢進作用を有する医薬組成物又は飲食物 |
CA002682375A CA2682375A1 (en) | 2007-03-30 | 2008-03-28 | Medicinal composition, food or drink having effect of enhancing parasympathetic nervous activity |
EP08739194A EP2143427A1 (en) | 2007-03-30 | 2008-03-28 | Medicinal composition, food or drink having effect of enhancing parasympathetic nervous actions |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007-092528 | 2007-03-30 | ||
JP2007092528 | 2007-03-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2008120713A1 true WO2008120713A1 (ja) | 2008-10-09 |
Family
ID=39808293
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2008/056076 WO2008120713A1 (ja) | 2007-03-30 | 2008-03-28 | 副交感神経活動亢進作用を有する医薬組成物又は飲食物 |
Country Status (10)
Country | Link |
---|---|
US (1) | US8492442B2 (ja) |
EP (1) | EP2143427A1 (ja) |
JP (1) | JP5770425B2 (ja) |
KR (1) | KR20100016101A (ja) |
CN (1) | CN101657192B (ja) |
AU (1) | AU2008233633B2 (ja) |
CA (1) | CA2682375A1 (ja) |
SG (1) | SG182959A1 (ja) |
TW (1) | TWI504392B (ja) |
WO (1) | WO2008120713A1 (ja) |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2012017282A (ja) * | 2010-07-07 | 2012-01-26 | Calpis Co Ltd | 迷走神経活性化剤 |
WO2013129085A1 (ja) * | 2012-03-02 | 2013-09-06 | 独立行政法人産業技術総合研究所 | 概日リズム改善剤 |
JP2013224287A (ja) * | 2012-03-19 | 2013-10-31 | Sapporo Breweries Ltd | セロトニン分泌促進剤 |
CN105274023A (zh) * | 2015-09-30 | 2016-01-27 | 厦门和美科盛生物技术有限公司 | 植物乳杆菌L.plantarum HM6055及其用途 |
WO2016032000A1 (ja) * | 2014-08-29 | 2016-03-03 | わかもと製薬株式会社 | 乳酸菌含有組成物 |
JP2016108303A (ja) * | 2014-12-10 | 2016-06-20 | 国立大学法人岐阜大学 | 神経機能改善剤 |
JPWO2021111980A1 (ja) * | 2019-12-02 | 2021-06-10 | ||
WO2021117857A1 (ja) * | 2019-12-13 | 2021-06-17 | 株式会社明治 | 心拍数低下用組成物 |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPWO2008120712A1 (ja) * | 2007-03-30 | 2010-07-15 | サントリーホールディングス株式会社 | 交感神経活動亢進作用を有する医薬組成物又は飲食物 |
CN108624533B (zh) * | 2018-05-10 | 2021-03-09 | 浙江工商大学 | 一种植物乳杆菌中分离纯化苯基乳酸的方法 |
TWI754126B (zh) * | 2018-07-19 | 2022-02-01 | 大江生醫股份有限公司 | 益生質組合物用於改善女性陰道內的菌相的用途及外用衛生用品 |
JP7369992B2 (ja) * | 2019-05-13 | 2023-10-27 | 株式会社明治 | 自律神経機能改善用の発酵乳 |
KR102317304B1 (ko) * | 2019-05-14 | 2021-10-26 | 한국식품연구원 | 락토바실러스 아시도필루스를 포함하는 갱년기 여성의 신경과민, 개미환각, 불면증, 현기증, 또는 피로의 예방, 개선, 또는 치료용 조성물 |
JP7072965B2 (ja) * | 2019-12-02 | 2022-05-23 | 株式会社ライフ・クオリティ研究所 | ストレス障害の予防又は改善用剤及びそれを含む組成物 |
KR102201544B1 (ko) * | 2020-04-20 | 2021-01-12 | 주식회사 휴온스내츄럴 | 페닐락틱산을 생산하는 페디오코쿠스 에시디락티시 hbt 균주 및 이를 배양한 페닐락티산의 생산방법 |
Citations (10)
Publication number | Priority date | Publication date | Assignee | Title |
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JPH04352720A (ja) * | 1991-05-30 | 1992-12-07 | Tanabe Seiyaku Co Ltd | 癌患者用アミノ酸製剤 |
JPH1045610A (ja) * | 1996-08-07 | 1998-02-17 | Karupisu Kk | 抗ストレス剤及び抗ストレス作用を有する機能性食品 |
JPH10502944A (ja) * | 1995-10-27 | 1998-03-17 | メディシス ファーマシューティカル コーポレイション | 皮膚科的疾患の処理のための組成物類及びそれらの使用方法 |
JPH10139674A (ja) * | 1996-11-11 | 1998-05-26 | Yakult Honsha Co Ltd | インターロイキン12産生促進剤 |
JPH11209294A (ja) | 1998-01-20 | 1999-08-03 | Karita Takahisa | 精油を有効成分とする副交感神経作用剤 |
JP2000300284A (ja) | 1999-04-20 | 2000-10-31 | Seibutsu Kassei Kenkyusho:Kk | 乳酸菌を用いて作られたフェニル乳酸およびその生産方法 |
JP2004067537A (ja) | 2002-08-02 | 2004-03-04 | Asahi Kasei Chemicals Corp | 交感神経の興奮抑制剤 |
JP2004510740A (ja) * | 2000-10-06 | 2004-04-08 | ソシエテ デ プロデュイ ネスレ ソシエテ アノニム | 皮膚の免疫系のバランスを保つためのプロバイオティック乳酸菌の使用 |
JP2004131436A (ja) | 2002-10-11 | 2004-04-30 | Kanebo Ltd | 香料組成物 |
JP2005272445A (ja) | 2004-02-27 | 2005-10-06 | Fuso Pharmaceutical Industries Ltd | 涙液分泌促進ペプチドおよびその組成物 |
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JPH092959A (ja) | 1995-06-16 | 1997-01-07 | Yakult Honsha Co Ltd | IgE抗体産生抑制剤および抗アレルギー剤 |
TW200804591A (en) * | 2005-10-31 | 2008-01-16 | Suntory Ltd | Lactic acid bacterium having immunoregulatory activity derived from moromi for wine fermentation |
-
2008
- 2008-03-28 US US12/593,468 patent/US8492442B2/en active Active
- 2008-03-28 KR KR1020097022792A patent/KR20100016101A/ko not_active Application Discontinuation
- 2008-03-28 CA CA002682375A patent/CA2682375A1/en not_active Abandoned
- 2008-03-28 CN CN200880011024XA patent/CN101657192B/zh active Active
- 2008-03-28 TW TW097111617A patent/TWI504392B/zh active
- 2008-03-28 EP EP08739194A patent/EP2143427A1/en not_active Withdrawn
- 2008-03-28 WO PCT/JP2008/056076 patent/WO2008120713A1/ja active Application Filing
- 2008-03-28 AU AU2008233633A patent/AU2008233633B2/en not_active Ceased
- 2008-03-28 SG SG2012047569A patent/SG182959A1/en unknown
- 2008-03-28 JP JP2009507515A patent/JP5770425B2/ja active Active
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JPH04352720A (ja) * | 1991-05-30 | 1992-12-07 | Tanabe Seiyaku Co Ltd | 癌患者用アミノ酸製剤 |
JPH10502944A (ja) * | 1995-10-27 | 1998-03-17 | メディシス ファーマシューティカル コーポレイション | 皮膚科的疾患の処理のための組成物類及びそれらの使用方法 |
JPH1045610A (ja) * | 1996-08-07 | 1998-02-17 | Karupisu Kk | 抗ストレス剤及び抗ストレス作用を有する機能性食品 |
JPH10139674A (ja) * | 1996-11-11 | 1998-05-26 | Yakult Honsha Co Ltd | インターロイキン12産生促進剤 |
JPH11209294A (ja) | 1998-01-20 | 1999-08-03 | Karita Takahisa | 精油を有効成分とする副交感神経作用剤 |
JP2000300284A (ja) | 1999-04-20 | 2000-10-31 | Seibutsu Kassei Kenkyusho:Kk | 乳酸菌を用いて作られたフェニル乳酸およびその生産方法 |
JP2004510740A (ja) * | 2000-10-06 | 2004-04-08 | ソシエテ デ プロデュイ ネスレ ソシエテ アノニム | 皮膚の免疫系のバランスを保つためのプロバイオティック乳酸菌の使用 |
JP2004067537A (ja) | 2002-08-02 | 2004-03-04 | Asahi Kasei Chemicals Corp | 交感神経の興奮抑制剤 |
JP2004131436A (ja) | 2002-10-11 | 2004-04-30 | Kanebo Ltd | 香料組成物 |
JP2005272445A (ja) | 2004-02-27 | 2005-10-06 | Fuso Pharmaceutical Industries Ltd | 涙液分泌促進ペプチドおよびその組成物 |
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VALERIO F. ET AL.: "Production of phenyllactic acid by lactic bacteria: an approach to the selection of strains contributing to food quality and preservation", FEMS MICROBIOL. LETT., vol. 233, no. 2, 2004, pages 289 - 295, XP008120877 * |
Cited By (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2012017282A (ja) * | 2010-07-07 | 2012-01-26 | Calpis Co Ltd | 迷走神経活性化剤 |
US10695383B2 (en) | 2012-03-02 | 2020-06-30 | National Institute Of Advanced Industrial Science And Technology | Circadian rhythm-improving agent |
WO2013129085A1 (ja) * | 2012-03-02 | 2013-09-06 | 独立行政法人産業技術総合研究所 | 概日リズム改善剤 |
JP2013181005A (ja) * | 2012-03-02 | 2013-09-12 | National Institute Of Advanced Industrial Science & Technology | 概日リズム改善剤 |
JP2013224287A (ja) * | 2012-03-19 | 2013-10-31 | Sapporo Breweries Ltd | セロトニン分泌促進剤 |
JP2017061567A (ja) * | 2012-03-19 | 2017-03-30 | サッポロホールディングス株式会社 | セロトニン分泌促進剤 |
WO2016032000A1 (ja) * | 2014-08-29 | 2016-03-03 | わかもと製薬株式会社 | 乳酸菌含有組成物 |
JPWO2016032000A1 (ja) * | 2014-08-29 | 2017-07-13 | わかもと製薬株式会社 | 乳酸菌含有組成物 |
JP2016108303A (ja) * | 2014-12-10 | 2016-06-20 | 国立大学法人岐阜大学 | 神経機能改善剤 |
CN105274023A (zh) * | 2015-09-30 | 2016-01-27 | 厦门和美科盛生物技术有限公司 | 植物乳杆菌L.plantarum HM6055及其用途 |
JPWO2021111980A1 (ja) * | 2019-12-02 | 2021-06-10 | ||
WO2021111980A1 (ja) * | 2019-12-02 | 2021-06-10 | 株式会社ライフ・クオリティ研究所 | 起立性低血圧の予防又は改善用剤及びそれを含む組成物 |
JP7063514B2 (ja) | 2019-12-02 | 2022-05-09 | 株式会社ライフ・クオリティ研究所 | 起立性低血圧の予防又は改善用剤及びそれを含む組成物 |
CN114786693A (zh) * | 2019-12-02 | 2022-07-22 | 生活质量研究所 | 直立性低血压的预防或改善用剂和包含其的组合物 |
WO2021117857A1 (ja) * | 2019-12-13 | 2021-06-17 | 株式会社明治 | 心拍数低下用組成物 |
Also Published As
Publication number | Publication date |
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AU2008233633B2 (en) | 2013-11-14 |
US20100150891A1 (en) | 2010-06-17 |
EP2143427A1 (en) | 2010-01-13 |
CN101657192A (zh) | 2010-02-24 |
JP5770425B2 (ja) | 2015-08-26 |
KR20100016101A (ko) | 2010-02-12 |
CN101657192B (zh) | 2013-01-23 |
US8492442B2 (en) | 2013-07-23 |
TW200906385A (en) | 2009-02-16 |
CA2682375A1 (en) | 2008-10-09 |
AU2008233633A1 (en) | 2008-10-09 |
JPWO2008120713A1 (ja) | 2010-07-15 |
TWI504392B (zh) | 2015-10-21 |
SG182959A1 (en) | 2012-08-30 |
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