WO2007066832A1 - Composition emulsifiee - Google Patents

Composition emulsifiee Download PDF

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Publication number
WO2007066832A1
WO2007066832A1 PCT/JP2006/325115 JP2006325115W WO2007066832A1 WO 2007066832 A1 WO2007066832 A1 WO 2007066832A1 JP 2006325115 W JP2006325115 W JP 2006325115W WO 2007066832 A1 WO2007066832 A1 WO 2007066832A1
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WO
WIPO (PCT)
Prior art keywords
asbin
steer
compound
substance
water
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Application number
PCT/JP2006/325115
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English (en)
Japanese (ja)
Inventor
Shinobu Ito
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Ito Co., Ltd.
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Filing date
Publication date
Application filed by Ito Co., Ltd. filed Critical Ito Co., Ltd.
Publication of WO2007066832A1 publication Critical patent/WO2007066832A1/fr

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04Dispersions; Emulsions
    • A61K8/06Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/676Ascorbic acid, i.e. vitamin C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52Stabilizers
    • A61K2800/522Antioxidants; Radical scavengers

Definitions

  • Emulsifying agent with surface force lowering effect consisting of its conductor, stock, and material medium, which has good stability and high safety.
  • German DE 9 8 4 6 6 60 discloses oxides or oxides containing chemicals captured by organic silicon shared by oxides. Useful because the compound is used during pouring.
  • Ming X is cooked, dissolved and dispersed in it, and has good stability and high stability. Providing a child containing a compound when the agent in the small amount is decomposed To provide.
  • Emulsions with good stability and high safety can be prepared by making a solvent in the form of an aqueous solvent using a raw material composed of a mixture of more than one kind of substance and a mixture of more than one kind of substance. I found this and completed the Ming. Of Ming
  • Gusen X is a mixture of more than one species of the chemical compound, a compound of one or more species of the chemical substance having a surface-activity-reducing action that is dissolved and dispersed in it, and a compound of one or more species of the chemical substance.
  • the stability of the emulsified product can be improved by forming the child in an aqueous solvent from the raw material made of the compound, and the stability and the safety can be improved.
  • Clearly usable chemical substances with surface force-reducing action are those that have a positive surface force-decreasing action when evaluated by the following force-reducing action.
  • the substance having a surface force difference with a comparison ratio of 0 at the time of 20 c and a humidity of 50 is positive for the force reduction effect of the present invention.
  • Xanthine In the xanthine oxida (X XOD) system, Soxy (2), which is a species of active oxygen, is generated in 0 (ww) hee, and 5 5 e P oe N de (D PO) and measured by ES. , The quality of gangan (O) was used as the standard, and the sigma ratio of the sump was obtained and compared with the additive. It was confirmed that it had a supra-oxidative activity above 0 in comparison with the signal strength of the added nuclei, and the substance was confirmed to have a chemical action. 2, a species of active oxygen by reaction
  • the substance that has been confirmed to have a sex has a chemical action.
  • examples of chemical substances with surface-activity reducing effect that can be clearly used are shown below, but the invention is not limited thereto.
  • a substance in which the chemical compound having a force-reducing action is one or more compound compounds selected from the compounds shown in (() below, or a salt thereof.
  • the upper one of the deviations of RR, R, and R represents the higher grade. It has 8 to 22 carbon atoms, and more preferably N, Sutin, Chin, Styrene, Furo, No, Chi, In, 2 decane, Isosoteane, Chin, 2 Decanoic acid. Item 3 is characterized by the fact that it is the residue of the above.
  • a A is good, but A A is preferable, but D A A can be used in industrial applications.
  • R 1 and R 2 are methyl or hydrogen, R 1 is a group of an inorganic or organic acid, or is an aldehyde group, and preferably R 4 is a water-soluble ster group. More preferably, the water-soluble starch is A ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,.,,.
  • F which is of the case of (n)
  • D-form or D-form can be used in the desired applications.
  • Float which is a case of (n) can be used for each type type v type type.
  • R is selected from the group consisting of chi, in, astaxanthin, xanthine and cupuxanthin
  • R 2 is the inorganic or organic acid ester or the adduct group
  • R 2 is preferably water. It is a soluble steric group, more preferably the water-soluble steric group is It is a soluble organic acid ester of lactic acid, lactic acid, bivin, and a.
  • R thiocyanic acid and amides can be used in the form of s-, s-, s-, and s-types.
  • a mixture of one or more compounds having a chemical-reducing action is selected from the compounds below.
  • the AA that can be used for this purpose is preferably the D-form, and the flo, le, and Y-form can be used for chino, in-acid, and ide. It is possible to use the offset type.
  • salts of chemicals with surface-activity-reducing action such as Sim, Nam, Mu, Am iron, Hydrochloride, Genus, Inorganic acids, etc. This it can.
  • Ming-no-Ku is a multi-valent gose, a tanop, an isoprono, a drug, a xenanthine, an a, a monseroin, an oleia, a monooingo, an oin.
  • Gusero Oin Gusero, Chin, 2 Zincabon, Sinapine (35 x 4), 2, 5 xyl benzoic acid 5 x, Shear 4 ky, 3 in, Diata, 2 (4 x 4) ) Disperse benzoic acid, earthworm, 5 (phomethy) and the like can be mentioned.
  • This includes, for example, prop, zip, pop, gus, zip, pos, ping, zip, pos, 1, 3 nzio, Examples include chi, square, callus, su, kiss, and loss. These can be used alone or in combination of two or more.
  • the water used in Ming is not limited to ions of p to 3, ions, natural aka ions, acidic electrolytic ions, inus ions, strong, strong aka.
  • Possessive structures include, for example, Zafactin namuo and its compounds, or their aons, cations, nonionics, and sexes, but in the following, the following can be used.
  • bodies that can be clearly used include fats such as gum, stinkaum and the like; "Achste such as namu, taan, lammom; snum, lares", Tanoa and the like.
  • A Ag, Na, Demp conductor, Lagan gum, Aquaqua polymer
  • Examples include, but are not limited to, more than 12 interfaces of molecular agents.
  • Fluoro conductors such as rho (ta E) and fluorine; BBA; gallic acid conductors such as propionic acid propi- ate; vitamin C (AA) and / or its conductors; Phosphoric acid and its conductors; sulfites such as sodium sulfate; hydrogen sulfites such as hydrogen sulfate; thiosalts such as thiona; hydrogen sulfate; hydrogen, hypo, oxello, thio, ogu, and cysteinate. Can be done.
  • anti-vitamins such as og, cysteine, cysteine, ides, glutathione, cysteine, cenbitan A, nzyme Q 0, humpo, po, catechins LAA tedecane, fluoro, etc. And its conductors.
  • hydrocarbons are higher-grade esters, higher-grade esters, gussets, phosphorus, higher-grade species, higher-grade plants and animals, sterosters, sterosters, sterosters, pods, and funnels. , But not limited to them, and safety is ensured when organisms come into contact with it. .
  • the temperature at 40 ° C is lower than that at 60 ° C.
  • qualities that can be used in light are: N, Sutin, Chi, Stearn, Isosteain, Indecin, 2 Kistane, Oin Oin, Noin, Dosaxane, Ipenta, I Soxadecane, Anteisant, Dye, Hydrogen Eyes and their A, Cu, Gne, Calcium soaps, Adducts and other conductors; Raffins (, Raoi), Fluid fins, Fluid raffins, Carbonization of fin-o, poten, poten, poten, squann, obscuran squan stain, etc .; cadwa wax cana wax, issucus, miro montan wax, ozo Waxes such as rye, stiin, finwax, equine wax, petrotum, fisherlo wax, tin wax, tin propinpo Palms; palm, mumm s
  • Te instear chino steer, astaxanthin, teinpi, carote, carotene, fu, tofu, fu, gushinfuro, metigsif, quin, nzyme, nera ,.
  • There are some natural oysters such as wow, woodpecker, gupdo, cutlet, amod, rice, onion, pico, zym A, ice, a, Ass, asgas ,, atchia, and, ate, aka, a
  • a metal or metal oxide as a light-active substance, in which the following substances or metal oxide particles containing a metal oxide are dispersed in the above-mentioned substance in an amount of 0 to 95. it can.
  • the metals and metal oxides that can be used at this time are suitable for manufacturing ink jet inks, for example. Narrow diameter compounds such as deer and anatase can be selected. Furthermore, finely ground metal particles, such as ferrous iron and am-gold, can also be selected for the appropriate application.
  • Particularly preferred pigments for use as a light-active substance are Gummud 122, C Guny 4 C Gummube 1. , Especially when used for color.
  • the amount of material contained in is usually 0 0 for. More preferably, the amount of pigment is in the range 0-2.
  • the transparent substance It is also possible to use a substance or a polymer decomposing substance as the transparent substance, and a polymer carbon is preferable. If the salt is sodium or thallium boric acid, or an ammonium salt.
  • the molecular decomposition is performed, for example, high molecular weight ax, high molecular weight aus, high molecular weight abundance, bone, sodium salt, salt of a salt and axon on, 4 ammonium, black
  • the amount of molecular decomposition is 0 0 5 0, preferably 0 to 3 with respect to.
  • the preferable content of or in liquid is 0 to 99 99 relative to the composition amount, and 0 0 9 9 is preferable.
  • the soluble substance of [ is not particularly limited, and is preferably a substance having the above-mentioned chemical action.
  • the preferred content of the water-soluble substance and the water-soluble substance in Ming is 50 to 95, which is about 9 to 9 9 relative to the composition.
  • the amount of the compound that has the effect of reducing the force of light is preferably 0 000 to 45 and more preferably 0 to 20 with respect to the composition amount. It is not preferable because 0/0, which also has a force-reducing action, can produce a child that exhibits a sufficient anti-reaction action, and that it can have a viscosity of more than 45 to be used.
  • the 23 substances of light are preferably 10 to 0 G or striated, or preferred.
  • the qualitativeness of the claim 2 is kept good under 00 m, preferably with an average in the range of 0 m to 30 n.
  • Ming is pharmaceuticals, pharmaceuticals, cosmetics, cosmetics, external ionic compositions, vibrational compositions, electromagnetic compositions, thermal compositions, electrolytic compositions, foods, foods, functional foods, foods, feeds, aging, oxidation, and antioxidants. It only needs to be one or more compounds selected from.
  • pharmaceuticals, pharmaceuticals, cosmetics, cosmetics, external use ionic composition, vibrational composition, electromagnetic composition, thermal composition, electrolytic composition, food, food functional food, food, feed, aging, antioxidant are selected.
  • ionic composition vibrational composition
  • electromagnetic composition thermal composition
  • electrolytic composition thermal composition
  • food functional food food functional food
  • electrolytic composition food, food functional food, food, feed, aging, antioxidant
  • This 100 can also be prescribed as the final drug of that of claim 2. It is recommended that the dosage of the preparation be 0. 0 to 50 in quantity. If it is applied to the skin of body 2 at this time, the skin is c 0 .0 m 0, and if it is administered by oral administration or the like, the body weight is 60 k or 0 .0 m to 1. At least one selected from pharmaceuticals, pharmaceuticals, cosmetics, cosmetics, external ionic composition, vibrational composition, electromagnetic composition, thermal composition, electrolytic composition, foods, foods, functional foods, foods, feeds, aging oxidation, and antioxidants. The following can be theoretically accepted.
  • Emulsion can also be prepared by compounding with an agent of the following state in accordance with the conventional method of Ming.
  • Emulsion, Cum, Powder, Dispersion, Multi-layer, S, Ge, Solid, Powder, Pet, Emulsion can be selected.
  • a conventional method of the present invention it can be prepared by compounding with an agent in a state known as an external composition.
  • an agent in a state known as an external composition.
  • It can be used as cosmetics, dispersion chemicals, etc., and can be selected from multi-layered emulsion, soot, gel, solid form, powder.
  • ingredients used in various agents namely (hot spring water, deep layer), oil agents, metal salts, agents, powders, water-soluble molecules, etc.
  • Film Fat, inclusion, protection, antibacterial, fragrance, deodorant salts, P, refreshing, animals / biological products, plant products, vitamins, nucleic acids, hormones, cells, blood stimulants, harvesting , Anti-reactive oxygen keratolytic,
  • Examples of the above-mentioned substances that can be added to the cosmetics are natural or synthetic, and whether they are solid, semi-solid or solid, It is possible to use hydrocarbons, corpuscles, types, higher grades of stainless steel, foot, and slip.
  • the oil agent that can be used obviously, the oil agent described in Japanese Patent No. 2044-5 can be used.
  • Aeon cations there are aeon cations, non-ionics and cations, but in Akira, ionics can be used. Can be added to
  • This component includes, for example, hydrocarbons, stes, glycerides, higher grades, polyvalent grades, lower grades, nonionic anions, and amphoterics.
  • Examples include ultraviolet rays, oxidation, oxidization agents, solubilizing agents, antiseptic agents, preservatives, sterilizing agents, pigments, fragrances, powders, and water.
  • the distribution range it is preferable to use a device for adding a cleavage shape when the emulsifier is placed under 200 m. More preferably, it is possible to produce 000 m-sized particles dispersed in water and water-based agents in the form of a small amount of 15 s. As for the flow of the constant power, the power of the specially required tap water is sufficient. Or, it is possible to mix the water stored in the tank as usual.
  • Examples of the device for adding a shape include ,, a mixer, a mixer, a mixer, etc., but it is preferable to use a static mixer, a jig dis- gector, and a cupro-phytochemical quantifier a. It is also possible to use at least one kind of arrangement from the group consisting of O.
  • a jetterget etd sperga or) that dissipates the onion in a small volume in the nose can be used.
  • Other suitable arrangements include the Croporus fitter, the Ikuposugarasufita, and the cro d zer ao G a Naiza Noz.
  • a zip detector is the preferred device.
  • ddd is at least 20 and preferably 3 less than the value obtained by the above-mentioned method without force. This is done after the phase inversion is completed.
  • Jeddy targets have a size where the available money is dissipated in a small volume that is available in the dispersion range, which is used to obtain highs.
  • SX Swiss Noduit
  • the static mixer is thereby operated in a manner similar to that of a jitter detector, ie the available energy is available in the static mixer.
  • 0 5 to 50 are relatively simple and expensive It can be generated by a pump.
  • the (control) is high, with at least 100 S preferred from 00 to 2000000 s, and most preferred from 35,000 to 500000. It depends on this pressure drop. [Below, the implementation will be described in more detail, but is not limited to these implementations. It should be noted that the following gussets were used with a content of over 9 8.
  • AF Surfactin Na
  • AF Surfactin Na
  • VE NaNro; O
  • VCP AsA Tera; Ke
  • TDG Tung Thin :
  • the composition was created.
  • Inteinte Insteer, Tisteer, Astaxanthintein, Pinrotintin, Fro-P-Floin-Methin-Sin-Flo, Met-In-Sin-Flo, Kinin, Nzyme A, Non, Nine, Liquid Fi Squan, Chin Sopropy, Sutin Sopropy, Sutin, Ste Iso, Sutin Octasi, Sutin Octide Desi, Nera Liquid Fin Isostea Steste 2 Til Xan Guse, 2 Xan, Hiwa, Op, Azalea, Gupshid, Kanut, Ammond Rice , Octamethylene siloxane, methite siloxane, typosiloxane, octametyl cycloteroxane, pic, Nzyme A, methicyl pentapentane xanthate siloxane siloxane, methicyl cyclosiloxane, methypochloroxane, meth Fup
  • a sex mixture 6 ghen 4 APP 2 and sex mixture were mixed in the lower direction.
  • AA chin AsA 2-6 te, AA 2 6 te, AA te, AA 6 te AsA 6 steer chino, i, chinotate, inte, inte, in panoramice, chisteer, astaxanthin, teinpi, Kachin Carotene, Fu, Furo, Tofu, Methyg cinph, Metigu cinnph, Kin, Nzyme A, No 0 were mixed and squalene was added to 0.
  • step A the safactin name was dissolved in the ginseng, while the following substances were added in small amounts to prepare.
  • VEP TD Surfactin sodium 0 2.
  • AA Chin, AA 2-6, AA-te, AA 26-6 AA 6 steer Flo, p-Flo Y-Flo, Methyl Glucin-Flokin, Nzyme A, and No-Chinote 0 0 Mix and add squalane to 00.
  • the cosmetics that were manufactured were re-introduced, and an accelerated test at 40 ° C was conducted, and the color was checked for a while.
  • step A the safactin name was dissolved in the guss while adding a small amount of the following substances to prepare the ingredients.
  • TE AA TE AA 26 TE
  • 6 steer TE, IN, TE, INTE, INTEIN Steer, Chisteer Astaxanthin, Tain, Pin 6 Carotene Carotene, Flo, F, Y-Flo, Met-Syn-Flo, Met-Synthoff, Kin, Nzyme A, o In addition, it was 0.
  • Each dispersion was measured to have a static mixer of 2 34 m, a jitter detector of 27 m, a cuposcope of 20 m, and an extract of 94 m a o G a 1 Naiza Noz 5 3 m.
  • Dispersion A was used to dissolve the safactin sodium in the gusset, while adding a small amount of the substance below to prepare.
  • Ink ink non-ink ink photographic film
  • optical particles When optical particles are added by 0 5, they can be extended to 3 times as long as the original of each product, and the resolution is stable due to the fineness of the elementary particles. It could be a pigment particle containing a chemical substance.
  • VEP 0 Surfactin name 0. The following are sex mixtures: Mix 0 n 5 fluoro and add acid to 0 to mix.
  • B A 2, Steen 0 5, and A were added to 8 ports, and the dissolved B solution was added to 80 ports, and a mixer 5000 P, 5 was added.
  • the temperature was 34 bnm. This is used as a magnetic material for pharmaceuticals, cosmetics, vibration composition, electromagnetic composition, thermal composition, electrolytic composition, materials, ink, ink ink, and sexual memory. It was confirmed that it was possible to create a memory or a memory with a high degree of stability.
  • [0 2 0 dispersion] was prepared by adding APPS to the A-cell and adding a small amount of the following substances.
  • Sen was added to the mixture containing the following quality while adding 0 PP to 0. It was a combination of AA Tell, LA A, AA Pi AA LA A pliers, LAsA 2 te AsA 2 te, AsA 2 steer, AsA 2 steer AA 6 te, AA 6 te, LA A 6 steer, AA 6 Isosteer, AA 2, 6 dite AsA 2, 6 te AA 2, 6 steer AsA 26 steer, AA 2 good 6 te AsA 2 6 te, AsA 2 good 6 steer, AsA 2 good 6 steer, AsA 2 good 6 steer, AsA 2 good 6 steer, AsA 2 good 6 ft, AsA 2 6 te, AA 2 6 te, AsA 2 6 Steer, AA 2 6 Steer, AsA 2 6 Fu AA 2 Rain 6 Te, AsA 2 I 6 Iso Te, AsA 2 In 6 Steer AsA 2 I
  • compositions for this and other purposes
  • Pharmaceuticals cosmetics Cosmetics, foods Foods for external use, ionic composition vibrational composition, electromagnetic composition thermal composition, electrolytic composition functional food, aging whitening, pigmentation goodness, second treatment Good for rough skin, good for oil, good for dry, good for small pores, for treatment of blush, for treatment of hair loss, for growth, burns, for skin burns, for skin problems, for 78 people 2 times a day. 5 CC) was applied to the affected area and was applied externally for 60 minutes. Ion, vibration, electromagnetic, thermoelectrolysis The commercially available product was used.
  • Clearly usable chemical substances having a surface force-reducing action can be evaluated by the following force-reducing action, as long as the surface-reducing action is positive. If the above two tests under the force-reducing action are positive, the usable surface-reducing action is judged to be positive. , Pour water into a tank with a diameter of 20 and drop oil on the surface of the water to float the oil in a circular shape so that the oil has a small diameter. Next is the degree of purification.
  • Xanthixanthine oxidase which is a species of active oxygen, is a species of active oxygen (2 ⁇ ).
  • the quality of gun (O) was used as the standard, and the GUN ratio of the supplement was calculated and compared with the addition. It was confirmed that the substance had a higher level of sulfurity than that of the gut level of the added substance, and the substance that has been confirmed to have the chemical action was regarded as the selenium compound. 2.
  • Generated (.O) which is a species of active oxygen, in 0 (ww) heat by photometry, supplemented with 5 5 eoexde (D PO) with addition of a quantity of saturation, and measured by ESR did. Then, the Gna ratio of the supplement was calculated based on the signa of gangan (O), which is the internal quality, and the additive was compared. It was confirmed that the substance had a property above 0 in comparison with the gnosis degree of the added substance, and the substance that has been identified has a chemical action.
  • a unit of more than a species of gas or liquid is a compound thereof, and a unit of a plurality of a substance of a dissolved or dispersed compound having a surface force lowering action is a compound thereof. It is possible to provide an emulsifier with good stability and high safety by forming the child with an aqueous solvent from raw materials composed of more than one kind of organic substance.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Dispersion Chemistry (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cosmetics (AREA)
  • Fodder In General (AREA)
  • Medicinal Preparation (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)

Abstract

Le problème à résoudre dans le cadre de la présente invention consiste à fournir des particules émulsifiées constituées d’un antioxydant présentant un effet d’abaissement de la tension superficielle ou d’un dérivé de celui-ci, d’une matrice liquide, d’une substance liposoluble et d’un solvant et présentant une stabilité et une sécurité excellentes, ainsi que des utilisations desdites particules et un procédé de production de celles-ci. La solution proposée consiste à produire des particules émulsifiées présentant une excellente stabilité et une haute sécurité dans de l’eau ou un solvant liquide à partir d’une matière première constituée de glycérine et/ou d’au moins une matrice liquide simple ou d’un complexe de celles-ci, d’au moins un antioxydant simple présentant un effet d’abaissement de la tension superficielle ou d’un complexe de ceux-ci dissout ou dispersé dans celle-ci et d’au moins une substance liposoluble ou un complexe de ceux-ci. La présente invention concerne également des utilisations desdites particules et un procédé pour leur fabrication.
PCT/JP2006/325115 2005-12-09 2006-12-06 Composition emulsifiee WO2007066832A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2005380887A JP4866607B2 (ja) 2005-12-09 2005-12-09 乳化組成物
JP2005-380887 2005-12-09

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WO2007066832A1 true WO2007066832A1 (fr) 2007-06-14

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