WO2007066832A1

WO2007066832A1 - Emulsified composition

Info

Publication number: WO2007066832A1
Application number: PCT/JP2006/325115
Authority: WO
Inventors: Shinobu Ito
Original assignee: Ito Co., Ltd.
Priority date: 2005-12-09
Filing date: 2006-12-06
Publication date: 2007-06-14
Also published as: JP2007160287A; JP4866607B2

Abstract

[PROBLEMS] To provide emulsified particles which are constituted of an antioxidant having a surface tension lowering effect or a derivative thereof, a liquid matrix, a fat-soluble substance, and a solvent and which are excellent in stability and safety; uses of the same; and a process for production thereof. [MEANS FOR SOLVING PROBLEMS] Emulsified particles having excellent stability and high safety can be produced in water or a liquid solvent from a raw material consisting of glycerol and/or at least one simple liquid matrix or a complex thereof, at least one simple antioxidant having a surface tension lowering effect or a complex thereof which is dissolved or dispersed therein, and at least one simple fat-soluble substance or a complex thereof. The invention also provides uses of the particles and a process for production thereof.

Description

[

[Technology]

Emulsifying agent with surface force lowering effect, consisting of its conductor, stock, and material medium, which has good stability and high safety.

(

[]

From the past, as a method for obtaining microparticles, a method of blending an organic silicic acid and a method of blending a metal are known.

[Germany DE 9 8 4 6 6 60 discloses oxides or oxides containing chemicals captured by organic silicon shared by oxides. Useful because the compound is used during pouring.

] Germany DE 9 8 46 6 60

0 004 DE 9 8 4 6 6 5 9 teaches the use of axoxyaxisilanes to make particles containing chemical compounds with reactive actinic groups.

[2 Germany 8466 5 9

[However, in the method of blending organic silicic acid, a large amount of these components needs to be blended in order to obtain, and there are problems such as poor extension and low safety. In addition, the emulsion was fragile and the stability was not sufficient. As mentioned above, the conventional composition was not satisfactory enough. In addition, it is difficult for these particles to diffuse into the layer that collects easily, and it is necessary to re-disperse or re-solve them to use them as raw materials, and in addition, they are rough and handled as chemical substances. There was a problem that the performance of particles containing was not fully utilized. In particular, when the particles contain an antioxidant, the smaller the particles, the more susceptible they are to the deterioration of the element. There were problems such as sinking, sinking, and separation.

[

[Problems to be solved by Ming] Ming X is cooked, dissolved and dispersed in it, and has good stability and high stability. Providing a child containing a compound when the agent in the small amount is decomposed To provide.

007)

(Ming

[Problems to be solved by clarification Good stability and high safety Stable inclusion of anti-oxidants in the child is possible. Drugs, pharmaceuticals, cosmetics cosmetics, external ionic composition Vibration composition, electromagnetic composition It is an object of the present invention to provide a thermal composition, an electrolytic composition, a food, a food, a functional food, a food, a feed, and a child composition containing a chemical substance suitable for an aging antioxidant, and how to use the composition.

008

As a result of repeated discussions to solve the above-mentioned problems, as a result, it was found that guxen x is a mixture of more than one species of the cook, and that it has a dissolved and dispersed surface force lowering effect. Emulsions with good stability and high safety can be prepared by making a solvent in the form of an aqueous solvent using a raw material composed of a mixture of more than one kind of substance and a mixture of more than one kind of substance. I found this and completed the Ming. Of Ming

Gusen X is a mixture of more than one species of the chemical compound, a compound of one or more species of the chemical substance having a surface-activity-reducing action that is dissolved and dispersed in it, and a compound of one or more species of the chemical substance. The stability of the emulsified product can be improved by forming the child in an aqueous solvent from the raw material made of the compound, and the stability and the safety can be improved.

The details of the present invention will be explained in detail below.

Clearly usable chemical substances with surface force-reducing action are those that have a positive surface force-decreasing action when evaluated by the following force-reducing action.

[] Force-reducing effect; One of the two tests below is positive, and the surface-reducing effect that can be clearly used is determined to be positive. , Pour water into a tank with a diameter of 20 and drip oil on the surface of the water to float the oil in a circular shape on the surface of the water to a diameter. Then test the quality of the oil with a degree of refinement.

This is the case when it was observed that a circular oil was dispersed in the center of the tank at 0 c and a humidity of 50 and spread to the surface of the tank. 2 Kyowa Gakusha dynamometer (c.

When the force of the chemical substance is measured using Bvp A), the substance having a surface force difference with a comparison ratio of 0 at the time of 20 c and a humidity of 50 is positive for the force reduction effect of the present invention. [

Clearly usable chemical substances with surface-reducing action were substances having the ability to eliminate fuji by one test by the following two tests.

Xanthine In the xanthine oxida (X XOD) system, Soxy (2), which is a species of active oxygen, is generated in 0 (ww) hee, and 5 5 e P oe N de (D PO) and measured by ES. , The quality of gangan (O) was used as the standard, and the sigma ratio of the sump was obtained and compared with the additive. It was confirmed that it had a supra-oxidative activity above 0 in comparison with the signal strength of the added nuclei, and the substance was confirmed to have a chemical action. 2, a species of active oxygen by reaction

(・ O) was generated in 0 (ww) heat, and the quality of saturation was added and measured with 5 5 D me P “roexde (DP). The internal quality of Ngan () The GUN ratio of the sump was calculated based on the GUN of the additive and compared with that of the additive additive.

The substance that has been confirmed to have a sex has a chemical action. In addition to the above, examples of chemical substances with surface-activity reducing effect that can be clearly used are shown below, but the invention is not limited thereto.

A substance in which the chemical compound having a force-reducing action is one or more compound compounds selected from the compounds shown in (() below, or a salt thereof.

(

(()

, R, R, R, and the two hydroxyl groups that are adjacent to the hydroxyl group or its acid group and the inorganic or organic acid group or the acid group are adduct groups. When selected from the above, the upper one of the deviations of RR, R, and R represents the higher grade. It has 8 to 22 carbon atoms, and more preferably N, Sutin, Chin, Styrene, Furo, No, Chi, In, 2 decane, Isosoteane, Chin, 2 Decanoic acid. Item 3 is characterized by the fact that it is the residue of the above.

In the case of (1), A A is good, but A A is preferable, but D A A can be used in industrial applications.

Chemical 2

[] (D)

R 1 and R 2 are methyl or hydrogen, R 1 is a group of an inorganic or organic acid, or is an aldehyde group, and preferably R 4 is a water-soluble ster group. More preferably, the water-soluble starch is A ,,,,,,,,,,,,,,,,,,,,,,,,,,. In the case of F, which is of the case of (n), D-form or D-form can be used in the desired applications. Float, which is a case of (n), can be used for each type type v type type.

Chemical 3]

] (1D)

[Change

, R is selected from the group consisting of chi, in, astaxanthin, xanthine and cupuxanthin, R 2 is the inorganic or organic acid ester or the adduct group, and R 2 is preferably water. It is a soluble steric group, more preferably the water-soluble steric group is It is a soluble organic acid ester of lactic acid, lactic acid, bivin, and a. R thiocyanic acid and amides can be used in the form of s-, s-, s-, and s-types.

[In addition to the above, examples of chemical compounds having surface-activity-reducing action that can be clearly used are shown below, but the invention is not limited thereto.

[A mixture of one or more compounds having a chemical-reducing action is selected from the compounds below. LA A methyl, AA, AsA, AsA, AA pliers AsA 2 tet AA 2 t, AsA 2 steer, AA 2 isostear, AsA 6 t, LA A 6 tet, AsA 6 steer, AsA 6 isostere, AsA 2, 6 tes, AA 26 tes, AsA 26 steers, AsA 2,6 gisteers, AA 2 do 6 tes, AA 2 gu 6 tes, AsA 2 do 6 steers, AA 2 do 6 steers, AsA 2 do 6 ft , LAsA 2 6 te, AA 2 '' 6 te, AA 2 6 steer AsA 2 6 Isosteat, AsA 2 6 ft, AsA 2 in 6 te, AsA 2 in 6 te, AA 2 in 6 steer, LAA 2 in 6 steer, AA 2 in 6 foot, AA 2 in 6 tea, AA 2 in 6 steer, AsA 2 in 6 steer, AsA 2 in 6 steer, LAsA 2 in 6 foot 20 AsA Iso 20 aA in steer 20 AsA N Isosteer 20 AA, Tofu 20 LAA, Ile 20 AsA Nfun, Nong, Pu, Fu, Fumingu Shin, N

It is characterized in that it is a compound of one or more compounds selected from gui and zimethigcine compound, or a salt thereof. The AA that can be used for this purpose is preferably the D-form, and the flo, le, and Y-form can be used for chino, in-acid, and ide. It is possible to use the offset type.

[In addition to the above, use of salts of chemicals with surface-activity-reducing action, such as Sim, Nam, Mu, Am iron, Hydrochloride, Genus, Inorganic acids, etc. This it can.

Ming-no-Ku is a multi-valent gose, a tanop, an isoprono, a drug, a xenanthine, an a, a monseroin, an oleia, a monooingo, an oin. Gusero Oin Gusero, Chin, 2 Zincabon, Sinapine (35 x 4), 2, 5 xyl benzoic acid 5 x, Shear 4 ky, 3 in, Diata, 2 (4 x 4) ) Disperse benzoic acid, earthworm, 5 (phomethy) and the like can be mentioned. This includes, for example, prop, zip, pop, gus, zip, pos, ping, zip, pos, 1, 3 nzio, Examples include chi, square, callus, su, kiss, and loss. These can be used alone or in combination of two or more.

Of these, there are three or more of these, such as gushes, jigs, posins, chitopentas, guss, saccharos, schilos, and ross, and especially preferred. Gus,

The water used in Ming is not limited to ions of p to 3, ions, natural aka ions, acidic electrolytic ions, inus ions, strong, strong aka.

[Although Mingou can be prepared, any of them can also be used and has a particular structure.

Is suitable. Possessive structures include, for example, Zafactin namuo and its compounds, or their aons, cations, nonionics, and sexes, but in the following, the following can be used. Examples of bodies that can be clearly used include fats such as gum, stinkaum and the like; "Achste such as namu, taan, lammom; snum, lares", Tanoa and the like. Oxytin acetylate; ittanum, itatancum, caseinum; akiruatin; adenten; sphatexerol, phosphaticis, phosphatidin; cabonsin, Ions of phosphorus-based ions such as phosphorus; phosphine addition of isostea (phooxytin stearate) octidodeceth (pooxytin tidedecite) Propoxy monostains; penta-synths; poly-synths such as polysynoxys, polysynths Palm fat monotanoad (Ca EA), yam fat tanoad (Ca DEA), roun monotanoad (Rau EA), tannoad (DEA), ra Fat monoacetic acid such as unmonosopronoad (Raw PA), chinmotanoad (Ta EA), chintanoado (Ta DEA), coconut fat methylanoad (Kameti EA) Additions; La Oxine Monote, Nemon Stearate, Sapo Hexapooxytin alkoxides such as pids, stearanoxy, acetylene oxys such as oxides; chinpoixes and other phoscines, hexane oxaquinine polymer glycine , An ion of a thin ion such as cin, an ion of a steapropionmethiane, a fatty acid such as a steatian, and an anisotropy of that and a thin ion of a postin.

, Phosphatidin, phosphatitanoan phosphaticin, sphinne, and other sphintins, zotin, hydrogen, partial hydrogen, hydrogen, partial hydrogen, cytine hydroxide, etc .; System

; A, Ag, Na, Demp conductor, Lagan gum, Aquaqua polymer; Cin-based

Examples include, but are not limited to, more than 12 interfaces of molecular agents.

[Chemical compounds are more preferable as those having an effect such as oxyhydroxide, doublet, hydrogen peroxide, NO diacid, and oxide. Fluoro conductors such as rho (ta E) and fluorine; BBA; gallic acid conductors such as propionic acid propi- ate; vitamin C (AA) and / or its conductors; Phosphoric acid and its conductors; sulfites such as sodium sulfate; hydrogen sulfites such as hydrogen sulfate; thiosalts such as thiona; hydrogen sulfate; hydrogen, hypo, oxello, thio, ogu, and cysteinate. Can be done. As the original drug, anti-vitamins such as og, cysteine, cysteine, ides, glutathione, cysteine, cenbitan A, nzyme Q 0, humpo, po, catechins LAA tedecane, fluoro, etc. And its conductors.

As the chemical substance of Ming Dynasty, the chemical substance having the above-mentioned action of reducing power of Ming Dynasty.

For example, hydrocarbons are higher-grade esters, higher-grade esters, gussets, phosphorus, higher-grade species, higher-grade plants and animals, sterosters, sterosters, sterosters, pods, and funnels. , But not limited to them, and safety is ensured when organisms come into contact with it. .

It is preferable that the temperature at 40 ° C is lower than that at 60 ° C. Examples of qualities that can be used in light are: N, Sutin, Chi, Stearn, Isosteain, Indecin, 2 Kistane, Oin Oin, Noin, Dosaxane, Ipenta, I Soxadecane, Anteisant, Dye, Hydrogen Eyes and their A, Cu, Gne, Calcium soaps, Adducts and other conductors; Raffins (, Raoi), Fluid fins, Fluid raffins, Carbonization of fin-o, poten, poten, poten, squann, obscuran squan stain, etc .; cadwa wax cana wax, issucus, miro montan wax, ozo Waxes such as rye, cecin, finwax, equine wax, petrotum, fisherlo wax, tin wax, tin propinpo Palms; palm, mumm safrawa, lob, hishi, cad, gor, tea, evening primrose, wheat cadian nuts, nuts, innuts, lips, med-fom chic, tikka, moroshi, Rapeseed, wax, wheat, a, cotton, soybean oil, peanut, cocoa, shea, hydrogen palm, hydrogen palm, hydrogen Fats, milk, horses, nunks, and ta's physical properties Oils and fats; B, N, oranges Physical properties;

N, N, adsorbed N, N, N, N, N, N, N, N, N, N, N, N, N, N, N, N, N, N, N, N, N, N, N, N, N, N, N, N, N Gusero, phosphati- s, sphines and other sphintins, phosphatidin, zotins and other; minerals partial hydrogen, hydrogen

Hydrogen, Partial hydrogen conductors; Stero, Stero, Ste, Sterophystello, Steros; Sinos; Stes, Nanstes, Steens, Isosteels, Oinsteins ((

Cidadesi), Cadean nuts Fat fiste, Isostean fiste, Steri firm

Ste, Ste, Isosteatan Octidede, Chin, Octidedede, Octane Octanedece, Stelane Ctyroplo, Octane Penching Capping, Octane 2

2 3 Pungeo, O-Promping, Teraoctane pentahydrogen rosin,

Xanthypron, (Isostearanthin) Tyropunt Thixanthane Pentas (Xysteastane) Penta, Steering, Tereso Steamping Steering, 0, (Castean Noin) Pogse 8, Daiji (Fistia Steer Istea), Daiji Taiiji, Steinijia, Daijijin Compound, Daijihi, Hydrangea Essio conductors; palm fat monotanad (ca EA) palm fat taad (ca DEA), monotaad (la MEA), nocrospo, syn fat, shea And anion such as aluminium, anopropycin, and a cationic scintillation TESIN, POG SENSIN, CABON SIN, SIN, AC

, Cinnamine, a, cin, pepsin, fluorine, cationic and cationic and phosphine, achi and siloxane siloxane, oxyacyl Polymer polymers; two or more selected from phodecane pho-octane, phopotote, etc.

As a clear substance, preferred is A A

Chin, A A 2 6 t, A A 26 t, A A teradecane, As A 6 t, As A 26 t, A A 6 steer, chi, in, chi

Tetoff, Itte, Inn

Te, instear chino steer, astaxanthin, teinpi, carote, carotene, fu, tofu, fu, gushinfuro, metigsif, quin, nzyme, nera ,. Fluid fin, squalane thisopropistin sopro, stin, stissot, stint octadici, stin octidodedecy, isostear stest, 2 stixtant, 2 stint There are some natural oysters such as wow, woodpecker, gupdo, cutlet, amod, rice, onion, pico, zym A, ice, a, Ass, asgas ,, atchia, and, ate, aka, a

There is an animal house in Apricot. Use these alone or in combination with two or more. [As an obvious substance, it is possible to use a raw material or an element.

u t a u, reled grey)

㊦ Zehndle, Zen Press

h r 2

h “n nna h nd bracelet

Gumen 2, C No 4, Engine B (C Gumen However, au g ③ (

7 Gun) ③ Yellow

9 r

t e o 7 un he a o p n at Ruijiniro G (C · Gunui) Gumenska (1 · Gumendo 60) Aurc Brown (C Gumenbun 6) etc. are included. Other typical pigments useful for light inks are Russian (C 74260) Roan (C 74260) Hanza G (C 670) GR (C 200) Nen 4R (C 2), It is a Bunker 6B (C · 10) nut (C1 · 6500). When the properties of these materials and dyes are low, it is also possible to use a composition in which the above-mentioned active substance is dispersed in an amount of 0 to 95.

It is also possible to use a metal or metal oxide as a light-active substance, in which the following substances or metal oxide particles containing a metal oxide are dispersed in the above-mentioned substance in an amount of 0 to 95. it can. The metals and metal oxides that can be used at this time are suitable for manufacturing ink jet inks, for example. Narrow diameter compounds such as deer and anatase can be selected. Furthermore, finely ground metal particles, such as ferrous iron and am-gold, can also be selected for the appropriate application.

Particularly preferred pigments for use as a light-active substance are Gummud 122, C Guny 4 C Gummube 1. , Especially when used for color. The amount of material contained in is usually 0 0 for. More preferably, the amount of pigment is in the range 0-2.

It is also possible to use a substance or a polymer decomposing substance as the transparent substance, and a polymer carbon is preferable. If the salt is sodium or thallium boric acid, or an ammonium salt.

[Clearly usable polymer salts] The following salt salts can be used. Poaku, Aku Akupo, Akuka Mu Akupo, Biaku Stepo Aku Aku Aki Stepo-like Acrylic, Stain Akupo, Stain Mekaku Po, Stainaku Aku Aki Stepo METHY STR ACT ACT a METHY STYRENE ACT ACT ACT ACT ACT NO ACT ACT; Insulation Imp, Tan Akpo, Chimp,

Chimpo, In Step

Luke Npo Akpo

It is also possible to use salt or porosity salt.

The molecular decomposition is performed, for example, high molecular weight ax, high molecular weight aus, high molecular weight abundance, bone, sodium salt, salt of a salt and axon on, 4 ammonium, black

Mu salt and mu thione, and oxy thiocin auxin and nitro oxy thiocin auxin on. The amount of molecular decomposition is 0 0 5 0, preferably 0 to 3 with respect to.

[The preferable content of or in liquid is 0 to 99 99 relative to the composition amount, and 0 0 9 9 is preferable.

The soluble substance of [is not particularly limited, and is preferably a substance having the above-mentioned chemical action.

The preferred content of the water-soluble substance and the water-soluble substance in Ming is 50 to 95, which is about 9 to 9 9 relative to the composition.

[There is no particular limitation on the amount of the compound that has the effect of reducing the force of light, and it is preferably 0 000 to 45 and more preferably 0 to 20 with respect to the composition amount. It is not preferable because 0/0, which also has a force-reducing action, can produce a child that exhibits a sufficient anti-reaction action, and that it can have a viscosity of more than 45 to be used.

[Although there must be a large amount of lucid force-reducing action added to the equilibrium, it is preferable to increase the qualitativeness of emulsification from 0 000 to the composition amount. 40, and more preferably 00 to 40. Also, it is not preferable because it does not weaken the oxidative effect when it is used over 45.

The 23 substances of light are preferably 10 to 0 G or striated, or preferred.

When adding other clear ingredients, make sure that the Before adding, add it after dissolving or dispersing it in the sexual substance, add it after adding the total amount of the sexual substance, or add it during the process of adding the sexual substance. . Add water or water first, use the first part, and add the rest later.

For the sake of clarity, the qualitativeness of the claim 2 is kept good under 00 m, preferably with an average in the range of 0 m to 30 n.

[This is especially true for weaves such as the skin of Ming. The reason why Akira is to the living body is that it is considered that the biocompatibility is deteriorated because the Akatsuki's chemical component uses a vitamin and its compound derived from a living body component.

Ming is pharmaceuticals, pharmaceuticals, cosmetics, cosmetics, external ionic compositions, vibrational compositions, electromagnetic compositions, thermal compositions, electrolytic compositions, foods, foods, functional foods, foods, feeds, aging, oxidation, and antioxidants. It only needs to be one or more compounds selected from.

In the future, pharmaceuticals, pharmaceuticals, cosmetics, cosmetics, external use, ionic composition, vibrational composition, electromagnetic composition, thermal composition, electrolytic composition, food, food functional food, food, feed, aging, antioxidant are selected. In the range of 0.005 to 90, the amount of quality substances and active substances in the case of one or more compounds is added to the amount of the final agent.

This is because it is difficult to manufacture a child with a temperature of 90 or more, and the effect is reduced with a temperature of 0.005 or less.

[Indicates that at least one of pharmaceuticals, pharmaceuticals, cosmetics, cosmetics, external use, ionic composition, vibrational composition, electromagnetic composition, thermal composition, electrolytic composition, food, food, functional food, feed aging, antioxidants Of the biological material of the combination of

It is sufficient to administer and administer the drug containing it in a physiologically acceptable range, and specifically, it should be 00 ppb to 09 d ay when calculated for a body weight of kg or an organism.

For the formulation of Ming, if is from to 3.

[Alternatively, we can see that pharmaceuticals, pharmaceuticals, cosmetics, cosmetics, external ionic composition, vibration composition, electromagnetic composition Composition, electrolytic composition, food, food, functional food, feed, aging, oxidation, antioxidants, and one or more compounds selected for their physical effects are whitening and pigmentation. Remedies for skin, good for rough skin, good for oil, good for dryness, small for pores, remedies for blush, hair loss, promotion, burns, skin remedies, skin remedies Can have a curative effect.

[Also, the emulsification of the present invention required to obtain these results varies depending on the type, but only if it is 0 pp 00.

This 100 can also be prescribed as the final drug of that of claim 2. It is recommended that the dosage of the preparation be 0. 0 to 50 in quantity. If it is applied to the skin of body 2 at this time, the skin is c 0 .0 m 0, and if it is administered by oral administration or the like, the body weight is 60 k or 0 .0 m to 1. At least one selected from pharmaceuticals, pharmaceuticals, cosmetics, cosmetics, external ionic composition, vibrational composition, electromagnetic composition, thermal composition, electrolytic composition, foods, foods, functional foods, foods, feeds, aging oxidation, and antioxidants. The following can be theoretically accepted.

It can also be prepared by compounding with an agent of the following state in accordance with the conventional method of Ming. ,, Emulsion, Cum, Powder, Dispersion, Multi-layer, S, Ge, Solid, Powder, Pet, Emulsion can be selected.

According to a conventional method of the present invention, it can be prepared by compounding with an agent in a state known as an external composition. For example, milky lotion, makeup, beauty care, cosmetics, oil, care products, makeup, agents, hair nourishing agents, foundation cosmetics for makeup, makeup, facial cleansing and whole body, foundation white powder cosmetics. It can be used as cosmetics, dispersion chemicals, etc., and can be selected from multi-layered emulsion, soot, gel, solid form, powder.

[

In addition to the above components, the ingredients used in various agents, namely (hot spring water, deep layer), oil agents, metal salts, agents, powders, water-soluble molecules, etc. Film, Fat, inclusion, protection, antibacterial, fragrance, deodorant salts, P, refreshing, animals / biological products, plant products, vitamins, nucleic acids, hormones, cells, blood stimulants, harvesting , Anti-reactive oxygen keratolytic,

It is possible to add more than one kind and to add them in the range of 0.00 to 90, preferably in the range of 0.0 to 50.

Examples of the above-mentioned substances that can be added to the cosmetics, whether they are used in ordinary cosmetics, are natural or synthetic, and whether they are solid, semi-solid or solid, It is possible to use hydrocarbons, corpuscles, types, higher grades of stainless steel, foot, and slip. As an example of the oil agent that can be used obviously, the oil agent described in Japanese Patent No. 2044-5 can be used.

In addition to Aeon cations, there are aeon cations, non-ionics and cations, but in Akira, ionics can be used. Can be added to

For example, the one described in Japanese Patent No. 2004 4 6 9 5 2 3 can be used.

[As a metal set that can be added to Japan,

As the agent which can be added by adding the set listed in 2004 2 6 9 5 2 3 the quality listed in the Japanese patent, 2004 2 6 9 5 2 3 is used. I can also do it.

As the dyes and pigments that can be added in addition to Akira, it is also possible to use the qualities listed in Japanese Patent No. 2004 26 9 5 23.

As the materials that can be added in addition to those described in Japanese patent publication, the quality listed in Japanese Patent No. 200 4 26 9 5 2 3 can be used.

[As a water-soluble molecule that can be added in addition, the quality described in Japanese Patent No. 2004 4 6 9 5 2 3 can also be used.

[You can use the quality listed in the Japanese Patent, 2004 2 6 9 5 2 3 if you can add it.

[For the P that can be added in addition to the above, the quality described in Japanese Patent No. 2004 4 6 9 5 2 3 is used.

[As the animal and biological products that can be added in addition to those described above, the substances listed in Japanese Patent No. 2004 4 6 9 5 2 3 can be used. 6

[For natural products that can be added in addition to those described in the above, it is also possible to use the qualities listed in Japanese Patent No. 2004 4 9 5 2 3].

Bits of Japanese patent, 2004 26 9 5 2 3

It is also possible to use the materials of Kaya.

[For the types, nucleic acids, and elements that can be added by adding to Japanese patents, refer to Japanese Patent, 2004 2 6 9 5 2 3

You can also use the quality listed.

[As a blood-enhancing agent that can be added to and added to the protein of the present invention, the quality described in Japanese Patent No. 2004 269 5 23 can also be used.

[When used in cosmetics, the following components can be added.

This component includes, for example, hydrocarbons, stes, glycerides, higher grades, polyvalent grades, lower grades, nonionic anions, and amphoterics.

Examples include ultraviolet rays, oxidation, oxidization agents, solubilizing agents, antiseptic agents, preservatives, sterilizing agents, pigments, fragrances, powders, and water.

In order to contain lantern, it is possible to add the existing raw materials listed in the compendial in a pp 90 amount to that which is generally or preferably contained. The raw materials listed in the compendials listed above are, for example,

Japanese Pharmacopoeia, Japan Official Book Association, Published by Ho, Inc., Published in 2004, Cosmetics Solution, Japanese Official Book Church 984 (Kojitsusha) Cosmetics, Ministry of Health and Welfare 199 3 (Kojidaisha) Cosmetics

Ministry of Health and Welfare, 99 3 Jibunsha), Classification by makeup type, Ministry of Health and Welfare, 993 (Jiitsusha) ternat ona Cosmet c ngred ent Dc onary and Handbook 2 002 Nn h Ed t on Vo ~ 4 by CTFA Cosmetics

You can use all charges listed in 3 (ke).

By using a combination method of at least one selected from the following: ion, vibration, electromagnetic, and heat / electrolysis.

It is possible to increase the outcome of 6 points.

・ 006 5] If Ming of claim 6 7 is dispersed in water, Ming of

It can be manufactured by shaping a child. , It is easy to manufacture the product of the present invention by applying a water flow exceeding a certain force to it. ・ 7

It is possible to set the distribution range. However, it is preferable to use a device for adding a cleavage shape when the emulsifier is placed under 200 m. More preferably, it is possible to produce 000 m-sized particles dispersed in water and water-based agents in the form of a small amount of 15 s. As for the flow of the constant power, the power of the specially required tap water is sufficient. Or, it is possible to mix the water stored in the tank as usual.

[

Examples of the device for adding a shape include ,, a mixer, a mixer, a mixer, etc., but it is preferable to use a static mixer, a jig dis- gector, and a cupro-phytochemical quantifier a. It is also possible to use at least one kind of arrangement from the group consisting of O.

[Alternatively, a jetterget etd sperga or) that dissipates the onion in a small volume in the nose can be used. Other suitable arrangements include the Croporus fitter, the Ikuposugarasufita, and the cro d zer ao G a Naiza Noz. A zip detector is the preferred device. Thus, the important feature of Ming is that in this Ming method, the size of emulsification (the d expression in the specification) is reduced, and that of the child size cloth (the d dIII expression in the specification, (d indicates the size). According to Ming's law, we shape by the degree disclosed explicitly, and ddd is at least 20 and preferably 3 less than the value obtained by the above-mentioned method without force. This is done after the phase inversion is completed. Jeddy targets have a size where the available money is dissipated in a small volume that is available in the dispersion range, which is used to obtain highs. As a good tattoo mixer, there is a mixer that can be used by S zer W eh and Swiss Noduit (SX). The general point of all static kissers is that the body at is constantly separated and rearranged, combined and redistributed by internal elements. The static mixer is thereby operated in a manner similar to that of a jitter detector, ie the available energy is available in the static mixer. A pressure drop between the high, 0 0 to 500, preferably 0 5 50, transferred through the polymer unit containing the child appears. 0 5 to 50 are relatively simple and expensive It can be generated by a pump. The (control) is high, with at least 100 S preferred from 00 to 2000000 s, and most preferred from 35,000 to 500000. It depends on this pressure drop. [Below, the implementation will be described in more detail, but is not limited to these implementations. It should be noted that the following gussets were used with a content of over 9 8. Also, as the Surfactin Na (AF), we used AF (Shikisha) manufactured by Showa Shikisha. The weight shown is. APPS (Na AsA 2-6T), VE (NaNro; O), VCP (AsA Tera; Ke), TDG (Fuming Thin :)

1:

Xen 20 APP, until you get one

The composition was created.

[2] Squealer C P was added until it became one. This work was repeated 4 times. Then, Squan 4 was added until it became equal. This work was repeated 2 times to get the real thing.

[3:

As mentioned above, APP VEP TDMG and safactinum were added to the lysate and dissolved, while a small amount of the oyster compound below was added. Then, water and 3 butanedio were slowly added to finally obtain the eu compound 60 gusen 23, 3 ngeio 3, 3 APP 0 VEP0 TDMGO 5, and safactinum mei.

(Oy compounds) The following substances were added to each other, and squalane was added at the end to give 100.

A A Chin, A 2 n 6 te, As A 2 n 6 te, A A te, A A 26 te, A A 6 steare, Chino, In Chino te

Inteinte, Insteer, Tisteer, Astaxanthintein, Pinrotintin, Fro-P-Floin-Methin-Sin-Flo, Met-In-Sin-Flo, Kinin, Nzyme A, Non, Nine, Liquid Fi Squan, Chin Sopropy, Sutin Sopropy, Sutin, Ste Iso, Sutin Octasi, Sutin Octide Desi, Nera Liquid Fin Isostea Steste 2 Til Xan Guse, 2 Xan, Hiwa, Op, Azalea, Gupshid, Kanut, Ammond Rice , Octamethylene siloxane, methite siloxane, typosiloxane, octametyl cycloteroxane, pic, Nzyme A, methicyl pentapentane xanthate siloxane siloxane, methicyl cyclosiloxane, methypochloroxane, meth Fupsiloxa

[4: (Cosmetics, pharmaceuticals, pharmaceuticals)] A was prepared by dissolving APP in the gauze while adding a small amount of a sex substance. Solution A was added to port 80, solution B dissolved in port 80 was added, and the mixture was mixed with a mixer at 5000 P for 5 to make it uniform. Then, the Ag solution of Formulation C was added, cooled while stirring, stopped under 4 and left to stand. Was measured at 00n.

A sex mixture 6 ghen 4 APP 2 and sex mixture were mixed in the lower direction. AA chin AsA 2-6 te, AA 2 6 te, AA te, AA 6 te AsA 6 steer chino, i, chinotate, inte, inte, instaate, chisteer, astaxanthin, teinpi, Kachin Carotene, Fu, Furo, Tofu, Methyg cinph, Metigu cinnph, Kin, Nzyme A, No 0 were mixed and squalene was added to 0.

[B: 300000 a 2, Stearn 0 5

C Aging 0 1

[5: distributed

In step A, the safactin name was dissolved in the ginseng, while the following substances were added in small amounts to prepare.

[A: lower sex mixture 16 and gusten 4 AP

VEP TD, Surfactin sodium 0 2. The following changes in the sex mixture. AA Chin, AA 2-6, AA-te, AA 26-6 AA 6 steer Flo, p-Flo Y-Flo, Methyl Glucin-Flokin, Nzyme A, and No-Chinote 0 0 Mix and add squalane to 00.

[B: A 2, Steen 0.5, and [A] were added to 8 mouths, B solution dissolved in 80 mouths was added, and the mixture was adjusted to 5000 Pm 5 with a mixer to make one. Then, an Ag solution of Formula C was added to the mixture, cooled while being cooled, stopped under 4 and left to stand to prepare a rice cake. It was 35 n. Including those who wear and use this for daily use, 17 people use 2 times a day (4 CC per time) on the affected area and apply it externally for 90 minutes.

The number of dyes decreased and the number of dyes decreased 90 minutes after the start of use. In addition, a similar test was performed using ion ultrasonic waves manufactured by Kagoshima Sonic Research Co., Ltd., and there were two or more improvements in dye attachment. When the pups were added to the feed, feed oxidant, and antioxidant at 0 ° C, their oxidization was suppressed and discoloration was suppressed, and the life of the product was prolonged about twice. It was confirmed that the results obtained were able to be exhibited. , Cosmetics of the present invention By the method of making the cosmetics of the same composition.

The cosmetics that were manufactured were re-introduced, and an accelerated test at 40 ° C was conducted, and the color was checked for a while.

It was colored and left alone, but almost nothing was found in the bright cosmetics. Moreover, it was observed in all patients who used the pump that the two samples were used after the accelerated test, but the skin of the clear cosmetic was confirmed to be safe, confirming its safety.

6: distributed

In step A, the safactin name was dissolved in the guss while adding a small amount of the following substances to prepare the ingredients.

[A

The lower sex mixture 6, Gushen 4, Surfactinum 0 2 APP 0

The following is the sex mixture.

A chin, A 2 nd 6 te, A A 2 nd

TE, AA TE AA 26 TE, 6 steer, TE, IN, TE, INTE, INTEIN Steer, Chisteer Astaxanthin, Tain, Pin 6 Carotene Carotene, Flo, F, Y-Flo, Met-Syn-Flo, Met-Synthoff, Kin, Nzyme A, o In addition, it was 0.

[The solution of B 2, Stan 05, and A was added to 80 ports and the solution B dissolved therein was added to 8 D, and the mixture was adjusted to 5000 Pm 5 with a mixer. In addition, the compound water () of this AB is fed into a tactile mixer, a jig distorter, a croposer fighter, and an equalizer, respectively.

1 It was dispersed by Naizanoz and dispersed into one, and it was naturally cooled until warm.

[Each dispersion was measured to have a static mixer of 2 34 m, a jitter detector of 27 m, a cuposcope of 20 m, and an extract of 94 m a o G a 1 Naiza Noz 5 3 m.

7: The safactin name was dissolved in the above-mentioned A-grass while adding a small amount of quanta to prepare. Solution A was added to 70D, and solution B was added to the mouth 70 and dissolved, and the mixture was adjusted to 50000 Pm with a mixer. Further, while cooling with water while preserving the water of the formulation C, the solution was stopped under 40 and left to stand.

A: Qualan 6 Ghen 4 Safactin Natom 0 APPS 0 7 TD G 0 VEP 0

[B: Stearn 0 5 a 2 Preservative

C Agin 0

[8: Dispersion: A was used to dissolve the safactin sodium in the gusset, while adding a small amount of the substance below to prepare.

[A; The following is the sex mixture 5 and the gusen 4 APP 02 sex mixture below. The mixture was mixed with 30 and Fluorine and added with tinic acid to obtain 00.

[B: a 2, stean 0 · oo, [a A was added to the 80 port and the solution B dissolved therein was added, and the mixture was adjusted to 5000 pm 5 with a mixer. Rani Shinaga Add the Aki solution of Formulation C, cool from

I stopped it and left it for a while. The temperature was 34.5 nm. This is used as a coloring agent for medicine, cosmetics, cosmetics, food, food, external use, ionic composition, vibration composition, electromagnetic composition, scavenging composition, electrolytic composition, functional food aging, feed, feed additive, oxidation, and antioxidant. Agent, ink

Ink ink non-ink ink, photographic film When optical particles are added by 0 5, they can be extended to 3 times as long as the original of each product, and the resolution is stable due to the fineness of the elementary particles. It could be a pigment particle containing a chemical substance.

9 APP surfactin sodium was dissolved in the A-dispersion sample, and the following substances were added little by little to prepare.

A Sexual mixture under 2 Xen 4 APP

VEP 0 Surfactin name 0. The following are sex mixtures: Mix 0 n 5 fluoro and add acid to 0 to mix.

Sex mixture.

[00] B A 2, Steen 0 5, and A were added to 8 ports, and the dissolved B solution was added to 80 ports, and a mixer 5000 P, 5 was added. Add the quinine solution of Formula C from Rana-shina, and cool from Shinana.

I stopped it and left it for a while. The temperature was 34 bnm. This is used as a magnetic material for pharmaceuticals, cosmetics, vibration composition, electromagnetic composition, thermal composition, electrolytic composition, materials, ink, ink ink, and sexual memory. It was confirmed that it was possible to create a memory or a memory with a high degree of stability.

[0 2 0 dispersion] was prepared by adding APPS to the A-cell and adding a small amount of the following substances.

[0 03] A lower sex mixture 0, the following ones 4 APP 0, Surfactin a 0. Sen was added to the mixture containing the following quality while adding 0 PP to 0. It was a combination of AA Tell, LA A, AA Pi AA LA A pliers, LAsA 2 te AsA 2 te, AsA 2 steer, AsA 2 steer AA 6 te, AA 6 te, LA A 6 steer, AA 6 Isosteer, AA 2, 6 dite AsA 2, 6 te AA 2, 6 steer AsA 26 steer, AA 2 good 6 te AsA 2 6 te, AsA 2 good 6 steer, AsA 2 good 6 steer, AsA 2 good 6 ft, AsA 2 6 te, AA 2 6 te, AsA 2 6 Steer, AA 2 6 Steer, AsA 2 6 Fu AA 2 Rain 6 Te, AsA 2 I 6 Iso Te, AsA 2 In 6 Steer AsA 2 I 6 Iso Stea AA 2 In 6 Fe, AA 2 In 6 Te , LAA 2 n 6 iste, AsA 2 n 6 steer, AsA 2 n 6 steer, AsA 2 n 6 fin 20 AA, Iso 20 n AsA n steer 20 LAsA n, Isostea 20 LA A n 20 LAsA, A 20 AA, N, N, N, F, T, M, N, N, N, G, I, and an immiscible mixture of the following. Carbon 5 and fluoro were mixed, and then tinic acid was added and mixed 100 times to form a uniform dispersible mixture.

[B: A 2, Steen 0 5, and A of A were added to 8 and the solution B dissolved in 8 mouths was added, and the mixture was mixed with a mixer at 5000 P and 5 to make them one. In addition, the Ag solution of Formulation C was added, and the mixture was cooled while being cooled, and allowed to stand under 4 and left to make a rice cake. The measured value was 295n. Pharmaceuticals for this and other purposes Pharmaceuticals, cosmetics Cosmetics, foods Foods for external use, ionic composition vibrational composition, electromagnetic composition thermal composition, electrolytic composition functional food, aging whitening, pigmentation goodness, second treatment Good for rough skin, good for oil, good for dry, good for small pores, for treatment of blush, for treatment of hair loss, for growth, burns, for skin burns, for skin problems, for 78 people 2 times a day. 5 CC) was applied to the affected area and was applied externally for 60 minutes. Ion, vibration, electromagnetic, thermoelectrolysis The commercially available product was used. When the pups were added as feed, feed, oxidant, and antioxidant at 0 to 5 degrees, their oxidization was suppressed, discoloration, and the occurrence of blemishes were suppressed, and the life of the quality of the product was approximately doubled. It was confirmed that the results obtained were able to be exhibited.

Clearly usable chemical substances having a surface force-reducing action can be evaluated by the following force-reducing action, as long as the surface-reducing action is positive. If the above two tests under the force-reducing action are positive, the usable surface-reducing action is judged to be positive. , Pour water into a tank with a diameter of 20 and drop oil on the surface of the water to float the oil in a circular shape so that the oil has a small diameter. Next is the degree of purification.

This is the case when it was observed that the circular test oil was dispersed in the center of the test material at the boundary of oyster of 20 C and humidity of 50 and spread to the surface of the tank. 2. Measure the force of the solution of the chemical substance using a Kyowa Gakusha dynamometer (CBVP A3).

First, a substance having a surface force difference above the comparison ratio of 0 when used at a boundary of 20C and a humidity of 5 is positive for the force lowering effect of the present invention.

Whether the above 2 tests are positive or not is positive and the chemical action that can be used is positive. , Xanthixanthine oxidase (X X), which is a species of active oxygen, is a species of active oxygen (2 ·).

5 5 e

Measured by ESR, supplemented with P O e d e (PO).

, The quality of gun (O) was used as the standard, and the GUN ratio of the supplement was calculated and compared with the addition. It was confirmed that the substance had a higher level of sulfurity than that of the gut level of the added substance, and the substance that has been confirmed to have the chemical action was regarded as the selenium compound. 2. Generated (.O), which is a species of active oxygen, in 0 (ww) heat by photometry, supplemented with 5 5 eoexde (D PO) with addition of a quantity of saturation, and measured by ESR did. Then, the Gna ratio of the supplement was calculated based on the signa of gangan (O), which is the internal quality, and the additive was compared. It was confirmed that the substance had a property above 0 in comparison with the gnosis degree of the added substance, and the substance that has been identified has a chemical action.

According to the above-mentioned usability, a unit of more than a species of gas or liquid is a compound thereof, and a unit of a plurality of a substance of a dissolved or dispersed compound having a surface force lowering action is a compound thereof. It is possible to provide an emulsifier with good stability and high safety by forming the child with an aqueous solvent from raw materials composed of more than one kind of organic substance.

Claims

Wanted

[

All of the chemical substances with a force-reducing action were formed [2]

All of the chemical substances having a force-reducing action were formed, and the side of which the antioxidant substance or the fatty substance was included.

[3]

All of the chemical substances that have a force-reducing action were formed, and on the other side, the chemical substances or water-soluble substances were included.

[ Four ]

All of the chemical substances that have a force-reducing action are formed, and that is a multilayer structure.

[ Five ]

All of the chemical substances having a force-reducing action are formed, and they have a multi-layered structure, in which an antioxidant substance or a water-soluble substance or an oil substance is included.

[6]

At least one species of chemical compound having a force-reducing action is composed of the compound, and at least one species of glucene or liquid is composed of two elements of the compound.

[7]

At least one species of chemical compound having a force-reducing action is a compound, and at least one species of gas or liquid is a compound, chemical compound and / or a substance of oily substance or water-soluble substance. The above unit consists of three elements of the compound

[8]

And 7 or more of them were dispersed in the mixture of water or more than one kind of liquid solvent.

[9]

To 7 contained water or more than one kind of liquid solvent dispersed in the mixture.

[0]

Min or contains antioxidants

[

Because it is in the range of 0 to am 0 [Starting from 2 are pharmaceuticals, pharmaceuticals, cosmetics, cosmetics, external use, io composition, vibration composition, electromagnetic composition, thermal composition, electrolytic composition food, food functional food, food, feed, aging, oxidation, antioxidant , Ion, ink jet, ink jet, photographic film optical particles [3] selected from ion input, vibration input, electromagnetic input, heat input, electrolytic input Another method to increase the effect of method 2 by introducing and infiltrating into the tissue.

Use [1 4] to add a small 5 S to shape

5 per 1 000 m dispersed in the agent is manufactured.

The [5] form is a small species selected from the group consisting of a static mixer, a jig displacer crospter filter hood, a scooter, and an acropherizer atoat Naiza noz. Is used to manufacture a billing quadruplet.

6]

Standardization of chemical substances by 1 to 5

[7]

7 if the chemical compound having a force-reducing action is a compound selected from the compounds represented by the following (, (, and (), or a compound of two or more compounds, or a salt thereof.

[Change

))

, R, R, R are hydroxyl groups or their acid groups are inorganic or organic acid groups or, or the two hydroxyl groups that are adjacent to the acid group are aldehyde groups. Selected from Sometimes R, R, R, and R are higher by one than the other. More preferably, it has 8 to 22 carbon atoms, and more preferred is Sutin Chin Stefan Fluor.

-, Thi, in, 2 decane isostearin, tin, and the residue of 2 decanoic acid.

(2)

[] ()

, R to R methyl or hydrogen, R is a group of an inorganic or organic acid or a group of aldehyde, and R4 is preferably a water-soluble group. 3 is characterized in that the water-soluble starch is a soluble organic acid salt of asbin ,,,, lactic acid, vin, and ano.

Chemical 3]

] ()

The coalescing of poids is as follows:

[]

O

R 2, thi, in, astaxanthin, xanthine, xanthine, R 2 is an organic acid salt or Is a aldehyde group, preferably R2 is a water-soluble steric group, and more preferably a water-soluble steric group is a solvent for asbin-n-lactate, vin, and ano. (1) to (3), which is characterized by being acid ester.

[8

The mixture having one or more kinds of chemical compounds having a force-reducing action selected from the following compounds is described in 7 if they are the same.

Asbin Mechi, Asbinchi, Asbin Propias Asvi, Asbin Pliers, Asbin 2 Te, Asbin 2 Putty, Asbin 2 Steer, Asvi 2 Steer, Asbin 6 Te, Asbin 6 Te, Asvin 6 Steer Asvin 6 Steer,

Asvi 2,6 Tee, Asbin 26 Te, Asvi 26 Steer, Asbin 6,6 Steer, Asvi 2 Do 6 Te, Asvi 2 Do 6 Te, As Bin 2 Do 6 Steer, As Bin 2 Do 6 Steer , Asvid 6f, Asbi 26t, L Asbin 26t, Asbin 26stear, Asbin 26stear, Asbin 26, Asbin 2in 6t, Asbin 2in 6 Tes, Asvi 2 in 6 Steat, Asbin 2 in 6 Steat L Asbin 2 in 6 Fu, Asvin Yun

Tet, Asbin 2 in 6 Te, L Asbin 2 in 6 Steer Asbin 2 in 6 Steer, Asbin 2 in 6 Hu, Y 20 Asbin, Iso 20 L Asbin, Steer 2 0 Asbin 2 Isosteer 20 Asbin, Hu 0 Asbin, Lee 20 Asbin, Hung, Puffer, Fu, N, Gu, Lee

It is characterized in that it is a compound of one or more compounds selected from organic compounds or a salt thereof.