WO2006061877A1 - Extrait de propolis a dispersibilite dans l'eau amelioree, boisson contenant du propolis, et procede visant a ameliorer la dispersibilite dans l'eau d'un extrait de propolis - Google Patents

Extrait de propolis a dispersibilite dans l'eau amelioree, boisson contenant du propolis, et procede visant a ameliorer la dispersibilite dans l'eau d'un extrait de propolis Download PDF

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Publication number
WO2006061877A1
WO2006061877A1 PCT/JP2004/018163 JP2004018163W WO2006061877A1 WO 2006061877 A1 WO2006061877 A1 WO 2006061877A1 JP 2004018163 W JP2004018163 W JP 2004018163W WO 2006061877 A1 WO2006061877 A1 WO 2006061877A1
Authority
WO
WIPO (PCT)
Prior art keywords
propolis
water dispersibility
propolis extract
extract
improved
Prior art date
Application number
PCT/JP2004/018163
Other languages
English (en)
Japanese (ja)
Inventor
Rindai Yamamoto
Original Assignee
Rindai Yamamoto
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rindai Yamamoto filed Critical Rindai Yamamoto
Priority to PCT/JP2004/018163 priority Critical patent/WO2006061877A1/fr
Priority to CN2004800445476A priority patent/CN101083915B/zh
Priority to TW093140567A priority patent/TW200621169A/zh
Publication of WO2006061877A1 publication Critical patent/WO2006061877A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52—Adding ingredients
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L21/00—Marmalades, jams, jellies or the like; Products from apiculture; Preparation or treatment thereof
    • A23L21/20—Products from apiculture, e.g. royal jelly or pollen; Substitutes therefor
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A61K35/64—Insects, e.g. bees, wasps or fleas
    • A61K35/644—Beeswax; Propolis; Royal jelly; Honey

Definitions

  • the present invention relates to a propolis extract with improved dispersibility in water and a beverage containing such a propolis extract.
  • Such a propolis extract is supplied in a dropper bottle or the like in which a dropper is set in a cap as a liquid (propolis liquid) that can be mixed with ethanol or other suitable solvent and dropped with a dropper.
  • a liquid propolis liquid
  • 20-30 drops of the liquid is dropped into a suitable amount of water, hot water, milk, coffee, tea, juice, honey, drinks or alcoholic beverages, in the morning, noon and evening. Ingested orally three times a day, or in the morning, noon, candy, and 4 times a day before going to bed four times a day before going to bed, it is said to be taken orally by dropping into the beverage.
  • the water-insoluble component of the propolis extract is dissolved in the beverage. It may become “swift” and float on the surface of the beverage, or may sink and adhere to the bottom or side of the container, making it impossible to take the required amount.
  • ingredients that float on the surface of the beverage may stick to the drinker's teeth, gums, tongue, palate, or throat during drinking and may not be able to be effectively consumed, and even after drinking For some time, discomfort or irritation continues.
  • the propolis extract is so-called “bitter taste” in terms of taste, and feels “spicy” at the time of quoting, and it is generally difficult to drink because it smells too strong.
  • means such as capsules.
  • the amount of a single dose is 20-30 drops! / 50-50 and so many drops! It was suitable for drinking! /, Became large, or increased in the number of capsules to be consumed at one time.
  • Patent Document 1 proposes a technique of adding and blending milk proteins such as milk casein.
  • Patent Document 1 JP 2001-169736 A
  • the present invention improves the above-mentioned conventional problems, that is, the disadvantages of propolis having excellent characteristics without using milk protein or the like, adhesion to containers, oral cavity and throat, flavor
  • the object is to provide a method for improving the difficulty of improvement and a propolis in which these drawbacks are improved.
  • the water dispersibility-improved propolis extract of the present invention is a propolis extract by alcohol extraction as described in claim 1, and is sodium carbonate, Z, or hydrogen carbonate. Water-dispersible modified propolis extract heat-treated in the presence of sodium.
  • the propolis-containing beverage of the present invention is a propolis-containing beverage containing the water dispersibility-improved propolis extract as described above.
  • the method for improving water dispersibility of a propolis extract of the present invention is a propolis extract obtained by alcohol extraction, wherein the propolis extract has a constitution in which heat treatment is performed in the presence of sodium carbonate or Z and sodium bicarbonate. This is a method for improving the water dispersibility of products.
  • the invention's effect is a propolis extract obtained by alcohol extraction, wherein the propolis extract has a constitution in which heat treatment is performed in the presence of sodium carbonate or Z and sodium bicarbonate.
  • the water dispersibility-improved propolis extract of the present invention since there is no attachment to the container, the oral cavity or the throat, there is no wasteful part attached to the container, so that the entire amount can be ingested.
  • the container can be easily cleaned after use, and it can be used repeatedly, and it is not necessary to carry a dedicated container when going out, and the discomfort caused by attachment to the oral throat, An unpleasant taste with no unpleasantness and a long-lasting odor is prevented.
  • a beverage containing a propolis extract that is easy to clean, and can contain only a small amount of beverage that can be drunk in a single or half mouth, but can contain the necessary amount of propolis for a healthy person It can be.
  • FIG. 1 is a chromatogram obtained by high-performance liquid chromatography of a propolis solution before treatment for improving water dispersibility.
  • FIG. 2 High-performance liquid chromatogram of propolis extract (A) with improved water dispersibility.
  • a propolis extract obtained by alcohol extraction is obtained in the form of a propolis solution dissolved in ethanol.
  • the content of the propolis extract in this propolis liquid is generally 20-33% by volume, and in addition, some water (about 10-15% by volume) and ethanol (remaining amount).
  • the propolis extract contained in such a propolis liquid is subjected to a heat treatment in the presence of sodium carbonate or Z and sodium bicarbonate.
  • the amount of sodium hydrogen carbonate and the sodium carbonate water dispersibility improver varies depending on the content of the propolis extract contained in the pour-polis solution to be used. In the case of 33% by volume of propolis liquid, it is 0.5% by mass or more and 2% by mass or less. At this time, if the addition amount is less than 0.5% by mass, sufficient water dispersibility improvement effect may not be obtained. Moreover, if the added amount is close to 2% by mass, a sufficient effect of improving water dispersibility can be obtained, and even if added in excess of 2% by mass, it does not dissolve in the propolis solution, and it appears to be unreacted even after heat treatment. In some cases, it may be necessary to remove the powder by means such as filtration. In the case of a propolis liquid having a different volume content of the propolis extract, the water dispersibility improver should be converted so that it falls within the range of the ratio of the propolis extract and the water dispersibility improver in the above example. Added.
  • a preferable heat treatment temperature has a lower limit of 40 ° C. or higher, desirably 50 ° C. or higher, and an upper limit of 70 ° C. or lower, desirably 65 ° C. or lower.
  • propolis extract obtained by alcohol extraction
  • water dispersibility-improved propolis extract heat-treated in the presence of sodium carbonate, Z, or sodium bicarbonate uniformly emulsified?
  • this water dispersibility-improved propolis extract has a high ethanol content, so if it is sealed, there is no risk of spoilage.
  • each major component of quercetin, kaempferol, diterpene, and paracoumaric acid which is considered to be an active ingredient in the propolis extract, does not change before and after the treatment. There is no difference in the components or the results of high-performance liquid chromatography. In addition, no change was seen before and after the water dispersibility improvement treatment in the analysis using an absorptiometer in the ultraviolet region.
  • the water dispersibility-improved propolis extract thus obtained is excellent in water dispersibility, so that the components settle even when mixed with general soft drinks, tea, tea, etc. at various mixing ratios. There is nothing to do.
  • a propolis-containing beverage can be easily obtained by blending the water-dispersibility-improved propolis extract in the production process of these soft drinks, etc., so that masking of the odor peculiar to propolis becomes easier. Easy to drink or drink.
  • the propolis solution is an ethanol solution containing 32% by volume propolis extract (however,
  • sodium bicarbonate (NaHCO3) in the amounts shown in Tables 1 and 2 was used.
  • the pH of the water dispersibility-improved propolis extract in Tables 1 and 2 is about 6.7-6.9 compared to 5.3 for the original propolis solution. It was almost neutral.
  • Fig. 1 shows the chromatogram of the propolis solution before the water dispersibility improvement treatment
  • Fig. 2 shows the chromatogram of the water dispersibility improved provolis extract (A).
  • the water dispersibility-improved propolis extract (A) was evaluated for the degree of adhesion to the container at the same time as the evaluation with the propolis liquid without the water dispersibility improvement treatment.
  • Kenferrol and quercetin were measured under the above conditions, except that the detection wavelength was 380 nm. As a result, these components having peaks at retention times of about 25 minutes and about 52 minutes, and those components that do not change in peak height and area before and after the treatment, are also subjected to the water dispersibility improvement treatment of the present invention. It was confirmed that it was not affected.
  • the average mass of the adhered residue is 0.1 l lg, and this amount corresponds to a little over 7% as the propolis component.
  • the average amount of adhering residue in the cup is 0.002 g, indicating that there is virtually no adhering residue. confirmed. It was confirmed that the slight adhesion residue at this time can be easily removed by hand washing with running water.
  • the water dispersibility-improved propolis extract A does not impair its good water dispersibility even when dripped not only in water but also in green tea, black tea, and the like.
  • the components do not sink even if the residual alcohol content is reduced by, for example, decompression or heating after addition to beverages or water. It has been found that the water dispersibility-improved provolis extract of the present invention can also be applied to the field of non-alcoholic beverages and the like in which the above problems are problematic.
  • the disadvantages of a propolis having a number of excellent properties are the disadvantages of adhesion to containers, oral cavity and throat, and difficulty in improving flavor. It can be remarkably improved without using milk protein or the like. For this reason, the water dispersibility-improved propolis extract according to the present invention can be easily applied to the food and beverage fields, which have been difficult to apply, as well as the fields where the conventional propolis extract is used.

Abstract

L'objectif de l'invention est de créer un procédé permettant de supprimer les inconvénients liés au propolis, à savoir un procédé permettant de réduire l'adhérence à un contenant, à l'intérieur de la cavité orale et de la gorge et de faciliter le renforcement de la saveur, avec d'excellentes performances, sans recourir à des substances risquant de compromettre l'absorption de la protéine de lait, etc., et de créer un extrait de propolis à dispersibilité dans l'eau améliorée, ne présentant pas les inconvénients mentionnés plus haut. Cet objectif est atteint au moyen d'un extrait de propolis à dispersibilité dans l'eau améliorée, produit par chauffage d'un extrait de propolis obtenu par extraction d'alcool en présence de carbonate de sodium et/ou d'hydrogénocarbonate de sodium.
PCT/JP2004/018163 2004-12-06 2004-12-06 Extrait de propolis a dispersibilite dans l'eau amelioree, boisson contenant du propolis, et procede visant a ameliorer la dispersibilite dans l'eau d'un extrait de propolis WO2006061877A1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
PCT/JP2004/018163 WO2006061877A1 (fr) 2004-12-06 2004-12-06 Extrait de propolis a dispersibilite dans l'eau amelioree, boisson contenant du propolis, et procede visant a ameliorer la dispersibilite dans l'eau d'un extrait de propolis
CN2004800445476A CN101083915B (zh) 2004-12-06 2004-12-06 水分散性改良的蜂胶提取物、含蜂胶的饮料以及蜂胶提取物的水分散性改良方法
TW093140567A TW200621169A (en) 2004-12-06 2004-12-24 Propolis extract with improved water dispersibility, propolis-containing beverage, and method of improving water dispersibility of propolis extract

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP2004/018163 WO2006061877A1 (fr) 2004-12-06 2004-12-06 Extrait de propolis a dispersibilite dans l'eau amelioree, boisson contenant du propolis, et procede visant a ameliorer la dispersibilite dans l'eau d'un extrait de propolis

Publications (1)

Publication Number Publication Date
WO2006061877A1 true WO2006061877A1 (fr) 2006-06-15

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PCT/JP2004/018163 WO2006061877A1 (fr) 2004-12-06 2004-12-06 Extrait de propolis a dispersibilite dans l'eau amelioree, boisson contenant du propolis, et procede visant a ameliorer la dispersibilite dans l'eau d'un extrait de propolis

Country Status (3)

Country Link
CN (1) CN101083915B (fr)
TW (1) TW200621169A (fr)
WO (1) WO2006061877A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014198687A (ja) * 2013-03-29 2014-10-23 ユーハ味覚糖株式会社 抗炎症作用を増強させたプロポリス・ケルセチン含有組成物
GR20170100541A (el) * 2017-11-30 2019-06-20 Γεωργιος Χαραλαμπου Βλαχοπουλος Διαλυμα προπολης σε αποσταγμα στεμφυλων σταφυλης

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105560295A (zh) * 2015-04-08 2016-05-11 王晓丽 一种可用于抑制真菌的蜂胶组合物
CN107198188A (zh) * 2017-06-13 2017-09-26 重庆市畜牧科学院 水溶性蜂胶的制备方法
CN114306390A (zh) * 2022-01-23 2022-04-12 吉林蜂道馆健康产业有限公司 一种降血糖的蜂疗产品的制备方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60262585A (ja) * 1984-06-09 1985-12-25 Maruzen Shokuhin Kogyo Kk そば茶の製造方法
JPH08173043A (ja) * 1994-12-22 1996-07-09 Yunikafue:Kk 風味を改良した水溶性コーヒーとその製造方法と風味を改良した水溶性コーヒー飲料とその製造方法と風味を改良したインスタント・コーヒーとその製造方法と風味を改良したコーヒーの保存飲料とその製造方法と風味を改良したブラックコーヒーとその製造方法と風味を改良したコーヒーの応用食品とその製造方法
JPH10327827A (ja) * 1997-06-04 1998-12-15 Api Kk プロポリスエキス含有飲料及びその製造方法
JP2004149415A (ja) * 2002-10-28 2004-05-27 Tokyo Trading & Co Ltd プロポリス抽出物の製造方法及びプロポリス抽出物

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60262585A (ja) * 1984-06-09 1985-12-25 Maruzen Shokuhin Kogyo Kk そば茶の製造方法
JPH08173043A (ja) * 1994-12-22 1996-07-09 Yunikafue:Kk 風味を改良した水溶性コーヒーとその製造方法と風味を改良した水溶性コーヒー飲料とその製造方法と風味を改良したインスタント・コーヒーとその製造方法と風味を改良したコーヒーの保存飲料とその製造方法と風味を改良したブラックコーヒーとその製造方法と風味を改良したコーヒーの応用食品とその製造方法
JPH10327827A (ja) * 1997-06-04 1998-12-15 Api Kk プロポリスエキス含有飲料及びその製造方法
JP2004149415A (ja) * 2002-10-28 2004-05-27 Tokyo Trading & Co Ltd プロポリス抽出物の製造方法及びプロポリス抽出物

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014198687A (ja) * 2013-03-29 2014-10-23 ユーハ味覚糖株式会社 抗炎症作用を増強させたプロポリス・ケルセチン含有組成物
GR20170100541A (el) * 2017-11-30 2019-06-20 Γεωργιος Χαραλαμπου Βλαχοπουλος Διαλυμα προπολης σε αποσταγμα στεμφυλων σταφυλης
GR1009611B (el) * 2017-11-30 2019-10-08 Γεωργιος Χαραλαμπου Βλαχοπουλος Διαλυμα προπολης σε αποσταγμα στεμφυλων σταφυλης

Also Published As

Publication number Publication date
CN101083915A (zh) 2007-12-05
CN101083915B (zh) 2010-04-28
TW200621169A (en) 2006-07-01

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