WO2003090775A1 - Produits alimentaires et medicaments contenant de la poudre de soie de ver a soie et de ver a soie sauvage permettant de lutter contre la demence et d'ameliorer l'apprentissage par memorisation - Google Patents

Produits alimentaires et medicaments contenant de la poudre de soie de ver a soie et de ver a soie sauvage permettant de lutter contre la demence et d'ameliorer l'apprentissage par memorisation Download PDF

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Publication number
WO2003090775A1
WO2003090775A1 PCT/JP2002/009051 JP0209051W WO03090775A1 WO 2003090775 A1 WO2003090775 A1 WO 2003090775A1 JP 0209051 W JP0209051 W JP 0209051W WO 03090775 A1 WO03090775 A1 WO 03090775A1
Authority
WO
WIPO (PCT)
Prior art keywords
silkworms
wild
silkworm
silk powder
learning
Prior art date
Application number
PCT/JP2002/009051
Other languages
English (en)
Japanese (ja)
Inventor
Kenjiro Hamashima
Koichi Suzuki
Keiichiro Yamamoto
Junko Ohuchi
Original Assignee
Heart Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Heart Co., Ltd. filed Critical Heart Co., Ltd.
Priority to AU2002332302A priority Critical patent/AU2002332302A1/en
Publication of WO2003090775A1 publication Critical patent/WO2003090775A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/01—Hydrolysed proteins; Derivatives thereof
    • A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Definitions

  • the present invention relates to a method for improving the anti-dementia effect and the memory learning effect of mammals including humans.
  • Silkworm and silkworm silk powders are pulverized by various manufacturing techniques, and the amino acid composition of the low molecular weight pulverized protein is a known amino acid composition because it is a protein at the mouth of the fiber. It is used for foods and cosmetics as its usage.
  • amino acids constituting the protein of the fibular mouth such as glycine, alanine, serine, and tyrosine are abundant, anti-dementia effects and memory learning improvement effects are expected for silkworms and silkworm wild silkworms.
  • Silkworms and wild silkworm silk powder prepared according to known production methods were allowed to freely ingest mice (five-week-old ICR female) orally as an aqueous solution, and tap water was used as a control.
  • Serum albumin (adopted as brush-po) Oral administration of aqueous solution. Disclosure of the invention
  • Fig. 1 This is the result of performing a step-through passive avoidance experiment for two days 30 days after the start of ingestion.
  • scopolamine which causes temporary dementia
  • reproduction the time until the door is opened and a dark room is measured.
  • data analysis is performed using nonparametric analysis. Tests within the same county use the Wilcoxon signed rank test, and tests between different groups use the Mann-Whitney U test to find significant differences.
  • the example shown in FIG. 1 is the result of the memory ability (sec) in the acquisition trial, the scopol amine administration trial, and the regeneration trial.

Abstract

La présente invention concerne un procédé pour clarifier des poudres de soie de ver à soie et de ver à soie sauvage qui permettent de lutter contre la démence et d'améliorer l'apprentissage par mémorisation. Selon cette invention, des produits alimentaires et des médicaments contenant des poudres de soie de ver à soie et de ver à soie sauvage sont administrés à des mammifères, notamment à des êtres humains.
PCT/JP2002/009051 2002-04-24 2002-09-05 Produits alimentaires et medicaments contenant de la poudre de soie de ver a soie et de ver a soie sauvage permettant de lutter contre la demence et d'ameliorer l'apprentissage par memorisation WO2003090775A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002332302A AU2002332302A1 (en) 2002-04-24 2002-09-05 Foods and drugs containing silkworm and wild silkworm silk powder for antidementia effect and improving memorization learning

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2002-158295 2002-04-24
JP2002158295A JP2003310211A (ja) 2002-04-24 2002-04-24 カイコおよび野蚕のシルクパウダーを含有させ抗痴呆効果ならびに記憶学習向上を目的とする食品および医薬品

Publications (1)

Publication Number Publication Date
WO2003090775A1 true WO2003090775A1 (fr) 2003-11-06

Family

ID=29267853

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2002/009051 WO2003090775A1 (fr) 2002-04-24 2002-09-05 Produits alimentaires et medicaments contenant de la poudre de soie de ver a soie et de ver a soie sauvage permettant de lutter contre la demence et d'ameliorer l'apprentissage par memorisation

Country Status (3)

Country Link
JP (1) JP2003310211A (fr)
AU (1) AU2002332302A1 (fr)
WO (1) WO2003090775A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006014033A1 (fr) 2004-07-31 2006-02-09 Brainguard Co., Ltd. Peptide de soie ameliorant les effets neuroprotecteurs et neurofonctionnels et methode de preparation

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009280503A (ja) * 2008-05-19 2009-12-03 Iwate Univ クリキュラトリフェネストラータの繭の薬理用途
JP2012017287A (ja) * 2010-07-07 2012-01-26 Iwate Univ 老齢性疾患治療薬
JP2012040010A (ja) * 2011-09-14 2012-03-01 Biogrand Co Ltd 組成物の食品または機能性食品に対する添加剤としての使用
KR102092586B1 (ko) * 2018-05-23 2020-03-24 대한민국(농촌진흥청장) 견사단백질을 갖는 익힌 누에가공물을 함유하는 기억력 개선용 조성물 또는, 알츠하이머성 치매 예방 및 치료용 조성물

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04267861A (ja) * 1991-02-19 1992-09-24 Nagahama Sangyo Kk シルクパウダー入りドレッシングおよびその製造方法
JP2000093091A (ja) * 1998-09-25 2000-04-04 Gakuei O 野蚕水溶性シルクパウダ−およびその製造方法
JP2000201643A (ja) * 1999-01-11 2000-07-25 Eiko:Kk 絹蛋白質加水分解物を添加した梅干し及びその製造方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04267861A (ja) * 1991-02-19 1992-09-24 Nagahama Sangyo Kk シルクパウダー入りドレッシングおよびその製造方法
JP2000093091A (ja) * 1998-09-25 2000-04-04 Gakuei O 野蚕水溶性シルクパウダ−およびその製造方法
JP2000201643A (ja) * 1999-01-11 2000-07-25 Eiko:Kk 絹蛋白質加水分解物を添加した梅干し及びその製造方法

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006014033A1 (fr) 2004-07-31 2006-02-09 Brainguard Co., Ltd. Peptide de soie ameliorant les effets neuroprotecteurs et neurofonctionnels et methode de preparation
EP1773864A1 (fr) * 2004-07-31 2007-04-18 Biogrand Co., Ltd. Peptide de soie ameliorant les effets neuroprotecteurs et neurofonctionnels et methode de preparation
EP1773864A4 (fr) * 2004-07-31 2009-02-18 Biogrand Co Ltd Peptide de soie ameliorant les effets neuroprotecteurs et neurofonctionnels et methode de preparation
AU2004322006B2 (en) * 2004-07-31 2012-05-24 Brainguard Co., Ltd. Silk peptide improving neuroprotective and neurofunctional effects and a method of its preparation

Also Published As

Publication number Publication date
JP2003310211A (ja) 2003-11-05
AU2002332302A1 (en) 2003-11-10

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