WO2001001967A1 - Mikroreservoirsystem auf basis von polysiloxanen und ambiphilen lösemitteln - Google Patents
Mikroreservoirsystem auf basis von polysiloxanen und ambiphilen lösemitteln Download PDFInfo
- Publication number
- WO2001001967A1 WO2001001967A1 PCT/EP2000/005658 EP0005658W WO0101967A1 WO 2001001967 A1 WO2001001967 A1 WO 2001001967A1 EP 0005658 W EP0005658 W EP 0005658W WO 0101967 A1 WO0101967 A1 WO 0101967A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- solvent
- transdermal therapeutic
- therapeutic system
- ambiphilic
- microreservoirs
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs
Abstract
Description
Claims
Priority Applications (18)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL352361A PL197492B1 (pl) | 1999-07-02 | 2000-06-20 | Transdermalny system terapeutyczny zawierający warstwę polimerową z zawartymi w niej mikrozbiornikami i sposób wytwarzania błon |
MXPA02000118A MXPA02000118A (es) | 1999-07-02 | 2000-06-20 | Sistema de microdepositos a base de polisiloxanos y solventes ambifilos. |
NZ515953A NZ515953A (en) | 1999-07-02 | 2000-06-20 | Microreservoir system on the basis of polysiloxanes and ambiphilic solvents |
EP00936897A EP1191927B1 (de) | 1999-07-02 | 2000-06-20 | Mikroreservoirsystem auf basis von polysiloxanen und ambiphilen lösemitteln |
BR0012152-5A BR0012152A (pt) | 1999-07-02 | 2000-06-20 | Sistema de microrreservatórios na base de polissiloxanos e solventes ambifìlicos |
DK00936897T DK1191927T3 (da) | 1999-07-02 | 2000-06-20 | Mikroreservoirsystem på basis af polysiloxaner og ambifile opløsningsmidler |
HU0201763A HU229085B1 (en) | 1999-07-02 | 2000-06-20 | Microreservoir system on the basis of polysiloxanes and ambiphilic solvents |
AU52220/00A AU774740B2 (en) | 1999-07-02 | 2000-06-20 | Microreservoir system on the basis of polysiloxanes and ambiphilic solvents |
CA002374930A CA2374930C (en) | 1999-07-02 | 2000-06-20 | Microreservoir system based on polysiloxanes and ambiphilic solvents |
DE2000501450 DE122006000008I1 (de) | 1999-07-02 | 2000-06-20 | Mikroreservoirsystem auf basis von Polysiloxanen und Ambiphilen L¦semitteln |
DE50001450T DE50001450D1 (de) | 1999-07-02 | 2000-06-20 | Mikroreservoirsystem auf basis von polysiloxanen und ambiphilen lösemitteln |
AT00936897T ATE234081T1 (de) | 1999-07-02 | 2000-06-20 | Mikroreservoirsystem auf basis von polysiloxanen und ambiphilen lösemitteln |
IL14724700A IL147247A0 (en) | 1999-07-02 | 2000-06-20 | Microreservoir system based on polysiloxanes and ambiphilic solvents |
JP2001507462A JP4428899B2 (ja) | 1999-07-02 | 2000-06-20 | ポリシロキサンおよび両親和性溶媒を基にした微小貯蔵所系 |
IL147247A IL147247A (en) | 1999-07-02 | 2001-12-23 | The mikveh micro-system is based on polysiloxanes and ambiphilic solvents |
HK02108681.5A HK1047234B (zh) | 1999-07-02 | 2002-11-29 | 以聚硅氧烷及親兩性溶劑為基礎的微貯存系統 |
US10/835,997 US10532033B2 (en) | 1999-07-02 | 2004-04-29 | Microreservoir system based on polysiloxanes and ambiphilic solvents |
US16/653,540 US10709669B2 (en) | 1999-07-02 | 2019-10-15 | Microreservoir system based on polysiloxanes and ambiphilic solvents |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19930340.1 | 1999-07-02 | ||
DE19930340 | 1999-07-02 | ||
DE19958554.7 | 1999-12-04 | ||
DE19958554A DE19958554C2 (de) | 1999-07-02 | 1999-12-04 | Mikroreservoirsystem auf Basis von Polysiloxanen und ambiphilen Lösemitteln und ihre Herstellung |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10019378 A-371-Of-International | 2001-12-27 | ||
US10/835,997 Continuation US10532033B2 (en) | 1999-07-02 | 2004-04-29 | Microreservoir system based on polysiloxanes and ambiphilic solvents |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2001001967A1 true WO2001001967A1 (de) | 2001-01-11 |
Family
ID=26054014
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2000/005658 WO2001001967A1 (de) | 1999-07-02 | 2000-06-20 | Mikroreservoirsystem auf basis von polysiloxanen und ambiphilen lösemitteln |
Country Status (22)
Country | Link |
---|---|
US (2) | US10532033B2 (de) |
EP (1) | EP1191927B1 (de) |
JP (1) | JP4428899B2 (de) |
CN (1) | CN1195505C (de) |
AT (1) | ATE234081T1 (de) |
AU (1) | AU774740B2 (de) |
BR (1) | BR0012152A (de) |
CA (1) | CA2374930C (de) |
CZ (1) | CZ301726B6 (de) |
DK (1) | DK1191927T3 (de) |
ES (1) | ES2194736T3 (de) |
HK (1) | HK1047234B (de) |
HU (1) | HU229085B1 (de) |
IL (1) | IL147247A0 (de) |
MX (1) | MXPA02000118A (de) |
NZ (1) | NZ515953A (de) |
PL (1) | PL197492B1 (de) |
PT (1) | PT1191927E (de) |
RU (1) | RU2263502C2 (de) |
TR (1) | TR200103845T2 (de) |
TW (2) | TWI255723B (de) |
WO (1) | WO2001001967A1 (de) |
Cited By (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003018071A1 (de) * | 2001-08-24 | 2003-03-06 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches system (tts) mit dem wirkstoff fentanyl |
US20080026043A1 (en) * | 2004-09-13 | 2008-01-31 | Walter Mueller | Transdermal Therapeutic System Comprising an Adhesive Layer Method for Siliconizing the Back Layer or the System and Use of Said Back Layer |
EP1906943A1 (de) * | 2005-07-22 | 2008-04-09 | Sang-Cheol Chi | Transdermales pflaster mit paroxetin |
WO2008061677A1 (de) * | 2006-11-21 | 2008-05-29 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches system mit ionenpaar-mikroreservoiren |
WO2013098390A1 (de) | 2011-12-30 | 2013-07-04 | Ucb Pharma Gmbh | Transdermales therapeutisches system mit geringer neigung zur spontankristallisation |
US8821920B2 (en) | 2003-04-14 | 2014-09-02 | Lts Lohmann Therapie Systeme Ag | Therapeutic patch for transdermal delivery of capsaicin |
EP2946776A1 (de) | 2014-05-20 | 2015-11-25 | LTS LOHMANN Therapie-Systeme AG | Transdermales therapeutisches System zur Abgabe von Amitriptylin |
WO2015177212A1 (en) * | 2014-05-20 | 2015-11-26 | Lts Lohmann Therapie-Systeme Ag | Transdermal delivery system including an interface mediator |
US9308202B2 (en) | 2006-11-21 | 2016-04-12 | Purdue Pharma L.P. | Transdermal therapeutic system for administering the active substance buprenorphine |
US9549903B2 (en) | 2011-12-12 | 2017-01-24 | Purdue Pharma L.P. | Transdermal delivery system comprising buprenorphine |
US11033723B2 (en) | 2013-07-03 | 2021-06-15 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system comprising an electronic component |
US11389410B2 (en) | 2012-11-22 | 2022-07-19 | Lts Lohmann Therapie-Systeme Ag | Multi-day patch for the transdermal administration of rotigotine |
US11426359B2 (en) | 2014-05-20 | 2022-08-30 | Lts Lohmann Therapie-Systeme Ag | Method for adjusting the release of active agent in a transdermal delivery system |
US11529345B2 (en) | 2013-06-04 | 2022-12-20 | Lts Lohmann Therapie-Systeme Ag | Buprenorphine transdermal delivery system |
US11633367B2 (en) | 2014-05-20 | 2023-04-25 | Lts Lohmann Therapie-Systeme Ag | Transdermal delivery system containing rotigotine |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU229085B1 (en) | 1999-07-02 | 2013-07-29 | Lohmann Therapie Syst Lts | Microreservoir system on the basis of polysiloxanes and ambiphilic solvents |
US8246980B2 (en) * | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system |
DE102007041557B4 (de) * | 2007-08-29 | 2011-03-31 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System enthaltend längliche Hohlkörper |
BR112020003314A2 (pt) * | 2017-09-04 | 2020-08-25 | Lts Lohmann Therapie-Systeme Ag | sistema de liberação transdérmico incluindo um emulsificante |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1987007138A1 (en) * | 1986-05-30 | 1987-12-03 | Rutgers, The State University Of New Jersey | Transdermal absorption dosage unit for estradiol and other estrogenic steroids and process for administration |
WO1990010425A1 (en) * | 1989-03-08 | 1990-09-20 | Rutgers, The State University Of New Jersey | Transdermal absorption dosage unit for postmenopausal syndrome treatment and process for administration |
WO1994006383A1 (en) * | 1992-09-14 | 1994-03-31 | Rutgers, The State University Of New Jersey | Transdermal controlled delivery of pharmaceuticals at variable dosage rates and processes |
Family Cites Families (24)
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US3854480A (en) | 1969-04-01 | 1974-12-17 | Alza Corp | Drug-delivery system |
GB1361289A (en) | 1971-06-14 | 1974-07-24 | Alza Corp | Bandage for administering drugs |
US3946106A (en) | 1974-10-24 | 1976-03-23 | G. D. Searle & Co. | Microsealed pharmaceutical delivery device |
US4053580A (en) | 1975-01-01 | 1977-10-11 | G. D. Searle & Co. | Microsealed pharmaceutical delivery device |
US4036228A (en) | 1975-09-11 | 1977-07-19 | Alza Corporation | Osmotic dispenser with gas generating means |
DE3333240A1 (de) | 1983-09-12 | 1985-03-28 | Schering AG, 1000 Berlin und 4709 Bergkamen | Mittel zur transdermalen applikation von arzneimittelwirkstoffen |
US4573996A (en) * | 1984-01-03 | 1986-03-04 | Jonergin, Inc. | Device for the administration of an active agent to the skin or mucosa |
EP0196769B1 (de) | 1985-02-25 | 1992-07-08 | Rutgers, The State University of New Jersey | Dosierungssystem für transdermale Absorption von Arzneimittelwirkstoffen |
US4818540A (en) * | 1985-02-25 | 1989-04-04 | Rutgers, The State University Of New Jersey | Transdermal fertility control system and process |
GB8704755D0 (en) | 1987-02-28 | 1987-04-01 | Dow Corning Ltd | Pharmaceutical delivery device |
CH674618A5 (de) * | 1987-04-02 | 1990-06-29 | Ciba Geigy Ag | |
US5446070A (en) * | 1991-02-27 | 1995-08-29 | Nover Pharmaceuticals, Inc. | Compositions and methods for topical administration of pharmaceutically active agents |
US5656286A (en) * | 1988-03-04 | 1997-08-12 | Noven Pharmaceuticals, Inc. | Solubility parameter based drug delivery system and method for altering drug saturation concentration |
EP0370220B1 (de) | 1988-10-27 | 1996-01-10 | Schering Aktiengesellschaft | Mittel zur transdermalen Applikation enthaltend Gestoden |
DE3910578A1 (de) | 1989-03-29 | 1990-10-04 | Schering Ag | Mittel zur transdermalen applikation enthaltend gestoden |
DE4336557C2 (de) | 1993-05-06 | 1997-07-17 | Lohmann Therapie Syst Lts | Estradiolhaltiges transdermales therapeutisches System, Verfahren zu seiner Herstellung und seine Verwendung |
DE4332093C2 (de) | 1993-09-22 | 1995-07-13 | Lohmann Therapie Syst Lts | Transdermales therapeutisches System mit dem Wirkstoff Acetylsalicylsäure und Verfahren zu seiner Herstellung |
US5688523A (en) * | 1995-03-31 | 1997-11-18 | Minnesota Mining And Manufacturing Company | Method of making a pressure sensitive skin adhesive sheet material |
US5906830A (en) * | 1995-09-08 | 1999-05-25 | Cygnus, Inc. | Supersaturated transdermal drug delivery systems, and methods for manufacturing the same |
FR2740038B1 (fr) | 1995-10-20 | 1998-01-02 | Lafon Labor | Composition pour l'administration transdermique |
DE19814084B4 (de) | 1998-03-30 | 2005-12-22 | Lts Lohmann Therapie-Systeme Ag | D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung |
US6381852B1 (en) | 1998-08-17 | 2002-05-07 | Dart Industries, Inc. | Pastry cutter set with combined storage case and support |
HUP9802963A1 (hu) | 1998-12-18 | 2000-12-28 | József Bereznai | Szagelszívás közvetlen a WC-csészéből és az ezt biztosító szerkezet |
HU229085B1 (en) | 1999-07-02 | 2013-07-29 | Lohmann Therapie Syst Lts | Microreservoir system on the basis of polysiloxanes and ambiphilic solvents |
-
2000
- 2000-06-20 HU HU0201763A patent/HU229085B1/hu unknown
- 2000-06-20 BR BR0012152-5A patent/BR0012152A/pt not_active Application Discontinuation
- 2000-06-20 CN CNB008092028A patent/CN1195505C/zh not_active Expired - Lifetime
- 2000-06-20 PL PL352361A patent/PL197492B1/pl unknown
- 2000-06-20 AT AT00936897T patent/ATE234081T1/de active
- 2000-06-20 TR TR2001/03845T patent/TR200103845T2/xx unknown
- 2000-06-20 NZ NZ515953A patent/NZ515953A/xx not_active IP Right Cessation
- 2000-06-20 PT PT00936897T patent/PT1191927E/pt unknown
- 2000-06-20 AU AU52220/00A patent/AU774740B2/en not_active Expired
- 2000-06-20 CA CA002374930A patent/CA2374930C/en not_active Expired - Lifetime
- 2000-06-20 MX MXPA02000118A patent/MXPA02000118A/es active IP Right Grant
- 2000-06-20 EP EP00936897A patent/EP1191927B1/de not_active Expired - Lifetime
- 2000-06-20 IL IL14724700A patent/IL147247A0/xx active IP Right Grant
- 2000-06-20 WO PCT/EP2000/005658 patent/WO2001001967A1/de active IP Right Grant
- 2000-06-20 DK DK00936897T patent/DK1191927T3/da active
- 2000-06-20 CZ CZ20014514A patent/CZ301726B6/cs not_active IP Right Cessation
- 2000-06-20 ES ES00936897T patent/ES2194736T3/es not_active Expired - Lifetime
- 2000-06-20 RU RU2002102869/15A patent/RU2263502C2/ru active
- 2000-06-20 JP JP2001507462A patent/JP4428899B2/ja not_active Expired - Fee Related
- 2000-06-29 TW TW089112896A patent/TWI255723B/zh not_active IP Right Cessation
- 2000-06-29 TW TW093123098A patent/TWI256311B/zh not_active IP Right Cessation
-
2002
- 2002-11-29 HK HK02108681.5A patent/HK1047234B/zh not_active IP Right Cessation
-
2004
- 2004-04-29 US US10/835,997 patent/US10532033B2/en not_active Expired - Fee Related
-
2019
- 2019-10-15 US US16/653,540 patent/US10709669B2/en not_active Expired - Lifetime
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1987007138A1 (en) * | 1986-05-30 | 1987-12-03 | Rutgers, The State University Of New Jersey | Transdermal absorption dosage unit for estradiol and other estrogenic steroids and process for administration |
WO1990010425A1 (en) * | 1989-03-08 | 1990-09-20 | Rutgers, The State University Of New Jersey | Transdermal absorption dosage unit for postmenopausal syndrome treatment and process for administration |
WO1994006383A1 (en) * | 1992-09-14 | 1994-03-31 | Rutgers, The State University Of New Jersey | Transdermal controlled delivery of pharmaceuticals at variable dosage rates and processes |
Cited By (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7390500B2 (en) | 2001-08-24 | 2008-06-24 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system (TTS) with fentanyl as a active ingredient |
JP2005501865A (ja) * | 2001-08-24 | 2005-01-20 | エルテーエス ローマン テラピー−ジステーメ アーゲー | 活性成分フェンタニルを含む経皮治療システム(tts) |
DE10141651B4 (de) * | 2001-08-24 | 2007-02-15 | Lts Lohmann Therapie-Systeme Ag | Transdermales Therapeutisches System (TTS) mit dem Wirkstoff Fentanyl und Verfahren zu seiner Herstellung |
WO2003018071A1 (de) * | 2001-08-24 | 2003-03-06 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches system (tts) mit dem wirkstoff fentanyl |
KR100895188B1 (ko) * | 2001-08-24 | 2009-04-24 | 에르테에스 로만 테라피-시스테메 아게 | 활성성분으로서 펜타닐을 함유하는 경피치료 시스템 |
CN100438859C (zh) * | 2001-08-24 | 2008-12-03 | Lts勒曼治疗系统股份公司 | 含有活性物质芬太尼的透皮治疗体系(tts) |
US8821920B2 (en) | 2003-04-14 | 2014-09-02 | Lts Lohmann Therapie Systeme Ag | Therapeutic patch for transdermal delivery of capsaicin |
US9226903B2 (en) * | 2004-09-13 | 2016-01-05 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system comprising an adhesive layer method for siliconizing the back layer or the system and use of said back layer |
US10034841B2 (en) | 2004-09-13 | 2018-07-31 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system comprising an adhesive layer method for siliconizing the back layer of the system and use of said back layer |
US20080026043A1 (en) * | 2004-09-13 | 2008-01-31 | Walter Mueller | Transdermal Therapeutic System Comprising an Adhesive Layer Method for Siliconizing the Back Layer or the System and Use of Said Back Layer |
EP1906943A1 (de) * | 2005-07-22 | 2008-04-09 | Sang-Cheol Chi | Transdermales pflaster mit paroxetin |
EP1906943A4 (de) * | 2005-07-22 | 2012-01-18 | Iksu Pharmaceutical Co Ltd | Transdermales pflaster mit paroxetin |
WO2008061677A1 (de) * | 2006-11-21 | 2008-05-29 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches system mit ionenpaar-mikroreservoiren |
US9089527B2 (en) | 2006-11-21 | 2015-07-28 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system comprising ion pair microreservoirs |
US9308202B2 (en) | 2006-11-21 | 2016-04-12 | Purdue Pharma L.P. | Transdermal therapeutic system for administering the active substance buprenorphine |
US9549903B2 (en) | 2011-12-12 | 2017-01-24 | Purdue Pharma L.P. | Transdermal delivery system comprising buprenorphine |
DE102011090178A1 (de) | 2011-12-30 | 2013-07-04 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System mit geringer Neigung zur Spontankristallisation |
WO2013098390A1 (de) | 2011-12-30 | 2013-07-04 | Ucb Pharma Gmbh | Transdermales therapeutisches system mit geringer neigung zur spontankristallisation |
US11389410B2 (en) | 2012-11-22 | 2022-07-19 | Lts Lohmann Therapie-Systeme Ag | Multi-day patch for the transdermal administration of rotigotine |
US11529345B2 (en) | 2013-06-04 | 2022-12-20 | Lts Lohmann Therapie-Systeme Ag | Buprenorphine transdermal delivery system |
US11033723B2 (en) | 2013-07-03 | 2021-06-15 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system comprising an electronic component |
WO2015177212A1 (en) * | 2014-05-20 | 2015-11-26 | Lts Lohmann Therapie-Systeme Ag | Transdermal delivery system including an interface mediator |
EP2946776A1 (de) | 2014-05-20 | 2015-11-25 | LTS LOHMANN Therapie-Systeme AG | Transdermales therapeutisches System zur Abgabe von Amitriptylin |
US11426359B2 (en) | 2014-05-20 | 2022-08-30 | Lts Lohmann Therapie-Systeme Ag | Method for adjusting the release of active agent in a transdermal delivery system |
US11633367B2 (en) | 2014-05-20 | 2023-04-25 | Lts Lohmann Therapie-Systeme Ag | Transdermal delivery system containing rotigotine |
US11752110B2 (en) | 2014-05-20 | 2023-09-12 | Lts Lohmann Therapie-Systeme Ag | Transdermal delivery system including an interface mediator |
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