WO1997049387A1 - Particles comprising amphiphilic copolymers, having a cross-linked shell domain and an interior core domain, useful for pharmaceutical and other applications - Google Patents
Particles comprising amphiphilic copolymers, having a cross-linked shell domain and an interior core domain, useful for pharmaceutical and other applications Download PDFInfo
- Publication number
- WO1997049387A1 WO1997049387A1 PCT/US1997/011345 US9711345W WO9749387A1 WO 1997049387 A1 WO1997049387 A1 WO 1997049387A1 US 9711345 W US9711345 W US 9711345W WO 9749387 A1 WO9749387 A1 WO 9749387A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- poly
- particle
- particles
- domain
- acid
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5138—Organic macromolecular compounds; Dendrimers obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/24—Crosslinking, e.g. vulcanising, of macromolecules
- C08J3/246—Intercrosslinking of at least two polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2991—Coated
- Y10T428/2998—Coated including synthetic resin or polymer
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP50359098A JP2001508762A (ja) | 1996-06-27 | 1997-06-27 | 架橋した外殻領域および内部芯領域を有する両親媒性コポリマーからなり、医薬およびその他の用途に有用な粒子 |
EP97932378A EP0910351A1 (en) | 1996-06-27 | 1997-06-27 | Particles comprising amphiphilic copolymers, having a cross-linked shell domain and an interior core domain, useful for pharmaceutical and other applications |
AU35853/97A AU3585397A (en) | 1996-06-27 | 1997-06-27 | Particles comprising amphiphilic copolymers, having a cross-linked shell domain and an interior core domain, useful for pharmaceutical and other applications |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2069396P | 1996-06-27 | 1996-06-27 | |
US60/020,693 | 1996-06-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1997049387A1 true WO1997049387A1 (en) | 1997-12-31 |
Family
ID=21800036
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1997/011610 WO1997049736A2 (en) | 1996-06-27 | 1997-06-27 | Particles comprising amphiphilic copolymers, having a cross-linked shell domain and an interior core domain, useful for pharmaceutical and other applications |
PCT/US1997/011345 WO1997049387A1 (en) | 1996-06-27 | 1997-06-27 | Particles comprising amphiphilic copolymers, having a cross-linked shell domain and an interior core domain, useful for pharmaceutical and other applications |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1997/011610 WO1997049736A2 (en) | 1996-06-27 | 1997-06-27 | Particles comprising amphiphilic copolymers, having a cross-linked shell domain and an interior core domain, useful for pharmaceutical and other applications |
Country Status (6)
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WO2003066712A1 (en) * | 2002-02-05 | 2003-08-14 | Rohm And Haas Company | Method for preparation of block copolymeric nanoparticles |
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WO2003078049A1 (en) * | 2002-03-20 | 2003-09-25 | Rhodia Inc. | Vesicles comprising an amphiphilic di-block copolymer and a hydrophobic compound. |
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Publication number | Publication date |
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EP0910351A1 (en) | 1999-04-28 |
JP2001508762A (ja) | 2001-07-03 |
US6491903B1 (en) | 2002-12-10 |
WO1997049736A3 (en) | 1998-02-05 |
AU3585397A (en) | 1998-01-14 |
EP0907666A1 (en) | 1999-04-14 |
CA2258744A1 (en) | 1997-12-31 |
WO1997049736A2 (en) | 1997-12-31 |
AU3649697A (en) | 1998-01-14 |
JP2000514791A (ja) | 2000-11-07 |
US6383500B1 (en) | 2002-05-07 |
CA2258851A1 (en) | 1997-12-31 |
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