WO1994012279A1 - Dispositif de manipulation et de transfert de pointes de pipette - Google Patents

Dispositif de manipulation et de transfert de pointes de pipette Download PDF

Info

Publication number
WO1994012279A1
WO1994012279A1 PCT/DE1993/001062 DE9301062W WO9412279A1 WO 1994012279 A1 WO1994012279 A1 WO 1994012279A1 DE 9301062 W DE9301062 W DE 9301062W WO 9412279 A1 WO9412279 A1 WO 9412279A1
Authority
WO
WIPO (PCT)
Prior art keywords
transfer body
receiving pins
pipette tips
indicates
cover
Prior art date
Application number
PCT/DE1993/001062
Other languages
German (de)
English (en)
Inventor
Bernd Steinbrenner
Original Assignee
Technic Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19924240315 external-priority patent/DE4240315A1/de
Priority claimed from DE4316941A external-priority patent/DE4316941C2/de
Application filed by Technic Limited filed Critical Technic Limited
Publication of WO1994012279A1 publication Critical patent/WO1994012279A1/fr

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/54—Supports specially adapted for pipettes and burettes
    • B01L9/543—Supports specially adapted for pipettes and burettes for disposable pipette tips, e.g. racks or cassettes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/025—Align devices or objects to ensure defined positions relative to each other
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/028—Modular arrangements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0609—Holders integrated in container to position an object
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027—General features of the devices
    • G01N2035/103—General features of the devices using disposable tips

Definitions

  • the invention relates to a device for handling or converting pipette tips, with a preferably similarly plate-shaped conversion body and on one side orthogonally projecting receiving pins, the receiving pins in a predetermined grid, i.e. in a predetermined number and arrangement, provided and shaped in such a way that they fit into the connection-side ends of the pipette tips for their preferably loose receptacle.
  • pipettes which are designed with a narrowing tip.
  • the tips of the pipettes are used in the form of exchangeable plastic pipette tips, which are exchanged and thrown away after a single use.
  • pipette tips of the type in question are always supplied in bulk as disposable articles and are usually autoclaved by the user before they are actually used.
  • autoclavable containers with a perforated plate in which a number of pipette tips are held in such a way that they can be removed without touching the hand by simply plugging them onto the pipette.
  • the entire container ie the container with the perforated plate therein and the inserted pipette tips, is treated in an autoclave.
  • the containers in question come onto the market with the pipette tips already inserted. If the resulting supply of pipette tips has been used up, the known containers offer the option of fitting the perforated plate of the container again - by hand - with pipette tips which are offered and sold loose in bags.
  • the perforated plate is connected in one piece to the container walls.
  • An alternative design is known from EP-A-0 174 706, according to which the perforated plate is designed as a part that can be detached from the container, so that it can be removed from the container, the container after another has been removed from the perforated plate Use can be supplied.
  • the container is usually thrown away in practice.
  • a device for providing sterilized pipette tips which has a multiple autoclavable container, a perforated plate equipped with pipette tips and a folding box.
  • the folding box in turn contains a perforated plate equipped with pipette tips to replace the empty plate in the container after the pipette tips have been used up.
  • the folding box containing the perforated plate with the pipette tips is discarded on the one hand, and the perforated plate on the other hand after removal of the pipette tips, which is also extremely problematic due to the perforated plate made of plastic, particularly with regard to disposal.
  • the present invention is therefore based on the object of specifying a device for handling or converting pipette tips, which is also suitable for transporting, delivering or providing the pipette tips at the same time and with which the pipette tip can be handled easily and quickly ⁇ zen, in particular for the simultaneous implementation of the pipette tips, is possible. Furthermore, it should also be possible with the device according to the invention to quickly and easily move the pipette tips inserted into and supplied in a perforated plate from this perforated plate into a one intended for constant use, i.e. to implement multi-autoclavable perforated plate or box with a corresponding perforated plate, which can then be used in an appropriate container with the inserted pipette tips as a whole.
  • the device according to the invention for handling or converting pipette tips achieves the above object by means of the features of patent claim 1 standing device designed such that it also serves to transport, deliver or provide the pipette tips, namely a cover which can be placed on the transfer body via the pipette tips is provided for this purpose.
  • the device consisting of the transfer body with the receiving pins is designed together with the cover which can be placed thereon in the form of a box, which is used for transport, for delivering or for providing the pipette tips.
  • the conversion body having the receiving pins remains, the receiving pins protruding into the pipette tips and thus carrying them or specifying the grid of the pipette tips.
  • the device according to the invention can also be used in a conventional manner for the basic handling or for converting pipette tips - regardless of the possibility of transport, delivery or provision.
  • the need for a device of the type in question has been recognized here. It has been known that the problem of material disposal associated with the use of pipette tips can be reduced to a very considerable extent by delivering pipette tips in a perforated plate in the usual grid arrangement and the entire packaging material, for example also the perforated plate, made of a recyclable material. Cardboard is particularly suitable for this.
  • the pipette tips inserted into the perforated plate made of cardboard would have to be moved or put into an autoclavable box with an integrated perforated plate or into a perforated plate made of autoclavable material for use in a corresponding box reposition.
  • the pipette tips inserted into the perforated plate according to the grid can be removed from the perforated plate in a single operation in that the conversion body with its orthogonally projecting receiving pins, which are arranged exactly in the grid specified by the perforated plate, from the open End of the pipette tips is moved towards them.
  • the receptacle pins are thus inserted into the pipette tip from the connection-side end thereof, so that the perforated plate can be turned around together with the pipette tips pushed on and the inserted receptacle pins or the entire conversion body, so that the originally inserted into the perforated plate Pipette tips are now seated on the receiving pins or with their ends on the connector body on the transfer body.
  • the perforated plate which is only used for delivery, for example, can be removed from the pipette tips, so that the pipette tips are received by the device according to the invention in the predetermined grid order.
  • a perforated plate which is suitable for autoclaving and can be introduced, for example, into a corresponding box, or is designed as an integral part of a container, with its perforations arranged in a grid-like manner, is pushed over the pipette tips so that after inverting the entire arrangement and removing it of the moving body, ie after pulling out the receptacle mepins, again in a perforated plate, namely in the perforated plate suitable for autoclaving.
  • pipette tips inserted into perforated plates can be moved from one perforated plate to another without touching the pipette tips or even pulling them individually out of one perforated plate and inserting them into the other perforated plate. Consequently, a handling aid is created with the device according to the invention, which enables the handling of pipette tips with the simplest construction and quickly.
  • the device according to the invention thus makes a direct contribution to reducing waste and thus also relieving the environment.
  • the receiving pins it is advantageous if they are cylindrical. To effectively pick up the pipette tip, it is only necessary to ensure that the pick-up pins fit into the pipette tips and come to rest there, possibly with the front end of the pick-up pins.
  • the receiving pins could furthermore have a likewise cylindrical region which widens in at least one step and also fits into the region of the pipette tip which is widened on the connection side, so that a particularly effective reception of the pipette tip is ensured.
  • the receiving pins could taper in several stages, ie discontinuously, towards their free end, so that the receiving pins have a line contact at the edges of the respective stages with the pipette tips, which can be easily released again.
  • the free end of the receiving pins could be made approximately flat, which creates a risk of injury from the device according to the invention, is effectively avoided, particularly in the area of the free ends of the receiving pins.
  • the total of these could roughly be adapted to the inner wall of the pipette tip to be received, so that the receiving pins taper continuously towards the free end.
  • the pick-up pins do not lie against the inner wall when the pipette tip is attached, so that the device according to the invention can be easily removed from the pipette tips reinserted in the perforated plate.
  • the conversion body has pick-up pins on both sides and if the pick-up pins on both sides have different dimensions for picking up pipette tips of different sizes or dimensions. Consequently, the device would be more or less universally usable, namely for holding pipette tips of different sizes.
  • devices of the type according to the invention could be equipped with different "paired" sizes of receiving pins on the two sides of the conversion body. Since the receiving pins on each side are always of the same length, the device according to the invention can be placed almost flat on a flat surface, so it does not pose any problems with regard to storage or storage.
  • the transfer body is rectangular.
  • the device according to the invention or its transfer body is a rectangular plate which should have a tangible thickness for better handling, for example a thickness of approximately one and a half to three centimeters.
  • the transfer body can have a peripheral edge region free of receiving pins, which again favors the handling of the device according to the invention, especially since receiving pins arranged on the outer edge would make it more difficult to grip the device.
  • the peripheral outer edge of the transfer body i.e. the lateral edge area of the repositioning body has formations, depressions, grooves and / or roughened areas for the fingers of a person to be handled. This would ensure that the device according to the invention lies particularly well in the hand and, for example, during handling, i.e. cannot slip out of the hand unintentionally during the transfer of the pipette tips.
  • the receiving pins could be screwed into the conversion body, preferably inserted non-positively and / or glued into it.
  • the transfer body itself could simply be produced from a plate with plane-parallel surfaces, or it could be separated or sawn out of a larger plate.
  • holes arranged in a grid would be arranged in the surrounding are set drilled, so that the receiving pins can be inserted or screwed.
  • the transfer body and the receiving pins are in one piece, i.e. are integral. It is particularly useful to manufacture the transfer body and the receiving pins from plastic, preferably from polypropylene or polycarbonate. The manufacture itself could be carried out in a further advantageous manner by injection molding, which considerably reduces the manufacturing costs, particularly in the case of large quantities.
  • a cover that can be placed on the conversion body via the pipette tips is provided.
  • This cover could be insertable or attachable into or onto the transfer body and / or be latchable with the transfer body. This would ensure that the lid protecting the pipette tips or the lid forming a box together with the transfer body can actually be firmly connected to the transfer body, so that undesired opening is effectively prevented.
  • the transfer body has an insertion groove, preferably formed on the side assigned to the receiving pins, for inserting the cover. In other words, the cover would then be inserted into the transfer body and locked in the insertion groove.
  • the lid would have to be lifted or lifted, for example, at an angle, i.e. be pulled out of the catch.
  • the cover could at least partially encompass the repositioning body, so that it could be latched to the circumferential edge of the repositioning body.
  • Such an embodiment is particularly under manufacturing to be preferred from a technical point of view, since an elaborate groove in the surface of the conversion body is not necessary. Rather, the lid would be put over the transfer body - overall - so that it almost entirely specifies the volume of the box thus formed.
  • the cover in the area of the open end could have projections, lugs or the like protruding inwards, which engage in corresponding recesses on the circumferential edge of the transfer body. In this respect, too, an unwanted opening of the box formed by the transfer body and cover would be largely prevented.
  • the cover removed on the pin side could be connected to the transfer body on the one hand in order to avoid losing it when the pipette tips were exposed, and on the other hand could represent a kind of base or table for the transfer body.
  • the lid could be pulled off again from the side facing away from the receiving pins and in the true sense - i.e. in the sense of a lid - put it back on the side carrying the receiving pins, so that the box formed from the transfer body and lid is closed again.
  • the lid has a handle or carrier.
  • the lid could simply be pulled off by gripping the handle or carrier.
  • the handle or carrier could serve to carry the entire box.
  • the arrangement or box consisting of the repositioning body and cover were designed to be stackable. A stacking could relate to an arrangement one above the other or one below the other or also to a laterally latchable arrangement of different stacks.
  • the transfer body could have a receptacle for the handle or support of the lid on the side facing away from the receiving pins, so that the stackability of the boxes or container is favored by the meshing of the transfer body and handle or support.
  • FIG. 1 shows a side view of an embodiment of a device according to the invention for handling or for transferring pipette tips, the lid forming a box together with the transfer body being placed on the transfer body in the case of existing pipette tips, and
  • FIG. 2 shows the transfer body of the object from FIG. 1 with the cover removed without pipette tips in a top view.
  • 1 shows a device according to the invention for handling or for transferring pipette tips 1.
  • the device has a conversion body 2, which is preferably of a plate-like design, and receiving pins 3 protruding orthogonally on one side of the conversion body 2.
  • the receiving pins 3 are provided in a predetermined grid, ie in a predetermined number and arrangement, and are shaped in such a way that they fit into the connection-side end 4 of the pipette tips 1 for their preferably loose reception.
  • the device according to the invention is designed in such a way that it also serves for the transport, delivery or provision of the pipette tips 1.
  • a cover 5 which can be placed on the transfer body 2 via the pipette tips 1 is provided.
  • Fig. 1 shows particularly clearly that the transfer body 2 together with the lid 5 form a box 6. This box is thus used for transporting or delivering or providing the pipette tips 1, and when the cover 5 is removed, the transfer body 2 can be used in a conventional manner - namely as a transfer body.
  • the receiving pins 3 are cylindrical and, towards the transfer body 2, have a likewise cylindrical region which widens in a step 7 and which fits into the region 8 of the pipette tip 1 which is enlarged on the connection side.
  • Fig. 1 further shows that the free end 9 of the receiving pin 3 is flat.
  • the receiving pins 3 are arranged in an 8 ⁇ 12 grid, that is to say a total of 96 receiving pins 3 with predetermined identical distances from one another.
  • the transfer body 2 is of rectangular design and that it has a peripheral edge region 10 free of receiving pins. This significantly facilitates the handling of the device according to the invention, especially since the edge region 10 has no parts which may interfere with the handling and possibly press in the hand of the operator.
  • the circumferential outer edge 11 of the transfer body 2 could have recesses, grooves and / or roughened areas for the fingers of a handling person for better handling or for securely holding the device according to the invention. For the sake of simplicity, these precautions are not taken into account in the figures.
  • the conversion body 2 and the receiving pins 3 are in one piece, i.e. integral. They are made from plastic, more precisely from a polypropylene or polycarbonate.
  • the entire device according to the invention is produced by injection molding, at least in the embodiment selected here.
  • Fig. 1 further shows particularly clearly that the cover 5 can be plugged onto the transfer body 2 and locked with the transfer body 2.
  • the cover 5 has at least slightly larger internal dimensions than the external dimensions of the transfer body 2, so that the cover 5 partially encompasses the transfer body 2 and can be locked on the peripheral edge 11 of the transfer body 2.
  • the cover 5 in the region of the open end 12 has an inwardly projecting projection 13 or corresponding lugs or the like, which fits into a corresponding recess 14 on the peripheral edge 11 of the Implement body 2 engages.
  • the lid has a handle 15 for handling the lid 5 or for handling the box 6 consisting of the transfer body 2 and lid 5.

Landscapes

  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Devices For Use In Laboratory Experiments (AREA)

Abstract

Un dispositif de manipulation et de transfert de pointes de pipette (1) comporte un corps de transfert (2) de préférence du type plaque, ainsi que des ergots de retenue (3) faisant orthogonalement saillie d'un côté. Ces ergots de retenue (3) sont disposés selon une trame prédéterminée, c.-à-d. selon un nombre et une disposition donnés, et ils ont une forme telle que les extrémités du côté raccordement (4) des pointes de pipettes (1) viennent se placer sur ces ergots de préférence de façon non serrée. Ce dispositif est conçu pour la manipulation simple et rapide de pointes de pipette, en particulier pour en permettre un transfert rapide, cela de sorte qu'il permette également le transport, la fourniture et la mise à disposition des pointes de pipette (1). Ledit dispositif est muni d'un couvercle (5) qui peut être posé par-dessus les pointes de pipette (1), sur le corps de transfert (2).
PCT/DE1993/001062 1992-12-01 1993-11-06 Dispositif de manipulation et de transfert de pointes de pipette WO1994012279A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DEP4240315.4 1992-12-01
DE19924240315 DE4240315A1 (de) 1992-12-01 1992-12-01 Vorrichtung zur Handhabung bzw. zum Umsetzen von Pipettenspitzen
DEP4316941.4 1993-05-21
DE4316941A DE4316941C2 (de) 1992-12-01 1993-05-21 Vorrichtung zur Handhabung bzw. zum Umsetzen von Pipettenspitzen

Publications (1)

Publication Number Publication Date
WO1994012279A1 true WO1994012279A1 (fr) 1994-06-09

Family

ID=25920877

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE1993/001062 WO1994012279A1 (fr) 1992-12-01 1993-11-06 Dispositif de manipulation et de transfert de pointes de pipette

Country Status (1)

Country Link
WO (1) WO1994012279A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0985451A2 (fr) * 1998-09-08 2000-03-15 Labsystems Oy Pack de récharge pour portoir de pointes de pipettes

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2195965A6 (fr) * 1972-08-09 1974-03-08 Medical Laboratory Automation
EP0174706A2 (fr) * 1984-09-14 1986-03-19 Rainin Instrument Co.,Inc. Réceptacle-support pour embouts de pipettes
JPS63194735A (ja) * 1987-02-06 1988-08-11 Inoue Seisakusho:Kk マイクロピペツト用チツプセツト
EP0339557A2 (fr) * 1988-04-25 1989-11-02 Brand GmbH + Co Dispositif pour approvisionner des pipettes stérilisées
DE9307876U1 (fr) * 1992-12-01 1993-07-22 Steinbrenner, Bernd, Dr., 69257 Wiesenbach, De

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2195965A6 (fr) * 1972-08-09 1974-03-08 Medical Laboratory Automation
US3853217A (en) * 1972-08-09 1974-12-10 Medical Laboratory Automation Pipette tip package
EP0174706A2 (fr) * 1984-09-14 1986-03-19 Rainin Instrument Co.,Inc. Réceptacle-support pour embouts de pipettes
JPS63194735A (ja) * 1987-02-06 1988-08-11 Inoue Seisakusho:Kk マイクロピペツト用チツプセツト
EP0339557A2 (fr) * 1988-04-25 1989-11-02 Brand GmbH + Co Dispositif pour approvisionner des pipettes stérilisées
DE9307876U1 (fr) * 1992-12-01 1993-07-22 Steinbrenner, Bernd, Dr., 69257 Wiesenbach, De

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PATENT ABSTRACTS OF JAPAN vol. 12, no. 479 (C - 552)<3326> 14 December 1988 (1988-12-14) *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0985451A2 (fr) * 1998-09-08 2000-03-15 Labsystems Oy Pack de récharge pour portoir de pointes de pipettes
EP0985451A3 (fr) * 1998-09-08 2002-05-15 Labsystems Oy Pack de récharge pour portoir de pointes de pipettes

Similar Documents

Publication Publication Date Title
DE2027006C3 (de) Verpackung für chirurgische Instrumente
EP2210668B1 (fr) Support pour pointes de pipettes
EP0339557B1 (fr) Dispositif pour approvisionner des pipettes stérilisées
DE202006005284U1 (de) Solarzellenbehälter
WO1992001514A1 (fr) Unite de rechargement contenant des pointes de pipettes loges dans une fixation amovible, destinee a un recipient autoclavable
DE4240280C2 (de) Vorrichtung zum Bereitstellen vorzugsweise sterilisierter Pipettenspitzen
DE4434286C1 (de) Verwendung eines plattenförmigen Trägers zur Halterung von einem Stapel Flachdichtungen
WO2013159941A1 (fr) Kit
WO1994012279A1 (fr) Dispositif de manipulation et de transfert de pointes de pipette
DE4316941C2 (de) Vorrichtung zur Handhabung bzw. zum Umsetzen von Pipettenspitzen
EP2163230B1 (fr) Emballage pour dispositif d&#39;aide chirurgical, en particulier pour brosse à pocher de préparation
DE4409411A1 (de) Verpackungsbehälter
DE10251650B4 (de) Behälter zum Aufbewahren und Transportieren von empfindlichen plättchenförmigen Gegenständen und Verwendung eines Solchen
DE4305925C2 (de) Mehrweg-Transportbehälter
DE4240315A1 (de) Vorrichtung zur Handhabung bzw. zum Umsetzen von Pipettenspitzen
CH664094A5 (en) Clip-on lid covers arrayed containers - projecting from apertured carrier plate
DE102010005202B4 (de) Magazin für einen photovoltaischen Wafer- und/oder Zellstapel mit einem Magazineinsatz zur Aufnahme desselben
DE102020114093B4 (de) System von Behältern, insbesondere für Lebensmittel
AT14119U1 (de) Deckel für Müllbehälter
DE3924103A1 (de) Nachfuelleinheit mit in einer loesbaren halterung sitzenden pipettenspitzen fuer einen autoklavierbaren behaelter
EP1654163A1 (fr) Caisson de transport
DE202009014305U1 (de) Medikamentenverteilsystem
DE1486219A1 (de) Tubenbehaelter
DE10159382A1 (de) Transportbehälter für Werkzeuge und/oder Werkstücke
DE8112038U1 (de) Stuelpdeckelschachtel oder dergleichen

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): CA JP US

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LU MC NL PT SE

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: CA