UY32014A - Nuevo procedimiento de obtención de la forma cristalina v de la agomelatina - Google Patents

Nuevo procedimiento de obtención de la forma cristalina v de la agomelatina

Info

Publication number
UY32014A
UY32014A UY0001032014A UY32014A UY32014A UY 32014 A UY32014 A UY 32014A UY 0001032014 A UY0001032014 A UY 0001032014A UY 32014 A UY32014 A UY 32014A UY 32014 A UY32014 A UY 32014A
Authority
UY
Uruguay
Prior art keywords
obtaining
crystalline
agomelatine
new procedure
procedure
Prior art date
Application number
UY0001032014A
Other languages
English (en)
Inventor
Langlois Pascal
Martins Damien
Gerard Coquerel
Linol Julie
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40418877&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UY32014(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Servier Lab filed Critical Servier Lab
Publication of UY32014A publication Critical patent/UY32014A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/18—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/22—Separation; Purification; Stabilisation; Use of additives
    • C07C231/24—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C233/08—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of a saturated carbon skeleton containing rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Gynecology & Obstetrics (AREA)
  • Hospice & Palliative Care (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Battery Electrode And Active Subsutance (AREA)
  • Manufacture Of Metal Powder And Suspensions Thereof (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)

Abstract

Procedimiento de obtención de la forma cristalina V del compuesto de fórmula (I):
UY0001032014A 2008-08-05 2009-07-28 Nuevo procedimiento de obtención de la forma cristalina v de la agomelatina UY32014A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0804466A FR2934856B1 (fr) 2008-08-05 2008-08-05 Nouveau procede d'obtention de la forme cristalline v de l'agomelatine

Publications (1)

Publication Number Publication Date
UY32014A true UY32014A (es) 2010-01-29

Family

ID=40418877

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001032014A UY32014A (es) 2008-08-05 2009-07-28 Nuevo procedimiento de obtención de la forma cristalina v de la agomelatina

Country Status (46)

Country Link
US (1) US8252957B2 (es)
EP (1) EP2151430B1 (es)
JP (1) JP5047240B2 (es)
KR (1) KR101118335B1 (es)
CN (1) CN101643432B (es)
AP (1) AP3196A (es)
AR (1) AR074889A1 (es)
AT (1) ATE518825T1 (es)
AU (1) AU2009203071B2 (es)
BR (1) BRPI0903058A2 (es)
CA (1) CA2674770C (es)
CL (1) CL2009001685A1 (es)
CO (1) CO6120151A1 (es)
CR (1) CR10952A (es)
CY (1) CY1111873T1 (es)
DK (1) DK2151430T3 (es)
EA (1) EA016896B1 (es)
EC (1) ECSP099554A (es)
ES (1) ES2371047T3 (es)
FR (1) FR2934856B1 (es)
GE (1) GEP20125408B (es)
GT (1) GT200900215A (es)
HK (1) HK1141005A1 (es)
HN (1) HN2009001437A (es)
HR (1) HRP20110712T1 (es)
IL (1) IL200126A (es)
JO (1) JO2812B1 (es)
MA (1) MA31223B1 (es)
ME (1) ME00929B (es)
MX (1) MX2009008046A (es)
MY (1) MY151042A (es)
NI (1) NI200900154A (es)
NZ (1) NZ578826A (es)
PE (1) PE20100153A1 (es)
PL (1) PL2151430T3 (es)
PT (1) PT2151430E (es)
RS (1) RS52002B (es)
SA (1) SA109300499B1 (es)
SG (1) SG158830A1 (es)
SI (1) SI2151430T1 (es)
SV (1) SV2009003345A (es)
TW (1) TW201008901A (es)
UA (1) UA102816C2 (es)
UY (1) UY32014A (es)
WO (1) WO2010015747A1 (es)
ZA (1) ZA200905334B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101781226B (zh) * 2009-12-23 2012-03-28 天津泰普药品科技发展有限公司 阿戈美拉汀及其药物组合物
WO2012093402A1 (en) * 2011-01-04 2012-07-12 Symed Labs Limited Processes for the preparation of n-[2-(7-methoxy-1-naphthyl)ethyl]acetamide
WO2012130837A1 (en) 2011-03-28 2012-10-04 Ratiopharm Gmbh Solid agomelatine in non-crystalline form
EP2872129B1 (en) 2012-07-16 2017-03-08 ratiopharm GmbH Complex of agomelatine and cyclodextrin
WO2015124496A1 (en) 2014-02-19 2015-08-27 Synthon B.V. Pharmaceutical composition comprising amorphous agomelatine

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1703641A1 (ru) * 1988-02-23 1992-01-07 Ростовский государственный университет Способ получени 3,5-ди-трет.бутил-4-оксиацетанилида
FR2658818B1 (fr) * 1990-02-27 1993-12-31 Adir Cie Nouveaux derives a structure naphtalenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
YU48420B (sh) * 1991-03-25 1998-07-10 Hoechst Aktiengesellschaft Postupak za dobijanje biološki razgradljivih mikročestica sa dugotrajnim delovanjem
FR2866335B1 (fr) * 2004-02-13 2006-05-26 Servier Lab Nouveau procede de synthese de l'agomelatine
FR2889521B1 (fr) * 2005-08-03 2007-12-28 Servier Lab Nouvelle forme cristalline iii de l'agomelatine, son procede de preparation et les compositions pharmaceutiques qui la contiennent
FR2889522B1 (fr) * 2005-08-03 2007-12-28 Servier Lab Nouvelle forme cristalline iv de l'agomelatine, son procede de preparation et les compositions pharmaceutiques qui la contiennent
FR2889523B1 (fr) * 2005-08-03 2007-12-28 Servier Lab Nouvelle forme cristalline v de l'agomelatine, son procede de preparation et les compositions pharmaceutiques qui la contiennent
WO2008141033A1 (en) * 2007-05-08 2008-11-20 Auspex Pharmaceuticals Inc. Substituted naphthalenes
FR2923482B1 (fr) * 2007-11-09 2010-01-29 Servier Lab Nouvelle forme cristalline vi de l'agomelatine, son procede de preparation et les compositions pharmaceutiques qui la contiennent

Also Published As

Publication number Publication date
EP2151430B1 (fr) 2011-08-03
TW201008901A (en) 2010-03-01
NZ578826A (en) 2010-11-26
IL200126A (en) 2013-04-30
CN101643432B (zh) 2012-12-12
DK2151430T3 (da) 2011-11-21
KR101118335B1 (ko) 2012-03-09
SI2151430T1 (sl) 2011-10-28
IL200126A0 (en) 2010-05-31
PE20100153A1 (es) 2010-03-06
FR2934856A1 (fr) 2010-02-12
CA2674770A1 (fr) 2010-02-05
EP2151430A1 (fr) 2010-02-10
US8252957B2 (en) 2012-08-28
MA31223B1 (fr) 2010-03-01
CO6120151A1 (es) 2010-01-29
MY151042A (en) 2014-03-31
MX2009008046A (es) 2010-03-23
CR10952A (es) 2009-10-15
CL2009001685A1 (es) 2010-07-19
AP2009004936A0 (en) 2009-08-31
ATE518825T1 (de) 2011-08-15
RS52002B (en) 2012-04-30
BRPI0903058A2 (pt) 2010-05-25
AR074889A1 (es) 2011-02-23
ECSP099554A (es) 2010-03-31
FR2934856B1 (fr) 2010-08-13
US20100036165A1 (en) 2010-02-11
SV2009003345A (es) 2010-02-01
AU2009203071B2 (en) 2013-10-31
EA200900944A1 (ru) 2010-04-30
HRP20110712T1 (hr) 2011-11-30
GEP20125408B (en) 2012-02-27
SA109300499B1 (ar) 2013-10-06
GT200900215A (es) 2011-07-19
ZA200905334B (en) 2010-05-26
HN2009001437A (es) 2011-09-22
NI200900154A (es) 2010-03-25
EA016896B1 (ru) 2012-08-30
SG158830A1 (en) 2010-02-26
JO2812B1 (en) 2014-09-15
AU2009203071A1 (en) 2010-02-25
WO2010015747A1 (fr) 2010-02-11
PT2151430E (pt) 2011-08-25
JP2010037345A (ja) 2010-02-18
HK1141005A1 (en) 2010-10-29
JP5047240B2 (ja) 2012-10-10
KR20100017070A (ko) 2010-02-16
CA2674770C (fr) 2012-04-17
CY1111873T1 (el) 2015-11-04
ME00929B (me) 2012-06-20
CN101643432A (zh) 2010-02-10
ES2371047T3 (es) 2011-12-26
AP3196A (en) 2015-03-31
PL2151430T3 (pl) 2011-12-30
UA102816C2 (ru) 2013-08-27

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20181112