UY29192A1 - Nuevas formulaciones de comprimidos de liberación modificada para inhibidores de bomba de protón - Google Patents
Nuevas formulaciones de comprimidos de liberación modificada para inhibidores de bomba de protónInfo
- Publication number
- UY29192A1 UY29192A1 UY29192A UY29192A UY29192A1 UY 29192 A1 UY29192 A1 UY 29192A1 UY 29192 A UY29192 A UY 29192A UY 29192 A UY29192 A UY 29192A UY 29192 A1 UY29192 A1 UY 29192A1
- Authority
- UY
- Uruguay
- Prior art keywords
- proton pump
- ppi
- modified release
- release tablets
- pump inhibitors
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Forma de dosificación farmacéutica oral sólida que comprende un inhibidor de la bomba de protones (PPI) como único fármaco activo, liberando la PPI en dos impulsos separados, uno inmediato y uno retardado. La PPI se formula con un material central en forma de gránulos que se recubren, entre otras cosas, con una combinación de una capa modificadora de liberación retardada y otra controladora del tiempo de retardo alcanzando juntas propiedades de liberación beneficiosas, procesos para preparar las formas de dosificación y aplicaciones en tratamiento de enfermedades gastrointestinales. Los gránulos se proporcionan, además, con una capa de revestimiento entérica.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US62562104P | 2004-11-04 | 2004-11-04 |
Publications (1)
Publication Number | Publication Date |
---|---|
UY29192A1 true UY29192A1 (es) | 2006-06-30 |
Family
ID=36319457
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY29192A UY29192A1 (es) | 2004-11-04 | 2005-11-04 | Nuevas formulaciones de comprimidos de liberación modificada para inhibidores de bomba de protón |
Country Status (17)
Country | Link |
---|---|
US (1) | US20080095853A1 (es) |
EP (1) | EP1809263A4 (es) |
JP (1) | JP2008519069A (es) |
KR (1) | KR20070073867A (es) |
CN (1) | CN101094660A (es) |
AR (1) | AR051654A1 (es) |
AU (1) | AU2005301368A1 (es) |
BR (1) | BRPI0517933A (es) |
CA (1) | CA2584417A1 (es) |
IL (1) | IL182696A0 (es) |
MX (1) | MX2007004986A (es) |
NO (1) | NO20072254L (es) |
RU (1) | RU2007115537A (es) |
TW (1) | TW200624127A (es) |
UY (1) | UY29192A1 (es) |
WO (1) | WO2006049564A1 (es) |
ZA (1) | ZA200703112B (es) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102406628A (zh) * | 2010-09-26 | 2012-04-11 | 上海复星普适医药科技有限公司 | 一种稳定的埃索美拉唑肠溶小丸的制备方法 |
DE102010052847A1 (de) * | 2010-11-29 | 2012-05-31 | Temmler Werke Gmbh | Verfahren zur Herstellung einer PPI-haltigen pharmazeutischen Zubereitung |
PT2647648T (pt) * | 2010-12-03 | 2017-10-02 | Nippon Soda Co | Forma de dosagem sólida que contém uma hidroxialquil celulose de baixa viscosidade |
AU2011352037A1 (en) * | 2010-12-29 | 2013-08-01 | Dr. Reddy's Laboratories Ltd. | Modified release benzimidazole formulations |
CN103565770A (zh) * | 2012-07-31 | 2014-02-12 | 北京阜康仁生物制药科技有限公司 | 一种右兰索拉唑肠溶缓控释微丸片 |
JP5819800B2 (ja) * | 2012-10-31 | 2015-11-24 | 信越化学工業株式会社 | 高粘度ヒプロメロースを分散したコーティング液及び固形製剤の製造方法 |
CN104586809A (zh) * | 2015-01-08 | 2015-05-06 | 浙江亚太药业股份有限公司 | 一种埃索美拉唑镁微丸肠溶片及制备方法 |
EP3288556A4 (en) | 2015-04-29 | 2018-09-19 | Dexcel Pharma Technologies Ltd. | Orally disintegrating compositions |
KR101884230B1 (ko) * | 2016-02-29 | 2018-08-01 | 주식회사 유영제약 | 에소메프라졸을 포함하는 제제 |
US10076494B2 (en) | 2016-06-16 | 2018-09-18 | Dexcel Pharma Technologies Ltd. | Stable orally disintegrating pharmaceutical compositions |
CN111991367A (zh) * | 2020-09-21 | 2020-11-27 | 青岛吉达巴尔国际贸易有限公司 | 一种埃索美拉唑镁脉冲微丸胶囊剂及制备方法 |
WO2022154687A1 (ru) * | 2021-01-14 | 2022-07-21 | Общество C Ограниченной Ответственностью "Новамедика" | Фармацевтическая композиция, включающая эзомепразол |
Family Cites Families (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL75400A (en) * | 1984-06-16 | 1988-10-31 | Byk Gulden Lomberg Chem Fab | Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same |
IT1230576B (it) * | 1988-10-20 | 1991-10-28 | Angeli Inst Spa | Formulazioni farmaceutiche per via orale a liberazione selettiva nel colon |
JPH07223970A (ja) * | 1994-02-10 | 1995-08-22 | Tanabe Seiyaku Co Ltd | 消化管内適所放出製剤 |
US5945124A (en) * | 1995-07-05 | 1999-08-31 | Byk Gulden Chemische Fabrik Gmbh | Oral pharmaceutical composition with delayed release of active ingredient for pantoprazole |
US20050054682A1 (en) * | 1996-01-04 | 2005-03-10 | Phillips Jeffrey O. | Pharmaceutical compositions comprising substituted benzimidazoles and methods of using same |
SE9600072D0 (sv) * | 1996-01-08 | 1996-01-08 | Astra Ab | New oral formulation of two active ingredients II |
CA2173818A1 (fr) * | 1996-04-10 | 1997-10-11 | Francois Chouinard | Comprime pharmaceutique a liberation controlee contenant un support a base d'amylose reticule et d'hydroxypropylmethylcellulose |
AU5179898A (en) * | 1996-11-06 | 1998-05-29 | Sharmatek, Inc. | Delayed delivery system for acid-sensitive drugs |
US5885616A (en) * | 1997-08-18 | 1999-03-23 | Impax Pharmaceuticals, Inc. | Sustained release drug delivery system suitable for oral administration |
SE9704870D0 (sv) * | 1997-12-22 | 1997-12-22 | Astra Ab | New pharmaceutical formulation I |
US6645503B1 (en) * | 1998-03-10 | 2003-11-11 | Wyeth Holdings Corporation | Antigenic conjugates of conserved lipopolysaccharides of gram negative bacteria |
CA2348871C (en) * | 1998-11-02 | 2009-04-14 | John G. Devane | Multiparticulate modified release composition |
US6632451B2 (en) * | 1999-06-04 | 2003-10-14 | Dexcel Pharma Technologies Ltd. | Delayed total release two pulse gastrointestinal drug delivery system |
EP1064938A1 (en) * | 1999-06-28 | 2001-01-03 | Sanofi-Synthelabo | Pharmaceutical dosage forms for controlled release producing at least a timed pulse |
EP1074249A1 (en) * | 1999-07-27 | 2001-02-07 | Jagotec Ag | A pharmaceutical tablet system for releasing at least one active substance during a release period subsequent to a no-release period |
ES2168043B1 (es) * | 1999-09-13 | 2003-04-01 | Esteve Labor Dr | Forma farmaceutica solida oral de liberacion modificada que contiene un compuesto de bencimidazol labil en medio acido. |
GB9923436D0 (en) * | 1999-10-04 | 1999-12-08 | American Home Prod | Pharmaceutical compositions |
US20030180352A1 (en) * | 1999-11-23 | 2003-09-25 | Patel Mahesh V. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
US6627223B2 (en) * | 2000-02-11 | 2003-09-30 | Eurand Pharmaceuticals Ltd. | Timed pulsatile drug delivery systems |
US6749867B2 (en) * | 2000-11-29 | 2004-06-15 | Joseph R. Robinson | Delivery system for omeprazole and its salts |
ATE376826T1 (de) * | 2001-09-28 | 2007-11-15 | Mcneil Ppc Inc | Darreichungsformen zur modifizierten freisetzung |
JP2003171277A (ja) * | 2001-12-07 | 2003-06-17 | Wyeth Lederle Japan Ltd | 薬物放出時間制御型固形製剤 |
AU2003250468A1 (en) * | 2002-08-16 | 2004-03-03 | Themis Laboratories Private Limited | A process for manufacture of stable oral multiple units pharamceutical composition containing benzimidazoles |
US8487002B2 (en) * | 2002-10-25 | 2013-07-16 | Paladin Labs Inc. | Controlled-release compositions |
US20040110781A1 (en) * | 2002-12-05 | 2004-06-10 | Harmon Troy M. | Pharmaceutical compositions containing indistinguishable drug components |
EP1596838A2 (en) * | 2003-02-11 | 2005-11-23 | Torrent Pharmaceuticals Ltd | Once a day orally administered pharmaceutical compositions comprising a proton pump inhibitor and a prokinetic agent |
US7670624B2 (en) * | 2004-01-29 | 2010-03-02 | Astella Pharma Inc. | Gastrointestinal-specific multiple drug release system |
JP2007532677A (ja) * | 2004-04-16 | 2007-11-15 | サンタラス インコーポレイティッド | プロトンポンプ阻害剤、緩衝剤、および運動促進薬の組み合わせ |
AR052225A1 (es) * | 2004-11-04 | 2007-03-07 | Astrazeneca Ab | Formulaciones de tabletas de liberacion modificada par inhibidores de la bomba de protones |
US20060165797A1 (en) * | 2005-01-12 | 2006-07-27 | Pozen Inc. | Dosage form for treating gastrointestinal disorders |
-
2005
- 2005-10-31 AR ARP050104548A patent/AR051654A1/es not_active Application Discontinuation
- 2005-11-02 MX MX2007004986A patent/MX2007004986A/es not_active Application Discontinuation
- 2005-11-02 RU RU2007115537/15A patent/RU2007115537A/ru unknown
- 2005-11-02 US US11/718,583 patent/US20080095853A1/en not_active Abandoned
- 2005-11-02 AU AU2005301368A patent/AU2005301368A1/en not_active Abandoned
- 2005-11-02 CN CNA2005800457444A patent/CN101094660A/zh active Pending
- 2005-11-02 JP JP2007540283A patent/JP2008519069A/ja active Pending
- 2005-11-02 EP EP05801799A patent/EP1809263A4/en not_active Withdrawn
- 2005-11-02 BR BRPI0517933-5A patent/BRPI0517933A/pt not_active Application Discontinuation
- 2005-11-02 KR KR1020077010116A patent/KR20070073867A/ko not_active Application Discontinuation
- 2005-11-02 CA CA002584417A patent/CA2584417A1/en not_active Abandoned
- 2005-11-02 WO PCT/SE2005/001642 patent/WO2006049564A1/en active Application Filing
- 2005-11-04 UY UY29192A patent/UY29192A1/es not_active Application Discontinuation
- 2005-11-04 TW TW094138679A patent/TW200624127A/zh unknown
-
2007
- 2007-04-16 ZA ZA200703112A patent/ZA200703112B/xx unknown
- 2007-04-19 IL IL182696A patent/IL182696A0/en unknown
- 2007-05-02 NO NO20072254A patent/NO20072254L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
RU2007115537A (ru) | 2008-12-10 |
TW200624127A (en) | 2006-07-16 |
BRPI0517933A (pt) | 2008-10-21 |
JP2008519069A (ja) | 2008-06-05 |
NO20072254L (no) | 2007-07-30 |
AR051654A1 (es) | 2007-01-31 |
ZA200703112B (en) | 2008-10-29 |
EP1809263A4 (en) | 2012-09-26 |
CA2584417A1 (en) | 2006-05-11 |
EP1809263A1 (en) | 2007-07-25 |
US20080095853A1 (en) | 2008-04-24 |
KR20070073867A (ko) | 2007-07-10 |
IL182696A0 (en) | 2007-09-20 |
AU2005301368A1 (en) | 2006-05-11 |
WO2006049564A1 (en) | 2006-05-11 |
WO2006049564A8 (en) | 2007-06-07 |
MX2007004986A (es) | 2007-06-14 |
CN101094660A (zh) | 2007-12-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
109 | Application deemed to be withdrawn |
Effective date: 20160525 |