UY28970A1 - Compuestos moduladores de la actividad de c-kit y usos de los mismos - Google Patents

Compuestos moduladores de la actividad de c-kit y usos de los mismos

Info

Publication number
UY28970A1
UY28970A1 UY28970A UY28970A UY28970A1 UY 28970 A1 UY28970 A1 UY 28970A1 UY 28970 A UY28970 A UY 28970A UY 28970 A UY28970 A UY 28970A UY 28970 A1 UY28970 A1 UY 28970A1
Authority
UY
Uruguay
Prior art keywords
same
modulating compounds
kit
kit activity
activity
Prior art date
Application number
UY28970A
Other languages
English (en)
Inventor
Prabha N Ibrahim
Clarence R Hurt
Chao Zhang
Jiazhong Zhang
Original Assignee
Plexxikon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Plexxikon Inc filed Critical Plexxikon Inc
Publication of UY28970A1 publication Critical patent/UY28970A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Compuestos con la estructura genérica 5-((1H-pirrol(2,3-b)piridin-3-il)metilo)-N-bencilpiridin-2-amina con actividad para el receptor de la proteína tirosina quinasa c-kit, se describen además composiciones útiles para el tratamiento de enfermedades o afecciones mediadas por c-kit y mctodos de uso de los mismos.
UY28970A 2004-06-17 2005-06-17 Compuestos moduladores de la actividad de c-kit y usos de los mismos UY28970A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58089804P 2004-06-17 2004-06-17
US68207605P 2005-05-17 2005-05-17

Publications (1)

Publication Number Publication Date
UY28970A1 true UY28970A1 (es) 2005-12-30

Family

ID=36034904

Family Applications (1)

Application Number Title Priority Date Filing Date
UY28970A UY28970A1 (es) 2004-06-17 2005-06-17 Compuestos moduladores de la actividad de c-kit y usos de los mismos

Country Status (2)

Country Link
US (2) US7498342B2 (es)
UY (1) UY28970A1 (es)

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US10160755B2 (en) 2015-04-08 2018-12-25 Plexxikon Inc. Compounds and methods for kinase modulation, and indications therefor
WO2017019804A2 (en) 2015-07-28 2017-02-02 Plexxikon Inc. Compounds and methods for kinase modulation, and indications therefor
CN113754656A (zh) 2015-09-21 2021-12-07 普莱希科公司 杂环化合物及其应用
BR112018011475A2 (pt) 2015-12-07 2018-12-04 Plexxikon Inc compostos e métodos para modulação de quinase e indicação para a mesma
US10160747B2 (en) 2016-03-16 2018-12-25 Plexxikon Inc. Compounds and methods for kinase modulation, and indications therefor
TW201815766A (zh) 2016-09-22 2018-05-01 美商普雷辛肯公司 用於ｉｄｏ及ｔｄｏ調節之化合物及方法以及其適應症
AU2017395023B2 (en) 2016-12-23 2022-04-07 Plexxikon Inc. Compounds and methods for CDK8 modulation and indications therefor
AU2018237047A1 (en) 2017-03-20 2019-10-17 Plexxikon Inc. Crystalline forms of 4-(1-(1,1-di(pyridin-2-yl)ethyl)-6-(3,5-dimethylisoxazol-4-yl)-1H- pyrrolo[3,2-b]pyridin-3-yl)benzoic acid that inhibits bromodomain
WO2018226846A1 (en) 2017-06-07 2018-12-13 Plexxikon Inc. Compounds and methods for kinase modulation
TWI805599B (zh) 2017-07-25 2023-06-21 美商第一三共公司 激酶調節化合物之調配物
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US20090105297A1 (en) 2009-04-23

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