UY26721A1 - Nuevos derivados de la fenilglicina - Google Patents
Nuevos derivados de la fenilglicinaInfo
- Publication number
- UY26721A1 UY26721A1 UY26721A UY26721A UY26721A1 UY 26721 A1 UY26721 A1 UY 26721A1 UY 26721 A UY26721 A UY 26721A UY 26721 A UY26721 A UY 26721A UY 26721 A1 UY26721 A1 UY 26721A1
- Authority
- UY
- Uruguay
- Prior art keywords
- phenylglycin
- new derivatives
- physiologically acceptable
- carbamimidoyl
- solvates
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/32—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D317/34—Oxygen atoms
- C07D317/36—Alkylene carbonates; Substituted alkylene carbonates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
- C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
- C07C257/18—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/12—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines
- C07C259/18—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines having carbon atoms of hydroxamidine groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/20—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Indole Compounds (AREA)
Abstract
El invento se refiere a nuevos derivados de N-(4 - carbamimidoil - fenil) - glicina de la fórmula I en donde X y R1 a R5 son como se ha definido en la descripción y reivindicaciones, así como hidratos o solvatos y/o sus sales fisiológicamente aceptables y/o sus ésteres fisiológicamente aceptables.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP00110881 | 2000-05-23 | ||
EP01960221A EP1289939A1 (en) | 2000-05-23 | 2001-05-17 | Phenylglycine derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
UY26721A1 true UY26721A1 (es) | 2001-12-28 |
Family
ID=8168800
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY26721A UY26721A1 (es) | 2000-05-23 | 2001-05-22 | Nuevos derivados de la fenilglicina |
Country Status (23)
Country | Link |
---|---|
US (1) | US6548694B2 (es) |
EP (1) | EP1289939A1 (es) |
JP (1) | JP3842132B2 (es) |
KR (1) | KR100569517B1 (es) |
CN (1) | CN1305839C (es) |
AR (1) | AR028596A1 (es) |
AU (2) | AU8177401A (es) |
BR (1) | BR0110998A (es) |
CA (1) | CA2408602C (es) |
EC (1) | ECSP024360A (es) |
HU (1) | HUP0302073A2 (es) |
IL (1) | IL152581A0 (es) |
MA (1) | MA26905A1 (es) |
MX (1) | MXPA02011466A (es) |
NO (1) | NO20025590D0 (es) |
NZ (1) | NZ522412A (es) |
PE (1) | PE20011314A1 (es) |
PL (1) | PL361355A1 (es) |
RU (1) | RU2268257C2 (es) |
UY (1) | UY26721A1 (es) |
WO (1) | WO2001090051A1 (es) |
YU (1) | YU83602A (es) |
ZA (1) | ZA200208899B (es) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ID29066A (id) * | 1998-12-14 | 2001-07-26 | Hoffmann La Roche | Turunan fenilglisina |
DE10300049A1 (de) * | 2003-01-03 | 2004-07-15 | Morphochem AG Aktiengesellschaft für kombinatorische Chemie | Neue Verbindungen, die Faktor VIIa inhibieren |
US6642386B2 (en) | 2002-02-06 | 2003-11-04 | Hoffmann-La Roche Inc. | N-(4-carbamimidoyl-phenyl)-glycine derivatives |
GB0211931D0 (en) * | 2002-05-23 | 2002-07-03 | Univ Liverpool | Methods & device utilizing adsorption of molecules at a surface or interface |
TW200410921A (en) * | 2002-11-25 | 2004-07-01 | Hoffmann La Roche | Mandelic acid derivatives |
JP2006517589A (ja) | 2003-02-11 | 2006-07-27 | ブリストル−マイヤーズ スクイブ カンパニー | セリンプロテアーゼ・インヒビターとして有用なベンゼンアセトアミド化合物 |
US7122559B2 (en) | 2003-02-11 | 2006-10-17 | Bristol-Myers Squibb Company | Phenylglycine derivatives useful as serine protease inhibitors |
DE10306202A1 (de) | 2003-02-13 | 2004-08-26 | Grünenthal GmbH | Arzneimittel enthaltend substituierte 2-Aryl-Aminoessigsäure-Verbindungen und/oder substituierte 2-Heteroaryl-Aminoessigsäure-Verbindungen |
US7917130B1 (en) | 2003-03-21 | 2011-03-29 | Stratosaudio, Inc. | Broadcast response method and system |
US7776804B2 (en) * | 2005-03-16 | 2010-08-17 | The Lubrizol Corporation | Viscosity improver compositions providing improved low temperature characteristics to lubricating oil |
US7056932B2 (en) | 2003-12-19 | 2006-06-06 | Hoffman-La Roche Inc. | Heterocyclyl substituted 1-alkoxy acetic acid amides |
JP4478157B2 (ja) * | 2004-10-13 | 2010-06-09 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ヒドラジド誘導体 |
WO2006045010A2 (en) * | 2004-10-20 | 2006-04-27 | Resverlogix Corp. | Stilbenes and chalcones for the prevention and treatment of cardiovascular diseases |
DE602006016566D1 (de) | 2005-01-10 | 2010-10-14 | Bristol Myers Squibb Co | Als antikoagulanzien verwendbare phenylglycinamid-derivate |
US7456195B2 (en) * | 2005-06-24 | 2008-11-25 | Bristol-Myers Squibb Company | Phenylglycinamide and pyridylglycinamide derivatives useful as anticoagulants |
US8044242B2 (en) | 2006-03-09 | 2011-10-25 | Bristol-Myers Squibb Company | 2-(aryloxy) acetamide factor VIIa inhibitors useful as anticoagulants |
ATE557010T1 (de) * | 2006-03-24 | 2012-05-15 | Eisai R&D Man Co Ltd | Triazolonderivat |
US7855194B2 (en) | 2006-03-27 | 2010-12-21 | Hoffmann-La Roche Inc. | Pyrimidine, quinazoline, pteridine and triazine derivatives |
CA2676984C (en) | 2007-02-01 | 2015-03-17 | Resverlogix Corp. | Compounds for the prevention and treatment of cardiovascular diseases |
EP1967522A1 (en) * | 2007-03-07 | 2008-09-10 | Novo Nordisk A/S | New blood coagulation factor inhibitors |
JPWO2009038157A1 (ja) * | 2007-09-21 | 2011-01-06 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 2,3−ジヒドロ−イミノイソインドール誘導体 |
WO2009079417A1 (en) | 2007-12-14 | 2009-06-25 | Stratosaudio, Inc. | Systems and methods for scheduling interactive media and events |
US8114995B2 (en) * | 2008-06-26 | 2012-02-14 | Resverlogix Corp. | Methods of preparing quinazolinone derivatives |
ES2542835T3 (es) | 2009-01-08 | 2015-08-12 | Resverlogix Corporation | Compuestos para la prevención y el tratamiento de enfermedades cardiovasculares |
JP5795304B2 (ja) | 2009-03-18 | 2015-10-14 | レスバーロジックス コーポレイション | 新規抗炎症剤 |
KR101892987B1 (ko) | 2009-04-22 | 2018-08-30 | 리스버로직스 코퍼레이션 | 신규한 소염제 |
CN102887836B (zh) * | 2011-07-18 | 2014-03-26 | 西南大学 | L-苯甘氨酸衍生物及其应用 |
CA2851996C (en) | 2011-11-01 | 2020-01-07 | Resverlogix Corp. | Pharmaceutical compositions for substituted quinazolinones |
GB201118876D0 (en) * | 2011-11-01 | 2011-12-14 | Astex Therapeutics Ltd | Pharmaceutical compounds |
WO2014080290A2 (en) | 2012-11-21 | 2014-05-30 | Rvx Therapeutics Inc. | Cyclic amines as bromodomain inhibitors |
WO2014080291A2 (en) | 2012-11-21 | 2014-05-30 | Rvx Therapeutics Inc. | Biaryl derivatives as bromodomain inhibitors |
EP2935253B1 (en) | 2012-12-21 | 2018-08-01 | Zenith Epigenetics Ltd. | Novel heterocyclic compounds as bromodomain inhibitors |
CA2977308A1 (en) | 2015-03-13 | 2016-09-22 | Resverlogix Corp. | Compositions and therapeutic methods for the treatment of complement-associated diseases |
CN111072562B (zh) * | 2019-11-07 | 2021-12-07 | 中山大学 | 一种四氢异喹啉衍生物及其制备方法和应用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SI0921116T1 (en) | 1997-12-04 | 2003-10-31 | F. Hoffmann - La Roche Ag | N-(4-carbamimido-phenyl)-glycine amide derivatives |
US6358960B1 (en) | 1998-02-17 | 2002-03-19 | Ono Pharmaceutical Co., Ltd. | Amidino derivatives and drugs containing the same as the active ingredient |
ID29066A (id) * | 1998-12-14 | 2001-07-26 | Hoffmann La Roche | Turunan fenilglisina |
-
2001
- 2001-05-16 US US09/858,535 patent/US6548694B2/en not_active Expired - Fee Related
- 2001-05-17 AU AU8177401A patent/AU8177401A/xx active Pending
- 2001-05-17 AU AU2001281774A patent/AU2001281774B2/en not_active Ceased
- 2001-05-17 YU YU83602A patent/YU83602A/sh unknown
- 2001-05-17 RU RU2002133215/04A patent/RU2268257C2/ru active
- 2001-05-17 MX MXPA02011466A patent/MXPA02011466A/es active IP Right Grant
- 2001-05-17 CA CA002408602A patent/CA2408602C/en not_active Expired - Fee Related
- 2001-05-17 KR KR1020027015798A patent/KR100569517B1/ko not_active IP Right Cessation
- 2001-05-17 EP EP01960221A patent/EP1289939A1/en not_active Withdrawn
- 2001-05-17 IL IL15258101A patent/IL152581A0/xx unknown
- 2001-05-17 JP JP2001586241A patent/JP3842132B2/ja not_active Expired - Fee Related
- 2001-05-17 PL PL36135501A patent/PL361355A1/xx not_active Application Discontinuation
- 2001-05-17 NZ NZ522412A patent/NZ522412A/en unknown
- 2001-05-17 WO PCT/EP2001/005633 patent/WO2001090051A1/en active IP Right Grant
- 2001-05-17 CN CNB018099297A patent/CN1305839C/zh not_active Expired - Fee Related
- 2001-05-17 HU HU0302073A patent/HUP0302073A2/hu unknown
- 2001-05-17 PE PE2001000442A patent/PE20011314A1/es not_active Application Discontinuation
- 2001-05-17 BR BR0110998-7A patent/BR0110998A/pt not_active IP Right Cessation
- 2001-05-21 AR ARP010102385A patent/AR028596A1/es not_active Application Discontinuation
- 2001-05-22 UY UY26721A patent/UY26721A1/es not_active Application Discontinuation
-
2002
- 2002-11-01 ZA ZA200208899A patent/ZA200208899B/en unknown
- 2002-11-21 NO NO20025590A patent/NO20025590D0/no not_active Application Discontinuation
- 2002-11-22 MA MA26921A patent/MA26905A1/fr unknown
- 2002-11-22 EC EC2002004360A patent/ECSP024360A/es unknown
Also Published As
Publication number | Publication date |
---|---|
PL361355A1 (en) | 2004-10-04 |
NO20025590L (no) | 2002-11-21 |
EP1289939A1 (en) | 2003-03-12 |
ECSP024360A (es) | 2003-03-31 |
AU2001281774B2 (en) | 2005-03-10 |
JP2003534311A (ja) | 2003-11-18 |
YU83602A (sh) | 2006-05-25 |
CA2408602A1 (en) | 2001-11-29 |
HUP0302073A2 (hu) | 2003-09-29 |
CN1305839C (zh) | 2007-03-21 |
IL152581A0 (en) | 2003-05-29 |
JP3842132B2 (ja) | 2006-11-08 |
NZ522412A (en) | 2004-05-28 |
MXPA02011466A (es) | 2003-04-25 |
WO2001090051A1 (en) | 2001-11-29 |
KR100569517B1 (ko) | 2006-04-07 |
US20020004608A1 (en) | 2002-01-10 |
KR20030007678A (ko) | 2003-01-23 |
CN1430599A (zh) | 2003-07-16 |
CA2408602C (en) | 2008-01-08 |
MA26905A1 (fr) | 2004-12-20 |
US6548694B2 (en) | 2003-04-15 |
BR0110998A (pt) | 2003-04-08 |
NO20025590D0 (no) | 2002-11-21 |
AR028596A1 (es) | 2003-05-14 |
RU2268257C2 (ru) | 2006-01-20 |
ZA200208899B (en) | 2004-02-19 |
PE20011314A1 (es) | 2002-01-04 |
AU8177401A (en) | 2001-12-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
109 | Application deemed to be withdrawn |
Effective date: 20140428 |