MXPA02011466A - Derivados de fenilglicina.. - Google Patents
Derivados de fenilglicina..Info
- Publication number
- MXPA02011466A MXPA02011466A MXPA02011466A MXPA02011466A MXPA02011466A MX PA02011466 A MXPA02011466 A MX PA02011466A MX PA02011466 A MXPA02011466 A MX PA02011466A MX PA02011466 A MXPA02011466 A MX PA02011466A MX PA02011466 A MXPA02011466 A MX PA02011466A
- Authority
- MX
- Mexico
- Prior art keywords
- phenylglycine derivatives
- physiologically acceptable
- derivatives
- solvates
- hydrates
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/32—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D317/34—Oxygen atoms
- C07D317/36—Alkylene carbonates; Substituted alkylene carbonates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
- C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
- C07C257/18—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/12—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines
- C07C259/18—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines having carbon atoms of hydroxamidine groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/20—Oxygen atoms
Abstract
La invencion se refiere a nuevos derivados de N- (4- carbamimidoil-fenil)-glicina de la formula (I); (Ver formula) en donde X y R1 a R5 son como se ha definido en la descripcion y en las reivindicaciones, asi como hidratos o solvatos y/o sus sales fisiologicamente aceptables y/o sus esteres fisiologicamente aceptables.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP00110881 | 2000-05-23 | ||
PCT/EP2001/005633 WO2001090051A1 (en) | 2000-05-23 | 2001-05-17 | Phenylglycine derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA02011466A true MXPA02011466A (es) | 2003-04-25 |
Family
ID=8168800
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA02011466A MXPA02011466A (es) | 2000-05-23 | 2001-05-17 | Derivados de fenilglicina.. |
Country Status (23)
Country | Link |
---|---|
US (1) | US6548694B2 (es) |
EP (1) | EP1289939A1 (es) |
JP (1) | JP3842132B2 (es) |
KR (1) | KR100569517B1 (es) |
CN (1) | CN1305839C (es) |
AR (1) | AR028596A1 (es) |
AU (2) | AU8177401A (es) |
BR (1) | BR0110998A (es) |
CA (1) | CA2408602C (es) |
EC (1) | ECSP024360A (es) |
HU (1) | HUP0302073A2 (es) |
IL (1) | IL152581A0 (es) |
MA (1) | MA26905A1 (es) |
MX (1) | MXPA02011466A (es) |
NO (1) | NO20025590D0 (es) |
NZ (1) | NZ522412A (es) |
PE (1) | PE20011314A1 (es) |
PL (1) | PL361355A1 (es) |
RU (1) | RU2268257C2 (es) |
UY (1) | UY26721A1 (es) |
WO (1) | WO2001090051A1 (es) |
YU (1) | YU83602A (es) |
ZA (1) | ZA200208899B (es) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100473966B1 (ko) * | 1998-12-14 | 2005-03-08 | 에프. 호프만-라 로슈 아게 | 페닐글리신 유도체 |
DE10300049A1 (de) * | 2003-01-03 | 2004-07-15 | Morphochem AG Aktiengesellschaft für kombinatorische Chemie | Neue Verbindungen, die Faktor VIIa inhibieren |
US6642386B2 (en) | 2002-02-06 | 2003-11-04 | Hoffmann-La Roche Inc. | N-(4-carbamimidoyl-phenyl)-glycine derivatives |
GB0211931D0 (en) * | 2002-05-23 | 2002-07-03 | Univ Liverpool | Methods & device utilizing adsorption of molecules at a surface or interface |
TW200410921A (en) * | 2002-11-25 | 2004-07-01 | Hoffmann La Roche | Mandelic acid derivatives |
US7144895B2 (en) | 2003-02-11 | 2006-12-05 | Bristol-Myers Squibb Co. | Benzene acetamide compounds useful as serine protease inhibitors |
EP1594505A4 (en) | 2003-02-11 | 2008-08-13 | Bristol Myers Squibb Co | PHENYLGLYCIN DERIVATIVES USEFUL AS SERINE PROTEASE INHIBITORS |
DE10306202A1 (de) | 2003-02-13 | 2004-08-26 | Grünenthal GmbH | Arzneimittel enthaltend substituierte 2-Aryl-Aminoessigsäure-Verbindungen und/oder substituierte 2-Heteroaryl-Aminoessigsäure-Verbindungen |
US7917130B1 (en) | 2003-03-21 | 2011-03-29 | Stratosaudio, Inc. | Broadcast response method and system |
US7776804B2 (en) * | 2005-03-16 | 2010-08-17 | The Lubrizol Corporation | Viscosity improver compositions providing improved low temperature characteristics to lubricating oil |
US7056932B2 (en) * | 2003-12-19 | 2006-06-06 | Hoffman-La Roche Inc. | Heterocyclyl substituted 1-alkoxy acetic acid amides |
WO2006041119A1 (ja) * | 2004-10-13 | 2006-04-20 | Eisai R & D Management Co., Ltd. | ヒドラジド誘導体 |
WO2006045096A2 (en) * | 2004-10-20 | 2006-04-27 | Resverlogix Corp. | Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases |
EP1856096B1 (en) | 2005-01-10 | 2010-09-01 | Bristol-Myers Squibb Company | Phenylglycinamide derivatives useful as anticoagulants |
ATE455103T1 (de) * | 2005-06-24 | 2010-01-15 | Bristol Myers Squibb Co | Als antikoagulationsmittel geeignete phenylglycinamid- und pyridylglycinamidderivate |
US8044242B2 (en) | 2006-03-09 | 2011-10-25 | Bristol-Myers Squibb Company | 2-(aryloxy) acetamide factor VIIa inhibitors useful as anticoagulants |
NZ571441A (en) * | 2006-03-24 | 2010-08-27 | Eisai R&D Man Co Ltd | Triazolone derivative |
US7855194B2 (en) | 2006-03-27 | 2010-12-21 | Hoffmann-La Roche Inc. | Pyrimidine, quinazoline, pteridine and triazine derivatives |
PT2118074E (pt) | 2007-02-01 | 2014-03-20 | Resverlogix Corp | Compostos para a prevenção e tratamento de doenças cardiovasculares |
EP1967522A1 (en) * | 2007-03-07 | 2008-09-10 | Novo Nordisk A/S | New blood coagulation factor inhibitors |
EP2202231A4 (en) * | 2007-09-21 | 2011-09-28 | Eisai R&D Man Co Ltd | 2,3-DIHYDROIMINOISOINDOLE DERIVATIVE |
US8631448B2 (en) | 2007-12-14 | 2014-01-14 | Stratosaudio, Inc. | Systems and methods for scheduling interactive media and events |
CA2711103C (en) | 2008-06-26 | 2016-08-09 | Resverlogix Corp. | Methods of preparing quinazolinone derivatives |
WO2010079431A2 (en) | 2009-01-08 | 2010-07-15 | Resverlogix Corp. | Compounds for the prevention and treatment of cardiovascular disease |
EP2408454A2 (en) | 2009-03-18 | 2012-01-25 | Resverlogix Corp. | Novel anti-inflammatory agents |
KR101892987B1 (ko) | 2009-04-22 | 2018-08-30 | 리스버로직스 코퍼레이션 | 신규한 소염제 |
CN102887836B (zh) * | 2011-07-18 | 2014-03-26 | 西南大学 | L-苯甘氨酸衍生物及其应用 |
GB201118876D0 (en) * | 2011-11-01 | 2011-12-14 | Astex Therapeutics Ltd | Pharmaceutical compounds |
JP5992049B2 (ja) | 2011-11-01 | 2016-09-14 | レスバーロジックス コーポレイション | 置換されたキナゾリノンのための経口速放性製剤 |
US9073878B2 (en) | 2012-11-21 | 2015-07-07 | Zenith Epigenetics Corp. | Cyclic amines as bromodomain inhibitors |
WO2014080291A2 (en) | 2012-11-21 | 2014-05-30 | Rvx Therapeutics Inc. | Biaryl derivatives as bromodomain inhibitors |
JP2016507496A (ja) | 2012-12-21 | 2016-03-10 | ゼニス・エピジェネティクス・コーポレイションZenith Epigenetics Corp. | ブロモドメイン阻害剤としての新規複素環式化合物 |
CN107530356A (zh) | 2015-03-13 | 2018-01-02 | 雷斯韦洛吉克斯公司 | 用于治疗补体相关疾病之组合物及治疗方法 |
CN111072562B (zh) * | 2019-11-07 | 2021-12-07 | 中山大学 | 一种四氢异喹啉衍生物及其制备方法和应用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0921116B1 (de) * | 1997-12-04 | 2003-06-18 | F. Hoffmann-La Roche Ag | N-(4-carbamimido-phenyl)-glycinamidderivate |
AU2300699A (en) * | 1998-02-17 | 1999-08-30 | Ono Pharmaceutical Co. Ltd. | Amidino derivatives and drugs containing the same as the active ingredient |
KR100473966B1 (ko) * | 1998-12-14 | 2005-03-08 | 에프. 호프만-라 로슈 아게 | 페닐글리신 유도체 |
-
2001
- 2001-05-16 US US09/858,535 patent/US6548694B2/en not_active Expired - Fee Related
- 2001-05-17 PL PL36135501A patent/PL361355A1/xx not_active Application Discontinuation
- 2001-05-17 CA CA002408602A patent/CA2408602C/en not_active Expired - Fee Related
- 2001-05-17 JP JP2001586241A patent/JP3842132B2/ja not_active Expired - Fee Related
- 2001-05-17 YU YU83602A patent/YU83602A/sh unknown
- 2001-05-17 IL IL15258101A patent/IL152581A0/xx unknown
- 2001-05-17 CN CNB018099297A patent/CN1305839C/zh not_active Expired - Fee Related
- 2001-05-17 MX MXPA02011466A patent/MXPA02011466A/es active IP Right Grant
- 2001-05-17 EP EP01960221A patent/EP1289939A1/en not_active Withdrawn
- 2001-05-17 NZ NZ522412A patent/NZ522412A/en unknown
- 2001-05-17 BR BR0110998-7A patent/BR0110998A/pt not_active IP Right Cessation
- 2001-05-17 AU AU8177401A patent/AU8177401A/xx active Pending
- 2001-05-17 AU AU2001281774A patent/AU2001281774B2/en not_active Ceased
- 2001-05-17 HU HU0302073A patent/HUP0302073A2/hu unknown
- 2001-05-17 PE PE2001000442A patent/PE20011314A1/es not_active Application Discontinuation
- 2001-05-17 KR KR1020027015798A patent/KR100569517B1/ko not_active IP Right Cessation
- 2001-05-17 RU RU2002133215/04A patent/RU2268257C2/ru active
- 2001-05-17 WO PCT/EP2001/005633 patent/WO2001090051A1/en active IP Right Grant
- 2001-05-21 AR ARP010102385A patent/AR028596A1/es not_active Application Discontinuation
- 2001-05-22 UY UY26721A patent/UY26721A1/es not_active Application Discontinuation
-
2002
- 2002-11-01 ZA ZA200208899A patent/ZA200208899B/en unknown
- 2002-11-21 NO NO20025590A patent/NO20025590D0/no not_active Application Discontinuation
- 2002-11-22 MA MA26921A patent/MA26905A1/fr unknown
- 2002-11-22 EC EC2002004360A patent/ECSP024360A/es unknown
Also Published As
Publication number | Publication date |
---|---|
NO20025590L (no) | 2002-11-21 |
YU83602A (sh) | 2006-05-25 |
PL361355A1 (en) | 2004-10-04 |
MA26905A1 (fr) | 2004-12-20 |
CA2408602A1 (en) | 2001-11-29 |
NZ522412A (en) | 2004-05-28 |
US20020004608A1 (en) | 2002-01-10 |
EP1289939A1 (en) | 2003-03-12 |
NO20025590D0 (no) | 2002-11-21 |
WO2001090051A1 (en) | 2001-11-29 |
BR0110998A (pt) | 2003-04-08 |
HUP0302073A2 (hu) | 2003-09-29 |
AU2001281774B2 (en) | 2005-03-10 |
ZA200208899B (en) | 2004-02-19 |
AR028596A1 (es) | 2003-05-14 |
ECSP024360A (es) | 2003-03-31 |
JP3842132B2 (ja) | 2006-11-08 |
JP2003534311A (ja) | 2003-11-18 |
KR20030007678A (ko) | 2003-01-23 |
PE20011314A1 (es) | 2002-01-04 |
RU2268257C2 (ru) | 2006-01-20 |
CA2408602C (en) | 2008-01-08 |
IL152581A0 (en) | 2003-05-29 |
CN1430599A (zh) | 2003-07-16 |
KR100569517B1 (ko) | 2006-04-07 |
UY26721A1 (es) | 2001-12-28 |
CN1305839C (zh) | 2007-03-21 |
US6548694B2 (en) | 2003-04-15 |
AU8177401A (en) | 2001-12-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration |